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Autoimmune Diseases

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Science

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Metabolic Disease, Obesity, Diabetes, Nonalcoholic Fatty Liver Disease, Glucoccorticoids, Steroid Medication, Steroid Hormone Treatment, Autoimmune Disease, chronic inflammatory disease

Feast or Famine: The Switch That Helps Your Liver Adapt

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Scientists at the Sanford Burnham Prebys Medical Discovery Institute (SBP) have identified a previously unknown way that stress hormones (glucocorticoids) control genes in the liver to help the body adapt to the fasting state. The study, published today in Cell Metabolism, describes an obscure protein, SETDB2, that’s increased during times of fasting and alters the genome to help turn on genes needed to adjust to the absence of food.

Medicine

Channels:

Vasculitis, Vasculitis Foundation, VF, Wegener’s granulomatosis , Autoimmune vasculitis, Dr. Jeffrey Raines, Fairview Medical Center

Minnesota Obstetrician/Gynecologist Diagnoses Rare Disease; Receives the Vasculitis Foundation’s 2016 VF-RED Award

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Dr. Jeffrey Raines, a General Obstetrician/Gynecologist and supervisor for the Obstetric/Gynecology Department of Fairview Medical Group Fairview Medical Center in Maple Grove, Minnesota earned a special award for his critical early diagnosis of vasculitis.

Medicine

Channels:

Bacteriology, Microbiology, Infectious Diseases, Immunology, Inflammation, Autoimmune Disease, Rheumatoid Arthritis, Cytokines

Flesh-Eating Infections in Rheumatoid Arthritis Patients Spur New Discovery

Rheumatoid arthritis patients taking medications that inhibit interleukin-1beta (IL-1beta), a molecule that stimulates the immune system, are 300 times more likely to experience invasive Group A Streptococcal infections than patients not on the drug, according to University of California San Diego School of Medicine researchers. Their study, published August 19 in Science Immunology, also uncovers a critical new role for IL-1beta as the body’s independent early warning system for bacterial infections.

Medicine

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Vasculitis, Vasculitis Foundation, Churg-Strauss, Dr. Seth Sullivan, eosinophilic granulomatosis with polyangiitis (EGPA), rare disease, autoimmune disorder, Autoimmune Disease, Norwalk Hospital

Dr. Seth Sullivan Honored with Vasculitis Early Diagnosis Award

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Dr. Seth Sullivan was awarded the 2016 VF RED Award for his work in diagnosing a patient with vasculitis. The Vasculitis Foundation created the award to honor those medical professionals who have made an early diagnosis of the rare, autoimmune disease, thus improving the patient's outcome.

Medicine

Channels:

Lupus, Autoimmune Disease, Inflammation, Infection

Mouse Study Points Way to Shut Down Harmful Immune Response in Lupus

Molecules that scavenge debris from dying cells appear to halt the cycle of chronic inflammation in lupus, while also enhancing the body’s ability to combat flu, according to Duke Health studies in mice.

Medicine

Channels:

Vasculitis, Vasculitis Disease, VF, Vascultitis Foundation, Autoimmune Disease, rare disease

Medical Professionals Win Vasculitis Foundation Award for Early Diagnosis of Rare Disease

The Vasculitis Foundation awarded three doctors the 2016 V-RED Award for making an early diagnosis of vasculitis, a rare autoimmune disease.

Medicine

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Myositis, Polymyositis, Dermatomyositis, Inclusion Body Myositis, autoimmunde disorders, patient conference, physician symposium, myositis experts, myositis awareness, patient advocacy, Muscle Disease, myositis support

Awareness and Support for Rare Autoimmune Disease at Patient Conference in the Big Easy

The Myositis Association (TMA) hosts its 2016 Annual Patient Conference September 1-4 at the Hilton New Orleans Riverside. The conference aims to raise awareness of myositis, a rare autoimmune disease of the muscles, to educate patients about how best to manage symptoms and to provide patients and caregivers with a supportive community.

Medicine

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Myasthenia Gravis, thymectomy, Surgery, Neuro

Thymectomy Provides Broad Benefit to Myasthenia Gravis Patients Without a Chest Tumor, Study Finds

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Surgical removal of the thymus gland from patients with myasthenia gravis, a rare autoimmune disease that affects neuromuscular function, provides significant benefit in patients who do not have a chest tumor, a new study finds.

Medicine

Science

Channels:

Ticks, Venom, Autoimmune, Inflammatory, Akari Therapeutics, Gur Roshwalb, Ornithodoros moubata, Coversin, Complement, C5, paroxysmal nocturnal hemoglobinuria, PNH, atypical hemolytic uremic syndrome, aHUS, Guillain Barre Syndrome, GBS, Soliris, Eculizumab, Saliva

Expert: Scientists Turning to Animal Kingdom for Clues to New Drugs

Expert can speak on the use of animal toxins to develop a new generation of medicines. Gur Roshwalb, MD, Chief Executive Officer of Akari Therapeutics, is studying the use of Coversin—a molecule derived from the saliva of the Ornithodoros moubata tick—in potential treatments for conditions such as paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS) and Guillain Barré syndrome (GBS).

Medicine

Channels:

Autoimmune Disease, Autoimmunity, B Cell, Cell Development, Immunology, miR-17 , PTEN, miR-19, miR-17~92

TSRI Researchers Find ‘Lead Actors’ in Immune Cell Development

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A new study, led by scientists at The Scripps Research Institute, reveals a surprising twist in immune biology, suggesting that members of a cluster of microRNAs work together throughout the different stages of immune cell generation.

Medicine

Channels:

Autoimmunity, Vaccines, Immune System Decliine, Antibodies, Microrna, microRNA-155, T Follicular Helper Cells, lupus and pregnancy, Rheumatoid Arthritis, T Cell

Found: A Potential New Way to Sway the Immune System

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A new international collaboration involving scientists at The Scripps Research Institute opens a door to influencing the immune system, which would be useful to boost the effectiveness of vaccines or to counter autoimmune diseases such as lupus and rheumatoid arthritis.

Life

Education

Channels:

Aarda, Autoimmune Disease, Autoimmunity, Immunity, Joe Biden, Vitiligo, Psoriasis, NIH, Henry Waxman, Lupus, Vasculitis, Sjogren's Syndrome, Sarcoidosis

AARDA Salutes July #Autoimmune Heroes for Spearheading National Leadership, Collaboration on Autoimmune Disease Research

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American Autoimmune Related Diseases Association (AARDA) announced today its July Autoimmune Heroes.

Medicine

Channels:

Aarda, Dr. Noel Rose, Research, Autoimmune Disease, Immunity, Autoimmune Advocacy, t-cells, Science, car

New Research Studies Identify Potential Cause of and New Treatment for Autoimmune Diseases

The American Autoimmune Related Diseases Association, Inc. (AARDA) is spotlighting two new research studies originally reported in ScienceDaily.

Life

Education

Channels:

Aarda, Charity Navigator, Autoimmune Disease, Lupus, Vasculitis, Graves Disease, Immune System

AARDA Rated “4-Star” Nonprofit by Charity Navigator

Recognizing the American Autoimmune Related Diseases Association, Inc’s (AARDA) strong financial health and commitment to accountability and transparency, Charity Navigator has awarded the organization its highest, 4-star rating for the seventh time in the last eight years.

Medicine

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New Therapy Treats Autoimmune Disease Without Harming Normal Immunity

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In a study with potentially major implications for the future treatment of autoimmunity and related conditions, scientists have found a way to remove the subset of antibody-making cells that cause an autoimmune disease, without harming the rest of the immune system.

Medicine

Channels:

Autoimmune, Research, Lupus, Sjogren's Syndrome, Noel Rose

AARDA Salutes June #Autoimmune Hero for Collaborative Research

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As part of its ongoing 25th Anniversary celebration, American Autoimmune Related Diseases Association (AARDA) announced today its June Autoimmune Hero – Johns Hopkins University’s Autoimmune Disease Research Center (ADRC).

Medicine

Channels:

Autoimmune Disease, Autoimmune Disorders, Lupus, Sjogren's Syndrome, Sjogren syndrome , Interferon

Researchers Discover Potential Genetic Trigger of Autoimmune Disease

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Researchers at Hospital for Special Surgery (HSS) have uncovered a potential genetic trigger of systemic autoimmune disease.

Medicine

Channels:

Carlos Pardo-Villamizar, Steven Salzberg, Brain, Infection, DNA, Sequencing, Biopsy, Lesion, Genome, genetic, Disorder

Pilot Study Successfully Uses DNA Sequencing to Diagnose Brain Infections

In a proof-of-principle study, a team of physicians and bioinformatics experts at Johns Hopkins reports they were able to diagnose or rule out suspected brain infections using so called next-generation genetic sequencing of brain tissue samples.

Medicine

Channels:

Vasculitis, Autoimmune Disease, Autoimmune Advocacy, Autoimmune Disease And Disorder, Vasculitis Foundation

The Vasculitis Foundation 2016 Awareness Video

A short video produced by the Vasculitis Foundation to help raise awareness about vasculitis, a rare autoimmune disease. Also, the video promotes the non-profit, Vasculitis Foundation.

Medicine

Channels:

Rheumatoid Arthritis, Arthritis, Humira, Adalimumab, TNF, Inflammation

Researchers Uncover New Mode of Action for HUMIRA in Rheumatoid Arthritis Patients

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Researchers from University College London have discovered that the widely used antiinflammatory drug HUMIRA doesn’t just work by inhibiting its target protein, TNF, but by enhancing a particular function of TNF in rheumatoid arthritis patients. The study, “Anti-TNF drives regulatory T cell expansion by paradoxically promoting membrane TNF–TNF-RII binding in rheumatoid arthritis,” which will be published online June 6 in The Journal of Experimental Medicine, may help explain the divergent efficacies of different TNF-targeting drugs.







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