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Newswise: Case Western Reserve receives NIH funding to study long-term health effects of East Palestine, Ohio, train derailment
Released: 27-Feb-2024 9:00 AM EST
Case Western Reserve receives NIH funding to study long-term health effects of East Palestine, Ohio, train derailment
Case Western Reserve University

The National Institutes of Health (NIH) has awarded researchers at Case Western Reserve University a grant to begin studying the possible long-term health effects of exposure to hazardous chemicals from the East Palestine, Ohio, train derailment.

Released: 26-Feb-2024 10:05 PM EST
Healthcare leaders plea to reinstate the Canadian hypertension control program to prevent death and disability
Elsevier

A passionate plea for the re-establishment of Canada's health coalition focused on hypertension prevention and control appears as an editorial in the Canadian Journal of Cardiology, published by Elsevier.

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Released: 26-Feb-2024 7:05 PM EST
Study Details How a Common Bacterium Resists New Antibiotic
Cedars-Sinai

Cedars-Sinai investigators have detailed a new way that bacteria use iron to cooperate and resist antibiotic treatment. The study, led by the Cedars-Sinai departments of Biomedical Sciences and Pathology and Laboratory Medicine, is published in the peer-reviewed journal Nature Microbiology and is the first to show this type of antibiotic cross-protection.

Released: 26-Feb-2024 12:00 PM EST
Advances in the differentiation of pluripotent stem cells into vascular cells
World Journal of Stem Cells

Blood vessels constitute a closed pipe system distributed throughout the body, transporting blood from the heart to other organs and delivering metabolic waste products back to the lungs and kidneys. Changes in blood vessels are related to

Released: 26-Feb-2024 12:00 PM EST
Effects of different concentrations of nicotinamide on hematopoietic stem cells cultured in vitro
World Journal of Stem Cells

BACKGROUNDIn vitro expansion to increase numbers of hematopoietic stem cells (HSCs) in cord blood could improve clinical efficacy of this vital resource. Nicotinamide (NAM) can promote HSC expansion ex vivo, but its effect on hematopoietic

23-Feb-2024 3:05 PM EST
Shifting focus: Investigators describe changes to pancreatic β cell at onset of Type 1 Diabetes
Joslin Diabetes Center

About eight million people live with Type 1 diabetes (T1D) worldwide, a chronic autoimmune condition in which the body attacks and destroys its own insulin-producing β-cells (pronounced “beta”) in the pancreas, leading to a lack of insulin and inability to regulate blood sugar. It’s not known why the body suddenly perceives its own β-cells as the enemy; some lines of evidence suggest environmental factors such as viral infections may trigger the onset of T1D, others suggest genetics may also play some role. Groundbreaking research by investigators at Joslin Diabetes Center sheds new light on the specific changes β-cells go through at the onset of T1D. Their findings—published in Nature Cell Biology—offer new avenues for targeted interventions for the chronic autoimmune condition.

Released: 23-Feb-2024 8:05 PM EST
Researchers explore whether gut microbes cause some COVID-19 patients to have higher blood clot risk
Cell Press

A gut microbial metabolite called 2-methylbutyrylcarnitine (2MBC) plays a role in exacerbating thrombosis -- the formation of blood clots – researchers report February 23rd in the journal Cell Metabolism.

Newswise: An increase in blood-sucking black flies is expected in Germany
Released: 23-Feb-2024 11:05 AM EST
An increase in blood-sucking black flies is expected in Germany
Goethe-Universität Frankfurt am Main

Only six millimeters in length, black flies (Simuliidae) may look harmless like house flies, but their bites can be very unpleasant.

   
Released: 23-Feb-2024 11:05 AM EST
Genes affect your blood pressure from early childhood
Norwegian University of Science and Technology (NTNU)

Certain genes associated with hypertension affect blood pressure from early in life, and they increase the risk of cardiovascular disease as you get older. However, you can do something about it.

19-Feb-2024 9:05 AM EST
Long COVID linked to persistently high levels of inflammatory protein: a potential biomarker and target for treatments
University of Cambridge

SARS-CoV-2 triggers the production of the antiviral protein IFN-γ, which is associated with fatigue, muscle ache and depression. New research shows that in Long COVID patients, IFN-y production persists until symptoms improve, highlighting a potential biomarker and a target for therapies.

Newswise: Detecting Pathogens--and Sepsis--Faster and More Accurately by Melting DNA
20-Feb-2024 9:05 PM EST
Detecting Pathogens--and Sepsis--Faster and More Accurately by Melting DNA
University of California San Diego

A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, which are the current state of the art for infection diagnosis. The new method, called digital DNA melting analysis, can produce results in under six hours, whereas culture typically requires 15 hours to several days, depending on the pathogen.

Released: 20-Feb-2024 4:05 PM EST
New cell-based immunotherapy offered for melanoma
Washington University in St. Louis

Siteman Cancer Center, based at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis, is one of the first centers nationwide to offer a newly approved cell-based immunotherapy that targets melanoma.

Released: 19-Feb-2024 3:05 PM EST
Moffitt Plays Pivotal Role in FDA Approval of Tumor-Infiltrating Lymphocyte Therapy for Advanced Melanoma
Moffitt Cancer Center

A first-of-its-kind cellular immunotherapy pioneered at Moffitt Cancer Center has received approval from the Food and Drug Administration and is now available for patients with advanced melanoma. Lifileucel is the first tumor-infiltrating lymphocyte therapy, or TIL, approved for solid tumors.

Newswise: New technology brings advanced blood imaging closer to the clinic
Released: 16-Feb-2024 10:05 AM EST
New technology brings advanced blood imaging closer to the clinic
National Institute of Biomedical Imaging and Bioengineering

The qualities of flowing blood, or hemodynamics, hold important insights into vascular diseases, but technological limitations have largely kept measurements of these properties out of reach in the clinic. Now, there may be a potential solution on the horizon.

Released: 15-Feb-2024 8:10 AM EST
Study reports drinking 100% orange juice results in lower daily blood glucose compared to sugar-sweetened, orange-flavored beverages
Florida Department of Citrus

A new study published by Nutrients reports that consuming 100% orange juice prior to a meal, when compared to sugar-sweetened, orange-flavored drinks, suppresses food intake at the next meal and results in lower daily blood glucose concentrations in healthy, normal-weight adults.1

Newswise: Male fertility gene discovery reveals path to success for sperm
Released: 14-Feb-2024 7:05 PM EST
Male fertility gene discovery reveals path to success for sperm
University of Edinburgh

The discovery of a pair of genes that work in perfect harmony to protect male fertility, could provide new insights into some unexplained cases of the most severe form of infertility, research suggests.

Newswise: Researchers Uncover Mechanisms behind Enigmatic Shapes of Nuclei
13-Feb-2024 11:00 AM EST
Researchers Uncover Mechanisms behind Enigmatic Shapes of Nuclei
University of California San Diego

White blood cells known as neutrophils feature a nucleus that is structured strikingly different than most nuclei. These unique shapes permit neutrophils to travel all over the body to combat invading pathogens.

   
Released: 13-Feb-2024 8:05 PM EST
Better diagnosis and treatment of cryptococcosis
University of Cologne

A group of international mycology experts led by Professor Dr Oliver A. Cornely at the University of Cologne has jointly drafted a guideline for the diagnosis and treatment of cryptococcosis, which aims at improving infection management and thus the survival rate of patients.

Released: 13-Feb-2024 11:05 AM EST
Life doesn't stop at age 65. Get the latest on seniors and healthy aging in the Seniors channel
Newswise

Below are some of the latest research and features on this growing population of older adults in the Seniors channel on Newswise.

Newswise: Chula Researcher’s Innovative Wireless Hepatitis B Test Kit for Complete Screening and Data Collection in One Step
Released: 13-Feb-2024 8:55 AM EST
Chula Researcher’s Innovative Wireless Hepatitis B Test Kit for Complete Screening and Data Collection in One Step
Chulalongkorn University

Chula researchers have developed a remarkable wireless hepatitis B virus test kit to screen for infection and collect data for an online database that’s fast and complete in one step.

Newswise: A standard blood test can predict a heart attack
Released: 12-Feb-2024 11:05 PM EST
A standard blood test can predict a heart attack
Uppsala University

Using the results of a standard blood test and an online tool, you can find out if you are at increased risk of having a heart attack within six months.

Released: 12-Feb-2024 11:05 PM EST
Sister cells uncover pre-existing resistant states in cancer
University of Helsinki

Labeling cancer cells with genetic barcodes “In ReSisTrace, we label cancer cells uniquely with genetic barcodes and allow them to divide once, so that we get two identical sister cells that share the same barcode.

Newswise: Novel bispecific design improves CAR T–cell immunotherapy for childhood leukemia
Released: 12-Feb-2024 11:55 AM EST
Novel bispecific design improves CAR T–cell immunotherapy for childhood leukemia
St. Jude Children's Research Hospital

Findings from St. Jude Children’s Research Hospital showed a novel dual targeting approach, where a single molecule can recognize two potential cancer-related proteins, is more effective than the single targeting approach, preventing immune escape.

Newswise: RUDN doctors found a mechanism of preeclampsia development
Released: 12-Feb-2024 7:05 AM EST
RUDN doctors found a mechanism of preeclampsia development
Scientific Project Lomonosov

RUDN University doctors studied immunohistochemical markers in patients with normal pregnancy and preeclampsia and noticed patterns.

Released: 11-Feb-2024 9:05 PM EST
Black women in the US murdered six times more often than White women over last 20 years
Columbia University, Mailman School of Public Health

Black women in the U.S were, on average, six times more likely to be murdered than their white peers for the years 1999 through 2020, according to an analysis of racial disparities in U.S. homicide rates released by Columbia University Irving Medical Center and Columbia’s Mailman School of Public Health.

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5-Feb-2024 8:00 AM EST
3D Ice Printing can Create Artificial Blood Vessels in Engineered Tissue
Biophysical Society

Over 100,000 individuals in the United States are currently in need of organ transplants. The demand for organs, such as hearts, kidneys, and livers, far exceeds the available supply and people sometimes wait years to receive a donated organ.

   
Newswise: International Study Finds Thrombectomy Highly Effective Long-Term Treatment for Large Strokes
9-Feb-2024 9:05 AM EST
International Study Finds Thrombectomy Highly Effective Long-Term Treatment for Large Strokes
University Hospitals Cleveland Medical Center

In a major, international study, named SELECT2, a University Hospitals (UH) research team found that patients with large strokes had a dramatically better recovery after endovascular thrombectomy plus medical management at long-term follow-up, than patients who only received standard medical management.

Newswise: Harnessing Human Evolution to Advance Precision Medicine
Released: 9-Feb-2024 3:05 PM EST
Harnessing Human Evolution to Advance Precision Medicine
University of California San Diego

Scientists hope to advance precision medicine through the discovery of a gene variant that leads to the same phenotype in separate high-dwelling populations while taking a different evolutionary path.

Released: 9-Feb-2024 10:05 AM EST
Moffitt Develops First Individualized Predictive Model for Multiple Myeloma Treatment
Moffitt Cancer Center

In a new article published in the Journal of Clinical Oncology, Moffitt Cancer Center researchers in collaboration with Sylvester Comprehensive Cancer Center and groups around the world share results from a novel model that can provide tailored predictions of how individual patients respond to different therapies.

Released: 8-Feb-2024 5:05 PM EST
Fibroblasts in the penis are more important for erectile function than previously thought
Karolinska Institute

Regular erections could be important for maintaining erectile function, according to a new study on mice published in Science by researchers at Karolinska Institutet.

Released: 8-Feb-2024 3:00 PM EST
Novel Treatment Regimen for FLT3-Mutated Acute Myeloid Leukemia Shows Promise in Roswell Park-Led Study
Roswell Park Comprehensive Cancer Center

Up to 30% of patients newly diagnosed with acute myeloid leukemia (AML) have an FLT3 gene mutation, which is associated with a high risk of relapse and a very poor prognosis.

Newswise: Blood test predicts psychosis risk, most effective treatments
Released: 8-Feb-2024 10:05 AM EST
Blood test predicts psychosis risk, most effective treatments
Indiana University

Team of researchers led by Indiana University School of Medicine faculty have developed a breakthrough new blood test for schizophrenia, a psychiatric disorder that includes hallucinations and delusions.

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Released: 8-Feb-2024 8:55 AM EST
Clues to cancer drug’s deadly side effects could make it safer
University of Illinois Chicago

For some leukemia patients, their only treatment option carries a risk of heart failure

Released: 8-Feb-2024 8:00 AM EST
Unveiling potential diagnostic, treatment target for APS-related thrombocytopenia
Michigan Medicine - University of Michigan

No standard treatment exists for thrombocytopenia in patients with antiphospholipid syndrome, but this could change with a new treatment target

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Released: 7-Feb-2024 11:05 AM EST
RESEARCH ALERT: Stopping Multiple Myeloma
Cedars-Sinai

Cedars-Sinai Cancer investigators have discovered a protein expressed on multiple myeloma cancer cells that drives disease growth and development. The new study found that blocking part of the protein’s unique signaling pathway stops myeloma growth in culture and in laboratory mice.

Newswise: Johns Hopkins Researchers Make Progress Toward Developing Blood Tests for Psychiatric and Neurological Disorders
Released: 7-Feb-2024 10:00 AM EST
Johns Hopkins Researchers Make Progress Toward Developing Blood Tests for Psychiatric and Neurological Disorders
Johns Hopkins Medicine

Researchers in a Johns Hopkins Children’s Center-led study say they have made progress in developing a blood test to identify disease-associated changes in the brain specifically linked to postpartum depression and other psychiatric and neurological disorders.

Released: 6-Feb-2024 10:05 AM EST
AI-powered projects targeting blindness, cervical cancer selected for Penn Medicine accelerator program
Perelman School of Medicine at the University of Pennsylvania

Through the use of artificial intelligence, teams hope to better check for diabetic retinopathy and improve the process of cervical cancer screenings

Released: 6-Feb-2024 9:30 AM EST
Physician Scientists Underrepresented in Medicine to Conduct Health Equity Research at Montefiore and Einstein
Albert Einstein College of Medicine and Montefiore Health System

Montefiore Health System and Albert Einstein College of Medicine have been awarded a $1.5 million National Institutes of Health grant to provide advanced research training to post-graduate trainees from groups that are underrepresented in medicine and have research interests in heart, lung, blood, and sleep disorders. Over five years, nine researchers will receive intense research training and robust mentorship from almost 30 established, senior investigators across Montefiore and Einstein.

Newswise: Awards totaling $2.6 Million Support Exploration of Therapeutic Strategy for Adult and Pediatric T-cell Acute Lymphoblastic Leukemia
Released: 6-Feb-2024 8:05 AM EST
Awards totaling $2.6 Million Support Exploration of Therapeutic Strategy for Adult and Pediatric T-cell Acute Lymphoblastic Leukemia
Rutgers Cancer Institute of New Jersey

Daniel Herranz Benito, PhD, PharmD, resident researcher at Rutgers Cancer Institute of New Jersey, the state’s leading cancer program and only NCI-designated Comprehensive Cancer Center together with RWJBarnabas Health, and associate professor of pharmacology and pediatrics at Rutgers Robert Wood Johnson Medical School, has received a total of $2.6M to support his research on acute lymphoblastic leukemia (ALL), an aggressive type of leukemia that affects both children and adults.

Newswise: Spiky insight: How red blood cells deform
Released: 6-Feb-2024 2:05 AM EST
Spiky insight: How red blood cells deform
Empa, Swiss Federal Laboratories for Materials Science and Technology

Empa researchers have observed living red blood cells transforming into spiky "echinocytes" in real time when treated with high concentrations of ibuprofen using holotomographic microscopy and displayed them in 3D renderings.

Newswise: A rare recent case of retrovirus integration: An infectious gibbon ape leukaemia virus is colonising a rodent’s genome in New Guinea
Released: 5-Feb-2024 10:05 PM EST
A rare recent case of retrovirus integration: An infectious gibbon ape leukaemia virus is colonising a rodent’s genome in New Guinea
Forschungsverbund Berlin e.V.

Retroviruses are viruses that multiply by incorporating their genes into the genome of a host cell. If the infected cell is a germ cell, the retrovirus can then be passed on to the next generation as an “endogenous” retrovirus (ERV) and spread as part of the host genome in that host species.

   
Newswise: Tracking radioactive source recovery: New Cesium Irradiator Replacement Project Dashboard
Released: 5-Feb-2024 9:30 AM EST
Tracking radioactive source recovery: New Cesium Irradiator Replacement Project Dashboard
Idaho National Laboratory (INL)

People often think of radiation as the basis for carbon-free nuclear power. But radiation can also save lives.

   
Newswise: UT Southwestern molecular geneticist wins Hill Prize from TAMEST
Released: 5-Feb-2024 9:30 AM EST
UT Southwestern molecular geneticist wins Hill Prize from TAMEST
UT Southwestern Medical Center

Russell DeBose-Boyd, Ph.D., Professor of Molecular Genetics at UT Southwestern Medical Center, has been awarded the Hill Prize in Biological Sciences from the Texas Academy of Medicine, Engineering, Science and Technology (TAMEST) in recognition of his long-standing research into a key mechanism necessary for cholesterol control.

Released: 2-Feb-2024 1:40 PM EST
Simple Blood Protein Tests Predict Which Lymphoma Patients Are Most Likely to Have Poor CAR T Outcomes
Roswell Park Comprehensive Cancer Center

As new cancer treatments become available, some of the most important ongoing research must look at ways to optimize those new approaches so that more patients can benefit from groundbreaking therapies.

Newswise: How Two Sisters Continue to Soar with Sickle Cell Disease
Released: 2-Feb-2024 9:30 AM EST
How Two Sisters Continue to Soar with Sickle Cell Disease
University of North Carolina Health Care System

Sydney and Sheridan Taylor of Durham, North Carolina, have lived with this rare genetic disorder all of their lives.



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