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Some Anti-Inflammatory Drugs Affect More Than Their Targets

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Researchers have discovered that three commonly used nonsteroidal anti-inflammatory drugs, or NSAIDs, alter the activity of enzymes within cell membranes. Their finding suggests that, if taken at higher-than-approved doses and/or for long periods of time, these prescription-level NSAIDs and other drugs that affect the membrane may produce wide-ranging and unwanted side effects.

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Investigational Therapy Focuses on Slowing Progression in Mild to Moderate Alzheimer’s

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Patients with mild to moderate Alzheimer’s disease currently have no treatment options to slow brain cell deterioration. Researchers at Houston Methodist’s Nantz National Alzheimer Center are studying an investigational drug that proposes to do just that.

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National Health Organization Offers Answers to “Lewy Who?” Five Ways to Fight Lewy Body Dementia

Today, the Lewy Body Dementia Association (LBDA) steps up its awareness and fundraising effort “Lewy Who?” to put the brakes on Lewy body dementia (LBD). With symptoms that resemble both Alzheimer’s and Parkinson’s disease, LBD is the most misdiagnosed form of dementia. Yet, following Alzheimer’s disease, it is the second most common cause of progressive dementia, affecting 1.3 million Americans. Families can fight this debilitating disease while educating others about LBD. LBDA offers five (5) ways to fight: (1) donate, (2) employer matching gifts, (3) plan a community event, (4) volunteer, or (5) partner with LBDA.

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New Non-Invasive Technique Controls Size of Molecules Penetrating the Blood-Brain Barrier

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A new technique developed by Elisa Konofagou, associate professor of biomedical engineering and radiology at Columbia Engineering, has demonstrated for the first time that the size of molecules penetrating the blood-brain barrier can be controlled using acoustic pressure—the pressure of an ultrasound beam—to let specific molecules through. This innovative method, published in the Journal of Cerebral Blood Flow & Metabolism, may help improve drug delivery to the brain.

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Most Misdiagnosed Form of Dementia Leaves Patients, Doctors Unprepared

Even though Lewy body dementia is second only to Alzheimer’s disease as the most common cause of progressive dementia, affecting 1.3 million Americans, the symptoms of LBD are not well recognized by many physicians, especially primary care physicians and other general practitioners. Unfortunately, then, most people are not diagnosed until they are at moderate or severe states, leaving their caregivers unprepared and the patient vulnerable to potentially deadly medication side effects.

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Study: Link Between Vitamin D and Dementia Risk Confirmed

In the largest study of its kind, researchers suggests that in older people, not getting enough vitamin D may double the risk of developing dementia and Alzheimer’s disease. The study is published in the August 6, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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Analysis of African Plant Reveals Possible Treatment for Aging Brain

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Salk scientists find that a plant used for centuries by healers of São Tomé e Príncipe holds lessons for modern medicine.

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How Is Depression Related to Dementia?

A new study gives insight into the relationship between depression and dementia. The study is published in the July 30, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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New Protein Structure Could Help Treat Alzheimer's, Related Diseases

University of Washington bioengineers have a designed a peptide structure that can stop the harmful changes of the body's normal proteins into a state that's linked to widespread diseases such as Alzheimer's, Parkinson's, heart disease, Type 2 diabetes and Lou Gehrig's disease.

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Major Advances in Alzheimer’s, Colon Cancer, Multiple Myeloma, and Sleep Apnea Testing, and in Maternal-Fetal Health Research to Be Highlighted at 2014 AACC Annual Meeting

The groundbreaking scientific studies featured at the 2014 AACC Annual Meeting & Clinical Lab Expo will include research on a blood test for Alzheimer’s that uses biochip technology, a new test to diagnose colon cancer early, a more accurate method for determining multiple myeloma prognosis, a less stressful test for sleep apnea, and the development of a bank of biospecimens from pregnant women that could prove crucial for women’s health research.

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