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Alzheimer's and Dementia

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Seth Margolis, Alzheimer’s, ephexin5 , Brain, Amyloid

Protein That Regulates Brain Cell Connections Could Be New Target for Treating Alzheimer's Disease

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In experiments with a protein called Ephexin5 that appears to be elevated in the brain cells of Alzheimer's disease patients and mouse models of the disease, Johns Hopkins researchers say removing it prevents animals from developing Alzheimer's characteristic memory losses. In a report on the studies, published online March 27 in The Journal of Clinical Investigation, the researchers say the findings could eventually advance development of drugs that target Ephexin5 to prevent or treat symptoms of the disorder.

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Diabetes, insulin spray, Insulin, Cognitive Decline, Mild Cognitive Impairment, Memory, Aging, Alzheimer's Disease

Sniffing Out a New Strategy Against Alzheimer’s Disease

Neurologists at the Rush Alzheimer’s Disease Center are conducting an 18-month clinical trial testing a type of insulin delivered in a nasal spray – which is used to treat diabetes in some patients – in the Study of Nasal Insulin to Fight Forgetfulness (SNIFF).

Medicine

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Alzheimber's Disease, Dementia

Gene Discovered Associated with Tau Pathology

Investigators at Rush University Medical Center and the Brigham and Women’s Hospital in Boston reported the discovery of a new gene that is associated with susceptibility to a common form of brain pathology called Tau that accumulates in several different conditions, including Alzheimer’s disease, certain forms of dementia and Parkinsonian syndromes as well as chronic traumatic encephalopathy that occurs with repeated head injuries.

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California Researchers Awarded $100,000 Potamkin Prize for Dementia Research

The American Academy of Neurology is awarding two California researchers the 2017 Potamkin Prize for Research in Pick’s, Alzheimer’s and Related Diseases for their work in dementia research. Claudia Kawas, MD, of the University of California, Irvine, and Kristine Yaffe, MD, of the University of California, San Francisco, both members of the American Academy of Neurology, will be honored at the American Academy of Neurology’s 69th Annual Meeting in Boston.

Science

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Alzheimber's Disease, Neurochemistry

Researchers Focus on Cell Membranes to Develop Alzheimer's Treatments

Thin parts of the cell membranes of neurons turn out to be particularly vulnerable to a protein that collects in the brain of people with Alzheimer's disease, according to a University of Michigan researcher.

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Pavlovian response, NEURON ACTIVITY, Alzheimer's Disease, Parkinson's Disease, Tourette Syndrome, Learning

Study Identifies Brain Cells Involved in Pavlovian Response

UCLA scientists have traced the Pavlovian response to a small cluster of brain cells -- the same neurons that go awry during Huntington’s disease, Parkinson’s disease and Tourette syndrome. The research could one day help scientists find new approaches to diagnosing and treating these neurological disorders.

Medicine

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Alzheimber's Disease, Genetics, Neurology, Epidemiology, genetic assessment, polygenic hazard score

Genetic Assessment Developed to Determine Risk for Age-Associated Alzheimer’s Disease

An international team of scientists, led by researchers at University of California San Diego School of Medicine and University of California San Francisco, has developed a novel genetic score that allows individuals to calculate their age-specific risk of developing Alzheimer’s disease (AD), based upon genetic information.

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Tea, Aging, Ageing, neurocognitive disorders, Cohort Study

NUS Study: Daily Consumption of Tea Protects the Elderly From Cognitive Decline

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A study led by Assistant Professor Feng Lei from National University of Singapore’s Yong Loo Lin School of Medicine has found that regular consumption of tea lowers the risk of cognitive decline in the elderly, and this is especially so for APOE e4 gene carriers who are genetically at risk of developing Alzheimer’s disease.

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Neurosceince, Brain Awareness Week, Brain, molecular science, Dementia, Alzheimer Disease & Associated Disorders, Research, Autism, Neurological Diseases, Human Behavior, Mental Illness, Experts

FAU’s Brain Institute Commemorates ‘Brain Awareness Week’

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From human behavior such as mother/infant bonding, addiction and communication disorders to devastating brain diseases like Parkinson’s and Alzheimer’s disease, neuroscientists and other researchers from FAU’s Brain Institute are at the forefront of innovative research that will generate knowledge to benefit society.

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Dementia, Orthostatic Hypotension, Dizziness

Rapid Blood Pressure Drops in Middle Age Linked to Dementia in Old Age

Middle-aged people who experience temporary blood pressure drops that often cause dizziness upon standing up may be at an increased risk of developing cognitive decline and dementia 20 years later, new Johns Hopkins Bloomberg School of Public Health research suggests.







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