Administering needle-based procedures in anesthesiology, such as epidurals, is a complex and delicate procedure. However, the current training methods for doctors are costly and fall shor
Researchers have shown — for the first time — that established lung fibrosis can be reversed using a drug treatment that targets cell metabolism. This is important because, despite significant advances in the pathological mechanisms of persistent fibrosis, effective interventions are lacking.
Researchers in the School of Public Health are conducting a clinical trial to see whether psilocybin, the active compound found in Psilocybe mushrooms, will help individuals addicted to cocaine stop using the harmful drug.
Hackensack Meridian Health Bayshore Medical Center in Holmdel is now home to the da Vinci® Si™ Surgical system, bringing advanced technology in surgery to the medical center’s operating room and to the community. Robotic surgery enables surgeons to perform minimally invasive surgeries on a variety of diseases and conditions including urology, gynecology and general surgery.
Higher daily doses of rifampin, a cornerstone of tuberculosis treatment, killed more TB bacteria in sputum cultures, and the higher doses did so without increasing the adverse effects of treatment, according to a randomized controlled trial published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.
Beginning July 1, James M. Musser, M.D., Ph.D., becomes the 2018-2019 president of the Federation of American Societies for Experimental Biology (FASEB).
A study by a team that includes Amrita Banerjee, assistant professor of pharmaceutical sciences at North Dakota State University, Fargo, shows promise in administering insulin in pill form. Banerjee is listed as first author in the study published in the Proceedings of the National Academy of Sciences.
The research offers another approach for tackling diseases that have been considered "undruggable," including amyotrophic lateral sclerosis (ALS), muscular dystrophy, cystic fibrosis and certain cancers.
AACC, a global scientific and medical professional organization dedicated to better health through laboratory medicine, is pleased to announce that the impact factor of its journal, Clinical Chemistry, has risen to 8.636 in the 2017 Thomson Reuters Journal Citation Reports. This impact factor places Clinical Chemistry in the top 2.5% of 12,271 ranked academic journals and speaks to the significant influence of the science it publishes on laboratory medicine and patient care.
With applications for asylum in the United States increasing sharply, a new paper from a team of asylum medicine and law experts is highlighting physicians’ important role in evaluating refugees’ claims of torture and persecution.
University of Utah President Ruth V. Watkins has appointed Michael L. Good, M.D., as the university’s new senior vice president for health sciences, CEO of University of Utah Health, and executive dean of the U’s School of Medicine.
Drs. Kenneth Shroyer and Luisa Escobar-Hoyos receive $500,000 from PanCAN to advance research
Millions of samples of blood, saliva, tissue and much more will receive advanced testing at new facility built as part of a $160 million project to serve patients around the state and nation.
Clinical Research Pathways has launched an effort to learn what information and other resources physicians need to seek access to experimental drugs for desperately ill or terminal patients, using the expanded access program.
To improve water treatment, researchers use modeling to understand how chemical byproducts form during the advanced oxidation process.
To aid in the discovery and understanding of lncRNA biology, newly published work features the technological platforms and methodology presently used to identify the roles of lncRNA in biology. This work highlights the databases and tools used to study lncRNA and techniques used to study their function.
New research, published this month by the American Pain Society (APS), adds to burgeoning scientific evidence showing that interdisciplinary pain rehabilitation programs are an effective alternative to opioids for chronic pain management. Despite several studies documenting favorable outcomes, access to multi-modal pain management programs remains out of reach for most patients due to inadequate insurance coverage. This discourages providers from opening new interdisciplinary pain clinics.
The American Pain Society today announced its selections of clinical psychologist Tonya Palermo, Ph.D. as Treasurer and three new members of the Board of Directors: John Markman, M.D., Jamie Rhudy, Ph.D. and David Tauben, M.D.
ISPOR, the professional society for health economics and outcomes research, announced a new ISPOR Summit “New Approaches to Value Assessment: Towards More Informed Pricing in Healthcare” scheduled for October 19, 2018 in Washington, DC, USA.
A genetic anomaly in certain men with prostate cancer may impact their response to common drugs used to treat the disease, according to new research at Cleveland Clinic. The findings may provide important information for identifying which patients potentially fare better when treated with an alternate therapy.
A team of researchers at Johns Hopkins have found that activating nerve cell receptors along two chemical pathways — one that has previously been linked to how the brain senses “itch” — may improve pain relief when combined with conventional ways to blunt pain using opioid drugs, such as morphine.
Microbiologist Aimee Shen at Tufts University School of Medicine is one of 12 new recipients nationwide of the Burroughs Wellcome Fund 2018 Investigators in the Pathogenesis of Infectious Disease (PATH) award for her research on Clostridium difficile.
A new study to be published online June 25 in JAMA Internal Medicine reports that hospital at home (HaH) care provides a shorter length of stay; reductions in hospital readmissions, emergency department visits, and transfers to skilled nursing facilities; and, improved patient experience versus traditional inpatient care. The study, which spans nearly three years, includes patients with the broadest set of admitting diagnoses ever to be researched, thus strengthening the evidence base for hospital at home care.
A new study published online today by Pediatrics and conducted by researchers at the Center for Injury Research and Policy and the Central Ohio Poison Center at Nationwide Children’s Hospital found that from January 2007 through December 2016 there were more than 11,000 calls to US Poison Centers for pediatric exposures to buprenorphine.
Breaking News!! The House of Representatives minutes ago just passed legislation to allow nurse anesthetists and other APRNs to administer medical-assisted medicine independently in an effort to fight the opioid crisis by increasing access to treatment for individuals who are addicted.
It’s been known for years that humans and other mammals possess an antiviral gene called RSAD2 that prevents a remarkable range of viruses from multiplying. Now, researchers at Albert Einstein College of Medicine, part of Montefiore, have discovered the secret to the gene’s success: The enzyme it codes for generates a compound that stops viruses from replicating. The newly discovered compound, described in today’s online edition of Nature, offers a novel approach for attacking many disease-causing viruses.
Health care insurers including Medicare, Medicaid and major private insurers have not done enough to combat the opioid epidemic, suggests a study led by researchers at Johns Hopkins Bloomberg School of Public Health.
In the first 90 days of concurrent opioid and benzodiazepine use, the risk of opioid-related overdose increases five-fold compared to opioid-only use among Medicare recipients, according to a new study from the University of Pittsburgh School of Pharmacy.
Cardiologist Dr. James de Lemos, Professor of Internal Medicine, and pediatrician Dr. Dorothy Sendelbach, Assistant Dean of Undergraduate Medical Education at UT Southwestern, have been recognized with the UT System’s highest educational honor, the Regents’ Outstanding Teaching Awards, for their academic prowess and mentoring talent.
Promising experimental cancer chemotherapy drugs may help knock out another life-threatening disease: tuberculosis (TB).
In contrast to most antidepressant medications, which can take several weeks to reduce depressive symptoms, ketamine — a commonly used veterinary anesthetic — can lift a person out of a deep depression within minutes of its administration, and its effects can last several weeks. Researchers have long-wondered how ketamine can both act quickly and be so long-lasting.
The microbiome may harbor a gene for drug resistance
Michigan Medicine researchers discover that stimulating the prefrontal cortex results in wake-like behavior in anesthetized rats.
West Virginia University researchers are working to improve screening rates for the state, which has one of the highest incidences of colorectal cancer and one of the lowest screening rates in the nation.
With microbial resistance to antibiotics growing into a major global health crisis, researchers at University of California San Diego School of Medicine, in collaboration with national research institutions and private industry, are leveraging hard-won expertise to exploit a natural viral enemy of pathogenic bacteria, creating North America’s first Center for Innovative Phage Applications and Therapeutics (IPATH).
A new study shows in an emergency, 52 percent of adults with potentially life-threatening allergies didn’t use the epinephrine auto-injectors (EAI) they were prescribed.
A new SLAS Discovery review article summarizes new methods of fragment-based lead discovery (FBLD) to identify new compounds as potential antibiotics. It explains how FBLD works and illustrates its advantages over conventional high-throughput screening.
When Jimmy Carter was diagnosed with end-stage metastatic melanoma in 2015, he began taking a drug developed in part using 3D molecular data. Insights like these into drug discovery and other fields of scientific research are possible using the 140,000-plus 3D molecular structures made freely available in the RCSB Protein Data Bank at Rutgers University–New Brunswick.
In an article published today in the New England Journal of Medicine, University of Pennsylvania researchers call for modernizing the way Medicare pays for training nurses, and highlight a successful new model of cost-effectively training more advanced practice nurses to practice community-based primary care.
Over time, half of the people taking certain drugs for Parkinson’s disease may develop impulse control disorders such as compulsive gambling, shopping or eating, according to a study published in the June 20, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Cornell University researchers have discovered there is a division of labor among immune cells that fight invading pathogens in the body.
In recent articles in Molecular & Cellular Proteomics, scientists optimize experimental design for understanding potential chemotherapeutic agents, delve into crop responses to salt-water stress, and present a better way to ensure consistency in long-term proteomics studies.
A new SLAS Discovery review article by GlaxoSmithKline researchers in the U.S. and U.K. offers an informative guide to the established and emerging tools available for early drug discovery and screening, and provides illustrative scenarios demonstrating considerations that drive decisions on choice of lead discovery tactics.
Researchers at the Princess Margaret Cancer Centre in Toronto have discovered that epigenetic proteins promote the proliferation of mammary gland stem cells in response to the sex hormone progesterone. The study, which will be published June 19 in the Journal of Cell Biology, suggests that inhibiting these proteins with drugs could prevent the development of breast cancer in women at high risk of the disease.
Value in Health, the official journal of ISPOR (the professional society for health economics and outcomes research), announced today the publication of a study introducing a novel strategy for obtaining reasonable drug cost estimates for US-based cost-effectiveness analyses.
Results Do Not Support Routine Use of This Expensive Drug
Researchers from the Icahn School of Medicine at Mount Sinai found an elevated risk of major congenital malformations in fetuses after first-trimester exposure to lithium, in the largest study ever to examine the risk of birth defects in lithium-exposed babies.
A JAMA Pediatrics study shows that since 2003, the use of alternative medicines among children has doubled. Increased use of Omega-3 fatty acids and melatonin among adolescents ages 13 to 18 drives the change.
Scripps Research scientists have solved a major problem in chemistry and drug development by using droplet-sized ‘miniecosystems’ to quickly see if a molecule can function as a potential therapeutic.
"This new method should allow us to explore a large ‘chemical space’ that had been essentially off-limits."
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