A new study from Washington University School of Medicine in St. Louis has uncovered a previously unknown role for exosomes in inflammatory respiratory diseases. The study has implications for finding new therapies. Exosomes are tiny compartments released from cells that carry different types of cargo, including inflammatory chemicals called cytokines that can drive lung disease.
ROCKVILLE, MD – A tenth of all intensive care unit patients worldwide, and many critical patients with COVID-19, have acute respiratory distress syndrome (ARDS).
In a long-term study in a Salt Lake-area building, researchers found that the amount of air pollution that comes indoors depends on the type of outdoor pollution. Wildfires, fireworks and wintertime inversions all affect indoor air to different degrees.
Around 80% of the UK population is currently infected with human cytomegalovirus (HCMV) and in developing countries this can be as high as 95%.
To mark Rare Disease Day on February 28, the Pulmonary Fibrosis Foundation (PFF) aims to increase public understanding of pulmonary fibrosis (PF) to drive home the importance of early diagnosis to help improve the quality of life for patients.
The ATS 2021 International Conference is May 14-19 this year. We’re virtual and, therefore, available anywhere you are. Our featured speaker is Dr. Anthony Fauci, who will present at the opening ceremony on Saturday, May 15.
Masks help protect the people wearing them from getting or spreading SARS-CoV-2, the virus that causes COVID-19, but now researchers from the National Institutes of Health have added evidence for yet another potential benefit for wearers: The humidity created inside the mask may help combat respiratory diseases such as COVID-19.
Researchers at the Southwest National Primate Research Center (SNPRC) at Texas Biomedical Research Institute (Texas Biomed) may have found a new pathway to treat and control tuberculosis (TB), the disease caused by Mycobacterium tuberculosis (Mtb). Using single-cell RNA sequencing (scRNAseq), a next-generation sequencing technology, scientists were able to further define the mechanisms that lead to TB infection and latency.
Jefferson researchers join a CDC study to follow COVID-19 “long-haulers” and their symptoms.
New research shows chocolate-flavored e-cigarettes are “particularly harmful” to the lungs.
UC San Diego researchers find that an optical tool already embedded in many smartphones can accurately diagnose blood-oxygen levels and help monitor respiratory disease in patients, particularly when they are quarantined at home.
Experts discuss key insights in clinical treatment of COVID-19 from Year One of the pandemic.
A study published today in the New England Journal of Medicine provides the most definitive evidence to date that, of the two drugs recommended for light sedation of patients receiving mechanical ventilation in the ICU, one is as effective and safe as the other.
Recently awarded two APEX Recognition Awards, respiratory therapists at Rush are advancing COVID-19 treatment.
NIH researchers and their collaborators found that inhaling unfragmented hyaluronan improves lung function in patients suffering from severe exacerbation of COPD. Hyaluronan is a sugar secreted by living tissue that acts as a scaffold for cells. Utilized as a treatment, hyaluronan decreased the number of days in the hospital.
The finding can offer a new way for creating therapies to prevent secondary bacterial infections.
Research from the University of Georgia shows that state laws promoting flu vaccinations for hospital workers can substantially reduce the number of influenza-related deaths.
According to the Surgeon General, 14% of Americans smoke and 16 million suffer from smoking-related diseases. Pulmonary fibrosis, a debilitating disease often caused by tobacco usage, is little-known among smokers. The Pulmonary Fibrosis Foundation shares insights on critical risk factors.
Researchers at Canada's McMaster University have established in lab settings that a novel combination of two forms of immunotherapy can be highly effective for treating lung cancer, which causes more deaths than any other form of cancer.
Study finds NAD+ break down leads to multi organ scarring, providing now a previously undiscovered pathogenic role of the enzyme CD38 in disease scarring.
E-cigarette exposure stresses and inflames the lungs of rats, compromising important quality control proteins, according to new research.
COVID-19 deaths are indeed different from other lung failure deaths, according to two recent studies, with 56% of COVID-19 patients dying primarily from the lung damage caused by the virus, compared with 22% of those whose lungs fail due to other causes. But, the researchers conclude, the kind of care needed to help sustain people through the worst cases of all forms of lung failure is highly similar, and just needs to be fine-tuned.
Researchers have developed a DNA test to quickly identify secondary infections in COVID-19 patients, who have double the risk of developing pneumonia while on ventilation than non-COVID-19 patients.
The Pulmonary Fibrosis Foundation (PFF) has announced United Therapeutics' sponsorship of the PFF Registry, a research resource that tracks clinical data, blood samples and patient-reported outcomes from individuals living with pulmonary fibrosis nationwide.
A new study analyzes the potential transmission risk of airborne respiratory pathogens during bystander-initiated cardiopulmonary resuscitation, or CPR.
There is more evidence that vaping causes abnormal lung function in young, otherwise healthy people.
Researchers evaluating whether an investigational oral drug, vadadustat, can help prevent acute respiratory distress syndrome (ARDS) in COVID-19 patients were awarded $5.1 million in funding from the U.S. Department of Defense (DOD) to expand the Phase II clinical trial at UTHealth.
A small and inexpensive sensor, announced in Applied Physics Letters and based on an electrochemical system, could potentially be worn continuously by cardiac patients or others who require constant monitoring. A solution containing electrolyte substances is placed into a small circular cavity that is capped with a thin flexible diaphragm, allowing detection of subtle movements when placed on a patient’s chest. The authors suggest their sensor could be used for diagnosis of respiratory diseases.
An unfortunate truth about using mechanical ventilation to save lives is that the pressure can cause further lung damage. Scientists are working to boost a natural cellular process in pursuit of a therapy that could lower the chances for lung damage in patients on ventilators.
Program’s 100th Lung Transplant Is Its First for a Patient with Lungs Damaged by COVID-19
Today, the Pulmonary Fibrosis Foundation (PFF) announced enrollment of the first patient in PRECISIONS (Prospective tReatment EffiCacy in IPF uSIng genOtype for Nac Selection) clinical trial. This is the first clinical trial to apply the principles of precision medicine to the treatment of patients with idiopathic pulmonary fibrosis (IPF).
A new study published online in the Annals of the American Thoracic Society examines the recovery of lung function and overall wellness in individuals who had varying degrees of COVID-19 severity. Little is known about lung health following infection with SARS-CoV-2, the virus that causes COVID-19, and whether later respiratory problems, fatigue and ill health are associated with the disease’s initial severity.
Credentialed press representatives are invited to attend The Society of Thoracic Surgeons VIRTUAL 57th Annual Meeting. This interactive, fully digital experience—expected to be unlike anything that cardiothoracic surgery has experienced to date—will feature thought-provoking lectures, practice-changing science, and cutting-edge techniques and technologies.
DALLAS – Jan. 5, 2021 – Researchers at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have discovered a new metabolic vulnerability in a highly aggressive form of non-small cell lung cancer (NSCLC). These findings could pave the way for new treatments for patients with mutations in two key genes – KRAS and LKB1. Patients whose tumors contain both of these mutations, known as KL tumors, have poor outcomes and usually do not respond to immunotherapy.
Due to COVID-19, it’s important to talk to your doctor right away if you’re experiencing symptoms such as shortness of breath or cough. Take notes about your symptoms, so your doctor can pinpoint if they are early warning signs of another respiratory disease such as pulmonary fibrosis (PF).
In some cases, immune cells in the lungs can contribute to worsening a virus attack. In a new study, researchers at Karolinska Institutet in Sweden describe how different kinds of immune cells, called macrophages, develop in the lungs and which of them may be behind severe lung diseases.
The emergence of Severe Acute Respiratory Syndrome (SARS) in 2003 and Middle East Respiratory Syndrome (MERS) in 2012, caused by SARS-CoVand MERS-CoV, respectively, demonstrated the zoonotic potential of coronaviruses.
Substances present in cooked meats are associated with increased wheezing in children
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every other Tuesday.
Elizabeth Silva, 47, is more grateful than ever to spend the holidays with her family this year – just a few months ago she couldn’t move or speak after spending weeks in an intensive care unit (ICU) battling COVID-19. “I really didn’t know if I was going to survive,” Silva said. “The virus took everything from me, mentally and physically. Doctors and physical therapists had to teach me to get up, walk, shower, and even brush my hair.”
Reporting on how deferred care worsened outcomes for lung cancer patients when the COVID-19 pandemic first surged in the spring of 2020, researchers from the University of Cincinnati explained that they have identified a framework that could help people with serious health conditions keep up their appointments during the current surge. The study has been selected for the 2020 Southern Surgical Association Program and published as an “article in press” on the Journal of the American College of Surgeons website in advance of print.
By studying the roles of an inflammatory protein and antibodies in chronic rejection after lung transplantation, researchers discover possibilities for new treatments.
What does SARS-CoV-2, the virus that causes COVID-19, do once it enters a person's airways, and how does infection in lung cells affect patients' immune responses? New research led by investigators at Massachusetts General Hospital (MGH) and published in Nature Communications provides insights that could help improve treatment strategies for infected patients.
Almost a year ago, COVID-19 began its global rampage, going on to infect about 69.5 million people and kill about 1.6 million as of early this month. From the beginning, most scientists have said that COVID-19 is deadlier than the seasonal flu, while fringe theories have circulated widely, suggesting it is less deadly or flu’s equal. Evidence is accumulating, however, to show just how much deadlier COVID-19 is compared with the flu and the extent of complications related to the two illnesses.
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