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Researchers Develop Novel Drug That Reverses Loss of Brain Connections in Models of Alzheimer’s

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NitroMemantine is the first drug to halt the progression of synaptic loss and to even restore these connections between nerve cells. The combination drug is now headed for clinical trials.

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Alzheimer's Brain Change Measured in Humans

Scientists have measured a significant and potentially pivotal difference between the brains of patients with an inherited form of Alzheimer’s disease and healthy family members who do not carry a mutation for the disease.

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Commonly-Prescribed Drugs May Influence the Onset and Progression of Alzheimer’s Disease

Multiple drug classes commonly prescribed for common medical conditions are capable of influencing the onset and progression of Alzheimer’s disease.

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Life

Social and Behavioral Sciences

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Better Care for People with Dementia: New UMDNJ YouTube Channel Helps Family and Professional Caregivers

People afflicted with Alzheimer’s disease and other forms of dementia have a profound need for harmony and often exhibit behavioral issues when they are experiencing internal chaos. To assist caregivers—both family and professional—with creating an atmosphere of harmony, the staff at the Comprehensive Services on Aging (COPSA) Institute for Alzheimer’s Disease and Related Disorders at the University of Medicine and Dentistry of New Jersey has produced a series of free educational videos, available on the COPSAEducation YouTube channel (http://bit.ly/13YCWUD)

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JHU, Michigan to Develop Dementia Tool for Caregivers

$1.7M NIH collaborative grant backs researchers' work on web-based WeCare, which will help caregivers better understand, assess, and treat behavioral changes in those with dementia.

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Rapid, Irregular Heartbeat May Be Linked to Problems with Memory and Thinking

People who develop a type of irregular heartbeat common in old age called atrial fibrillation may also be more likely to develop problems with memory and thinking, according to new research published in the June 5, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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Healthy Lifestyle Choices Mean Fewer Memory Complaints, Poll by UCLA and Gallup Finds

Research has shown that healthy behaviors are associated with a lower risk of Alzheimer's disease and dementia, but less is known about the potential link between positive lifestyle choices and milder memory complaints, especially those that occur earlier in life and could be the first indicators of later problems.

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New Mayo Clinic Approach Could Lead to Blood Test to Diagnose Alzheimer’s in Earliest Stage

Blood offers promise as a way to detect Alzheimer’s disease at its earliest onset, Mayo Clinic researchers say. They envision a test that would detect distinct metabolic signatures in blood plasma that are synonymous with the disease -- years before patients begin showing cognitive decline. Their study was recently published online in the journal PLOS ONE.

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Science

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Preventing ‘Traffic Jams’ in Brain Cells

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An Alzheimer’s disease protein controls the speed at which materials move through brain cells, and defects could lead to deadly pileups of the kind seen in neurodegenerative disease, a new publication finds.

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Multiple Research Teams Unable to Confirm High-Profile Alzheimer’s Study

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Teams of highly respected Alzheimer’s researchers failed to replicate what appeared to be breakthrough results for the treatment of this brain disease when they were published last year in the journal Science.

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