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Article ID: 697551

New Coalition of Philanthropists Including Bill Gates and Leonard Lauder Commit More Than $30 Million to Develop New Tools to Diagnose Alzheimer's Disease

Alzheimer's Drug Discovery Foundation

Philanthropist Bill Gates and the Alzheimer's Drug Discovery Foundation (ADDF) co-founder Leonard Lauder have announced a new initiative, Diagnostics Accelerator, to develop novel biomarkers for the early detection of Alzheimer's disease and related dementias.

Released:
17-Jul-2018 1:20 PM EDT
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Article ID: 697481

Majority of Older Adults with Probable Dementia Are Likely Unaware They Have It, Study Suggests

Johns Hopkins Medicine

A Johns Hopkins Medicine analysis of information gathered for an ongoing and federally sponsored study of aging and disability adds to evidence that a substantial majority of older adults with probable dementia in the United States have never been professionally diagnosed or are unaware they have been.

Released:
17-Jul-2018 8:00 AM EDT
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Embargo will expire:
18-Jul-2018 4:00 PM EDT
Released to reporters:
13-Jul-2018 3:55 PM EDT

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A reporter's PressPass is required to access this story until the embargo expires on 18-Jul-2018 4:00 PM EDT

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Article ID: 697413

Aphasia: A Disruption in Communication

LifeBridge Health

Most people who are familiar with the term associate it with stroke (i.e., brain damage caused by disrupted blood flow to the brain). But aphasia, an impairment of language, is not always caused by stroke.

Released:
13-Jul-2018 1:05 PM EDT
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Article ID: 697372

Novel Therapy Delays Muscle Atrophy in Lou Gehrig’s Disease Model

Case Western Reserve University

Supplementing a single protein found in the spinal cord could help prevent symptoms of Lou Gehrig’s disease, according to a new study out of Case Western Reserve University School of Medicine. Researchers found high levels of the protein—called mitofusion 2 or Mfn2—prevented nerve degeneration, muscle atrophy, and paralysis in a mouse model of the disease. Since Mfn2 is often depleted during Lou Gehrig’s, the new study suggests supplementing it could be a novel therapeutic approach for the disease.

Released:
12-Jul-2018 1:05 PM EDT
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Article ID: 697325

Practice Imperfect: Repeated Cognitive Testing Can Obscure Early Signs of Dementia

University of California San Diego Health

Alzheimer’s disease is a progressive, neurodegenerative condition that often begins with mild cognitive impairment (MCI), making early and repeated assessments of cognitive change crucial to diagnosis and treatment. In a paper in Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, researchers led by scientists at the University of California San Diego School of Medicine found that repeated testing of middle-age men produced a “practice effect” which obscured true cognitive decline and delayed detection of MCI.

Released:
11-Jul-2018 5:05 PM EDT
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  • Embargo expired:
    11-Jul-2018 4:00 PM EDT

Article ID: 697117

Higher Blood Pressure May Be Linked to Brain Disease, Alzheimer’s

American Academy of Neurology (AAN)

Older people who have higher blood pressure may have more signs of brain disease, specifically brain lesions, according to a study published in the July 11, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology. Researchers also found a link between higher blood pressure and more markers of Alzheimer’s disease, tangles in the brain.

Released:
6-Jul-2018 4:30 PM EDT
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Article ID: 697246

The ‘Big Bang’ of Alzheimer’s: Scientists ID genesis of disease, focus efforts on shape-shifting tau

UT Southwestern Medical Center

Scientists have discovered a “Big Bang” of Alzheimer’s disease – the precise point at which a healthy protein becomes toxic but has not yet formed deadly tangles in the brain.

Released:
10-Jul-2018 2:05 PM EDT
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Article ID: 697201

Vitamin D No Defence Against Dementia

University of Adelaide

New research from South Australian scientists has shown that vitamin D (also commonly known as the sunshine vitamin) is unlikely to protect individuals from multiple sclerosis, Parkinson’s disease, Alzheimer’s disease or other brain-related disorders.

Released:
10-Jul-2018 3:05 AM EDT
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Article ID: 697016

Rethinking Neurodegenerative Disease Treatment: Target Multiple Pathological Proteins, Not Just One

Perelman School of Medicine at the University of Pennsylvania

Nearly all major neurodegenerative diseases are defined by the presence of one of four proteins that have gone rogue. As such, investigational drugs aimed at preventing or slowing the disease often hone in on just one of these proteins. However, targeting multiple proteins at once may be the real key, according to a recent Penn Medicine study.

Released:
5-Jul-2018 9:20 AM EDT
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