The National Institute of General Medical Sciences has awarded Justin Taylor, M.D., a researcher at Sylvester Comprehensive Cancer Center, a five-year grant totaling $1.92 million for his work to better define the role of XPO1 (Exportin-1) in cancer.
A new study from researchers with Sylvester Comprehensive Cancer Center and other top-tier cancer centers highlights the vital role that the immune system plays in determining the duration of patients’ remission from multiple myeloma.
An analysis of 10 years of health data showed that risk factors for needing mechanical ventilation changed for patients with newly diagnosed sepsis as more time passed after onset.
A broad new strategy could hold hope for treating virtually all blood cancers with CAR T cell therapy, which is currently approved for five subtypes of blood cancer.
Despite advancements in care, a Michigan Medicine study finds that the death rate for pulmonary embolism remains high and unchanged in recent years – more often killing men, Black patients and those from rural areas.
UChicago Medicine Comer Children’s Hospital was one of three sites to enroll patients in a clinical trial to test a potentially curative stem cell gene therapy for sickle cell disease. The results were promising.
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. Recent developments include a novel computational tool to detect single base pair DNA changes in single-cell sequencing data, a potential target to treat hypertension caused by drugs commonly used in organ transplants, further insights into the steps involved in genetic recombination, a novel treatment target for a subset of adenoid cystic carcinoma (ACC), a combination therapy that improves outcomes in certain patients with acute myeloid leukemia (AML), and a target for treating prolonged cytopenia in patients with relapsed/refractory large B cell lymphoma treated with chimeric antigen receptor (CAR) T cell therapy.
Playing a Mozart lullaby may help reduce the pain experienced by newborn babies undergoing a heel prick blood test, according to a randomised, blinded clinical trial involving 100 infants published in Pediatric Research.
Professor Ashok Venkitaraman, Director of the Cancer Science Institute of Singapore at the National University of Singapore, together with Assistant Professor Tobias Janowitz, Principal Investigator at the Cold Spring Harbor Laboratory in New York, and an international group of researchers from the USA and UK, have discovered that ketogenic diets delay tumour growth but accelerate cachexia, a wasting syndrome, an unintended side effect that could cause death.
En julio, salió al mercado el primer análisis de sangre directo al consumidor diseñado para evaluar el riesgo de un usuario de desarrollar la enfermedad de Alzheimer.
The National Comprehensive Cancer Network (NCCN) today announces the publication of NCCN Guidelines for Patients: Hodgkin Lymphoma in Children.
A study of 14 astronauts suggests that while space travel depletes red blood cells and bone, the body can eventually replenish them back on Earth with the help of fat stored in the bone marrow.
Researchers at Albert Einstein College of Medicine have found that the virus responsible for chikungunya fever can spread directly from cell to cell—perhaps solving the longstanding mystery of how the virus, now emerging as a major health threat, can manage to escape antibodies circulating in the bloodstream.
New research shows blood cancers are often misdiagnosed, an NCI grant to develop a urine test for prostate cancer, a surgeon-scientist receives Sylvester’s first DoD grant to study pancreatic cancer, bolstering emergency preparedness for climate-driven disasters, and more are included in this month’s tip sheet .
Patients with the genetic disorder hemophilia A receive factor VIII protein replacement treatments to replenish this clotting protein in their blood, thus preventing dangerous bleeding. Unfortunately, about 30 percent of these patients develop antibodies against the treatment and until now, despite more than 80 years of clinical experience with this complication, little has been known about its mechanism.
A brief roundup of news and story ideas from the experts at UCLA Health.
The new observation, made by UNC School of Medicine’s Stephan Moll, MD, and Jacquelyn Baskin-Miller, MD, suggests that a life-threatening blood clotting disorder can be caused by an infection with adenovirus, one of the most common respiratory viruses in pediatric and adult patients.
A study shows new steps toward more patients getting gene therapy
Innovative technology that creates ultra-thin layers of human cells in tube-like structures could spur development of lifelike blood vessels and intestines in the lab.
Blood disorders known as myelodysplastic syndromes/neoplasms are commonly misdiagnosed – putting patients at increased risk for treatment mistakes and other potentially harmful consequences. A new study highlights the vital need for strong coordination between clinicians and skilled pathologists to ensure accurate, timely diagnosis of blood cancers.
Huntsman Cancer Institute investigators find a way to reduce infection after pancreatic surgery, discover the best treatment combination that’s cost effective for prostate cancer patients, and learn lung cancer patients receiving chemotherapy have more emergency department visits. They also found a genetic mutation that makes anemia more likely after chemotherapy, and a non-invasive way to remove brain tumors.
University of Melbourne researchers have developed a fast, inexpensive and scalable method for engineering blood vessels from natural tissue.
A roundup of the latest medical discoveries and faculty news at Cedars-Sinai.
Niki Patel, MD, a fellowship-trained hematologist-oncologist board certified in internal medicine and medical oncology, has joined the Division of Medical Oncology at Cedars-Sinai Cancer. She is treating patients in Pasadena at Huntington Cancer Center at Huntington Health, an affiliate of Cedars-Sinai.
Lab-on-a-chip technologies can ensure a more successful transfusion workflow by enabling objective assessment of stored RBC units using quality metrics identified by -omics and machine learning.
In a step forward in the development of genetic medicines, researchers at Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body. If translated into the clinic, this approach could expand access and reduce the cost of gene therapies for blood disorders, many of which currently require patients receive chemotherapy and a stem cell transplant. The findings were published today in the journal Science.
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Chimeric antigen receptor (CAR)-T cells are a powerful, new form of cancer therapy that are being studied to treat blood cancers. Using a new approach, Yale Cancer Center researchers at Yale School of Medicine found a new way to substantially improve the effectiveness of CAR-T cell therapy. The new study was published in Nature Immunology on July 27.
Blood banks always say it’s safe to give blood. But is it safe to receive? A Penn State Health expert discusses all the ways professionals keep your blood pathogen-free.
Scientists at UT Southwestern Medical Center and Children’s Medical Center Dallas have discovered in mice how high cholesterol causes blood vessels to become inflamed, a necessary prerequisite for atherosclerosis – the “hardening of the arteries” responsible for most heart attacks and strokes. The findings, published in Nature Communications, could lead to new interventions to protect against cardiovascular diseases (CVD), the leading cause of death globally.
Chula Medicine researchers have successfully published an article on the injection of patient’s own platelets rich plasma into the shoulder ligaments resulting in pain reduction, heal torn ligaments and restore torn muscles as an alternative to surgery while reducing the side effects of prolonged use of pain medications.
New Day Diagnostics LLC is pleased to announce that it has entered into an asset purchase agreement with Epigenomics AG (Frankfurt Prime Standard: ECX, OTCQX: EPGNY), a molecular diagnostics company focused on blood testing for the early detection of cancer.
Cedars-Sinai Guerin Children’s investigators have advanced our understanding of the role that blood platelets play in Kawasaki disease, a serious illness that primarily affects children younger than 5 years old and causes their blood vessels to swell.
In a new study, University of Utah Health researchers have shown that a particular version of a gene may contribute to the higher severity of stroke seen among Black Americans. The findings could help scientists develop more effective stroke medications for people who carry the gene.
At the 2023 AACC Annual Scientific Meeting & Clinical Lab Expo, laboratory experts will present cutting-edge research and technology that is shaping the future of clinical testing and patient care.
During the AACC - Annual Scientific Meeting & Clinical Lab Expo, held in Anaheim, California (USA) from July 23rd to 27th, the Brazilian health tech company Hilab, specializing in clinical analysis tests, participated in the congress alongside ABIMO - Brazilian Association of Medical Devices Industry.
University of Maryland School of Medicine (UMSOM) researchers engineered a new type of CAR T-cell therapy that, in preclinical studies, selectively attacked cancer cells while sparing healthy cells, potentially reducing the likelihood of toxic side effects from this innovative cancer treatment.
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
A team of researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS), led by Assistant Professor Anand Jeyasekharan, has discovered a unique combination of oncogenes that could predict treatment resistance, and hence unfavourable outcomes, of patients with Diffuse large B cell lymphoma (DLBCL), the most common type of blood cancer in Singapore and globally.
Routine blood pressure readings recorded in the first half of pregnancy can be divided into 6 distinct patterns that can effectively stratify patients by their risk of developing preeclampsia and gestational hypertension later in pregnancy, Kaiser Permanente researchers found.
Researchers continue to refine and improve targeted drug therapies that have changed the most common form of adult leukemia – from an incurable to a chronic condition. New data published in the New England Journal of Medicine offers another treatment option for patients who have stopped responding to the first and second generation drugs.
Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease and beta thalassemia. Scientists at St. Jude Children’s Research Hospital and the Broad Institute of MIT and Harvard found base editing increased fetal hemoglobin production in a new treatment.
The results of a clinical trial have shown that a drug commonly used for patients with bleeding disorders has the potential to be used to lessen the side effects of blood-thinning drugs for patients who have experienced a stroke.
A national study of blood ferritin and hemoglobin levels from tween, teen and young adult females suggests routine screening might be needed for iron deficiency and anemia.
A blood-based four-protein panel (4MP), when combined with a lung cancer risk model (PLCOm2012), can better identify those at high risk of dying from lung cancer than the current U.S. Preventive Services Task Force (USPSTF) criteria.
A multi-faceted device for effectively treating deep, non-compressible, and irregularly-shaped wounds has been engineered by the scientists at the Terasaki Institute for Biomedical Innovation (TIBI).
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