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Researchers Discover 10 New Lupus Genes in Asian Population Study

An international coalition of researchers led by Oklahoma Medical Research Foundation scientist Swapan Nath, Ph.D., has identified 10 new genes associated with the autoimmune disease lupus. The findings were published in the Jan. 25 issue of Nature Genetics.

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New TSRI Study Shows Path to ‘Dial Down’ Autoimmunity Without Compromising Immune Response

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A new study led by scientists at The Scripps Research Institute shows how dangerous autoimmune responses, seen in diseases such as lupus and multiple sclerosis, might be “dialed down” without compromising the immune system’s ability to fight viruses and bacteria.

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Important Regulator of Immune System Decoded

Plasma cells play a key role in our immune system. Now scientists at the Research Institute of Molecular Pathology (IMP) in Vienna, Austria, and at the Walter and Eliza Hall Institute (WEHI) in Melbourne, Australia, succeeded in characterizing a central regulator of plasma cell function. The results of both teams are published in two back-to-back papers in “Nature Immunology” today.

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Bone Marrow Lesions Can Help Predict Rapidly Progressing Joint Disease

A new study from the Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, shows lesions, which can best be seen on MRI scans, could help identify individuals who are more likely to suffer from more rapidly progressing osteoarthritis.

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Researchers Find Link Between Processed Foods and Autoimmune Diseases

Researchers in Israel and Germany have identified a link between the increased use of processed foods and the rise in the incidence of autoimmune diseases.

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UGA Research Links Inorganic Mercury Exposure to Damaged Cell Processes

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University of Georgia research has found that inorganic mercury, which was previously thought to be a less harmful form of the toxic metal, is very damaging to key cell processes.

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The Leonard C. Goodman Institute for Investigative Reporting Is Now Accepting Submissions

The deadline for this round of proposals is January 15, 2016. Candidates will be notified of decisions by the end of February 2016. The Institute pays a competitive rate--and covers expenses--for investigative reporting that advances social and economic justice. All stories are published in In These Times magazine and on InTheseTimes.com.

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Diseases That Cause Rashes and Other Skin Problems Also Can Trigger Serious Neurological Conditions

Diseases such as lupus that cause rashes and other skin problems also can trigger migraine headaches, strokes and other serious neurological conditions, according to an article by Loyola University Medical Center physicians.

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Top Stories 11 Dec 2015; New Forensic Science Breakthroughs, Breast Cancer Treatment Difference by Age, Racial Disparities in Dialysis, and More...

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Virginia Tech Researchers Answer Perplexing Question About Lupus

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Biomedical researchers have suspected that a specific set of immune cells are responsible for causing disease in late-stage lupus patients, but until now they haven’t known for sure. An immunologist has found that these cells do not, in fact, contribute to late-stage lupus in mice.

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Nephrologists to Help Find Treatment for Lupus

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Nephrologists at Texas Tech University Health Science Center (TTUHSC) El Paso have been invited to participate in a national consortium that’s investigating the key causes of lupus nephritis — an autoimmune disease that can cause kidney failure.

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New Treatment Option May Be on the Horizon for Polymyalgia Rheumatica

A drug approved to treat rheumatoid arthritis, tocilizumab, yielded favorable results as a potential new therapy for patients with polymyalgia rheumatica in an open-label, phase II study at Hospital for Special Surgery.

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Complement Activation Predicts Pregnancy Complications in Women with Lupus

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Researchers at Hospital for Special Surgery have identified multiple clinical and biologic markers that correlate with adverse pregnancies, including, most recently, the activation of complement, a series of proteins that protect us from invading microbes.

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Deaths From Heart Disease Declining Among Rheumatoid Arthritis Patients

Rheumatoid arthritis patients are twice as likely as the average person to develop heart disease, but a new study shows that efforts to prevent heart problems and diagnose and treat heart disease early may be paying off. Despite the heightened danger, deaths from cardiovascular disease among people with rheumatoid arthritis are declining, the research found. The study was among Mayo Clinic research being presented at the American College of Rheumatology’s annual meeting in San Francisco.

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People with Rheumatoid Arthritis Who Change Anti-TNF Inhibitors for Non-Medical Reasons at Increased Risk for More Symptoms and Disease Activity

People with well-controlled rheumatoid arthritis who change anti-TNF inhibitors due to non-medical reasons — such as increased copay, change of insurance, job loss, or other economic factors — are at a higher risk to develop increased symptoms and higher disease activity as well as an increased utilization of health care resource use, according to new research findings presented this week at the American College of Rheumatology Annual Meeting in San Francisco.

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2-Year Clinical Trial Shows Joint Injections with Steroids Are Ineffective in Reducing Progression of Knee Osteoarthritis

Injections of corticosteroids in the knee joints appear to be safe, but not effective, according to the findings of a two-year clinical trial presented this week at the American College of Rheumatology Annual Meeting in San Francisco.

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Is Treat-to-Target Really Working for People with Rheumatoid Arthritis?

A new study, presented this week at the American College of Rheumatology Annual Meeting in San Francisco, shows that treating rheumatoid arthritis patients toward a target of remission or low disease activity works immediately and leads to higher remission rates.

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Body Mass Index May Be a Key to Achieving Sustained Remission in Early RA

Being overweight or obese can reduce the likelihood of achieving sustained remission of early rheumatoid arthritis, according to new research findings presented this week at the American College of Rheumatology Annual Meeting in San Francisco.

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Study Shows Lupus Support and Education Program Has Positive Impact

A study at Hospital for Special Surgery finds that a support group addressing the psychological and educational needs of people with lupus is a valuable resource to help them cope with the disease.

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The Innate Immune System Modulates the Severity of Multiple Sclerosis

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Multiple sclerosis, a debilitating neurological disease, is triggered by self-reactive T cells that successfully infiltrate the brain and spinal cord where they launch an aggressive autoimmune attack against myelin, the fatty substance that surrounds and insulates nerve fibers. In their latest study, published in the Nov. 2, 2015, advance online issue of Nature Immunology, researchers at the La Jolla Institute for Allergy and Immunology report that these disease-causing autoimmune T cells are lured into the nervous system by monocytes and macrophages, a subset of immune cells better known as the immune system’s cleanup crew.