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Penn Study Identifies Potent Inhibitor of Zika Entry Into Human Cells

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Researchers identified a panel of small molecules that inhibit Zika virus infection, including one that stands out as a potent inhibitor of Zika viral entry into relevant human cell types. They screened a library of 2,000 bioactive compounds for their ability to block Zika virus infection in three distinct cell types using two strains of the virus.

Medicine

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Urban Health, Population Health, Cities, Policy

First-Ever Online Data Tool Allows City Leaders to Examine Health of Their Urban Populations & Take Action

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Responding to demands from cities across the country, NYU School of Medicine’s Department of Population Health, NYU’s Robert F. Wagner School of Public Service, and the National Resource Network, with support from the Robert Wood Johnson Foundation, are launching the City Health Dashboard. The online data visualization tool will greatly improve city-level understanding of health and empower mayors, city managers, health officials, and other local stakeholders to enact policies that target the risk factors and health conditions that most impact their communities.

Medicine

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HIV Therapy Could Be Contributing to Syphilis Outbreak

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Drugs used to treat HIV could affect how the body responds to syphilis, inadvertently contributing to a current outbreak, a new study suggests.

Medicine

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Hospital Costs, Physician Charges, Health Care Costs, Health Insurance

Patients Face ‘Surprise’ Medical Bills From Out-of-Network Specialists

The average anesthesiologist, emergency physician, pathologist and radiologist charge more than four times what Medicare pays for similar services, often leaving privately-insured consumers stuck with surprise medical bills that are much higher than they anticipated, new research in JAMA suggests.

Medicine

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Nerve, Nerve Damaging Protein, Protein Particles, Prions, Bacteria, Misfolded Protein, Clostridium botulinum, C. Botulinum, Forming Prions, Bacterial Survival, Amyloid

New Trick Up Their Sleeve

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Nerve-damaging protein particles called prions have long been known to exist in mammals. Now, in a surprising discovery, investigators from Harvard Medical School report they have found evidence that bacteria can also make prions. Prions—self-propagating clumps of misfolded protein—have been identified as the cause of several rare but universally fatal neurodegenerative conditions, including bovine spongiform encephalopathy, popularly known as mad cow disease.

Medicine

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Herpes Simplex Virus 2, vaccine candidates, PLoS Pathogens

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 19-Jan-2017 2:00 PM EST

Medicine

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GeoVax, Hepatitis B, Vaccine, Dr. Ming Luo

GeoVax to Collaborate with Georgia State on Development of Hepatitis B Therapeutic Vaccine

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The Georgia State University Research Foundation has entered into a research collaboration agreement with GeoVax Labs, Inc., a Georgia-based biotechnology company developing human vaccines, to advance development of a therapeutic vaccine for treatment of chronic Hepatitis B infections.

Medicine

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Genome Sequencing, Newborn Screening Programs

Are You Ready to Explore Baby’s Genome?

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A national consortium of clinical geneticists is studying the ins and outs of potentially using genome sequencing for newborn health screenings and beyond.

Medicine

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Dermatology, Sarcoidosis, Tech, APP, Apple, Rare Diseases, Research

Penn Medicine Launches First Apple ResearchKit App for Sarcoidosis Patients

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Penn Medicine today launched its first Apple ResearchKit app, focused on patients with sarcoidosis, an inflammatory condition that can affect the lungs, skin, eyes, heart, brain, and other organs. The effort marks Penn’s first time using modules from Apple’s ResearchKit framework, as part of the institution’s focus on mobile health and innovative research strategies.

Medicine

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Endocrine Society, Journal of Clinical Endocrinology and Metabolism , Endocrinology, Type 1 Diabetes, Microbiome, Microbiota, Intestinal Bacteria, Inflammation

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 19-Jan-2017 2:00 PM EST

Medicine

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Affordable Care Act (ACA), Health Insurance, medicaid expansion, Mental Health, Substance Abuse

More with Mental Illness and Substance Use Disorders Have Health Insurance

Significantly more people with mental illness and substance use disorders had insurance coverage in 2014 due to the expansion of health insurance under the Affordable Care Act (ACA), but many barriers to treatment remain, new Johns Hopkins Bloomberg School of Public Health research suggests.

Medicine

Science

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alcoholic liver disease, Binge Drinking, heavy drinking, rodent study, liver dysfunction, Liver Damage, Fatty Liver

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 19-Jan-2017 5:00 PM EST

Medicine

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Leishmania, persistent infection, Latent Infection, Immune System

Persistent Infection Keeps Immune Memory Sharp, Leading to Long-Term Protection

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Microbes can persist in people for years after an illness, even in people who are healthy and immune to recurrence. Now, researchers have found a clue to this seeming paradox: Persistent microbes are constantly multiplying and being killed, keeping the immune system prepared for any new encounters.

Medicine

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Physical Therapy, Rehabiliation

Harris Health Occupational Therapist Receives Horizon Award

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Catherine Graves, a registered occupational therapist at Harris Health System, received the Horizon Award from the Texas Occupational Therapy Association. The award is given to a practitioner with less than five years of experience and who has made great contributions to the profession.

Medicine

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Health, health reform, Insurance, Afforable Care Act

Access to Health Care Strengthens Communities

New research on an aspect of the ACA/health care debate that hasn’t really been discussed—the social impact on communities. Vanderbilt professor Tara McKay was able to control for income level and other factors and still finds issues with trust, support and other issues in communities where members are uninsured.

Medicine

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Vaccine, Pneumonia Vaccinations, flu, Whooping Cough, Shingles, shingles prevention, Flu Prevention, Pneumonia, Prevnar, Tdap

FOUR Important Vaccines Adults Shouldn’t Skip

Vaccines are an important part of routine healthcare for adults, seniors and women who are pregnant. Older adults and seniors need protection against infectious illnesses just like children do. Dr. Cathleen Veach lists the four most important vaccines for adults.

Medicine

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sick kids, staying home from school, sick day, flu

Parents Struggle with When to Keep Kids Home Sick From School

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Opinions among parents differ when it comes to how sick is too sick to stay home, or the importance of sick day consequences such as parents missing work or kids missing tests.

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"Mysterious" Non-Protein-Coding RNAs Play Important Roles in Gene Expression, NCI-Designated Cancer Centers Endorse Updated HPV Vaccination Recommendations, and More in the Cancer News Source

Click here to go directly to the Cancer News Source

Medicine

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UTHealth Neonatal Researcher Funded by NIH to Study Plastic Products Used in NICUs

The impact of the chemicals in the plastic products used in pediatric intensive care units will be the focus of a new $1 million study led by Andrea Duncan, M.D., M.S.ClinRes, associate professor at McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth) and an attending physician with Children’s Memorial Hermann Hospital.

Medicine

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Urology, Psa Test, Prostate Cancer

Ben Stiller's Surgeon Edward Schaeffer, MD Is Available to Discuss New Prostate Cancer PSA Testing Study

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