Cataracts surgery is recognized as a medical marvel, but even years after the procedure, some patients may experience "secondary cataracts." Melinda Duncan and her UD team have focused on scare tissue that forms after surgery to address the problem.
Zebrafish eye injected with retinoblastoma tumor cells (green) form a mass in areas close to the injection site. A few of these tumor cells move outside the eye. Credit: Johns Hopkins Medicine By comparing genetic sequences in the eye tumors of children whose cancers spread with tumors that didn’t spread, Johns Hopkins Medicine researchers report new evidence that a domino effect in cells is responsible for the cancer spreading. Their experiments suggest that blocking part of the chain of events — which they successfully accomplished in zebra fish and human cells — stops the growth and spread of the eye tumor cells.
Scientists at Johns Hopkins Medicine say they have identified what may be an ancient light-sensing mechanism in modern mouse retinal cells.
Shortly after birth when the world is a blur, babies may be learning to identify patterns. According to a new study funded by the National Eye Institute (NEI), the initial phase of blurry vision may be fundamental to the development of normal visual processing.
A new era in the management of glaucoma is ushered in by a landmark study published in the Journal of Glaucoma, Official Journal of the World Glaucoma Association. Patients with primary open angle glaucoma (POAG) showed significant improvements of both ocular and general health after participating in a program of mindful meditation focused on breathing compared to the control group that did not partake.
The grants are designed to foster cross-disciplinary cooperation among leading basic, translational and clinical neuroscientists in an effort to propel discoveries from laboratory to clinic.
Researchers from the University of California, Irvine School of Medicine, have discovered that neurons located in the vision centers of the brains of blind rats functioned normally following fetal retina cell transplants, indicating the successful restoration of vision. The research was published today in JNeurosci, the Journal of Neuroscience.
Rutgers researchers discover new technique to improve vestibular function, which assists with balance
Dr. Okihide Hikosaka, senior investigator at the National Eye Institute (NEI) Laboratory of Sensorimotor Research, is a recipient of the 2018 Gruber Prize in Neuroscience.
Fourth annual Forum will be held Feb. 28-March 2 in Dallas, Texas.
A monthly roundup of research briefs showcasing recent scientific advances led by Beth Israel Deaconess Medical Center faculty.
An Oct. 31 event at Children’s Hospital of Philadelphia highlights the Philadelphia's role in manufacturing 21st century products: tools for precision medicine. The hospital's new Clinical Manufacturing Facility will produce clinical-grade vectors to deliver cellular and gene therapy for difficult-to-treat diseases.
A new study led by researchers at Massachusetts Eye and Ear found that good performance on a piloting task was associated with lower vestibular thresholds, which represent stronger ability to sense and perceive information about motion, balance and spatial orientation. Published online today in the Journal of Neurophysiology, the findings suggest that astronauts or pilots with higher vestibular thresholds are more likely to become disoriented during flight, especially in situations when gravity is less than that on Earth – such as on the Moon.
A team of ophthalmologists went looking for scientific evidence in support of commercially available “cell therapy” for eye diseases. Not only did they find virtually none; they instead discovered a growing number of patients are being irreparably harmed by unapproved cell therapies.
A study examining the diagnoses generated by WebMD Symptom Checker showed the online tool was correct only 26 percent of the time. And the recommendation for the top diagnosis was often inappropriate, at times recommending self-care at home instead of going to the emergency room.
Rutgers Doctor Uses Flying Hospital To Help Patients Around The World
Results from two studies show that a new, non-invasive imaging device can see signs of Alzheimer’s disease in a matter of seconds. The researchers show that the small blood vessels in the retina at the back of the eye are altered in patients with Alzheimer’s.
The American Academy of Ophthalmology today announced a $2 million gift from the Knights Templar Eye Foundation (KTEF) to establish a permanent research fund to advance the practice of pediatric ophthalmology.
The American Academy of Ophthalmology is honoring exceptional ophthalmologists whose contributions have improved patient care and advanced the profession at AAO 2018, the Academy’s 122nd annual meeting in Chicago.
The American Academy of Ophthalmology today announced a project to construct the world’s first public museum dedicated to vision and eye health. The new museum will be located in San Francisco.
A new study shows that an implantable delivery system for a widely used medication to treat a blinding eye disease has enabled some patients to go 15 months in between treatments. This represents a vast improvement over the typical regimen of nearly monthly eye injections.
The art and science of eye care on display during the 122nd annual meeting of the American Academy of Ophthalmology
Patients can now receive eye surgery and other ophthalmology care close to home at the University of Michigan Kellogg Eye Center’s new state-of-the-art clinic in Brighton.
Scientists at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research and the Stein Eye Institute have been awarded a $5.1 million grant from the California Institute for Regenerative Medicine to advance the development of a novel therapy for blinding retinal conditions.
Researchers at the University of Minnesota, with support from NIBIB, used a 3-D bioprinting technique to print photordetectors onto a curved surface. Through the combination of design innovation and the use of materials—including synthetic conducting polymers, functional electronics, and biological tissue—the team is creating prototypes of multiple replacement body parts, including skin, ears, spinal cord, and now a bionic eye.
Biologists at Johns Hopkins University grew human retinas from scratch to determine how cells that allow people to see in color are made.
Two summers ago, biomedical engineering students at Rutgers University–New Brunswick immersed themselves at Matheny in Peapack, New Jersey, a nonprofit organization that is home to scores of children and adults with cerebral palsy, spina bifida and other developmental disabilities. The students’ goal: find ways to improve their independence and quality of life. After talking with staffers and students at Matheny, the Rutgers students designed prototypes that were demonstrated there last spring. The reaction was very positive.
Researchers at the University of Illinois at Chicago have received a four-year, $5.25 million grant from the U.S. Department of Defense to lead a multi-site clinical trial to test the efficacy of a stem cell-based treatment for eye injuries.The treatment uses mesenchymal stem cells — cells that can differentiate into fat, bone or cartilage, but which also produce an abundance of anti-inflammatory factors that have been shown to speed healing and reduce scaring in experimental models of eye injury.
Columbia Engineers have created the first flat lens capable of correctly focusing a large range of colors of any polarization to the same focal spot without the need for any additional elements. Only a micron thick, their revolutionary "flat" lens is much thinner than a sheet of paper and offers performance comparable to top-of-the-line compound lens systems. UPenn nanophotonics expert Nader Engheta, who was not involved with this study, notes: "This…is an exciting development in the field of flat optics.”
Study serves as a warning about excessive use or over-dosage
For those in the habit of getting their neck adjusted, there's an important case to know about: High velocity neck manipulation have been shown to cause stress on the eye and vision loss.
Research to Prevent Blindness (RPB) and Lions Club International Foundation (LCIF) announced today that they will continue their partnership in the RPB/LCIF Low Vision Research Award.
Evidence is mounting that a poor diet plays an important role in the development of age-related macular degeneration (AMD), a leading cause of blindness in the United States.
Delivery of corticosteroids directly into the eye is more effective than injections adjacent to the eye, according to results from a comparative clinical trial of macular edema in patients with noninfectious uveitis.
Results may lead to better management of complex eye condition
During aging, loss of vision and cognition often coincide. In a new study, researchers funded by the National Eye Institute (NEI) and National Institute on Aging (NIA) have found that vision loss precedes loss of mental capacity. The findings suggest that maintaining eye health could help protect cognition in older adults.
glaucoma does affect reading. Why? First, while glaucoma does affect peripheral vision, it also affects central vision. Glaucoma patients with moderate or severe disease often describe looking through a fog which extends into their central vision.
Glaucoma is a disease where the optic nerve gets damaged and the main risk factor is elevated eye pressure (also called intraocular pressure, IOP). The only treatment is to lower the IOP.
Exposure to artificial Earth-like gravity in space may be the answer to vision problems faced by astronauts.
Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) have found that the anti-malaria drug amodiaquine inhibits the apelin receptor protein, which helps drive the vascularization behind diabetic retinopathy, wet age-related macular degeneration (AMD) and other conditions. Because the drug has been approved to treat malaria for decades, it could move relatively quickly through the pipeline to help patients. The study was published in the journal PLOS ONE.
Researchers at The University of Texas MD Anderson Cancer Center have shown how BRCA-associated protein 1 (BAP1) serves as a tumor suppressor gene in kidney, eye, bile duct, mesothelioma and other cancers by regulating a form of cell death called ferroptosis, opening up a potential new area of therapy research. Findings from the study, led by Boyi Gan, Ph.D., associate professor, Department of Experimental Radiation Oncology, were published in the Sept. 10 online issue of Nature Cell Biology.
Low vision devices such as magnifiers, talking materials and telescopic glasses are game-changers for the visually impaired. But a University of Michigan Kellogg Eye Center study shows some older adults who have trouble seeing are missing out on the devices that can help them read, drive and socialize.
A natural plant compound exploits a newly identified Achilles’ heel in a cancer of the eye, uveal melanoma. In human cancer cells growing in the lab, the compound shuts down the overactive signaling that drives uveal melanoma cell growth, according to researchers at Washington University School of Medicine in St. Louis.
A new poll suggests that primary care providers could play an important role in promoting vision care for adults age 50 and older, especially for those most in need of eye exams, and those most sensitive to the cost.
Three Penn Medicine ophthalmology innovators received the 2018 António Champalimaud Vision Award for their revolutionary work leading to the first successful gene therapy to cure an inherited cause of childhood blindness.
Magdeburg, Germany, September 4, 2018 - About one third of patients who have suffered a stroke end up with low vision, losing up to half of their visual field. This partial blindness was long considered irreversible, but recent studies have shown that vision training after optic nerve and brain damage can help restore or improve vision.
A team of scientists has uncovered a neurological synergy that occurs in visual adaptation, a phenomenon in which perception is altered by prolonged exposure to a stimulus.
Jayakrishna Ambati, MD, has been selected as the 2018 RPB David F. Weeks Award for Outstanding AMD Research (Weeks Award).
A team of researchers at the University of Minnesota have, for the first time, fully 3D printed an array of light receptors on a hemispherical surface. This discovery marks a significant step toward creating a “bionic eye” that could someday help blind people see or sighted people see better.
UAB eye physicians say it is never too early to start caring for your child’s ocular health.
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