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When flu season peaks after mid-winter, tens of thousands of influenza cases and hundreds of deaths can likely be avoided if older adults wait until October to get their flu immunization, a University of Pittsburgh School of Medicine analysis reveals.

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An annual influenza season forecasting challenge issued by the US Centers for Disease Control provides unique insight into epidemic forecasting, according to a study published in the journal Scientific Reports.

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A monthly roundup of research briefs showcasing recent scientific advances led by Beth Israel Deaconess Medical Center faculty.

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Sharon Wright, MD, MPH, BIDMC’s Director of Infection Control/Hospital Epidemiology, shares everything you need to know about the flu – from how to prepare before you get sick and when to call a doctor.

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The Centers for Disease Control reports that influenza activity in Alabama is now widespread and likely to increase. Alabama’s Department of Public Health also reports that almost every Alabama county is experiencing significant flu activity. As Alabama and the rest of the country enter the height of flu season, University of Alabama at Birmingham medical caregivers want to remind the public that, if you are normally a healthy person who is experiencing flu-like symptoms — high fever, muscle or body aches throughout the body, exhaustion, and loss of appetite — do not go to the emergency department.

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Researchers from the National Institutes of Health have discovered that antibodies that may form the basis of a universal flu vaccine inhibit a second viral protein in addition to the one that they bind. The study, to be published January 25 in the Journal of Experimental Medicine, reveals that antibodies that recognize the viral surface protein hemagglutinin can also inhibit the viral neuraminidase, and that this enhances antibody neutralization of the virus and the activation of innate immune cells with anti-viral activity.

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• Influenza-like illness was linked with seasonal variation in the death rates of US patients with kidney failure.

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Arnold Monto, professor of epidemiology at the University of Michigan School of Public Health, has been studying the spread of the flu virus and the effectiveness of vaccines and antiviral medications for more than five decades.