Patients undergoing cerebral angiography and neurointerventional procedures on the brain are at very low risk of infection—even without preventive antibiotics, reports a study in the March issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
Researchers at Albert Einstein College of Medicine have discovered how the most common genetic mutations in familial Parkinson’s disease damage brain cells.
A study led by St. Jude Children’s Research Hospital has discovered mutations in two genes that lead to the death of nerve cells in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, and related degenerative diseases.
Combining hospital MRIs with the mathematical tool known as network analysis, a group of researchers at UC San Francisco and UC Berkeley have mapped the three-dimensional global connections within the brains of seven adults who have genetic malformations that leave them without the corpus callosum, which connects the left and right sides of the brain.
For the first time, scientists have shown that transplanted eyes located far outside the head in a vertebrate animal model can confer vision without a direct neural connection to the brain. Tufts University biologists used a frog model to shed new light – literally – on one of the major questions in regenerative medicine and sensory augmentation research.
Researchers have identified a possible treatment window of several years for plaques in the brain that are thought to cause memory loss in diseases such as Alzheimer’s. The Mayo Clinic study is published in the Feb. 27 online issue of Neurology, the medical journal of the American Academy of Neurology.
Neuroscientists should help to develop compelling digital games that boost brain function and improve well-being, say two professors specializing in the field in a commentary article published in the science journal Nature.
For chronic pain sufferers, such as people who develop back pain after a car accident, avoiding the harmful effects of stress may be key to managing their condition. This is particularly important for people with a smaller-than-average hippocampus, as these individuals seem to be particularly vulnerable to stress.
A novel way to image the brain’s glymphatic pathway may provide the basis for a new strategy to evaluate Alzheimer's disease susceptibility, according to a research paper published in The Journal of Clinical Investigation.
The American Academy of Neurology (AAN) is releasing a list of five tests, procedures, and treatments that doctors and their patients should question as part of today’s announcement regarding the “Choosing Wisely” campaign by the American Board of Internal Medicine (ABIM) Foundation. The list is published in the February 21, 2013, online issue of Neurology, the medical journal of the American Academy of Neurology. Sixteen other medical societies are also releasing their lists.
In the weeks, months and years after a severe head injury, patients often experience epileptic seizures that are difficult to control. A new study in rats suggests that gently cooling the brain after injury may prevent these seizures.
Triglyceride lipid emulsions rich in an omega-3 fatty acid injected within a few hours of an ischemic stroke can decrease the amount of damaged brain tissue by 50 percent or more in mice, reports a new study by researchers at Columbia University Medical Center. The results suggest that the emulsions may be able to reduce some of the long-term neurological and behavioral problems seen in human survivors of neonatal stroke and possibly of adult stroke, as well.
Contrary to other research, a new study found that the total level of antioxidants in people’s diets is not related to their risk of developing stroke or dementia. The study is published in the February 20, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology. Antioxidants such as lycopene, beta-carotene and vitamins C and E are found in many foods.
A team of researchers at UC San Francisco has uncovered the neurological basis of speech motor control, the complex coordinated activity of tiny brain regions that controls our lips, jaw, tongue and larynx as we speak.
New findings by Columbia researchers suggest that along with amyloid deposits, white matter hyperintensities (WMHs) may be a second necessary factor for the development of Alzheimer’s disease.
In a pair of new papers, researchers at the University of California, San Diego School of Medicine and the Royal Netherlands Academy of Arts and Sciences upend a long-held view about the basic functioning of a key receptor molecule involved in signaling between neurons, and describe how a compound linked to Alzheimer’s disease impacts that receptor and weakens synaptic connections between brain cells.
A new study led by an international team of biologists has identified some of the brain chemicals that allow seals to sleep with half of their brain at a time.
A new Columbia Engineering study finds that the infant brain does not control its blood flow the same way as the adult brain, that the control of brain blood flow develops with age. These findings could change the way researchers study brain development in infants and children.
One of the most challenging issues in stroke care involves the use of clot-busting drugs such as tPA. In Expert Review of Neurotherapeutics, stroke specialists offer guidance on commonly asked questions about the use of these drugs.
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New Mayo Clinic research suggests that blood may hold clues to whether post-menopausal women may be at an increased risk for areas of brain damage that can lead to memory problems and possibly increased risk of stroke. The study shows that blood’s tendency to clot may contribute to areas of brain damage called white matter hyperintensities. The findings are published in the Feb. 13 online issue of Neurology, the medical journal of the American Academy of Neurology.
For many patients with difficult-to-treat neuropathic pain, deep brain stimulation (DBS) can lead to long-term improvement in pain scores and other outcomes, according to a study in the February issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
Two patients freed from severe to disabling effects of dystonia through deep brain stimulation therapy continued to have symptom relief for months after their devices accidentally were fully or partly turned off, according to a report published online Feb. 11 in the journal Movement Disorders.
Researchers at Mayo Clinic have discovered an abnormal protein that accumulates in the brains of many patients affected with two common neurodegenerative disorders — amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig’s disease, and frontotemporal dementia.
Strokes that occur during or shortly after surgery can be devastating, resulting in longer hospital stays and increased risks of death or long-term disability, but prompt identification and treatment can improve neurologic outcomes.
Researchers at the University of California, San Diego School of Medicine say overexpression of a protein called alpha-synuclein appears to disrupt vital recycling processes in neurons, starting with the terminal extensions of neurons and working its way back to the cells’ center, with the potential consequence of progressive degeneration and eventual cell death.
In an update to previous research, Johns Hopkins neurologists say minimally invasive delivery of the drug tPA directly into potentially lethal blood clots in the brain helped more patients function independently a year after suffering an intracerebral hemorrhage (ICH), a deadly and debilitating form of stroke. Rates of functional recovery with the active tPA treatment far surpassed those achieved with standard “supportive” therapy that essentially gives clots a chance to shrink on their own.
Injury to the subcortical structures of the inner brain is a major contributor to worsening neurological abnormalities after "awake craniotomy" for brain tumors, reports a study in the February issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
For women with aneurysms involving the brain blood vessels, pregnancy and delivery don't appear to increase the risk of aneurysm rupture, reports a paper in the February issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
The number of people with Alzheimer’s disease is expected to triple in the next 40 years, according to a new study published in the February 6, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Wearing a nerve stimulator for 20 minutes a day may be a new option for migraine sufferers, according to new research published in the February 6, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology.
The number of people with Alzheimer’s disease is expected to triple in the next 40 years, according to a new study by researchers from Rush University Medical Center published in the February 6, 2013, online issue of Neurology, the medical journal of the American Academy of Neurology.
Researchers have identified a protein trafficking defect within brain cells that may underlie the common form of Parkinson's disease. The defect is at a point of convergence for the action of at least three different genes that had been implicated in prior studies of Parkinson's disease. Whereas most molecular studies focus on mutations associated with rare familial forms of the disease, these findings relate directly to the common non-familial form of Parkinson’s.
Wichita State University biochemistry professor Kandatege Wimalasena believes his studies will identify molecular causes and eventually lead to the development of effective preventive and therapeutic strategies for Parkinson's.
Data from the largest multicenter study accessing cognitive functioning in children with multiple sclerosis (MS) reveals that one-third of these patients have cognitive impairment, according to a research paper published in the Journal of Child Neurology. Led by Lauren B. Krupp, MD, Director of the Lourie Center for Pediatric Multiple Sclerosis at Stony Brook Long Island Children’s Hospital, the study indicates that patients experience a range of problems related to cognition.
A team of academic researchers has pinpointed how vitamin D3 and omega-3 fatty acids may enhance the immune system's ability to clear the brain of amyloid plaques, one of the hallmarks of Alzheimer's disease. In a small pilot study, the scientists identified key genes and signaling networks regulated by vitamin D3 and the omega-3 fatty acid DHA (docosahexaenoic acid) that may help control inflammation and improve plaque clearance.
Vanderbilt neuroscientist Kenneth Catania has performed a series of tests that shows definitively that the common mole uses stereo sniffing to locate its prey.
Johns Hopkins researchers have found that mice can recover from physically debilitating strokes that damage the primary motor cortex, the region of the brain that controls most movement in the body, if the rodents are quickly subjected to physical conditioning that rapidly “rewires” a different part of the brain to take over lost function.
Each year, as many as 500,000 Americans experience mini strokes called transient ischemic attacks (TIAs). Up to 15 percent will go on to experience full-blown strokes within three months.
A group of recipients of cadaver-derived human growth hormone (c-hGH) does not appear to be at increased risk for Alzheimer and Parkinson disease despite their likely exposure to neurodegenerative disease (ND)-associated proteins and elevated risk of infectious prion protein-related disease, according to a report published Online First by JAMA Neurology, a JAMA Network publication.
Researchers at the University of Iowa say the human brain has a new, second gatekeeper that registers fear. That region, likely the brainstem, signals fear from internal dangers. The finding could lead to more precise treatment for people suffering from panic attacks and other anxiety disorders. Results appear in Nature Neuroscience.
Sixteen new breakfast clinics, four new practical clinics and an expanded Sunday program are among the educational opportunities neurosurgical practitioners will have at the 81st AANS Annual Scientific Meeting in New Orleans, Louisiana from April 27-May 1, 2013.
A new approach to delivering therapeutics could lead to better treatment of central nervous system disorders. The work will be presented at the 57th Annual Meeting of the Biophysical Society (BPS), held Feb. 2-6, 2013, in Philadelphia, Pa.
Medical illustrators and neurological imaging experts at Johns Hopkins have figured out how night-hunting owls can almost fully rotate their heads - by as much as 270 degrees in either direction - without damaging the delicate blood vessels in their necks and heads, and without cutting off blood supply to their brains.
Being obese may increase the risk of developing multiple sclerosis (MS) in children and teenage girls, according to new research published in the January 30, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Findings offer a better understanding of the development and progression of multiple sclerosis and potential future therapeutic target.
The “July Effect” -- the notion that the influx of new residents and fellows at teaching hospitals each July makes that the worse time of year to be a patient -- seems to be a myth, according to new Mayo Clinic research that examined nearly 1 million hospitalizations for patients undergoing spine surgery from 2001 to 2008. Among those going under the knife, researchers discovered that the month surgery occurred had an insignificant impact on patient outcomes.
Cardiac disease is associated with increased risk of mild cognitive impairment such as problems with language, thinking and judgment -- particularly among women with heart disease, a Mayo Clinic study shows.
In experiments on rats outfitted with tiny goggles, scientists say they have learned that the brain’s initial vision processing center not only relays visual stimuli, but also can “learn” time intervals and create specifically timed expectations of future rewards. The research sheds new light on learning and memory-making, the investigators say, and could help explain why people with Alzheimer’s disease have trouble remembering recent events.
A new study suggests that triggers for migraine with aura may not be as strong as some people think. The research is published in the January 23, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology. Auras that occur with migraine include visual disturbances, with symptoms such as flashing lights or wavy lines.
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