Feature Channels

Blood Disorders

Filters:

  • (Press "esc" to clear)

Medicine

Channels:

Drug for Rare Blood Disorder Developed at Penn Receives Orphan Drug Status from EU

A Penn Medicine-developed drug has received orphan status in Europe this week for the treatment of paroxysmal nocturnal hemoglobinuria, a rare, life-threatening disease that causes anemia due to destruction of red blood cells and thrombosis.

View | Comment

Medicine

Channels:

Keywords:

Regular Blood Transfusions Can Stave Off Repeat Strokes in Children With Sickle Cell Disease

Monthly blood transfusions can substantially reduce the risk of recurrent strokes in children with sickle cell disease (SCD) who have already suffered a silent stroke, according to the results of an international study by investigators at the Johns Hopkins Children’s Center, Vanderbilt University and 27 other medical institutions.

View | Comment

Medicine

Channels:

Keywords:

Regular Blood Transfusions Can Reduce Repeat Strokes in Children with Sickle Cell Disease

Vanderbilt-led research, as part of an international, multicenter trial, found regular blood transfusion therapy significantly reduces the recurrence of silent strokes and strokes in children with sickle cell anemia who have had pre-existing silent strokes, according to study results released today in the New England Journal of Medicine (NEJM).

View | Comment

Medicine

Channels:

Keywords:

Monthly Transfusions Reduce Strokes in Children with Sickle Cell Anemia

silentstrokes3.jpg

Monthly blood transfusions reduce the risk of stroke in young patients with sickle cell anemia, scientists report Aug. 20 in The New England Journal of Medicine.

View | Comment

Medicine

Channels:

Keywords:

Forcing Chromosomes into Loops May Switch Off Sickle Cell Disease

Scientists have altered key biological events in red blood cells, causing the cells to produce a form of hemoglobin normally absent after the newborn period. This approach may lead to a novel treatment for sickle cell disease.

View | Comment

Medicine

Channels:

Keywords:

Drug Target Identified for Common Childhood Blood Cancer

In what is believed to be the largest genetic analysis of what triggers and propels progression of tumor growth in a common childhood blood cancer, researchers at NYU Langone Medical Center report that they have identified a possible new drug target for treating the disease.

View | Comment

Medicine

Channels:

Scientists Discover Genetic Switch That Can Prevent Peripheral Vascular Disease in Mice

VihangNarkarFINAL.jpg

Millions of people in the United States have a circulatory problem of the legs called peripheral vascular disease. It can be painful and may even require surgery in serious cases. This disease can lead to severe skeletal muscle wasting and, in turn, limb amputation.

View | Comment

Medicine

Channels:

Keywords:

Liver Transplant Patients Who Receive Organs from Living Donors More Likely to Survive than Those Who Receive Organs from Deceased Donors

Goldberg-David.JPG

Research derived from early national experience of liver transplantation has shown that deceased donor liver transplants offered recipients better survival rates than living donor liver transplants, making them the preferred method of transplantation for most physicians. Now, the first data-driven study in over a decade disputes this notion. Penn Medicine researchers found that living donor transplant outcomes are superior to those found with deceased donors with appropriate donor selection and when surgeries are performed at an experienced center. The research is published this week in the journal Hepatology.

View | Comment

Medicine

Channels:

Keywords:

SLU Scientists Hit ‘Delete’: Removing Disordered Regions of Shape-Shifting Protein Explains How Blood Clots

DiCera_kringle_450.jpg

Researchers used x-ray crystallography to publish the first image of prothrombin. The protein’s flexible structure is key to the development of blood-clotting.

View | Comment

Medicine

Channels:

Keywords:

Wisconsin Scientists Find Genetic Recipe to Turn Stem Cells to Blood

BloodCellImage.jpg

The ability to reliably and safely make in the laboratory all of the different types of cells in human blood is one key step closer to reality.

View | Comment