Feature Channels:

Alzheimer's and Dementia

Add to Favorites | Subscribe | Share

Filters:

  • (Press "esc" to clear)

Medicine

Channels:

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 5-Oct-2016 4:00 PM EDT

Medicine

Channels:

Alzheimer's Disease, Georgetown University Medical Center, Howard Fillit, Nilotinib, repurposing cancer drugs, R. Scott Turner, Chronic Myeloid Leukemia, Cognitive Impairment, Neuroinflammation, misfiled proteins, atophagy, plaques and tangles, tau, beta-amyloid, Charbel Moussa, Georgetown Memory Disorders Program, anti-neurodegenerative drug, Georgetown U

New Clinical Trial Will Test Cancer Drug as Alzheimer’s Treatment

ADDFlogo.jpg

The Alzheimer’s Drug Discovery Foundation (ADDF) announces a $2.1 million grant awarded to R. Scott Turner, MD, PhD, of Georgetown University Medical Center to conduct a phase II clinical trial of low-dose nilotinib (marketed as Tasigna® for use as a cancer therapy) in patients with Alzheimer’s disease.

Medicine

Channels:

Alzheimers disease, Food And Drug Administration, Nilotinib, Phase II clinical trial, randomized clinical trial

Georgetown Receives FDA Clearance to Conduct Clinical Trial with Nilotinib in Alzheimer’s Disease

Alzsmaller_1.jpg

Georgetown University Medical Center today announces the U.S. Food and Drug Administration has completed its review of an investigational new drug application (IND) for the use of nilotinib in a phase II clinical trial for patients with mild to moderate Alzheimer’s disease.

Medicine

Channels:

Occupational Therapy, Dementia, Caregiver, Family-centered care

In the Eye of the Beholder: First-of-Its-Kind Tool Measures Caregiver’s Perception of Capabilities of Person with Dementia

Piersolcardsort3.JPG

Comprehensive occupational therapy care requires a family-centered approach including treatment for the person with dementia and education for the caregiver. Clinical assessments exist to evaluate the capabilities of a person with dementia, but until now, occupational therapists did not have a validated instrument to gain understanding of the caregiver’s perceptions of the person with dementia’s abilities. Occupational therapist researchers at the Jefferson College of Health Professions at Thomas Jefferson University developed a first-of-its-kind tool to close this gap and published their findings in OTJR: Occupation, Participation and Health.

Medicine

Channels:

LBD, Lewy Body Dementia, Dementia, LBDA, Research

LBDA‘s New White Paper Explores the State of the Science and the Unprecedented Opportunity to Advance the Understanding and Treating Lewy Body Dementia

The Lewy Body Dementia Association (LBDA) announced a new white paper that explores the state of the science for the most misdiagnosed form of dementia. The white paper was developed to create an awareness that there are increasing research opportunities to gain critical insights into LBD.

Medicine

Channels:

alzheimer disease

Wake Forest Baptist Gets Federal Grant for Alzheimer’s Research Center

The National Institutes of Health (NIH) has awarded Wake Forest Baptist Medical Center a grant worth an estimated $8.7 million over five years for the establishment of a new center for research into Alzheimer’s disease.

Life

Arts and Humanities

Channels:

LBD, LBDA, Dementia, LEWY

LBDA Shines a Light on Lewy Body Dementia During October’s Lewy Body Awareness Month

To drive awareness of a common but little-known dementia, Lewy body dementia (LBD), the Lewy Body Dementia Association and families across the nation stand together in solidarity, making October, Lewy Body Awareness Month.

Science

Channels:

Biology, Parkinson Disease, Parkinson's Disease, Cell Biology, ALS, Alzheimer's Disease, Neurodegenative Disease

Parkinson's Disease Protection May Begin in the Gut

gutb-illo-640w.jpg

The gut may play a key role in preventing the onset of Parkinson's disease. UI biologists found that in roundworms, an immune response from intestinal cells sparks a series of chemical signals that ultimately preserves neurons whose death is associated with Parkinson's. The results appear in the journal Cell Reports.

Medicine

Channels:

TTUHSC El Paso, Texas Tech University Health Sciences Center El Paso, Ricardo , Geriatric Psychiatry, Alzheimer's Disease, neuropsychiatric symptoms, Depression, Agitation, elation, Hallucinations, Delusions, TARCC, NPI-Q, Neuropsychiatric Inventory Questionnaire, Hispanic, Mexican American

Study Finds Alzheimer’s Manifests Differently in Hispanics

Behavioral_Alzheimer_s_Symptoms_in_Hispanics.jpg

EL PASO, Texas - Certain symptoms associated with the development of Alzheimer’s disease, including agitation and depression, affect Hispanics more frequently and severely than other ethnicities. The findings, published in the Journal of Neuropsychiatry and Clinical Neuroscience (JNCN), suggest that Alzheimer’s disease manifests itself differently in Hispanic populations.

Medicine

Channels:

Nicotine, Smoking, Texas A&M Health Science Center

Can Nicotine Protect The Aging Brain?

Nicotine.jpg

Everyone knows that tobacco products are bad for your health. However, according to research at Texas A&M, it turns out the nicotine itself—when given independently from tobacco—could help protect the brain as it ages, and even ward off Parkinson’s or Alzheimer’s disease.

Medicine

Channels:

Alzheimer, alzheimer disease, Neurology, Brain, Gene

Genetic ‘Switch’ Identified as Potential Target for Alzheimer’s Disease

newsliderFestinstein.jpg

A team at the MRC Clinical Sciences Centre (CSC), based at Imperial College London, has found an important part of the machinery that switches on a gene known to protect against Alzheimer’s Disease.

Science

Channels:

Amyloid Beta, Alzheimers disease

The Shape-Shifting Protein Behind Alzheimer’s Disease

bieschke-CSMB.jpeg

New research from Washington University in St. Louis shows that the protein behind Alzheimer’s disease shape-shifts, changing its internal structure in order to infiltrate brain cells and become toxic.

Medicine

Channels:

alzheimer disease, Dementia, Wayne State University, Neuroscience, Gerontology, National Institues Of Health, National Institute On Aging, Institute of Gerontology

Wayne State Receives $3.6 Million NIH Grant to Advance Understanding of Alzheimer’s and Other Dementias

Raz_Naftali_RAZ_082616_01_MJ.jpg

Wayne State University has received a $3.6 million grant from the National Institute on Aging of the National Institutes of Health for a project that will advance knowledge of brain aging, its relation to cognitive performance and the role of common vascular and metabolic risk factors in shaping the trajectories of aging. The funded project extends the longitudinal study of healthy volunteers from the metro Detroit area.

Medicine

Channels:

Alzheimer's Disease, D. Martin Watterson, central nervous system, Drug Discovery, Northwestern University Feinberg School of Medicine, Biotechnology, Pharmaceutical, Neuroinflammation, Neurological Disorders, MW151, MW189, Clinical Trials, preclinical research, MWRD, Synapses, TBI in the military, Ms 275, MS

Dr. D. Martin Watterson Wins Alzheimer's Drug Discovery Foundation's Second Melvin R. Goodes Prize for Excellence in Alzheimer's Drug Discovery

GoodesPrizeLogo.jpg

Medicinal chemist and pharmacologist Daniel Martin Watterson, PhD, has been named the second annual winner of the Alzheimer’s Drug Discovery Foundation’s (ADDF) Melvin R. Goodes Prize for Excellence in Alzheimer’s Drug Discovery. The prize is the first to specifically recognize researchers working in promising areas of drug discovery for Alzheimer’s disease and related dementias. Dr. Watterson is the John G. Searle Professor of Molecular Biology and Biochemistry and Professor of Pharmacology at Northwestern University’s Feinberg School of Medicine. He also serves in an advisory role to pharmaceutical and biotechnology companies.

Medicine

Channels:

Disclosure, Alzheimer’s disease, ApoE genotype, biomarkers, Amyloid

How Do You Tell a Cognitively Normal Person They Will Likely Get Alzheimer’s in the Next Few Years?

As researchers seek cognitively normal people on the way to Alzheimer’s to fill clinical prevention trials, they face the delicate task of disclosing a highly elevated, but not certain, risk of developing the disease to thousands of people. Scientists look to cancer research for cues as they recruit for the first of such trials.

Medicine

Channels:

tracking sensor, Army, Dementia, Fitbit, training tool, GPS

Wearable Tracker Keeps Tabs on Patients, Soldiers

Dewearabledevice9-1-16.jpg

Wearable sensing device tracks movements, ambient environment, bio-signals and more.

Life

Social and Behavioral Sciences

Channels:

Dementia, Elderly, Sedentary, Activity, Emotional State, Rehabilitation, chair sensors

‘Care Chair’ Helps Detect Patients’ Movements, Mental State

DeCareChair8-31-16.jpg

Missouri S&T researchers create chair that detects daily behavior and mental state of elderly patients or those subject to dementia.

Medicine

Channels:

Aging, alzhiemer's disease, Medicine And Health, Memory & Cognitive Processes, Neurochemistry, Stress and Anxiety, Trauma Injury

First Study Examines PTSD & Cognitive Impairment in World Trade Center Responders

New research published by the journal Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring confirms the connection between posttraumatic stress disorder (PTSD) and cognitive impairment - in this case, among those who helped with search, rescue and cleanup efforts following the 2001 World Trade Center (WTC) attacks.

Medicine

Channels:

alzheimer disease, Neurology

Vesicles That Trap Amyloid Appear to Also Contribute to Alzheimer's

122795_web1.jpg

AUGUSTA, Ga. (Aug. 29, 2016) - Vesicles, fluid-filled sacs that brain cells make to trap amyloid, a hallmark of Alzheimer's, appear to also contribute to the disease, scientists report.

Medicine

Channels:

Atheroclerosis, Cardiovascular Disease, High Blood Pressure, Amyloid Beta, Alzheimer's, Dementia, Physiology

Stiff Arteries Linked with Memory Problems, Mouse Study Suggests

Using a new mouse model, researchers have found that stiffer arteries can also negatively affect memory and other critical brain processes. The findings, which may eventually reveal how arterial stiffness leads to Alzheimer’s and other diseases involving dementia, will be presented at the American Physiological Society’s Inflammation, Immunity and Cardiovascular Disease conference.







Chat now!