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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 17-Aug-2015 5:00 AM EDT

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New Technology Developed by Virginia Tech and the University of Iowa Helps Personalized Medicine by Enabling Epigenomic Analysis with a Mere 100 Cells

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A new technology, improving the efficiency of the studies in epigenomics, is the subject of a Nature Methods journal article by Chang Lu and Zhenning Cao of Virginia Tech and Kai Tan, Changya Chen and Bing He of the University of Iowa. The research was funded by the National Institutes of Health, following a seed grant from Virginia Tech’s Institute for Critical Technology and Applied Science.

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Patient Satisfaction Is Good Indicator of Success after Spinal Surgery

Patient satisfaction ratings after surgery for spinal degenerative disease—especially in terms of reduced pain and disability—are a good indicator of the procedure's effectiveness, reports a study in the August issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Wolters Kluwer.

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For Prostate Cancer Patients, Risk-Specific Therapies Now More the Norm

After decades of overtreatment for low-risk prostate cancer and inadequate management of its more aggressive forms, patients are now more likely to receive medical care matched to level of risk, according to a study by researchers at UC San Francisco.

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Supercharging Stem Cells to Create New Therapies

Researchers at the University of Adelaide have discovered a new method for culturing stem cells which sees the highly therapeutic cells grow faster and stronger.

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Genetic Variation Determines Protein’s Response to Anti-Diabetic Drug

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In the first study of its kind, researchers have shown how an anti-diabetic drug can have variable effects depending on small natural differences in DNA sequence between individuals. They aim to apply this knowledge to develop personalized approaches to treating diabetes and other metabolic disorders.

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UNC Lineberger Discovery Could Lead to Personalized Colon Cancer Treatment Approach

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In a study published in Nature Medicine, UNC Lineberger Comprehensive Cancer Center researchers report their findings of just how a certain tumor-suppressing protein helps prevent colon cancer. With this discovery, researchers believe they’ve found a possible drug target for colon cancer patients who lack the tumor suppressor.

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New Biomarkers Might Help Personalize Metastatic Colorectal Cancer Treatment

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Metastatic colorectal cancer patients tend to live longer when they respond to the first line of chemotherapy their doctors recommend. To better predict how patients will respond to chemotherapy drugs before they begin treatment, researchers at University of California, San Diego School of Medicine conducted a proof-of-principle study with a small group of metastatic colorectal cancer patients. The results revealed two genes that could help physicians make more informed treatment decisions for patients with this disease.

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Mount Sinai Scientists Shed Light on the Motivations of Healthy People Seeking Personal Genome Sequencing

Research will help inform the transition of healthcare to “precision medicine”, where individuals and physicians will routinely obtain and apply genomic information

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UAB Study Says Race Influences Warfarin Dose – an Advance for Personalized Medicine

A new report from UAB demonstrates that clinical and genetic factors affecting dose requirements for warfarin vary by race. The study, published online today in Blood, proposes race-specific equations to help clinicians better calculate warfarin dosage.