Feature Channels: Stem Cells

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Released: 26-May-2023 12:00 PM EDT
Modulation of stem cell fate in intestinal homeostasis, injury and repair
World Journal of Stem Cells

The mammalian intestinal epithelium constitutes the largest barrier against the external environment and makes flexible responses to various types of stimuli. Epithelial cells are fast-renewed to counteract constant damage and disrupted bar

Released: 26-May-2023 12:00 PM EDT
Stimulating factors for regulation of osteogenic and chondrogenic differentiation of mesenchymal stem cells
World Journal of Stem Cells

Mesenchymal stem cells (MSCs), distributed in many tissues in the human body, are multipotent cells capable of differentiating in specific directions. It is usually considered that the differentiation process of MSCs depends on specialized

Released: 26-May-2023 12:00 PM EDT
Molecular signaling in cancer stem cells of tongue squamous cell carcinoma: Therapeutic implications and challenges
World Journal of Stem Cells

Head and neck squamous cell carcinoma is the seventh most common cancer worldwide with high mortality rates. Amongst oral cavity cancers, tongue carcinoma is a very common and aggressive oral cavity carcinoma. Despite the implementation of

Released: 26-May-2023 12:00 PM EDT
Cell transplantation therapies for spinal cord injury focusing on bone marrow mesenchymal stem cells: Advances and challenges
World Journal of Stem Cells

Spinal cord injury (SCI) is a devastating condition with complex pathological mechanisms that lead to sensory, motor, and autonomic dysfunction below the site of injury. To date, no effective therapy is available for the treatment of SCI. R

Released: 26-May-2023 12:00 PM EDT
Stromal cell-derived factor-1α regulates chondrogenic differentiation via activation of the Wnt/β-catenin pathway in mesenchymal stem cells
World Journal of Stem Cells

BACKGROUNDMesenchymal stem cells (MSCs) have been applied to treat degenerative articular diseases, and stromal cell-derived factor-1α (SDF-1α) may enhance their therapeutic efficacy. However, the regulatory effects of SDF-1α on cartilag

Released: 26-May-2023 12:00 PM EDT
Human pluripotent stem cell-derived extracellular vesicles: From now to the future
World Journal of Stem Cells

Extracellular vesicles (EVs) are nanometric particles that enclose cell-derived bioactive molecules in a lipid bilayer and serve as intercellular communication tools. Accordingly, in various biological contexts, EVs are reported to engage i

Newswise: Groundbreaking Images of Root Chemicals Offer New Insights on Plant Growth
Released: 25-May-2023 7:05 PM EDT
Groundbreaking Images of Root Chemicals Offer New Insights on Plant Growth
University of California San Diego

Applying imaging technology to plant roots, researchers have developed a new understanding of chemicals that are responsible for plant growth. The chemical “roadmap” identifies where key molecules are distributed along corn roots and how their placement factors into the plant’s maturation.

Released: 25-May-2023 9:40 AM EDT
UTHealth Houston awarded nearly $13M in grants to study treatments for traumatic brain injury
University of Texas Health Science Center at Houston

Nearly $13 million in federal grant funds to study treatments for traumatic brain injury, which kills an average of 190 people and hospitalizes another 600 in the U.S. every day, has been awarded to UTHealth Houston by the Department of Defense’s Office of Congressionally Directed Medical Research Programs (CDMRP).

Newswise: SWI/SNF complexes “bookmark” cell identity during division
Released: 24-May-2023 11:15 AM EDT
SWI/SNF complexes “bookmark” cell identity during division
St. Jude Children's Research Hospital

Read about how Scientists at St. Jude determined how the SWI/SNF chromatin remodeling complex helps cancer cells remember how to be cancerous after division.

Newswise: UC San Diego First to Test Cancer Drugs in Space Using Private Astronaut Mission
Released: 22-May-2023 5:00 PM EDT
UC San Diego First to Test Cancer Drugs in Space Using Private Astronaut Mission
University of California San Diego

The latest space experiments from UC San Diego and Axiom Space will explore therapies for breast and colorectal cancer aboard the ISS, and monitor astronauts’ stem cell health over time.

Released: 16-May-2023 2:45 PM EDT
UC Irvine research team identifies glycosylation enzyme critical in brain formation
University of California, Irvine

The MGAT5 glycosylation enzyme plays a crucial role in brain development, according to a study by University of California, Irvine researchers, a discovery that may contribute to new therapeutic purposes for neural stem cells.

Released: 16-May-2023 2:00 PM EDT
May is Melanoma and Skin Cancer Awareness Month. Keep up with the latest news on skin in the Dermatology channel
Newswise

Skin cancer is the most prevalent form of cancer in the United States, with over 5 million cases diagnosed annually. The Centers for Disease Control and Prevention reports that melanoma alone accounts for more than 8,000 deaths each year. Thankfully, skin cancer is highly preventable, making it crucial to prioritize protection. Below are some of the latest headlines in the Dermatology channel.

Newswise: Engineers building tools to improve quality, production of disease-fighting cells
Released: 16-May-2023 12:05 PM EDT
Engineers building tools to improve quality, production of disease-fighting cells
Iowa State University

Iowa State University engineers are developing advanced tools for cell manufacturing that could improve the cost and availability of therapeutic cells capable of fighting diseases such as cancers, heart disease, lupus and other autoimmune diseases.

   
Newswise:Video Embedded nei-scientists-publish-recipe-for-making-blood-vessel-cells-from-patient-stem-cells
VIDEO
Released: 16-May-2023 9:30 AM EDT
NEI Scientists publish recipe for making blood vessel cells from patient stem cells
NIH, National Eye Institute (NEI)

Researchers at NIH’s National Eye Institute have published a detailed protocol for making three cell types that are key components to form blood vessels and capillaries.

Newswise: Research Identifies New Cause of Heart Failure Condition in Children
Released: 10-May-2023 10:05 AM EDT
Research Identifies New Cause of Heart Failure Condition in Children
University of Maryland School of Medicine

In an effort to determine the cause behind a rare condition that causes heart failure in children, University of Maryland School of Medicine researchers have identified new gene mutations responsible for the disorder in an infant patient. They were then able to learn how the mutation works and used a drug to reverse its effects in heart muscle cells derived from stem cells from the patient.

Newswise: Gamma delta T cells can fight aggressive breast cancer
Released: 4-May-2023 7:20 PM EDT
Gamma delta T cells can fight aggressive breast cancer
University of Freiburg

Researchers from the University of Frieburg discovered that coordinated differentiation and changes in the metabolism of breast cancer stem cells make them invisible for the immune system.

Newswise: UTSW researchers generate cattle blastoids in lab to aid farm animal reproduction
Released: 4-May-2023 3:45 PM EDT
UTSW researchers generate cattle blastoids in lab to aid farm animal reproduction
UT Southwestern Medical Center

UT Southwestern Medical Center stem cell and developmental biologists and colleagues have developed a method to produce bovine blastoids, a crucial step in replicating embryo formation in the lab that could lead to the development of new reproductive technologies for cattle breeding.

Newswise: April Research Highlights
Released: 28-Apr-2023 4:50 PM EDT
April Research Highlights
Cedars-Sinai

A roundup of the latest medical discoveries and faculty news at Cedars-Sinai for April 2023.

Newswise: Developing New Ways to Repair Tendons
Released: 27-Apr-2023 5:00 PM EDT
Developing New Ways to Repair Tendons
Cedars-Sinai

Cedars-Sinai investigators are working to develop a more effective treatment for one of the most common and hard-to-heal musculoskeletal injuries: torn tendons.



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