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New Research Finds Pathogenic Connection between Autoimmune Disorders and Cancer

Autoimmune disorders may share certain pathogenic mechanisms with cancer, according to a new report published in PLOS ONE by Linda Kusner, Ph.D., assistant research professor in the Department of Pharmacology and Physiology at the George Washington University School of Medicine and Health Sciences.

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Crohn's Disease Research

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University of Delaware researchers have identified a protein, hiding in plain sight, that acts like a bodyguard to help protect and stabilize another key protein, that when unstable, is involved in Crohn’s disease. The fundamental research points to a possible pathway for developing novel therapies for the inflammatory bowel disease.

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Common Treatment of Certain Autoimmune Disease Does Not Appear Effective

Among patients with the systemic autoimmune disease primary Sjögren syndrome, use of hydroxychloroquine, the most frequently prescribed treatment for the disorder, did not improve symptoms during 24 weeks of treatment compared with placebo, according to a study in the July 16 issue of JAMA.

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An Alternative to Surgery for Graves’ Eye Disease

A low-carb, gluten-free diet with plenty of vegetables is helping a patient with Graves' eye disease to see normally again.

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Soothing Cells, Peaceful Protein Could Hold Promise for Treating Autoimmune Uveitis

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Uveitis occurs when immune cells invade the eye, causing inflammation, swelling and vision loss. Researchers at the National Eye Institute (NEI) have found a unique type of immune cell and a secreted protein that, in tests on mice, can protect against the disease.

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Stem Cell Transplantation For Severe Sclerosis Linked With Improved Long-term Survival

Among patients with a severe, life-threatening type of sclerosis, treatment with hematopoietic stem cell transplantation (HSCT), compared to intravenous infusion of the chemotherapeutic drug cyclophosphamide, was associated with an increased treatment-related risk of death in the first year, but better long-term survival, according to a study in the June 25 issue of JAMA.

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Penn Study Reveals a Common Genetic Link in Fatal Autoimmune Skin Disease

Autoimmune disease occurs when the body's own natural defense system rebels against itself. One example is pemphigus vulgaris (PV), a blistering skin disease in which autoantibodies attack desmoglein 3 (Dsg3), the protein that binds together skin cells. Researchers from the Perelman School of Medicine at the University of Pennsylvania recently found a shared genetic link in the autoimmune response among PV patients that provides important new clues about how autoantibodies in PV originate.

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“Strange Body” Offers Insight Into Managing Chronic Illnesses

What began as a letter to her two children about her experiences living with multiple autoimmune diseases, quickly morphed into a book by Donna Weir. “Strange Body: Common Autoimmune Disease Questions Answered” chronicles Weir’s life during the past decade as she struggled with ailments that often left her weak and combative. The book is on sale now and the royalties from digital downloads purchased through July 15 will be donated to the American Autoimmune Related Diseases Association (AARDA).

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Autoimmune Disease Association Hosts First Walk of 2014

The Washington DC area will Link Together For a Cure.

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Benaroya Research Institute Scientists Identify Drivers of Rheumatoid Arthritis

Researchers at Benaroya Research Institute at Virginia Mason (BRI) used cutting-edge tetramer technology developed at BRI to find the T cells that drive rheumatoid arthritis (RA).

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