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Science

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Alzheimer's Disease, Blood Brain Barrier, neurotrophic growth factor, Jagdish Singh, NDSU Research, Nerve Growth Factor, Gene Therapy, Pharmaceutical Sciences, Dementia

NDSU Researcher Awarded $1.89 Million Grant for Alzheimer’s Study

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Jagdish Singh, chair and professor of pharmaceutical sciences at North Dakota State University, is receiving a $1.89 million grant award for his research to develop a nanotechnology-based system that effectively delivers Nerve Growth Factor across the blood brain barrier to treat Alzheimer's disease.

Medicine

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University of Pennsylvania School of Nursing, Penn Nursing Science, Penn Nursing, Nancy Hodgson, Dementia, Palliative Care, Alzheimer's Disease, Health Policy, health ethics, AMA Journal of Ethics

New Article by Penn Nursing Professor Examines Moral Obligation of Clinicians to Address the Needs of Family Caregivers of Persons with Dementia

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More than 15 million family members and other unpaid caregivers provide care to persons living with dementia in the United States. Yet the current healthcare environment and reimbursement models emphasize obligations toward individual patients, preventing clinicians from reaching out to these caregivers to assess their needs and provide care.

Medicine

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 7-Dec-2016 4:00 PM EST

Medicine

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Alzheimer's research, Amyloid

Ronald Petersen, M.D., Ph.D., Discusses Future of Alzheimer’s Research After Drug Trial Fails

Eli Lilly’s Phase III drug trial attempting to slow the advancement of Alzheimer’s disease disappointed many when it recently was announced that the study did not meet its primary endpoints.

Medicine

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GAIT, Rochester Epidemiology Project, High Altitude and Harsh Environments Medical Clinic, Bleeding, Multiple Myeloma

Mayo Clinic Monthly News Tips — November 2016

Mayo Clinic Monthly News Tips — November 2016

Medicine

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Alzheimer's Disease, Dementia, Einstein Aging Study, Aging Brain, Aging, Neurology, Healthy Aging, smartphones and dementia

Einstein and Penn State Researchers Awarded $12.2 Million to Study Alzheimer's Disease

December 1, 2016 — (BRONX, NY) —The National Institutes of Health has awarded researchers at Albert Einstein College of Medicine and Pennsylvania State University a five-year, $12.2 million grant to continue studies on the aging brain, Alzheimer’s disease and other dementias. More than five million Americans are living with Alzheimer’s disease—a number that is expected to double by 2040 as baby boomers age.

Science

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Alzheimer's, Alzheimer's Disease, Gram-Negative Bacteria, Amyloid, Lipopolysaccharide, E Coli, Uc Davis, UC Davis Neurology, Neurology

Gram-Negative Bacteria May Influence Alzheimer’s Disease Pathology

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For the first time, researchers have found higher levels of Gram-negative bacteria antigens in brain samples from late-onset Alzheimer’s disease patients. Compared to controls, patients with Alzheimer's had much higher levels of lipopolysaccharide (LPS) and E coli K99 pili protein. In addition, The UC Davis team also found LPS molecules congregated with amyloid plaques, which have been linked to Alzheimer’s pathology and progression. The research was published today in the print edition of the journal Neurology.

Medicine

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Dr. Rodolfo Savica, GAIT, Mayo Clinic Study of Aging, Medical Research, Minnesota News Releases, news releases

Comparing Gait Parameters Can Predict Decline in Memory and Thinking

Walking is a milestone in development for toddlers, but it’s actually only one part of the complex cognitive task known as gait that includes everything from a person’s stride length to the accompanying swing of each arm. A Mayo Clinic study recently published in the Journal of Alzheimer’s Disease found that problems associated with gait can predict a significant decline in memory and thinking.

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Parkinson's Disease, Gene Mutation

Gene Mutation Linked to Early Onset of Parkinson’s Disease in Caucasians

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A defect in a gene that produces dopamine in the brain appears to accelerate the onset of Parkinson’s disease, according to new research from Iowa State University. The effect is particularly dramatic for young-to-middle-age adults.

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Huaxi Xu, Ph.D., Named the Jeanne and Gary Herberger Chair in Neuroscience at SBP

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Sanford Burnham Prebys Medical Discovery Institute (SBP) has announced that Huaxi Xu, Ph.D., has been named the Jeanne and Gary Herberger Leadership Chair in Neuroscience at the institute.

Medicine

Science

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nucelation, phase transition, Matter, thermodynamic phases, nucleation process, Oligomers, Anđela Šarić, Thomas C. T. Michaels, Alessio Zaccone, Tuomas P.J. Knowles, Daan Frenkel, University College London, University Of Cambridge, Harvard University, The Journal Of Chemical Physics

From Champagne Bubbles, Dance Parties and Disease to New Nanomaterials

Nucleation processes are a first step in the structural rearrangement involved in the phase transition of matter: a liquid morphing into a gas, a gas becoming a liquid and so on. Understanding this process is critical for preventing, halting or treating cases of nucleation processes gone wrong -- such as in human disease. Now, a team of researchers have made headway toward understanding this problem from a molecular point of view in a new study, which they discuss in this week’s The Journal of Chemical Physics.

Medicine

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Alzheimer, alzheimer disease, Alzheimer's, Alzheimer's Disease, Alzheimer's disease, dementia, Caregiver, Caregiver Burden, Caregiver Coping, Caregiver Depression, caregiver health tips, Caregiving, caregiving tips, Holiday, Holiday Advice, holiday burnout, Holidays, holidays family , holidays, Christmas, perfectionism, party planning, , Memory, holiday tra

5 Tips to Help Alzheimer’s Families Have Happier Holidays

Dealing with Alzheimer’s disease can be difficult any time of year, but the holidays present unique challenges for patients and their families.

Medicine

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Alzheimers disease, Dementia, Alzheimer's, Amyloid, Neuroscience, Biochemistry, brain blood vessel, Cognitive Impairment

Unique Structure of Brain Blood Vessel Amyloid Latest Clue to Alzheimer’s Development?

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A team of neuroscience and biochemistry researchers at Stony Brook University have made a novel discovery that illustrates for the first time the difference between amyloid buildup in brain blood vessels and amyloid buildup around brain neurons.

Medicine

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Dementia, alzheimer disease, Alzheimer, Healthy Lifestyle, Exercise, Diet

Dementia Rates Declining Thanks to Healthier Living According to University of Louisville Aging Expert

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Medicine

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Dementia, Alzheimer

Dementia on the Downslide, Especially Among People with More Education, Study Finds

In a hopeful sign for the health of the nation’s brains, the percentage of American seniors with dementia is dropping, a new study finds. The downward trend has emerged despite something else the study shows: a rising tide of three factors that are thought to raise dementia risk by interfering with brain blood flow, namely diabetes, high blood pressure and obesity.

Medicine

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Northwestern University, Alzheimer's, Brain, Research

Elderly Discovered with Superior Memory and Alzheimer’s Pathology

New Northwestern Medicine research on the brains of individuals 90 years and older who had superior memories until their deaths revealed widespread and dense Alzheimer’s plaques and tangles in some cases, considered full-blown Alzheimer’s pathology.

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alzheimer disease

More Human-Like Model of Alzheimer’s Better Mirrors Tangles in the Brain

A new animal model developed at Penn Medicine using tau tangles isolated from the brains of Alzheimer’s patients rather than synthetic tau tangles paints a closer picture of the tau pathology in the AD brain

Medicine

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Alzheimer Disease & Associated Disorders, Cognitive Decline, Forgetfullness, Holidays

Forgetfulness or Alzheimer's?

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The holidays are a time when families get together -- sometimes after long periods apart. But sometimes seldom-seen elderly family members show signs of worrisome mental decline. When should family members be concerned about the possibility of Alzheimer's?

Medicine

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atrial fibrillation (AF), Dementia, intermountain medical center, American Heart Association, american heart association scientific sessions, Warfarin, Blood Clots, Medication, Heart Patients, Research & Development, Cardiovascular Research, intermountain healthcare, Jared Bunch, MD

Atrial Fibrillation Patients Are at Increased Risk of Dementia, Regardless of Anticoagulation Use

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Atrial fibrillation patients who use the drug, warfarin, to prevent harmful blood clots from forming in their hearts to lower risk of stroke are at higher risk of developing dementia than patients who use warfarin for non-atrial fibrillation conditions, according to a new study from the Intermountain Medical Center Heart Institute.

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Study to Explore Detection of Learning Disabilities Through Physical Movement

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An Indiana University physicist and neuroscientist who studies how physical movement can be used to detect autism in children and adults has received support from the National Science Foundation. The $750,000 NSF grant to IU scientist Jorge V. José and collaborators will be used to apply analytical methods pioneered at IU and Rutgers University toward diagnosing, and possibly treating, a wider range of learning disabilities.







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