Eating leafy greens, dark orange and red vegetables and berry fruits, and drinking orange juice may be associated with a lower risk of memory loss over time in men, according to a study published in the November 21, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.
A team of neurologists at Georgetown University Medical Center has found that inhibiting the USP13 molecule may be a therapeutic target in Parkinson’s disease and other similar forms of neurodegeneration.
Rong Xu, PhD, recently received a total of $5 million for two projects that will use big data methods for a comprehensive look at a range of factors that may inform the mechanism of Alzheimer’s and related dementia.
Singing may provide benefits beyond improving respiratory and swallow control in people with Parkinson’s disease. New data revealed improvements in mood and motor symptoms, as well as reduced physiological indicators of stress.
A new study out of the Krembil Brain Institute, part of the Krembil Research Institute, suggests drinking coffee may protect you against developing both Alzheimer’s and Parkinson’s disease.
Rutgers scientists have created a tiny, biodegradable scaffold to transplant stem cells and deliver drugs, which may help treat Alzheimer’s and Parkinson’s diseases, aging brain degeneration, spinal cord injuries and traumatic brain injuries. Stem cell transplantation, which shows promise as a treatment for central nervous system diseases, has been hampered by low cell survival rates, incomplete differentiation of cells and limited growth of neural connections.
Description: Papers on inflammasomes and Parkinson’s disease; gas extraction and amphibian health; SeqAPASS; and androgen receptor HTS featured in latest issue of Toxicological Sciences.
In experiments performed in mice, Johns Hopkins researchers report they have identified the cascade of cell death events leading to the physical and intellectual degeneration associated with Parkinson's disease.
Removing the appendix early in life reduces the risk of developing Parkinson’s disease by 19 to 25 percent, according to the largest and most comprehensive study of its kind, published today in Science Translational Medicine.
A pioneer in the study of neural cells revealed today (Oct. 23, 2018) how a single mutation affecting the most common protein in a supporting brain cell produces devastating, fibrous globs. These, in turn, disturb the location of cellular processing units, harm the flow of energy and signals through the brain, and reduce the formation of myelin, an essential insulator for neurons.
The National Stem Cell Foundation (NSCF), Summit for Stem Cell Foundation, The New York Stem Cell Foundation (NYSCF) Research Institute, and Space Tango today announced a bi-coastal research collaboration to study Parkinson's disease (PD) and primary progressive multiple sclerosis (PPMS) in microgravity.
As the keynote speaker for the American Neurological Association's Presidential Symposium, “Lewy Body Dementia (LBD): From Symptoms to Synuclein,” Susan Schneider Williams put a human face on the leading-edge science presented at the session.
Embargoed abstracts to be presented at the American Neurological Association’s 143rd Annual Meeting October 21-23, 2018 at the Hyatt Regency Atlanta are now available to journalists upon request.
Methods to more precisely inject stem cells into the spinal cord; an enzyme that enhances the synthesis of dopamine in people with Parkinson’s disease; a drug that protects against chemotherapy-induced neuropathy – these are just a few of the exciting research findings that will be presented at the American Neurological Association’s 143rd Annual Meeting October 21-23, 2018 at the Hyatt Regency Atlanta.
A briefing featuring key data presented at the 6th International Symposium on Focused Ultrasound. Researchers and clinicians will highlight breakthrough advances in the use of focused ultrasound in cancer immunotherapy and for opening the blood-brain barrier (BBB).
UT Southwestern researchers attempting to transform supporting brain cells into neurons instead reprogrammed mature inhibitory neurons into a different type of neuron that creates the neurotransmitter lost in Parkinson’s disease.
People with a particular kind of irregular heartbeat called atrial fibrillation may experience a faster decline in thinking and memory skills and have a greater risk of dementia than those without atrial fibrillation, according to a study published in the October 10, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Peter Konrad, MD, presents exciting findings that show Deep Brain Stimulation (DBS) of the subthalamic nucleus (STN) in early stage Parkinson’s Disease may slow tremor progress at the Congress of Neurological Surgeon’s (CNS) 2018 Annual Meeting in Houston, Texas.
A team of physicists has devised a novel strategy that uses naturally occurring motions inside the human cell nucleus to measure the physical properties of the nucleus and its components. The method offers a potential new means for illuminating the physical properties of unhealthy cells, such as those linked to Alzheimer’s and Parkinson’s disease.
There is a missing link between genetic and environmental causes of Parkinson’s disease, speculate scientists at UAB, and armed with a $2.5 million grant from the U.S. Army Medical Research and Materiel Command, they intend to find it.
Penn Medicine's new Molecular Integration in Neurological Diagnosis Initiative brings the power of precision medicine to Parkinson’s disease research.
A new poll shows that only a small percentage of people in their 50s and early 60s have had their DNA tested – either for medical reasons, to learn their ancestry or out of curiosity – but far more have an interest in getting tested. However, two thirds said genetic testing could lead them to worry too much about their future health.
In the wake of media and public reports about increased mortality linked to a new drug for treating Parkinson’s disease psychosis, researchers at University of California San Diego School of Medicine conducted a retrospective study of qualifying patients in the UC San Diego Health system concluding that the new drug, pimavanserin (marketed as Nuplazid), did not pose a statistically significant greater risk of death.
Researchers at University of Utah Health found that ADHD patients had an increased risk of developing Parkinson’s and Parkinson-like diseases than individuals with no ADHD history.
Small, New World monkeys called marmosets can mimic the sleep disturbances, changes in circadian rhythm, and cognitive impairment people with Parkinson’s disease develop, according to a new study by scientists at Texas Biomedical Research Institute.
Inflammation is the body’s reaction to a harmful stimulus, such as infection with a virus like the flu, an injury like a cut or scrape or chronic conditions such as Crohn’s disease. Although it is a normal and important part of our immune system’s defenses, when it sticks around too long it can be
Researchers found a new cell surface marker on stem cells induced to become dopamine neurons, which allow isolation of a more beneficial population of induced neurons for cell replacement therapy. Animals that received a transplant sorted using the new marker fared better than their counterparts with a typical transplant.
Electrical stimulation of the brain and spinal cord may help treat the symptoms of rare movement disorders called neurodegenerative ataxias, according to a study published in the August 22, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.
The eyes may be a window to the brain for people with early Parkinson’s disease. People with the disease gradually lose brain cells that produce dopamine, a substance that helps control movement. Now a new study has found that the thinning of the retina, the lining of nerve cells in the back of the eye, is linked to the loss of such brain cells. The study is published in the August 15, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Researchers in the Department of Physical Medicine and Rehabilitation at Johns Hopkins Medicine report that a computerized study of 36 healthy adult volunteers asked to repeat the same movement over and over became significantly faster when asked to repeat that movement on demand—a result that occurred not because they anticipated the movement, but because of an as yet unknown mechanism that prepared their brains to replicate the same action.
Tulane University research could shed light on the molecular details of Alzheimer’s and Parkinson’s.
Iowa State University biomedical scientists are examining how exposure to the metals manganese and vanadium may contribute to Parkinson’s disease. The research was supported recently by a nearly $1 million grant from the U.S. Army Medical Research Acquisition Activity.
There is new hope for the treatment of Alzheimer’s and other neurological diseases following a ground-breaking discovery made by an Australian-Chinese research collaboration.
Work on the camera for the future Large Synoptic Survey Telescope (LSST) has reached a major milestone with the completion and delivery of the camera’s fully integrated cryostat. With 3.2 gigapixels, the LSST camera will be the largest digital camera ever built for ground-based astronomy. It’s being assembled at the Department of Energy’s SLAC National Accelerator Laboratory.
Parkinsonism – slowed movement, muscle rigidity and tremor – is a classic set of neurological symptoms most often seen in patients with Parkinson’s disease. Because neuron loss in the substantia nigra – a region of the brain associated with motor planning – is the hallmark characteristic of Parkinson’s disease, parkinsonism has long been thought to originate there. However, parkinsonism can occur in patients who have other conditions that leave the substantia nigra intact, making the true source of the suite of symptoms a mystery.
In a study published online July 25 in the journal Nature, University of California San Diego School of Medicine researchers identified a signaling pathway that activates the NLRP3 inflammasome implicated in several severe chronic inflammatory disorders.
Aberrant clearance activity of microglia in particular brain regions leads to changes associated with neurodegenerative diseases
A drug currently in clinical trials for treating symptoms of Parkinson’s disease may someday have value for treating heart failure, according to results of early animal studies by Johns Hopkins Medicine researchers.
Mayfield Brain & Spine joins over 100 existing QOD participating centers.
New research from South Australian scientists has shown that vitamin D (also commonly known as the sunshine vitamin) is unlikely to protect individuals from multiple sclerosis, Parkinson’s disease, Alzheimer’s disease or other brain-related disorders.
Nearly all major neurodegenerative diseases are defined by the presence of one of four proteins that have gone rogue. As such, investigational drugs aimed at preventing or slowing the disease often hone in on just one of these proteins. However, targeting multiple proteins at once may be the real key, according to a recent Penn Medicine study.
Johns Hopkins researchers say they have developed an experimental drug, similar to compounds used to treat diabetes, that slows the progression of Parkinson’s disease itself — as well as its symptoms — in mice.
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