The American Society for Pharmacology and Experimental Therapeutics (ASPET) has selected 16 individuals as 2023 ASPET Fellows.
Stay informed! Keep up with the latest research on the COVID-19 virus in the Coronavirus channel on Newswise.
Cleveland Clinic researchers analyzed genes and brain tissue of patients with Alzheimer’s and found that differences in brain immunometabolism – the interactions between the immune system and the ways cells create energy – may contribute to women’s increased risk for the disease and its severity.
A new study shows that a drug that boosts bone growth in children with achondroplasia, the most common form of dwarfism, may also reduce their chances of sudden infant death syndrome (SIDS), sleep apnea, and needing surgery.
Proof of concept of new material for long lasting relief from dry mouth conditions
Researchers at Chalmers University of Technology have developed a new method to capture many proteins in nano-sized traps. This method can be used to study the formation of protein clumps, which are linked to many diseases.
University of B.C. researchers have uncovered startling connections between micronutrient deficiencies and the composition of gut microbiomes in early life that could help explain why resistance to antibiotics has been rising across the globe.
Migraine is more than just a headache. Often the pain is accompanied by nausea, vomiting, light sensitivity, and sound sensitivity. Chronic migraine can be disabling and may prevent many, especially women, from contributing to working life.
Redispensing cancer drugs reduces both environmental impact and medical costs, according to research from Radboudumc pharmacy published in JAMA Oncology. The annual savings could amount to tens of millions.
An analysis of U.S. Food and Drug Administration (FDA) and patent records revealed how manufacturers have extended periods of market exclusivity for brand-name insulin products.
La epilepsia descontrolada de Lisa Lindahl la obligó a ser creativa a la hora de trabajar. En 1977 inventó el sujetador deportivo, que cambió la vida de miles de millones de mujeres y niñas en todo el mundo, y ahora es un mercado global de 40.000 millones de dólares.
A study showed that patient pain scores were a good predictor for opioid use, but younger patients and those who hadn’t used opioids before were less likely to take them
Sarosh Rana, MD, MPH has been named the inaugural Chief Obstetrical Transformation Officer for the University of Chicago Medicine health system.
MCRA, LLC, a leading medical device and biologics focused clinical research organization (CRO) and advisory firm integrating seven core services [U.S. and International Regulatory Affairs, Clinical Trial Operations, Reimbursement and Market Access, Healthcare Compliance, Cybersecurity, Quality Assurance, and Japan Distribution Logistics (DMAH)] is pleased to announce the hiring of Dr. Carolyn Yong and Dr. Iris Marklein as the Vice President and Senior Director, respectively, of Regulatory Affairs for Regenerative Medicine and Biologics Quality.
An existing drug that targets senescent, or sleeping cells could provide the answer to treating lower back pain, according to a new study.
Genomic surveillance of AMR pathogens has the potential to revolutionize AMR control, but barriers such as lack of resources and training need to be overcome.
By: Bill Wellock | Published: November 14, 2023 | 2:43 pm | SHARE: The U.S. Food and Drug Administration recently approved the medication Zepbound for weight management treatment.Tirzepatide, the active ingredient in the Eli Lilly and Company’s trademarked Zepbound, was already approved to help improve blood sugar (glucose) in adults with type 2 diabetes mellitus.
A first-of-its-kind study has identified overactive inflammation and loss of critical protection mechanisms in the brain as potential contributors to suicide risk.
Researchers at the University of Leicester have discovered the mechanism by which cholesterol in our diet is absorbed into our cells
The American Association of Physicists in Medicine is pleased to announce C. David Gammel as its incoming Executive Director.
Physicists from the University of Luxembourg together with experts from Avant-garde Materials Simulation (AMS) and seven pharmaceutical companies have redefined the state-of-the-art in modeling and predicting the free energy of crystals.
Recycled plastic contains hundreds of toxins, scientists say, urging ban on hazardous chemicals.
New device could improve the outcomes of cell-based therapies
UCLA researchers have described a previously unknown step in the complex process by which dietary cholesterol is processed in the intestines before being released into the bloodstream – potentially revealing a new pathway to target in cholesterol treatment.
A new study being presented at this year’s ACAAI Annual Scientific Meeting in Anaheim, Calif. shows that language difficulties may cause some children to be underdiagnosed for allergic conditions such as food allergy, asthma and eczema. In addition, a new medically challenging case illustrates it is possible for pharmacy translation software to mistakenly interfere with a prescription being filled.
Asian malaria mosquito found to spread drug and diagnosis-resistant malaria in Africa.
Research consortium investigators analyzed over 314,000 cells from rheumatoid arthritis tissue, defining six types of inflammation involving diverse cell types and disease pathways
Transient inflammatory pain causes long-lasting mitochondrial changes in sensory neurons, contributing to chronic pain.
New hope for other nervous system disorders like ALS
Forward Therapeutics, Inc., a biopharmaceutical company developing next-generation small molecule therapies for chronic immunological and inflammatory disorders, today announced a $50 million Series A financing.
Children’s Hospital Los Angeles has launched a new clinical trial to investigate a potential treatment for Dup15q syndrome, a rare genetic condition that causes developmental delays, autism spectrum disorder and epilepsy.
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In a proof-of-concept in ACS’ Nano Letters, a team has designed injectable nanoparticles that released naloxone ― which rapidly reverses opioid overdose effects ― when triggered by blue light. In experiments with mice, this system was activated a month after injection.
New research in the November 2023 issue of JNCCN—Journal of the National Comprehensive Cancer Network suggests that breast cancer patients who have insufficient levels of vitamin D before starting paclitaxel treatment are more likely to experience peripheral neuropathy.
Scientists find the use of oral contraceptives may affect fear-related brain morphology, knowledge that could deepen understanding of fear-related mechanisms that primarily affect women
SOPHiA GENETICS (Nasdaq: SOPH), a cloud-native software company and a leader in data-driven medicine, today announced that BioReference® Health, LLC, an OPKO Health, Inc. company and full-service laboratory that processes more than 12 million tests annually, will implement SOPHiA GENETICS' technology and add MSK-ACCESS® liquid biopsy to its test suite.
MD Anderson and Jazz Pharmaceuticals announced a five-year strategic research collaboration agreement to evaluate zanidatamab, Jazz’s investigational HER2-targeted bispecific antibody, in multiple HER2-expressing cancers.
Value in Health announced the publication of a study showing that United States Medicare could save up to an additional $5-$10 billion dollars annually across 10 drugs if it negotiated prices using a therapeutic reference pricing approach rather than using the statutory ceiling price alone.
Rakuten Medical, Inc., a global biotechnology company developing and commercializing precision, cell-targeted therapies based on its proprietary Alluminox™ platform today announced the presentation of two posters of AI-based analyses at the 38th Annual Meeting of the Society for Immunotherapy of Cancer (SITC), held November 3-5, 2023, in San Diego, CA (SITC 2023).
A new targeted drug, studied by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James), may offer a new treatment option for patients with blood cancers, including chronic lymphocytic leukemia and Non-Hodgkin lymphoma whose disease has stopped responding to standard treatments.
Researchers combined the features of clinical drugs to treat hepatitis C and viruses similar to COVID-19. This allowed them to synthesize BBH-1, a promising inhibitor that targets the breakdown of the SARS-CoV-2 virus. The researchers characterized samples using X-ray and neutron diffraction techniques to provide atomic-level insights on the structure of the BBH-1 inhibitor and how it binds to the SARS-CoV-2 protein.
By leveraging the power of oxygen, these gelatin patches can act as effective tissue adhesives that accelerate the healing of wounds
The ERP Biomarker Qualification Consortium announced today that they will be presenting data from a recently completed, pharma industry sponsored study that measured the electrophysiologic effects of ketamine on healthy brain function, at the CNS Summit 2023 in Boston.
Antibiotic-resistant bacteria pose a major challenge to healthcare systems worldwide. Due to numerous resistance mechanisms, infections with the pathogen Pseudomonas aeruginosa are particularly feared. Researchers at the German Center for Infection Research (DZIF), the University Hospital Cologne, the Helmholtz Centre for Infection Research in Braunschweig and the University Medical Center Hamburg-Eppendorf have now discovered antibodies that could lead to a highly potent treatment option of acute and chronic infections with P. aeruginosa. The study was published in the prestigious scientific journal Cell.
A new Cochrane review has found that insulin can be kept at room temperature for months without losing potency, offering hope to people living with diabetes in regions with limited access to healthcare or stable powered refrigeration
Cancer drug could treat inflammatory diseases by calming down the inflammatory response
FragDPI, a novel drug-protein interaction prediction method, outperforms baselines and identifies specific interaction parts, aiding drug discovery
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