Feature Channels: Biotech

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University of Maryland School of Medicine (UMSOM) Dean Mark T. Gladwin, MD, announced today that Bradley A. Maron, MD, Associate Professor of Medicine at Brigham & Women’s Hospital (BWH) and Harvard Medical School (HMS), and Co-Director of the Pulmonary Vascular Disease Center at the VA Boston Healthcare System, has been appointed Co-Director of the UMB’s new Institute for Health Computing (UM-IHC), Director of Scientific Operations for the UM-IHC at UMSOM, as well as Senior Associate Dean for Precision Medicine at the UMSOM, effective May 1, 2023.

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An upgraded computational tool from St. Jude Children’s Research Hospital can find potentially druggable hidden drivers of cancer and other biological processes using multi-omics data.

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Applying machine learning models, a type of AI, to data collected passively from wearable devices can identify a patient’s degree of resilience and well-being, according to investigators at the Icahn School of Medicine at Mount Sinai in New York. The findings, reported in the May 2nd issue of JAMIA Open, support wearable devices, such as the Apple Watch®, as a way to monitor and assess psychological states remotely without requiring the completion of mental health questionnaires.

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Gene-editing therapy aimed at two targets – HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells – can effectively eliminate HIV infection. The study is the first to combine a dual gene-editing strategy with antiretroviral drugs to cure animals of HIV-1.

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What if your physician could predict if—or when—you might experience a heart attack, cardiac arrest or another heart-related problem?

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This agreement will enable FAU and Insightec to collaborate to advance scientific knowledge about the use of focused ultrasound to treat brain diseases, including Parkinson’s disease and Alzheimer’s disease. By harnessing acoustic energy, Insightec’s innovative technology uses focused ultrasound to treat diseases in different ways.

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Seven University of Utah Health projects have received seed grants that could promote the development and use of more scientifically based digital health applications in daily health care.

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Researchers have developed a biosynthetic “clock” that keeps cells from reaching normal levels of deterioration related to aging. They engineered a gene oscillator that switches between the two normal paths of aging, slowing cell degeneration and setting a record for life extension.

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Mayo Clinic ha logrado avances importantes en la biofabricación de productos terapéuticos en etapa inicial. La atención se centra en medicamentos nuevos derivados del cuerpo humano, llamados productos bioterapéuticos, que están dando forma al futuro de la medicina.

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A Mayo Clinic fez avanços significativos na biomanufatura de produtos terapêuticos de estágio inicial. O foco está em novos medicamentos derivados do organismo humano, chamados de produtos bioterapêuticos, que estão definindo o futuro da medicina.

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Creating accessible, affordable equipment to democratize research is the foundation of frugal science. Now, with a new five-year grant from the National Institutes of Health (NIH), Bhamla and Standeven will pave the way to bring frugal science to high schools across Georgia.

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As part of its “Moon to Mars” initiative, NASA plans to send humans farther into space than ever before.

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Scientists demonstrated that human 14-3-3 proteins, that are known for their role in replication of many viruses, bind differentially with more often mutating regulatory part of nucleoprotein (N protein) of coronavirus SARS-CoV-2.

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Researcher will discuss the study which involved a sleeping aid known as suvorexant that is already approved by the Food and Drug Administration (FDA) for insomnia, hints at the potential of sleep medications to slow or stop the progression of Alzheimer’s disease.

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Scientists have long been intrigued by the remarkable properties of spider silk, which is stronger than steel yet incredibly lightweight and flexible. Now engineers have made a significant breakthrough in the fabrication of synthetic spider silk, paving the way for a new era of sustainable clothing production.

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An essential pillar of Earth’s ecological system, fungi have long been used to better the lives of humans. While these organisms are still vastly understudied, a new review paper suggests that their unique genomes could be used to make progress in the biotech industry.

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The proposed material is chemically similar to mammalian proteins and is non-toxic, therefore contributing to fast adherence and division of human stem cell cultures. This development will help accelerate cell culture growth, which are used in medicine as a replacement for damaged tissue.

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Scientists in Melbourne have designed a new type of oral capsule that could mean pain-free delivery of insulin and other protein drugs.

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University of Pittsburgh researchers developed a novel approach that promoted bone regeneration in mice without implantation of bone tissue or biomaterials.

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Hackensack Meridian Health, the state’s largest and most comprehensive health network, is partnering with Etta.io., a Denver-based healthcare technology startup that builds Artificial Intelligence (AI) applications to detect tumors difficult to see with the naked eye, even for specialists.

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Today, foldable phones are ubiquitous. Now, using models that predict how well a flexible electronic device will conform to spherical surfaces, University of Wisconsin–Madison and University of Texas at Austin engineers could usher in a new era in which these bendy devices can integrate seamlessly with parts of the human body.

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Roots of a traditional medicine plant called the orange climber can fluoresce an ethereal blue hue under ultraviolet (UV) light. And now, researchers in ACS Central Science have identified two coumarin molecules that could be responsible, one of the which could someday be used for medical imaging.

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Cedars-Sinai Cancer’s commitment to convergent science—the deep melding of computational, physical engineering and biological sciences—is evident throughout its 2023 Annual Report.

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Cedars-Sinai investigators, in collaboration with Axiom Space of Houston, are sending stem cells to space in early May to explore whether microgravity can make it easier and more efficient to produce large batches of stem cells.

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Researchers have made huge strides in ensuring that red blood cell substitutes – or artificial blood – are able to work safely and effectively when transfused into the bloodstream.

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Scientists at St. Jude Children’s Research Hospital and the Broad Institute of MIT and Harvard showed how prime editing can correct mutations that cause sickle cell disease in a potentially curative approach.

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Dr. Song Soo-chang's research team at the Center for Biomaterials, Korea Institute of Science and Technology (KIST, President Yoon Seok-jin), revealed the first development of poly(organophosphazene) hydrogel-based temperature-sensitive bioink that stably maintained its physical structure only by temperature control without photocuring, induced tissue regeneration, and then biodegraded in the body after a certain period of time.

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New AI tool accurately predicts both overall survival and disease-free survival after colorectal cancer diagnosis. The model uses visual markers on pathology images to glean insights into a tumor’s genomic profile and predicts tumor behavior, disease progression, treatment response. The new model could help augment clinical decision-making. Because the AI tool relies on images alone, it could be particularly valuable for hospitals lacking the technology or expertise to perform sophisticated genomic profiling of tumor tissues.