In a new meta-analysis of randomized, placebo-controlled COVID-19 vaccine trials, researchers compared the rates of adverse events reported by participants who received the vaccines to the rates of adverse events reported by those who received a placebo injection.
Rates of cervical cancer screening have dropped in the U.S., with screening rates lowest among Asian and Hispanic women, as well as women who live in rural areas, don’t have insurance, or identify as LGBQ+, according to researchers with The University of Texas Health Science Center at Houston (UTHealth Houston).
Even though clinical trials haven’t shown it works against COVID-19, doctors continue to prescribe ivermectin – and a new study suggests health insurers are heavily subsidizing the cost of those prescriptions.
January 15 will mark the first time in seven months that the families of more than 61 million children in the United States will not receive a monthly payment of the advance Child Tax Credit (CTC), after Congress failed to pass the Build Back Better Act, which would extend this benefit enacted last spring as part of the Biden administration’s COVID-19 relief package.
A new international study offers a clearer picture of the impact of COVID-19 infection and the risk of severe outcomes on young people around the world.
The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recently published studies in basic, translational and clinical cancer research from MD Anderson experts. Current advances include an anti-CD19 chimeric antigen receptor (CAR) T cell therapy to treat follicular lymphoma, targeted therapies for urothelial cancers and advanced breast cancers, understanding the tumor microenvironment and immune landscape in pancreatic cancer, a link between depression risk and androgen deprivation for prostate cancer, and the discovery of new therapeutic targets for Alzheimer’s disease, liver cancer and aggressive breast cancer.
How to better detect chronic obstructive pulmonary disease (COPD) in low- and middle-income countries is a question that has long plagued the global medical community.
Nearly half of people in a large U.S. study reported misusing prescription drugs between ages 18-50, which made them more likely to develop substance use disorder symptoms as adults––especially those whose misuse peaked later in life.
Adults with obesity who had weight-loss surgery and achieved substantial weight loss prior to contracting COVID-19 reduced their risk for developing severe outcomes from the infection by 60% compared to those who did not have surgery, according to a new Cleveland Clinic study published online today in the journal JAMA Surgery.
CLEVELAND: A Cleveland Clinic study shows that among patients with obesity, prior weight loss achieved with bariatric surgery was associated with a 60% lower risk of developing severe complications from COVID-19 infection. The research was published in the journal JAMA Surgery.
This year the medical and research advancements from the Icahn School of Medicine at Mount Sinai and the Mount Sinai Health System ranged from COVID-19, to PTSD, to the first ever successful trachea transplant surgery. Our doctors and researchers were not only at the forefront of the pandemic providing expertise and new studies surrounding the virus, its symptoms and effects, but also excelling in revolutionary surgeries and progressive research to continue showcasing Mount Sinai as a top medical institution and medical school in the country. Here are some of Mount Sinai’s breakthrough stories of the year:
Since the introduction of electronic cigarettes, or e-cigarettes, to the United States in 2006, intense debate has surrounded the marketing, regulation and use of these nicotine-delivery products.
Children in a study cohort of young patients requiring ICU care for critical illness had an average of two weeks of school absences; half of primary caregivers missed work during the same period.
Study identifies racial and ethnic disparities in hospital mortality for COVID and non-COVID patients alike, highlights urgent need to address systemic inequities in health care and improve care for those who are impacted the hardest by the virus, directly and indirectly.
Patients hospitalized with COVID-19 who had a combination of high blood pressure, obesity, diabetes, or other conditions associated with metabolic syndrome were at much higher risk of acute respiratory distress syndrome and death, according to an international study published in JAMA Network Open.
For the first time since national data have been tracked in the United States, stigma toward people with depression has dropped significantly, according to a study by Indiana University researchers. However, stigma levels for other mental illnesses remained stagnant and, in some cases, have increased.
Being the parent or sibling of a child with a life-threatening condition can take a mental and physical toll on other members of the family. A new study is one of the first to empirically measure the extent of this burden on families, with parents and siblings 50% to 70% more likely than their peers to receive health care for mental and physical health issues, accompanied by medication for these issues, than families of children without a life-threatening condition.
GLP-1 RA treats diabetes and is linked to positive outcomes for heart disease patients, yet inequities were found in its use along racial, ethnic, and economic lines
A recent, substantial decline in lung cancer deaths is associated with earlier diagnosis of lung cancer than in the past, supporting the need for increased use of screening to save lives, according to a Mount Sinai study published in JAMA Network Open in December.
Oropharyngeal cancer incidence among men is continuing to rise rapidly in nearly all 50 states and among women living in states in the Midwest and Southeast regions, according to a new study by investigators at The University of Texas Health Science Center at Houston (UTHealth Houston) School of Public Health in JAMA Otolaryngology-Head & Neck Surgery.
With numerous recent studies demonstrating that antibiotics work as well as surgery for most uncomplicated appendicitis cases, the non-surgical approach can now be considered a routine option, according to a review article in JAMA.
Providing individual hotel rooms with supports to people experiencing homelessness who were at high risk of severe COVID-19 led to a 2.5-fold decrease in SARS-CoV-2 rates compared to rates seen in Chicago city shelters, as well as improvements in other health measures and housing outcomes.
COVID-19 convalescent plasma showed a likely benefit for patients early in the pandemic before remdesivir and corticosteroids were in use, according to results of a landmark study published today in JAMA that included physician-scientists at (UTHealth Houston.
Researchers at UCLA Jonsson Comprehensive Cancer Center led a large international study providing what is believed to be the first evidence (albeit indirect) that a recently approved imaging technique improves risk-stratification and long-term prognostic capabilities for patients with high-risk prostate cancer whose conventional imaging showed only localized disease.
Nearly a fourth of pregnant and recently pregnant women in a new study say they’ve been unable to afford necessary health care, and three fifths report concern about paying medical bills.
For patients with the blood cancer multiple myeloma, vaccination against COVID-19 provides some protection against coronavirus infection but to a far lower degree than the general population of cancer survivors, a new study by Dana-Farber Cancer Institute investigators shows.
A subtle smile emerged on Dr. James Leidner’s face as he envisioned telling people of the unusual contribution he made to mankind’s mission to Mars.
Maternal morbidity risks may continue well into the late postpartum period, especially for individuals who are Black or have depression or anxiety, new research suggests.
In this study of 3,000 adults with cataracts, the risk of developing dementia was lower in participants who underwent cataract removal compared with those who didn’t.
New Research shows that women treated for melanoma have twice the mortality rate of men when given two immunotherapies at one time.
Two studies based in Seattle provide evidence that public policies to reduce consumption of added sugars through taxes on sugar-sweetened beverages are effective and sustainable.
The rate of cervical cancer among women living in neighborhoods with the lowest socioeconomic indices is nearly two times higher than the rate among those who live in areas with the highest indices.
A new study led by researchers at UCLA Health has found that cognitive behavioral therapy (CBT-I) prevented major depression, decreasing the likelihood of depression by over 50% as compared to sleep education therapy in adults over the age of 60 with insomnia.
The widespread use of masks during the COVID-19 pandemic has posed numerous communication barriers, muffling speech and impeding lip-reading.
A new study summarized in a research letter to be published in JAMA Pediatrics reveals that a number of factors, including negative impacts from the pandemic during pregnancy and reports of discrimination, made it less likely that infants received their recommended vaccinations in the first months of their lives.
It’s well known that smoking causes lung cancer. But a new study suggests you can lower―or even erase―the risk of dying from lung cancer associated with continuous smoking if you quit when you’re young.
Patients who made appointments to see their primary care doctors by video or over the phone did not seek substantially more follow-up care overall than those who had traditional in-person visits, according to Kaiser Permanente research published November 16 in JAMA Network Open.
In recent studies, researchers find 1) Few people get a timely diagnosis of dementia, especially if they are of color with no college degree. 2) No dementia risk in members of military over 65. 3) Link to hearing and dementia.
A large analysis of health records from 87 health care centers across the United States found that people taking a class of antidepressants called selective serotonin reuptake inhibitors (SSRIs), particularly fluoxetine, were significantly less likely to die of COVID-19 than a matched control group.
Geochemist Lex van Geen works at the intersection of public health and environmental risks.
Patients with a rare immunodeficiency disorder who are treated with lifelong immunoglobulin replacement therapy (IRT) have a lower risk of premature death than patients treated with a hematopoietic stem cell transplant (HSCT), but they also have a reduced quality of life and must assume a substantial financial burden, according to a new study led by Children’s Hospital of Philadelphia (CHOP). Using a computational model to calculate the costs and benefits of IRT and HSCT for patients with agammaglobulinemia, the researchers concluded that the high cost of IRT in the U.S. undermines its cost-utility, particularly when compared to Canada and European countries, where the cost of IRT is nearly a third of what it is in the U.S.
Female physicians who are parents made more changes and experienced greater depression and anxiety during the pandemic than male physician-parents. Data from before the pandemic shows a gender gap in new-onset depression.
Consuming a low amount of caffeine during pregnancy could help to reduce gestational diabetes risk, according to researchers in the Perelman School of Medicine at the University of Pennsylvania.
A Cleveland Clinic study shows that patients with obesity and advanced fatty liver disease who had bariatric weight loss surgery significantly lowered their future risk of liver disease complications and serious cardiovascular disease compared with patients who did not have surgery.
A new Cleveland Clinic study shows that patients with obesity and advanced fatty liver disease who had bariatric surgery (weight-loss surgery) significantly lowered their risk for severe liver disease and serious cardiovascular disease, including heart attack and stroke, compared to patients who did not have the surgery.
In a large study led by Yale Cancer Center, more men received a prostate-specific antigen or PSA test to detect prostate cancer following revisions to the recommendation by the U.S. Preventative Services Task Force on screening. The results also showed significant increases in PSA testing among older men, a group for whom screening is not routinely recommended.
A new Cleveland Clinic study found that people with certain sleep disorders have more severe outcomes from COVID-19, including a 31 percent higher rate of hospitalization and mortality.
Cancer patients who are ineligible for clinical trials receive immune checkpoint inhibitors (ICI) at greater rates than patients who are trial eligible despite no survival benefit, according to a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania. The study, published in JAMA Oncology, suggests that the positive results for phase 3 clinical trial participants receiving ICI treatment may not translate to patients who are ineligible for trials due to factors such as organ dysfunction.
A new Harvey L. Neiman Health Policy Institute study of nearly 800,000 men found that between 2011 and 2017 black patients were 24% less likely than white patients to have a prostate MRI after receiving an elevated (prostate-specific antigen) PSA score. For patients with an elevated PSA, use of prostate MRI prior to prostate biopsy has increased substantially in recent years as MRI can improve identification of clinically significant prostate cancer and obviate the need for biopsy, thus decreasing overdiagnosis of these cases. This JAMA Network Open study was based on 794,809 men, age 40 or older, with a PSA test using claims data from the Optum Clinformatics Data Mart Database. Of these men, 51,500 had an PSA score >4ng/mL. The study found that patients with Medicare compared to commercial insurance were less likely to have a prostate MRI as were patients with HMO insurance plans compared to other plan types.
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