Feature Channels: Pharmaceuticals

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La epilepsia descontrolada de Lisa Lindahl la obligó a ser creativa a la hora de trabajar. En 1977 inventó el sujetador deportivo, que cambió la vida de miles de millones de mujeres y niñas en todo el mundo, y ahora es un mercado global de 40.000 millones de dólares.

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A study showed that patient pain scores were a good predictor for opioid use, but younger patients and those who hadn’t used opioids before were less likely to take them

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Sarosh Rana, MD, MPH has been named the inaugural Chief Obstetrical Transformation Officer for the University of Chicago Medicine health system.

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Genomic surveillance of AMR pathogens has the potential to revolutionize AMR control, but barriers such as lack of resources and training need to be overcome.

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By: Bill Wellock | Published: November 14, 2023 | 2:43 pm | SHARE: The U.S. Food and Drug Administration recently approved the medication Zepbound for weight management treatment.Tirzepatide, the active ingredient in the Eli Lilly and Company’s trademarked Zepbound, was already approved to help improve blood sugar (glucose) in adults with type 2 diabetes mellitus.

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A first-of-its-kind study has identified overactive inflammation and loss of critical protection mechanisms in the brain as potential contributors to suicide risk.

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The American Association of Physicists in Medicine is pleased to announce C. David Gammel as its incoming Executive Director.

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New device could improve the outcomes of cell-based therapies

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UCLA researchers have described a previously unknown step in the complex process by which dietary cholesterol is processed in the intestines before being released into the bloodstream – potentially revealing a new pathway to target in cholesterol treatment.

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A new study being presented at this year’s ACAAI Annual Scientific Meeting in Anaheim, Calif. shows that language difficulties may cause some children to be underdiagnosed for allergic conditions such as food allergy, asthma and eczema. In addition, a new medically challenging case illustrates it is possible for pharmacy translation software to mistakenly interfere with a prescription being filled.

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Children’s Hospital Los Angeles has launched a new clinical trial to investigate a potential treatment for Dup15q syndrome, a rare genetic condition that causes developmental delays, autism spectrum disorder and epilepsy.

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In a proof-of-concept in ACS’ Nano Letters, a team has designed injectable nanoparticles that released naloxone ― which rapidly reverses opioid overdose effects ― when triggered by blue light. In experiments with mice, this system was activated a month after injection.

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New research in the November 2023 issue of JNCCN—Journal of the National Comprehensive Cancer Network suggests that breast cancer patients who have insufficient levels of vitamin D before starting paclitaxel treatment are more likely to experience peripheral neuropathy.

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SOPHiA GENETICS (Nasdaq: SOPH), a cloud-native software company and a leader in data-driven medicine, today announced that BioReference® Health, LLC, an OPKO Health, Inc. company and full-service laboratory that processes more than 12 million tests annually, will implement SOPHiA GENETICS' technology and add MSK-ACCESS® liquid biopsy to its test suite.

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MD Anderson and Jazz Pharmaceuticals announced a five-year strategic research collaboration agreement to evaluate zanidatamab, Jazz’s investigational HER2-targeted bispecific antibody, in multiple HER2-expressing cancers.

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Value in Health announced the publication of a study showing that United States Medicare could save up to an additional $5-$10 billion dollars annually across 10 drugs if it negotiated prices using a therapeutic reference pricing approach rather than using the statutory ceiling price alone.

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A new targeted drug, studied by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James), may offer a new treatment option for patients with blood cancers, including chronic lymphocytic leukemia and Non-Hodgkin lymphoma whose disease has stopped responding to standard treatments.

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Researchers combined the features of clinical drugs to treat hepatitis C and viruses similar to COVID-19. This allowed them to synthesize BBH-1, a promising inhibitor that targets the breakdown of the SARS-CoV-2 virus. The researchers characterized samples using X-ray and neutron diffraction techniques to provide atomic-level insights on the structure of the BBH-1 inhibitor and how it binds to the SARS-CoV-2 protein.

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Cancer drug could treat inflammatory diseases by calming down the inflammatory response

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In an invited commentary, Kathleen Mulvaney, assistant professor with the Fralin Biomedical Research Institute at VTC, talks about the potential of a new drug that has shown early promise in clinical trials for solid tumors by killing cancer cells that lack specific tumor suppressor genes.

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An international research team, including Jonathan C. Schisler, PhD, in the UNC School of Medicine, has found how SARS-CoV-2 causes widespread “energy outages” throughout major organs, and how these effects contribute to debilitating long COVID symptoms.

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A new drug developed by professors from the School of Pharmacy and Pharmaceutical Sciences at Binghamton University, State University of New York has received FDA approval for the treatment of patients with Duchenne muscular dystrophy, a common genetic disease that mostly affects young boys.

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Joseph A. Barone, Dean of the Rutgers University Ernest Mario School of Pharmacy, has been selected as the 2023 recipient of the New Jersey Pharmacists Association Lifetime Achievement Award

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In August 2022, a New York Times article highlighted an off-label use of a drug that remedies a type of hair loss. The subsequent media attention led to a surge in interest in the drug known as Minoxidil. Researchers at the George Washington University surveyed pharmacies in the Washington, Maryland and Virginia metro area and found shortages in thirty day supplies of the drug.

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UC San Diego engineers have developed modular nanoparticles that can be easily customized to target different biological entities such as tumors, viruses or toxins. The surface of the nanoparticles is engineered to host any biological molecules of choice, making it possible to tailor the nanoparticles for a wide array of applications, ranging from targeted drug delivery to neutralizing biological agents.