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AARDA Salutes July #Autoimmune Heroes for Spearheading National Leadership, Collaboration on Autoimmune Disease Research

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American Autoimmune Related Diseases Association (AARDA) announced today its July Autoimmune Heroes.

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New Research Studies Identify Potential Cause of and New Treatment for Autoimmune Diseases

The American Autoimmune Related Diseases Association, Inc. (AARDA) is spotlighting two new research studies originally reported in ScienceDaily.

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AARDA Rated “4-Star” Nonprofit by Charity Navigator

Recognizing the American Autoimmune Related Diseases Association, Inc’s (AARDA) strong financial health and commitment to accountability and transparency, Charity Navigator has awarded the organization its highest, 4-star rating for the seventh time in the last eight years.

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New Therapy Treats Autoimmune Disease Without Harming Normal Immunity

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In a study with potentially major implications for the future treatment of autoimmunity and related conditions, scientists have found a way to remove the subset of antibody-making cells that cause an autoimmune disease, without harming the rest of the immune system.

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AARDA Salutes June #Autoimmune Hero for Collaborative Research

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As part of its ongoing 25th Anniversary celebration, American Autoimmune Related Diseases Association (AARDA) announced today its June Autoimmune Hero – Johns Hopkins University’s Autoimmune Disease Research Center (ADRC).

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Researchers Discover Potential Genetic Trigger of Autoimmune Disease

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Researchers at Hospital for Special Surgery (HSS) have uncovered a potential genetic trigger of systemic autoimmune disease.

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Pilot Study Successfully Uses DNA Sequencing to Diagnose Brain Infections

In a proof-of-principle study, a team of physicians and bioinformatics experts at Johns Hopkins reports they were able to diagnose or rule out suspected brain infections using so called next-generation genetic sequencing of brain tissue samples.

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The Vasculitis Foundation 2016 Awareness Video

A short video produced by the Vasculitis Foundation to help raise awareness about vasculitis, a rare autoimmune disease. Also, the video promotes the non-profit, Vasculitis Foundation.

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Researchers Uncover New Mode of Action for HUMIRA in Rheumatoid Arthritis Patients

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Researchers from University College London have discovered that the widely used antiinflammatory drug HUMIRA doesn’t just work by inhibiting its target protein, TNF, but by enhancing a particular function of TNF in rheumatoid arthritis patients. The study, “Anti-TNF drives regulatory T cell expansion by paradoxically promoting membrane TNF–TNF-RII binding in rheumatoid arthritis,” which will be published online June 6 in The Journal of Experimental Medicine, may help explain the divergent efficacies of different TNF-targeting drugs.

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Vasculitis Foundation Announces Partnership with Olympic Hopeful and Vasculitis Patient Brandon Hudgins to Create Awareness of Autoimmune Vasculitis

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The Vasculitis Foundation (VF) is partnering with Olympic hopeful and vasculitis patient Brandon Hudgins to create Victory Over Vasculitis: VF Team Brandon." The initiative is designed to support Hudgins' efforts to increase awareness of his rare, autoimmune disease as he attempts to qualify for the United States Olympic Team.

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New Clues Found to Immune System’s Misfiring in Autoimmune Diseases

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Genetic master switches that turn the activity of specific types of immune cells up or down have been identified by researchers at Washington University School of Medicine in St. Louis. The regions of DNA that make up these switches include genetic variants linked to a range of autoimmune diseases.

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Sea Urchins Defy Aging, Study Identifies How Brain Connects Memories Across Time, Regular Exercise at Any Age Might Stave Off Alzheimer’s, and more in the Aging News Source

Click to visit the Aging Channel

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Study Reveals Protein That Dials Immune Responses Up and Down

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Research led by scientists at SBP has identified a new regulator of immune responses. The opens the door for a new approach to modulating T cell responses to treat infections, autoimmune diseases, and cancer.

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The Wistar Institute Tapped for Global, Women-Led Melanoma Research Team Funded by the Melanoma Research Alliance

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Wistar is part of global, women-led team awarded MRA grant to fund collaborative melanoma research

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Researchers Make a Key Discovery in How Malaria Evades the Immune System

The malaria parasite Plasmodium falciparum hijacks an immune system process to invade red blood cells, according to a study led by researchers at Penn State College of Medicine. Understanding how malaria invades the cells could lead to a more effective vaccine.

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Combining Radiation with Immunotherapy Showing Promise Against Melanoma

Combining radiation treatments with a new generation of immunotherapies is showing promise as a one-two-punch against melanoma, Loyola Medicine researchers report in a review article in the Journal of Radiation Oncology.

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U.S. Congresswoman Debbie Dingell Recognizes AARDA’s 25th Anniversary on the Floor of Congress

U.S. Congresswoman Debbie Dingell (D-Michigan) has recognized AARDA's 25th anniversary in The Congressional Record, praising the organization for its longstanding and tireless work on behalf of autoimmune disease patients everywhere.

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Top Stories 5-17-2016

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BIDMC Researchers Identify Enzyme That Contributes to Development of Lupus

Researchers at Beth Israel Deaconess Medical Center (BIDMC) have identified an enzyme that is significantly elevated in mouse models of systemic lupus erythematosus and in blood samples of patients with lupus. Published online today in The Journal of Clinical Investigation, the new findings demonstrate that inhibition of the SHP-2 enzyme can significantly diminish lupus symptoms – including skin lesions, enlarged spleen and kidney failure – and suggest that development of a SHP-2 inhibitor drug could offer a new therapeutic approach for this often debilitating disease.

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Top Stories 5-16-2016

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