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Precision Medicine to Prevent Diabetes? Researchers Develop Personalized Way to Steer Prevention Efforts

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Researchers have just released a “precision medicine” approach to diabetes prevention that could keep more people from joining the ranks of the 29 million Americans with diabetes – using existing information like blood sugar levels and waist-to-hip ratios, and without needing new genetic tests.

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Development of Personalized Cellular Therapy for Brain Cancer

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Immune cells engineered to seek out and attack a type of deadly brain cancer were found to be both safe and effective at controlling tumor growth in mice that were treated with these modified cells. The results paved the way for a newly opened clinical trial for glioblastoma patients at Penn.

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Largest Ever Genome-Wide Study Strengthens Genetic Link to Obesity

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While diet and exercise are important, new findings sharpen the role genetics play in people’s tendency to gain weight and where the fat is stored. This work is the first step toward finding individual genes that play key roles in body shape and size.

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Does Getting “Expensive” Drug Affect How Much Patient Benefits?

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People’s perceptions of the cost of a drug may affect how much they benefit from the drug, even when they are receiving only a placebo, according to a new study of people with Parkinson’s disease published in the January 28, 2015 online issue of Neurology®, the medical journal of the American Academy of Neurology.

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Looking Ahead: Precision Immunology in Cancer

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With President Obama’s recent State of the Union speech addressing the launch of a national precision medicine initiative to further tackle cancer and other diseases, Howard L. Kaufman, MD, FACS, a leading immunotherapy expert from Rutgers Cancer Institute of New Jersey, weighs in on where we stand with precision immunology and personalized medicine and what needs to be accomplished.

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President Obama Calls for a New Initiative in “Precision Medicine”. Why Do We Need It?

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Precision Medicine: Mayo Clinic Expert Describes Next Steps to Help More Patients Benefit

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“Precision medicine” is becoming a national catchphrase after President Obama highlighted it in his State of the Union address. But what exactly is it? Richard Weinshilboum, M.D., acting director of the Mayo Clinic Center for Individualized Medicine, describes this new, rapidly advancing frontier in medicine and outlines 10 changes that would speed development and help more patients benefit from a personalized approach to health care:

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Scripps Florida Scientists Move Closer to a Personalized Treatment Solution for Intellectual Disability

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Scientists from the Florida campus of The Scripps Research Institute have produced an approach that completely protects animal models against a type of genetic disruption that causes intellectual disability, including serious memory impairments and altered anxiety levels.

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New Test Helps Guide Treatment for Bone Marrow Transplant Patients with Graft vs. Host Disease

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Innovative scoring system uses “Ann Arbor GVHD score” to better predict how patients will respond, minimize side effects

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Study Suggests Additional Applications for FL118 as Personalized Therapy for Cancer

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Scientists from Roswell Park Cancer Institute have reported new mechanisms of action of the novel anticancer agent FL118 and new potential therapeutic targets for the agent, a camptothecin analogue.