Feature Channels: Stem Cells

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Newswise: The ethics of research on conscious artificial brains
Released: 12-Apr-2022 3:25 PM EDT
The ethics of research on conscious artificial brains
 Kyoto University

One way in which scientists are studying how the human body grows and ages is by creating artificial organs in the laboratory.

Comment
Released: 12-Apr-2022 12:00 PM EDT
Paeoniflorin drives immunomodulation of mesenchymal stem cells via regulating Th1/Th2 cytokines in oral lichen planus
 Preprints

Zhihui Zhang, Yan Zhang, Zhongfang Zhao, Pei Li, Danyang Chen, Wei Wang, Ying Han, Shiqi Zou, Xin Jin, Jianling Zhao, Hongwei Liu, Xiao Wang, Weili Zhu

Comment
Released: 12-Apr-2022 12:00 PM EDT
Exploring Health Behaviors and the Feasibility of a Lifestyle Intervention for Patients with Multiple Myeloma
 Preprints

Allen Hodge, Patricia Sheean, Paula O’Connor, Kiley Tyler, Abigail Kerschner, Alexis Williams, Kathleen Jensik, Alexis Visotcky, Anita D’Souza, Parameswaran Hari, Binod Dhakal, Saurabh Chhabra, Kathryn E. Flynn, Patrick Hagen, Melinda Stolley

Comment
Released: 12-Apr-2022 4:00 AM EDT
Strategies of pluripotent stem cell-based therapy for retinal degeneration: update and challenges
 Trends in Molecular Medicine

Stem cell-based therapy for retinal degeneration is transitioning from the research stage to the clinical stage and is being developed as a treatment across the globe. In clinical studies on induced pluripotent stem cell (iPSC)-… of stem cell-based therapy …

Comment
Released: 12-Apr-2022 4:00 AM EDT
Impact of the multiscale viscoelasticity of Quasi-2D self-assembled protein networks on stem cell expansion at liquid interfaces
 Biomaterials

… and cell types and correlate interfacial mechanical properties with stem cell expansion. Correlations suggest an impact of … stem cell proliferation, we determined the interfacial shear moduli of corresponding interfaces and correlated …

Comment
Released: 11-Apr-2022 12:00 PM EDT
A combination of Granulocyte-macrophage colony-stimulating factor with the R2 regimen in elderly high-risk B cell lymphoma maintenance therapy improves survival by modulating natural killer cells
 Preprints

Shunrong Sun, Wulipan Fulati, Lin Shen, Min Wu, Zilan Huang, Wensi Qian, Pingping Chen, Yingwei Hu, Mingyue Chen, Yu Xu, Hongdi Zhang, Jiexian Ma, Yanhui Xie

Comment
Released: 11-Apr-2022 12:00 PM EDT
Placental mesenchymal stem cells improve ovarian function in a rat model of premature ovarian insufficiency by inhibiting NLRP3 inflammasome activity
 Preprints

Huiming Ma, Na Hu, Shasha Xing, Shudan Liu, Songlin Guo, Feiyan Zhang, Xiaona Ma, Xueyun Liang, Dongmei Chen

Comment
Released: 11-Apr-2022 12:00 PM EDT
A phenotypic screen of Marfan syndrome iPSC-derived vascular smooth muscle cells uncovers GSK3β as a new target
 Preprints

Hongorzul Davaapil, Madeline McNamara, Alessandra Granata, Robyn G. C. Macrae, Mei Hirano, Martina Fitzek, Jose Antonio Aragon-Martin, Anne Child, David M. Smith, Sanjay Sinha

Comment
Released: 11-Apr-2022 12:00 PM EDT
Bone marrow mesenchymal stem cells protect against radiation-induced lung injury by regulating AngII/ACE2/Ang(1-7) axis
 Preprints

Shiying Niu, Changsheng Cong, Zhaopeng Wang, Meili Sun, Yueying Zhang

Comment
Released: 10-Apr-2022 12:00 PM EDT
Autophagic state prospectively identifies facultative stem cells in the intestinal epithelium
 Preprints

Nicolette M Johnson, Louis R Parham, Jeeyoon Na, Keara E Monaghan, Hannah M Kolev, Alena Klochkova, Melissa S Kim, Charles H Danan, Zvi Cramer, Lauren A Simon, Kaitlyn E Naughton, Stephanie Adams-Tzivelekidis, Yuhua Tian, Patrick A Williams, Nicolae A Leu, Simone Sidoli, Kelly A Whelan, Ning Li, Christopher J Lengner, Kathryn E Hamilton

Comment
Released: 10-Apr-2022 12:00 PM EDT
Less is more - loss of EGFL7 improves memory by upregulation of VEGF-D
 Preprints

Mirko Hh Schmidt, Verica Vasic, Kathrin Barth, Frank Bicker, Ulrike Schumann, Christine Maurer, Nora Heinig, Cora Roehlecke, Ute Nimtschke, Lana Schumann, Matthias Meinhardt, Thomas Mittmann, Konstantin Radyushkin, Jan Baumgart, Stefan Tenzer, Frauke Zipp, Irmgard Tegeder

Comment
7-Apr-2022 12:00 PM EDT
NK Cells Combined with Bispecific Antibody Showed Strong Response for Patients with Lymphoma
 University of Texas MD Anderson Cancer Center

Researchers from The University of Texas MD Anderson Cancer Center showed that natural killer (NK) cells derived from donated umbilical cord blood, combined with a novel bispecific antibody known as AFM13 that targets CD16A and CD30, achieved effective responses in patients with pretreated and refractory CD30+ lymphoma. The study was presented today at the American Association for Cancer Research (AACR) Annual Meeting 2022.

Comment
Released: 9-Apr-2022 12:00 PM EDT
Probing Notch1-Dll4 Signaling in Regulating Osteogenic Differentiation of Human Mesenchymal Stem Cells using Single Cell Nanobiosensor
 Preprints

Shue Wang, Yuwen Zhao, Rui Yang, Zoe Bousraou, Kiarra Richardson

Comment
Released: 9-Apr-2022 12:00 PM EDT
Mouse brain-wide transgene expression by systemic injection of genetically engineered exosomes: CAP-Exosomes
 Preprints

James W Simpkins, Deborah Corbin, Saumuendra N Sarkar

Comment
Released: 9-Apr-2022 12:00 PM EDT
How to Heal the Gut’s Brain: Regeneration of the Enteric Nervous System
 Preprints

The neural-crest derived enteric nervous system (ENS) is the intrinsic nervous system of the gastrointestinal (GI) tract and controls all gut functions, including motility.

Comment
Released: 8-Apr-2022 12:00 PM EDT
LncRNA KCNQ10T1 shuttled by bone marrow mesenchymal stem cells-derived exosome inhibits sepsis via regulation of miR-154-3p/RNF19A axis
 Preprints

Haojie Yuan, Junbo Yu, Chun Liu, Jiajia Liu, Jianhua Xue, Heyan Zhao, Yang Yang

Comment
Released: 8-Apr-2022 12:00 PM EDT
Prostaglandins and calprotectin are genetically and functionally linked to the Inflammatory Bowel Diseases
 Preprints

Mohamad Karaky, Gabrielle Boucher, Saraï Mola, Sylvain Foisy, Claudine Beauchamp, Marie-Eve Rivard, Melanie Burnette, Hugues Gosselin, iGenoMed Consortium, Alain Bitton, Guy Charron, Philippe Goyette, John D. Rioux

Comment
Released: 8-Apr-2022 12:00 PM EDT
Divergent MEK/ERK and AMPK signaling dictate lipogenic plasticity and dependence on fatty acid synthesis in Glioblastoma
 Preprints

Christian E. Badr, Katharina Eyme, Alessandro Sammarco, Roshani Jha, Hayk Mnatsakanyan, Rudolph Neustadt, Charlotte Moses, Ahmad Alnasser, Daniel Tardiff, Baolong Su, Kevin Williams, Steven Bensinger, Chee Yeun Chung

Comment
Released: 8-Apr-2022 12:00 PM EDT
Development of an improved inhibitor of Lats kinases to promote regeneration of mammalian organs
 Preprints

Nathaniel R. Kastan, Sanyukta Oak, Rui Liang, Leigh Baxt, Robert W. Myers, John Ginn, Nigel Liverton, David J. Huggins, John Pichardo, Matthew Paul, Thomas S. Carroll, Aaron Nagiel, Ksenia Gnedeva, A. J. Hudspeth

Comment
Released: 8-Apr-2022 12:00 PM EDT
CryoET Reveals Organelle Phenotypes in Huntington Disease Patient iPSC-Derived and Mouse Primary Neurons
 Preprints

Wah Chiu, Gong-Her Wu, Jesús Galaz-Montoya, Michael Schmid, Lydia Joubert, Patrick Mitchell, Cristina Danita, Serena Yeung, Sanket Gupte, Joy Hsu, Judith Frydman, Ranen Aviner, William Mobley, Chengbiao Wu, Yingli Gu, Charlene Smith-Geater, Leslie Thompson, Ricardo Miramontes, Keona Wang, Nicolette Geller

Comment
Released: 8-Apr-2022 12:00 PM EDT
Hippo Signaling Pathway Activation during SARS-CoV-2 Infection Contributes to Host Antiviral Response
 Preprints

Gustavo Garcia, Yijie Wang, Joseph Ignatius Irudayam, Arjit Vijey Jeyachandran, Sebastian Castillo Cario, Chandani Sen, Shen Li, Yunfeng Li, Ashok Kumar, Karin Nielsen-Saines, Samuel W. French, Priya S. Shah, Kouki Morizono, Brigitte Gomperts, Arjun Deb, Arunachalam Ramaiah, Vaithilingaraja Arumugaswami

Comment
Released: 8-Apr-2022 12:00 PM EDT
A method for stabilising the XX karyotype in female mESC cultures
 Preprints

Andrew Keniry, Natasha Jansz, Peter F Hickey, Kelsey Breslin, Megan Iminitoff, Tamara Beck, Matthew E Ritchie, Marnie E Blewitt

Comment
Released: 8-Apr-2022 12:00 PM EDT
Rapid Recovery of Male Cats with Postrenal Acute Kidney Injury by Treating with Allogeneic Adipose Mesenchymal Stem Cell-derived Exosomes
 Preprints

Weihui Li, Wei Wang, Xin He, Zheng Liao, Aili Aierken, Jinlian Hua, Yan Wang, Dezhang Lu, Shiqiang Zhang

Comment
Released: 8-Apr-2022 12:00 PM EDT
Chemical conversion of human conventional Pluripotent Stem Cells to Trophoblast Stem Cells
 Preprints

Irene Zorzan, Riccardo Massimiliano Betto, Giada Rossignoli, Mattia Arboit, Andrea Drusin, Paolo Martini, Graziano Martello

Comment
Released: 8-Apr-2022 12:00 PM EDT
Inhibition of mutant IDH1 promotes cycling of acute myeloid leukemia stem cells
 Preprints

Emily Gruber, Joan So, Alexander C Lewis, Rheana Franich, Rachel Cole, Luciano G Martelotto, Amy J Rogers, Eva Vidacs, Peter Fraser, Kym Stanley, Lisa Jones, Anna S Trigos, Niko Thio, Jason Li, Brandon Nicolay, Scott Daigle, Adriana E Tron, Marc L Hyer, Jake Shortt, Ricky W Johnstone, Lev M Kats

Comment
Released: 8-Apr-2022 12:00 PM EDT
Single Ion Channel Recording in 3D Culture of Stem Cells Using Patch-Clamp Technique
 Preprints

Vladislav I. Chubinskiy-Nadezhdin, Anastasia V. Sudarikova, Mariia A. Shorokhova, Valeria Y. Vasileva, Zuleikha M. Khairullina, Yuri A. Negulyaev

Comment
Released: 8-Apr-2022 12:00 PM EDT
A novel nitidine chloride nanoparticle overcomes the stemness of CD133 + EPCAM + Huh7 Hepatocellular Carcinoma Cells for liver cancer therapy
 Preprints

Danni Li, Qiying Zhang, Yuzhu Zhou, Hua Zhu, Tong Li, Fangkai Du

Comment
Released: 8-Apr-2022 12:00 PM EDT
A Comprehensive Roadmap of Human Placental Development in vitro
 Preprints

Jaroslav Slamecka, Carlos A. Tristan, Seumgmi Ryu, Pei-Hsuan Chu, Claire Weber, Tao Deng, Yeliz Gedik, Pinar Ormanoglu, Sam Michael, Ty C. Voss, Anton Simeonov, İlyas Singec

Comment
Released: 7-Apr-2022 12:00 PM EDT
Impact of Genetic Diagnosis on the Outcome of Hematopoietic Stem Cell Transplant in Primary Immunodeficiency Disorders
 Preprints

Federica Forlanini, Alice Chan, Jasmeen Dara, Christopher C. Dvorak, Morton J. Cowan, Jennifer M. Puck, Morna J. Dorsey

Comment
Released: 7-Apr-2022 12:00 PM EDT
Association between cancer stem cell gene signature and prognosis in head and neck squamous cell carcinoma
 Preprints

Su Il Kim, Seon Rang Woo, Joo Kyung Noh, Min Kyeong Lee, Young Chan Lee, Jung Woo Lee, Moonkyoo Kong, Seong-Gyu Ko, Young-Gyu Eun

Comment
Released: 7-Apr-2022 12:00 PM EDT
GATA2 as an outcome signature: promoting bladder cancer migration and inhibiting PD-L1 expression
 Preprints

Siqing Sun, Jianbin Bi

Comment
Released: 7-Apr-2022 12:00 PM EDT
Hematopoietic stem cell-derived fibrocytes as targets and tools for cancer therapy: mechanisms and therapeutic implications
 Preprints

Liyi Zhang, Haibo Qiu, Xu Zhang, Jiali Qi, Jiangwen Zhang, Yin Tong, Lei Li, Li Fu, Yan-Ru Qin, Xinyuan Guan

Comment
Released: 7-Apr-2022 11:05 AM EDT
UC San Diego Studying Cells in Space for Early Cancer Detection
 UC San Diego Health

Comment
5-Apr-2022 10:05 AM EDT
Mount Sinai Develops Method to Advance Maturation of Human Pluripotent Stem Cell-Derived Heart Cells
 Mount Sinai Health System

New study outlines scalable protocol to enhance development and understanding of human pluripotent stem cells in cardiac muscles

Comment
Released: 6-Apr-2022 4:20 PM EDT
Turmeric compound helps grow engineered blood vessels and tissues
 University of California, Riverside

A finding by UC Riverside bioengineers could hasten development of lab-grown blood vessels and other tissues to replace and regenerate damaged tissues in human patients.

Comment
Released: 6-Apr-2022 12:00 PM EDT
Production and preservation of serum-free human umbilical cord-derived mesenchymal stem cell sheets
 Preprints

Juan Wang, Shuang Gao, Yufei Zhao, TaiBing Fan, Mingkui Zhang, Dehua Chang

Comment
Released: 6-Apr-2022 12:00 PM EDT
JAK/STAT3 Pathway Promotes Proliferation of Ovarian Aggregate-derived Stem Cells in vitro
 Preprints

Maryam Saber, Faezeh Shekari, Seyed-Ahmad Mousavi, Ashraf Moini, Monireh-Sadat Miri, Fereshteh Esfandiari

Comment
Released: 6-Apr-2022 12:00 PM EDT
Effect of Human Platelet Lysate as Cultivation Nutrient Supplement on the Expansion of Human Natal Dental Pulp Stem Cells In Vitro
 Preprints

Nela Pilbauerova, Jan Schmidt, Tereza Suchankova Kleplova, Tomas Soukup, Jakub Suchanek

Comment
Released: 6-Apr-2022 12:00 PM EDT
Targeting senescent cells by dasatinib and quercetin ameliorates postmenopausal osteoporosis and rejuvenates bone regeneration.
 Preprints

Ying Wang, Linbin Che, Xi Chen, Zirui He, Dianwen Song, Yuan Yuan, Changsheng Liu

Comment
Released: 5-Apr-2022 12:00 PM EDT
Translational development of ABCB5+ dermal mesenchymal stem cells for therapeutic induction of angiogenesis in non-healing diabetic foot ulcers
 Preprints

Mark Andreas Kluth, Andreas Kerstan, Kathrin Dieter, Elke Niebergall-Roth, Sabrina Klingele, Michael Jünger, Christoph Hasslacher, Georg Daeschlein, Lutz Stemler, Ulrich Meyer-Pannwitt, Kristin Schubert, Gerhard Klausmann, Titus Raab, Matthias Goebeler, Korinna Kraft, Jasmina Esterlechner, Hannes M. Schröder, Samar Sadeghi, Seda Ballikaya, Martin Gasser, Ana M. Waaga-Gasser, George F. Murphy, Dennis P. Orgill, Natasha Y. Frank, Christoph Ganss, Karin Scharffetter-Kochanek, Markus H. Frank

Comment
Released: 5-Apr-2022 12:00 PM EDT
Low-intensity pulsed ultrasound/nanomechanical force generators enhance osteogenesis of bone marrow mesenchymal stem cells through microfilaments and transient receptor potential melastatin 7 activation
 Preprints

Huan Yao, Liang Zhang, Shujin Yan, Yiman He, Hui Zhu, Yasha Li, Ke Yang, Dong Wang

Comment
Released: 5-Apr-2022 12:00 PM EDT
PDIA3P1 Promotes Temozolomide Resistance in Glioblastoma by Inhibiting C/EBPβ Degradation to Facilitate Proneural-to- Mesenchymal Transition
 Preprints

Zijie Gao, Jianye Xu, Yang Fan, Yanhua Qi, Shaobo Wang, Shulin Zhao, Xing Guo, Hao Xue, Lin Deng, Rongrong Zhao, Chong Sun, Ping Zhang, Gang Li

Comment
Released: 5-Apr-2022 12:00 PM EDT
Breast cancer stem cell-derived tumors escape from γδ T cell immunosurveillance in vivo by modulating γδ T cell ligands
 Preprints

Katrin Raute, Juliane Strietz, Geoffroy Andrieux, Oliver S. Thomas, Klaus Maximilian Kistner, Marina Zintchenko, Peter Aichele, Houjiang Zhou, Wilfried Weber, Melanie Boerries, Mahima Swamy, Jochen Maurer, Susana Minguet

Comment
Released: 5-Apr-2022 12:00 PM EDT
Engineering Proprioceptive Implants via Surgical and Regenerative Approaches: Preliminary Interpretations
 Preprints

Siddhartha Das, Haladhar Dev Sarma, Jayesh Bellare

Comment
Released: 5-Apr-2022 12:00 PM EDT
Machine Learning Classification Reveals Robust Morphometric Biomarker of Glial and Neuronal Arbors
 Preprints

Masood A Akram, Qi Wei, Giorgio Ascoli

Comment
Released: 5-Apr-2022 12:00 PM EDT
Nuclear inhibitor of protein phosphatase 1 (NIPP1) regulates CNS tau phosphorylation and myelination during development
 Preprints

Cody McKee, Peter Shrager, Arindam Mazumder, Archan Ganguly, Abigail Mayer, Karl Foley, Nancy Ward, Margaret Youngman, Mathieu Bollen, Hailong Hou, Houhui Xia

Comment
Released: 5-Apr-2022 12:00 PM EDT
Investigating the Role Of CRISPR In Treating Hematopoietic Malignancies
 Preprints

Diya Tibrewal

Comment
Released: 5-Apr-2022 12:00 PM EDT
Transcriptional Heterogeneity and Cell Cycle Regulation as Central Determinants of Primitive Endoderm Priming
 Preprints

Joshua M Brickman, Marta Perera, Silas Boye Nissen, Martin Proks, Sara Pozzi, Rita Soares Monteiro, Ala Trusina

Comment
Released: 5-Apr-2022 12:00 PM EDT
Tissue-wide Genetic and Cellular Landscape Shapes the Execution of Sequential PRC2 Functions in Neural Stem Cell Lineage Progression
 Preprints

Nicole Amberg, Florian M Pauler, Carmen Streicher, Simon Hippenmeyer

Comment
Released: 5-Apr-2022 12:00 PM EDT
Mesenchymal Stem Cells Modified with Angiotensin Converting Enzyme 2 are Superior in Ameliorating Inflammation and Oxidative Stress in Diabetic Nephropathy
 Preprints

Shasha Lv, Shanshan Liu, Yun Sun, Jing Cheng, Fulin Dou, Qiaoying Xu, Yinghui Wang, Qingzhen Liu, Gang Liu

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