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Genetic Overlapping in Multiple Autoimmune Diseases May Suggest Common Therapies

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Scientists who analyzed the genes involved in 10 autoimmune diseases that begin in childhood have found 22 genome-wide signals shared by two or more diseases. These shared gene sites may reveal potential targets for treatment with existing drugs.

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Big Data and the Social Character of Genes

In a new study, researchers managed to narrow down 900 million possibilities requiring examination of the connection between genetic markers and genetic expression to just 340,000, in the process identifying “social” genes that play a cooperative role

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Molecular Study Points to Possible Therapy for Autoimmune Disease TTP

Molecular details of ADAMTS13 binding by autoantibodies reveal, for the first time, the mechanism of inhibition of ADAMTS13 by those autoantibodies and suggest an avenue for therapeutic intervention.

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Alefacept Preserves Beta Cell Function in Some New-Onset Type 1 Diabetes Patients Out to Two Years

Individuals with new-onset type 1 diabetes who took two courses of alefacept (Amevive®, Astellas Pharma Inc.) soon after diagnosis show preserved beta cell function after two years compared to those who received a placebo.

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Exercise for Arthritis, Summer Weight Loss, ACA and Lower Drug Costs, and More Top Stories 8 July 2015

Other topics include autism research, biofuel sources, nutrition supplements, and more...

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Actor Haley Ramm and Cast of ABC Family’s Chasing Life Take the #Pajama Challenge for #AARDA and #Autoimmune Awareness

Actress Haley Ramm and the cast of ABC Family's "Chasing Life" accept the pajama challenge for the Autoimmune Disease Association and autoimmune disease awareness.

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Promising New NSAID-Derivative May Be Well-Tolerated by Chronic Pain Sufferers

Long-term use of naproxen (ALEVE), a type of nonsteroidal anti-inflammatory drug (NSAID), is often prescribed for chronic pain conditions such as osteoarthritis. However, because of NSAID-related gastrointestinal problems including stomach and intestinal inflammation and ulcers, many are unable to tolerate ongoing use. A new study, published in the American Journal of Physiology–Gastrointestinal and Liver Physiology, finds that a naproxen-derivative may provide both symptom relief and gastrointestinal protection. The research is highlighted as one of this month’s “best of the best” as part of the American Physiological Society’s APSselect program.

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Medical Marijuana, Autoimmune Disorders, Diabetes, SCOTUS experts - Top Stories 24 June 2015

Other topics include dietary guidelines, smart traffic lights, breast cancer, and biomarker tests for cancer treatment.

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Study Finds Most Women with Lupus Can Have Good Pregnancy Outcomes

One of the most prevalent and anxiety-provoking concerns among patients with lupus is whether it is safe to become pregnant. A study led by researchers at Hospital for Special Surgery finds that most women can expect a good pregnancy outcome if their lupus is inactive and they are free of risk factors.

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Pregnancy Safer for Women with Lupus than Previously Thought

New findings may help ease concerns for women with lupus who are interested in having a child. A new study concludes that most women with lupus whose disease is not very active will have a safe pregnancy. The results are to publish online June 22 in Annals of Internal Medicine.

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Cells Too Stiff to Scavenge Leads to Lupus, an Autoimmune Disease

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Macrophage cells require agility to scavenge and digest dead cells and prevent an immune response to self. In lupus, the macrophages lose that agility.

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Rare Autoimmune Disorder Found to Have a Common Form

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Scientists from the Weizmann Institute and the University of Bergen have found that a hereditary autoimmune disease (autoimmune polyendocrine syndrome type 1), thought to be very rare, may have a less severe form that affects at least one in 1,000 people. The results suggest that other autoimmune conditions may be tied to mutations in a single gene.

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Study Shows Acute Pulmonary Fibrosis May Respond to Autoimmune Disease Therapy

Patients with acute exacerbations of idiopathic pulmonary fibrosis responded well to therapies similar to those used to treat autoimmune diseases, suggesting that autoantibodies may play an important role in patients with acute exacerbations of IPF, a devastating lung disease.

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Trending Stories Report for 16 June 2015

Trending news releases with the most views in a single day. Topics include: An anonymous donor for cancer research, solar storms and incidences of rheumatoid arthritis, vulnerabilities in genome’s ‘Dimmer Switches’, new treatments for Alzheimer's, How people make decisions for or against flu vaccinations.

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Researchers Correlate Incidences of Rheumatoid Arthritis and Giant Cell Arteritis with Solar Cycles

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New release reports correlation between incidences of rheumatoid arthritis and giant cell arteritis with solar cycles.

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People with Multiple Sclerosis May Have Double the Risk of Dying Early

New research suggests people with multiple sclerosis (MS) may have double the risk of dying early compared to people without MS, with those younger than 59 at a three times higher risk. The study is published in the May 27, 2015, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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Trending Stories Report for 27 May 2015

Trending news releases with the most views in a single day. Topics include: genetics, cancer, nanotech, elderly care, marketing research, energy, children's health, and immunology.

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New Research ‘Challenges the Assumption That Arthritis Patients Take Their Medication Regularly’

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New UK research has challenged the assumption that people with rheumatoid arthritis always take their medication as prescribed.

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Register to Attend the International Vasculitis Symposium

Experts from the Mayo Clinic, Cleveland Clinic, Stanford, PENN, UNC, and the NIH will offer education and networking opportunities for people, families, and friends living with vasculitis, a family of rare autoimmune diseases.

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La Jolla Institute Scientists Reveal Potential New Drug Target for the Treatment of Rheumatoid Arthritis

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Researchers at the La Jolla Institute for Allergy and Immunology, in collaboration with colleagues the University of California, San Diego, identified a novel drug target for the treatment of rheumatoid arthritis that focuses on the cells that are directly responsible for the cartilage damage in affected joints.