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Embargo will expire:
27-Apr-2018 9:00 AM EDT
Released to reporters:
23-Apr-2018 9:05 AM EDT

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Article ID: 693265

CHIPing Away at Cancer Tumors Through Genomic Analysis

Rutgers Cancer Institute of New Jersey

Investigators at Rutgers Cancer Institute have discovered that some mutations detected in comprehensive, clinical genome sequencing of patients with solid tumors do not originate from cancer cells, but arise from mutated hematopoietic cells that infiltrate the tumor microenvironment. The findings, they say, have direct implications for cancer patients, specifically in accurately interpreting their molecular testing results and ensuring that treatment is focused on somatic tumor-specific mutations.

Released:
23-Apr-2018 8:05 AM EDT
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Article ID: 670310

PTSD Therapies, Safety Measures in Low-Income Countries, Race and Opioids, and More in the Public Health News Source

Newswise

The latest research, experts and features in Public Health in the Public Health News Source

Released:
22-Apr-2018 5:05 PM EDT
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Article ID: 693121

Chip-Based Blood Test for Multiple Myeloma Could Help Make Bone Biopsies a Relic of the Past

University of Kansas Cancer Center

A new University of Kansas research effort featured in the current edition of Integrative Biology has resulted in a low-cost, reliable blood test that uses a small plastic chip about the size of a credit card that can deliver the same diagnostic information as a bone biopsy — but using a simple blood draw instead.

Released:
19-Apr-2018 11:05 AM EDT
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  • Embargo expired:
    18-Apr-2018 5:00 PM EDT

Article ID: 693120

Pioneering Gene Therapy by UCSF Benioff Children’s Hospital Oakland Researchers Demonstrates Therapy Can Eliminate Life-Long Need for Transfusions in Patients with Incurable Blood Disorder

UCSF Benioff Children's Hospital Oakland

Interim results of clinical trials by investigators at UCSF Benioff Children’s Hospital Oakland and Ann and Robert H. Lurie Children’s Hospital of Chicago reveal that a majority of the 22 patients in two Phase 1/2 studies followed for two years or longer remained free from transfusions. The results of the trials “Gene Therapy in Patients with Transfusion-Dependentβ-Thalassemia,” are published today in the New England Journal of Medicine (NEJM). The results are from two separate, two-year clinical studies using LentiGlobin® gene therapy to stop or reduce chronic blood transfusions in patients with transfusion-dependent β-thalassemia (TDT).

Released:
18-Apr-2018 6:05 PM EDT
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Article ID: 692943

Is Caregiver Education About Sickle Cell Trait Effective?

Nationwide Children's Hospital

Despite universal newborn screening that detects the presence of sickle cell trait (SCT), only 16 percent of Americans with SCT know their status. To address this issue, in Ohio, in-person education is offered to caregivers of referred infants with SCT.

Released:
17-Apr-2018 10:30 AM EDT
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Article ID: 692953

Johns Hopkins Students Devise One-Size-Fits-All Blood-Clotting Tool

Johns Hopkins University

Students develop a blood-clotting “super gel” that can be injected through a catheter but is hyper-absorbent enough to then swell with blood, blocking further bleeding.

Released:
17-Apr-2018 10:05 AM EDT
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Article ID: 692689

Atlantic HPV Center to Help Lead Multicenter Trial of Novel Combination Treatment for Advanced Head and Neck Cancer Caused by HPV

Atlantic Health System

Atlantic Health System’s new Atlantic HPV Center is one of a small number of research centers in the nation to begin a study to determine whether an innovative combination of immuno-oncology treatments is safe, shows preliminary efficacy and provokes an anticancer immune system response in patients with recurrent or metastatic human papilloma virus (HPV) associated head and neck squamous cancer.

Released:
12-Apr-2018 11:05 AM EDT
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  • Embargo expired:
    11-Apr-2018 2:00 PM EDT

Article ID: 692506

Novel Drug Shows Promise Against Acute Myeloid Leukemia

Albert Einstein College of Medicine

In a study published online today in Science Translational Medicine, Albert Einstein College of Medicine researchers report that an experimental peptide (small protein) drug shows promise against the often-lethal cancer acute myeloid leukemia (AML) and describe how the drug works at the molecular level. The findings have led to a Phase I/II clinical trial for patients with advanced AML and advanced myelodysplastic syndrome (MDS), now underway at Montefiore Health System.

Released:
10-Apr-2018 10:00 AM EDT
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Article ID: 692592

How Do Children Develop Immunity to Malaria as They Become Older?

Case Western Reserve University

Across the world, over 200 million cases of malaria and nearly 500,000 deaths from the disease occur annually—more than 90 percent of which happen in Africa. Children in Africa can be diagnosed with malaria two or three times a year, a rate that decreases as they become older and develop immunity. But the way children generate and maintain this immunity remains a mystery. Katherine Dobbs, MD, a tropical infectious diseases and malaria researcher, is conducting research in Kenya to find answers by studying white blood cells important to innate immunity, the body’s “first response” to infection.

Released:
11-Apr-2018 10:05 AM EDT
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