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Liver Transplant Patients Who Receive Organs from Living Donors More Likely to Survive than Those Who Receive Organs from Deceased Donors

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Research derived from early national experience of liver transplantation has shown that deceased donor liver transplants offered recipients better survival rates than living donor liver transplants, making them the preferred method of transplantation for most physicians. Now, the first data-driven study in over a decade disputes this notion. Penn Medicine researchers found that living donor transplant outcomes are superior to those found with deceased donors with appropriate donor selection and when surgeries are performed at an experienced center. The research is published this week in the journal Hepatology.

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SLU Scientists Hit ‘Delete’: Removing Disordered Regions of Shape-Shifting Protein Explains How Blood Clots

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Researchers used x-ray crystallography to publish the first image of prothrombin. The protein’s flexible structure is key to the development of blood-clotting.

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Wisconsin Scientists Find Genetic Recipe to Turn Stem Cells to Blood

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The ability to reliably and safely make in the laboratory all of the different types of cells in human blood is one key step closer to reality.

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Biochemical Cascade Causes Bone Marrow Inflammation, Leading to Serious Blood Disorders

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Like a line of falling dominos, a cascade of molecular events in the bone marrow produces high levels of inflammation that disrupt normal blood formation and lead to potentially deadly disorders including leukemia, an Indiana University-led research team has reported.

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Researchers Find New Way to Prevent Dangerous Blood Clots

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For the first time, scientists at the UNC School of Medicine have shown that eliminating the enzyme factor XIII reduces the number of red blood cells trapped in a clot, resulting in a 50 percent reduction in the size of the clot.

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Antibiotic Therapy Reduces Mortality by 68 Percent in Hemodialysis Patients

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An antibiotic therapy known to reduce catheter-related bloodstream infections in hemodialysis patients has been shown for the first time to reduce mortality, according to a Henry Ford Health System study.

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Bone Marrow Transplantation Shows Potential for Treating Adults with Sickle Cell Disease

Use of a lower intensity bone marrow transplantation method showed promising results among 30 patients (16-65 years of age) with severe sickle cell disease, according to a study in the July 2 issue of JAMA.

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Efforts to Cut Unnecessary Blood Testing Bring Major Decreases in Health Care Spending

Researchers at Johns Hopkins Bayview Medical Center used two relatively simple tactics to significantly reduce the number of unnecessary blood tests to assess symptoms of heart attack and chest pain and to achieve a large decrease in patient charges.

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Engineered Red Blood Cells Could Carry Precious Therapeutic Cargo

Whitehead Institute scientists have genetically and enzymatically modified red blood cells to carry a range of valuable payloads—from drugs, to vaccines, to imaging agents—for delivery to specific sites throughout the body.

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Scripps Research Institute Scientists Find Potential New Use for Cancer Drug in Gene Therapy for Blood Disorders

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Scientists working to make gene therapy a reality have solved a major hurdle: how to bypass a blood stem cell’s natural defenses and efficiently insert disease-fighting genes into the cell’s genome.

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