A study led by scientists at Cincinnati Children’s reveals one mechanism involved in regulating when nephron formation ends. If translated to clinical practice years from now, the result could be reduced need for kidney transplants and fewer deaths from kidney disease.
An analysis of lymph node dissection in non-metastatic renal cell carcinoma indicates the procedure is often performed for stage 1 disease and shows no overall survival benefit. Investigators from Rutgers Cancer Institute of New Jersey presented the work at the Annual Meeting of the American Urological Association.
• Among hospitalized adults, those who experienced acute kidney injury were 44% more likely to be hospitalized for heart failure in the year after discharge.
Children who underwent cardiac surgery were less likely to develop acute kidney injury if they had been treated with acetaminophen in the first 48 hours after their procedures, according to a Vanderbilt study just published in JAMA Pediatrics.
The annual meeting of the Society for Academic Emergency Medicine (SAEM). The SAEM 2018 meeting will bring together more than 3,000 physicians, researchers, residents and medical students from around the world.
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Pediatric researchers have found that children and adults treated with some oral antibiotics have a significantly higher risk of developing kidney stones. This is the first time that these medicines have been linked to this condition. The strongest risks appeared at younger ages and among patients most recently exposed to antibiotics.
• Use of oral antibiotics was linked with an increased risk of developing kidney stones. • Risk decreased over time but was still elevated several years after antibiotic use. • Risk was highest for young patients.
Since 1968, UAB Medicine has performed more than 14,000 life-saving organ transplants.
At 4 months old, Raegen was diagnosed with congenital nephrotic syndrome.Early on in Raegen Allard’s life, her mother, Francisca Allard, noticed something wasn’t quite right with her beautiful daughter. Raegen would seem upset after she ate and her stomach was enlarged. She also had a bruise around her belly button, which worried Allard further.
The urine of kidney disease patients contains a diverse mix of bacteria such as Staphylococcus and Streptococcus, a Loyola University Chicago study has found. The findings could lead to new approaches to treating lower urinary tract problems such as urinary urgency and incontinence.
Among individuals with chronic kidney disease, those who slept 7 hours/day had higher health-related quality of life than those who slept ≤5 hours/day or ≥9 hours/day.
The American Society of Nephrology (ASN) is pleased to announce the signing of a Memorandum of Understanding (MOU) with the US Department of Health and Human Services (HHS) to establish the Kidney Innovation Accelerator (KidneyX). KidneyX will spur the development and commercialization of innovative technologies and therapeutics in the prevention, diagnosis, and treatment of kidney diseases.
The NCCN Foundation® announces Chinese, Czech, German, Italian, and Spanish translations of patient-focused booklets designed to help people with cancer make shared decisions about their treatment.
Doctors may do more good for diabetes patients by getting their cholesterol and blood pressure under control than by intensifying their glucose control.
Mayo Clinic的研究显示，移植的肝脏改变了受体的血液细胞的状况，减少了器官排斥反应的可能性。 这些发现发表在Kidney International杂志上。
• Sixty-four percent of US patients undergoing hemodialysis in 2011 received opioids for pain, which is one of the most common reported symptoms in this patient population. • Opioid use was associated with higher risks of altered mental status, fall, and fracture in a dose-dependent manner, and these risks were present even when patients were not prescribed high opioid doses.
El estudio descubrió que cuando los pacientes se someten al trasplante doble, el hígado tiene un efecto protector sobre el riñón.
The U.S. Food and Drug Administration granted approval to the combination of two immunotherapy drugs, ipilimumab and nivolumab, for the treatment of metastatic kidney cancer.
A landmark 2016 Cleveland Clinic study of widely used pain-relieving drugs showed that celecoxib (Celebrex) was associated with comparable cardiovascular safety and better gastrointestinal and kidney safety when compared with either naproxen (Naprosyn) and ibuprofen (Motrin). A new substudy, published today in the Journal of the American College of Cardiology, analyzed outcomes in PRECISION based on the presence or absence of aspirin use with specific NSAIDs (nonsteroidal anti-inflammatory drugs).
For Medicare accountable care organizations (ACOs), primary care management of common chronic diseases is an important strategy for providing cost-effective care. But early data suggest that the proportion of visits for chronic conditions delivered by primary care providers (PCPs) varied between ACOs, reports a study in the May issue of Medical Care, published by Wolters Kluwer.
Experts in pediatric kidney disease have published a new staging system to help doctors better predict the length of time until a child with chronic kidney disease will need to undergo a kidney transplant or start receiving dialysis. Although this type of prognostic guide exists for adults, this is the first such tool specific to children.
PHILADELPHIA – Jeffrey S. Berns, MD, associate chief of the division of Renal-Electrolyte and Hypertension in the Perelman School of Medicine at the University of Pennsylvania, received the 2018 Donald W. Seldin Distinguished Award from the National Kidney Foundation (NKF), an award given to clinicians who display excellence in clinical nephrology.
New research shines a light on specific cell types that drive normal or diseased kidney function at the molecular level.
• The risk of death due to infectious causes after kidney transplantation in Finland has dropped by half since the 1990s. • Common bacterial infections remain the most frequent cause of infection-related deaths among transplant recipients.
Regional anesthesia was shown to be superior to local anesthesia in study of dialysis patients
Belly fat affects the odds of women surviving kidney cancer but not men, according to a new study by researchers at Washington University School of Medicine in St. Louis. The findings suggest that kidney cancer may develop and progress differently in women than men.
Preterm neonates who are exposed to caffeine within the first seven days after birth have reduced incidence and severity of acute kidney injuries than neonates who did not, according to findings from the Neonatal Kidney Collaborative’s Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates study, published in JAMA Pediatrics.
Krista Lentine, M.D., Ph.D., a professor of internal medicine at Saint Louis University, will receive a prestigious award from the National Kidney Foundation for her research and advocacy for living kidney donation.
Adults with diabetes are less likely to visit the dentist than people with prediabetes or without diabetes, finds a new study led by researchers at NYU Rory Meyers College of Nursing and East Carolina University’s Brody School of Medicine.
Click here for the latest research and features on Children's Health.
Advocates from the American Society of Nephrology (ASN) and the American Association of Kidney Patients (AAKP) are meeting with representatives, senators, and their respective staffs today to urge Congress to support KidneyX, a new public-private partnership to accelerate innovation in the prevention, diagnosis, and treatment of kidney diseases.
• Disadvantaged patients with kidney failure who received guidance from a trained navigator with a degree in social work were more likely to be eventually put on the transplant waiting list than control patients. • The difference in waitlisting among intervention vs. control patients became evident only after 500 days, however, at which point intervention patients were 3.3 times more likely to be waitlisted after 500 days.
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AACC is pleased to see an additional $2 million for lab test harmonization in the FY 2018 omnibus spending package. The association has worked to advance harmonization – or uniform test results -- for more than a decade, most recently leading efforts to raise awareness in Congress of the need for CDC funding for harmonization. AACC is gratified that its multiyear effort has resulted in a positive outcome. The new funding will enable CDC to broaden its harmonization initiative, which is vital to ensuring that patients receive accurate diagnoses and effective medical treatment.
• Kidney failure patients undergoing hemodialysis are vulnerable to infectious threats, many of which may be life-threatening and spread to others in dialysis facilities • New articles provide important information on infections and their prevention in patients undergoing hemodialysis and transmission in dialysis facilities.
Treating people with advanced metastatic kidney cancer using a combination of the immunotherapy drugs nivolumab (Opdivo®) and ipilimumab (Yervoy®) significantly increased overall survival versus treatment with sunitinib (Sutent®) alone, according to new findings from researchers at Memorial Sloan Kettering Cancer Center (MSK) that were reported today in the New England Journal of Medicine.
Highlight • In a study of Black Americans who participated in focus group sessions, certain participant factors—such as knowledge of kidney disease and spiritual and cultural influences—and logistical factors—such as convenience and awareness of scheduling—were identified as barriers that may prevent Black Americans from being screened for kidney disease.
Highlights • Between 2005 and 2015, the unadjusted rate of living kidney donation in the United States was 30.1 and 19.3 per million population in women and men, respectively. • After adjusting for differences in age, race, the incidence of kidney failure, and geographic factors, the incidence of donation was 44% higher in women. • Over time, the incidence of donation was stable in women but declined in men. The decline was most marked in men from lower income groups.
In a small study, doctors at Johns Hopkins have successfully transplanted 10 hepatitis C-infected kidneys into patients without hepatitis C and prevented the patients from becoming infected by hepatitis C. The success of these transplants could mean more organs being available for the nearly 100,000 people in the U.S. currently waiting for a kidney transplant.
In celebration of the World Kidney Day 2018’s theme of "Kidneys & Women’s Health: Include, Value, Empower," the American Society of Nephrology (ASN) is highlighting several articles in its journals, Clinical Journal of the American Society of Nephrology (CJASN) and Journal of the American Society of Nephrology (JASN), that are focused on women's kidney health.
Vanderbilt University Medical Center is encouraging its medical providers to stop using saline as intravenous fluid therapy for most patients, a change provoked by two companion landmark studies released today that are anticipated to improve survival and decrease kidney complications.
• An analysis of published studies indicates that children with chronic kidney disease may have lower intellectual functioning compared than children in the general population. • Compared with children with mild-to-moderate stage kidney disease and with kidney transplants, children on dialysis had the lowest IQ scores. • Deficits were evident for attention, memory, and executive function domains.
Researchers at Washington University School of Medicine in St. Louis have found that when mature cells transition to begin dividing again, they all seem to do it the same way, regardless of what organ those cells come from.
Lingering inflammation after heart attack can lead heart failure. It can also claim another victim — the kidneys. New research shows that a bioactive compound called resolvin D-1, injected as a therapeutic dose, is able to limit this collateral damage in the kidneys, as tested in an animal model.
• Three new research articles compare human and mouse kidney development to identify shared and novel features. • The studies provide new detailed molecular data to guide future research. • The studies revealed deep conservation of certain processes, but also significant differences in gene expression during kidney development, as well as in the timing, scale, organization, and molecular profile of key cell types and cell structures.
New guidelines developed collaboratively by the American Society of Clinical Oncology (ASCO) and the National Comprehensive Cancer Network® (NCCN®) offer clinicians much needed recommendations for assessment and management of side effects related to immune checkpoint inhibitors.
肾结石(Kidney stones)是十分痛苦的，而其治疗也往往需要多个令病人很不舒服的治疗程序。 越来越多的证据表明，肾结石的发病率在稳步上升，特别是在女性中。 使用罗切斯特流行病学项目(Rochester Epidemiology Project)的数据，Mayo Clinic的研究人员调查了结石患者的增加情况，以确定这是一个新的趋势或者仅仅是由于肾结石检测手段改善而造成的患者增加。 他们的发现发表在Mayo Clinic Proceedings上。
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