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Tissue Collection Aids Search for Neurologic and Neuromuscular Disease Causes and Cures

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Like other major research centers studying genetic causes of uncommon and poorly understood nervous system disorders, Cedars-Sinai maintains a growing collection of DNA and tissue samples donated by patients. What sets Cedars-Sinai’s Repository of Neurologic and Neuromuscular Disorders apart is its special emphasis on tissue collection – part of its focus on creating future individualized treatments for patients.

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Telemedicine Catches Blinding Disease in Premature Babies

Telemedicine is an effective strategy to screen for the potentially blinding disease known as retinopathy of prematurity (ROP), according to a study funded by the National Eye Institute (NEI). The investigators say that the approach, if adopted broadly, could help ease the strain on hospitals with limited access to ophthalmologists and lead to better care for infants in underserved areas of the country. NEI is a part of the National Institutes of Health.

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Mayo Clinic Recommends New Routine Testing for some Non-Hodgkin Lymphomas

A Mayo Clinic-led group of researchers has discovered three subgroups of a single type of non-Hodgkin lymphoma that have markedly different survival rates. These subgroups could not be differentiated by routine pathology but only with the aid of novel genetic tests, which the research team recommends giving to all patients with ALK-negative anaplastic large-cell lymphoma (ALCL). Findings are published in the journal Blood.

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Aging Accelerates Genomic Changes, Signaling Challenges for Personalized Medicine

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Virginia Bioinformatics Institute researchers at Virginia Tech have discovered aging can occur at different rates within an individual's genome, with some portions aging 100 times faster than others. It makes personalized medicine even more challenging.

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Genetics Provide Blueprint for New Heart Disease Therapies, Writes Penn Medicine Researcher

Advances in the understanding of the genetics of coronary artery disease, or CAD, will revitalize the field and lead to more therapeutic targets for new medicines to combat this common disease, suggests a genetics expert from the Perelman School of Medicine at the University of Pennsylvania in a Perspective article in the new issue of Science Translational Medicine.

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Will I Have Alzheimer’s? Personalized Dementia Risk Assessment Now Available at UAB

UAB is launching a new clinical effort — the first of its type in the US — to prepare a personalized dementia risk assessment for people concerned about their risk for developing memory problems as they age.

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New Test Measuring Cell Bioenergetic Health Could Become Key Tool in Personalized Medicine

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Researchers at the UAB School of Medicine have created an experimental blood test that, for the first time, determines a Bioenergetic Health Index, by gauging the performance of mitochondria, the cell’s energy powerhouses.

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Mice With MS-Like Condition Walk Again After Human Stem Cell Treatment

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Mice severely disabled by a condition similar to multiple sclerosis (MS) were able to walk less than two weeks following treatment with human neural stem cells. The finding, which uncovers potential new avenues for treating MS, will be published online on May 15, 2014, in the journal Stem Cell Reports.

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Genealogy and Biogeography Meet Personalized Medicine

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Biogeographical data is useful in screening for disease risk and drug sensitivity associated with certain ethnic groups. A team of researchers, including an investigator from Children’s Hospital Los Angeles, has developed a tool to accurately identify the biogeography of worldwide individuals.

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Cartilage, Made to Order

Scientists have created the first example of living human cartilage grown on a laboratory chip. The researchers ultimately aim to use their innovative 3-D printing approach to create replacement cartilage for patients with osteoarthritis or soldiers with battlefield injuries.

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