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Scientists Establish that Drug Candidates Can Block Pathway Associated with Cell Death in Parkinson’s Disease

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In a pair of related studies, scientists from the Florida campus of The Scripps Research Institute have shown their drug candidates can target biological pathways involved in the destruction of brain cells in Parkinson's disease.

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Research Suggests Anti-Inflammatory Protein May Trigger Plaque in Alzheimer’s Disease

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Inflammation has long been studied in Alzheimer’s, but in a counterintuitive finding reported in a new paper, University of Florida researchers have uncovered the mechanism by which anti-inflammatory processes may trigger the disease.

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Study Detailing Axonal Death Pathway May Provide Drug Targets for Neurodegenerative Diseases

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Axons connect neurons with each other to form the neural networks that underpin the vital functions of perception, motility, cognition, and memory. In many neurodegenerative disorders, from traumatic injury or toxic damage to diseases such as Alzheimer’s or Parkinson’s disease, axonal degeneration represents an essential pathological feature.

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When Parkinsonism Does Not Mean Parkinson’s

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Lewy body dementia: often misdiagnosed as Parkinson’s disease.

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Depression, Behavior Changes May Start in Alzheimer’s Even Before Memory Changes

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Depression and other behavior changes may show up in people who will later develop Alzheimer’s disease even before they start having memory problems, according to a new study published in the January 14, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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Depression, Behavioral Changes May Precede Memory Loss in Alzheimer’s

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Depression and behavioral changes may occur before memory declines in people who will go on to develop Alzheimer’s disease, according to new research at Washington University School of Medicine in St. Louis.

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Coenzyme A Plays Leading Role in Nitric Oxide Function So Essential to Cell Metabolism

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Case Western Reserve and University Hospitals (UH) Case Medical Center researchers and physicians have discovered that the molecule known as coenzyme A plays a key role in cell metabolism by regulating the actions of nitric oxide. Their findings appeared in the Dec. 15 edition of the Proceedings of the National Academy of Sciences (PNAS).

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Curcumin’s Ability to Fight Alzheimer’s Studied

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One of the most promising new treatments for Alzheimer’s disease may already be in your kitchen. Curcumin, a natural product found in the spice turmeric, has been used by many Asian cultures for centuries, and a new study indicates a close chemical analog of curcumin has properties that may make it useful as a treatment for the brain disease.

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Nasal Spray with Insulin Equivalent Shows Promise as Treatment for Adults with Mild Cognitive Impairment, Alzheimer’s Dementia

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A man-made form of insulin delivered by nasal spray may improve working memory and other mental capabilities in adults with mild cognitive impairment and Alzheimer’s disease dementia, according to a pilot study led by researchers at Wake Forest Baptist Medical Center.

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Brain Scientists Figure Out How A Protein Crucial To Learning And Memory Works

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Researchers at Johns Hopkins have found out how a protein crucial to learning works: by removing a biochemical “clamp” that prevents connections between nerve cells in the brain from growing stronger. The finding moves neuroscientists a step closer to figuring out how learning and memory work, and how problems with them can arise.