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Promising New NSAID-Derivative May Be Well-Tolerated by Chronic Pain Sufferers

Long-term use of naproxen (ALEVE), a type of nonsteroidal anti-inflammatory drug (NSAID), is often prescribed for chronic pain conditions such as osteoarthritis. However, because of NSAID-related gastrointestinal problems including stomach and intestinal inflammation and ulcers, many are unable to tolerate ongoing use. A new study, published in the American Journal of Physiology–Gastrointestinal and Liver Physiology, finds that a naproxen-derivative may provide both symptom relief and gastrointestinal protection. The research is highlighted as one of this month’s “best of the best” as part of the American Physiological Society’s APSselect program.

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Medical Marijuana, Autoimmune Disorders, Diabetes, SCOTUS experts - Top Stories 24 June 2015

Other topics include dietary guidelines, smart traffic lights, breast cancer, and biomarker tests for cancer treatment.

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Study Finds Most Women with Lupus Can Have Good Pregnancy Outcomes

One of the most prevalent and anxiety-provoking concerns among patients with lupus is whether it is safe to become pregnant. A study led by researchers at Hospital for Special Surgery finds that most women can expect a good pregnancy outcome if their lupus is inactive and they are free of risk factors.

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Pregnancy Safer for Women with Lupus than Previously Thought

New findings may help ease concerns for women with lupus who are interested in having a child. A new study concludes that most women with lupus whose disease is not very active will have a safe pregnancy. The results are to publish online June 22 in Annals of Internal Medicine.

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Cells Too Stiff to Scavenge Leads to Lupus, an Autoimmune Disease

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Macrophage cells require agility to scavenge and digest dead cells and prevent an immune response to self. In lupus, the macrophages lose that agility.

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Rare Autoimmune Disorder Found to Have a Common Form

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Scientists from the Weizmann Institute and the University of Bergen have found that a hereditary autoimmune disease (autoimmune polyendocrine syndrome type 1), thought to be very rare, may have a less severe form that affects at least one in 1,000 people. The results suggest that other autoimmune conditions may be tied to mutations in a single gene.

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Study Shows Acute Pulmonary Fibrosis May Respond to Autoimmune Disease Therapy

Patients with acute exacerbations of idiopathic pulmonary fibrosis responded well to therapies similar to those used to treat autoimmune diseases, suggesting that autoantibodies may play an important role in patients with acute exacerbations of IPF, a devastating lung disease.

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Trending Stories Report for 16 June 2015

Trending news releases with the most views in a single day. Topics include: An anonymous donor for cancer research, solar storms and incidences of rheumatoid arthritis, vulnerabilities in genome’s ‘Dimmer Switches’, new treatments for Alzheimer's, How people make decisions for or against flu vaccinations.

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Researchers Correlate Incidences of Rheumatoid Arthritis and Giant Cell Arteritis with Solar Cycles

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New release reports correlation between incidences of rheumatoid arthritis and giant cell arteritis with solar cycles.

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People with Multiple Sclerosis May Have Double the Risk of Dying Early

New research suggests people with multiple sclerosis (MS) may have double the risk of dying early compared to people without MS, with those younger than 59 at a three times higher risk. The study is published in the May 27, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology.