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Medicine

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iron metabolism, Ferritin, Oxidative Stress, Israel, Alzheimber's Disease, Parkinson's Disease, Neurologic Disorders

The Human Body's Golden Gate to Iron Traffic

New findings could change how iron metabolism in the human body is understood, and open new horizons for research and therapeutics for inflammatory diseases and neurodegenerative diseases, such as Alzheimer’s and Parkinson's disease.

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Cancer, Dr. Robert Kyle, Dr. S. Vincent Rajkumar, Mayo Clinic, Medical Research, MGUS, Minnesota News Releases, Monoclonal Gammopathy of Undetermined Significance, Multiple Myeloma, New England Journal Of Medicine, news releases

Patients with Blood Cancer Precursor at Risk of Developing Cancer Even After 30 Years

Patients with monoclonal gammopathy of undetermined significance are at risk of progressing to multiple myeloma or a related cancer ─ even after 30 years of stability. These are the findings of a study by Mayo Clinic researchers published in the Wednesday, Jan. 17, issue of the New England Journal of Medicine.

Medicine

Science

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sickle cell disease organ failure, Sickle Cell Anemia Research, Supercomputing, Modeling & Simulation, High Performace Computing, Medical Research

A Shortcut to Modeling Sickle Cell Disease

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Using Oak Ridge National Laboratory's Titan supercomputer, a team led by Brown University’s George Karniadakis devised a multiscale model of sickle cell disease that captures what happens inside a red blood cell affected by the disease.

Medicine

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Stroke, Ischemic Stroke, tPA, Tpa Treatment, Door to Needle Time, Pharmacists, pharmacists and stroke, RTPA, Tissue Plasminogen Activator, recombinant tissue plasminogen activator

Having a Pharmacist at Stroke Patient's Bedside Speeds Administration of Critical Drug

In treating stroke patients, every minute counts. A drug called rtPA sometimes can stop a stroke in its tracks. Now a Loyola Medicine study has found that having a pharmacist at the patient's bedside can reduce the time it takes to administer rtPA by a median of 23.5 minutes.

Medicine

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High Cholesterol, cholesterol management, Penn Medicine, perelman school of medicine , Health Insurance, Prescription Drug Benefit, Cardiology, Cardiovascular Medicine, PCSK9 Inhibitors, Cardiovascular Quality

Insurance Company Requirements Place Heavy Administrative Burden on Physicians Seeking to Prescribe New Cholesterol-Lowering Drugs

A rare glimpse into the prior authorization requirements implemented by public and private insurance providers across the country has found substantial administrative burden for a new class of medications for patients with high cholesterol that places them at high risk for heart attack or stroke. So-called proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are self-injected medications approved for individuals with a genetic condition called familial hypercholesterolemia (FH) and those with atherosclerotic cardiovascular disease (ASCVD) who have high cholesterol despite receiving traditional statin medications and other treatments. Results of the study are published in Circulation: Cardiovascular Quality and Outcomes.

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CAP Guideline Details HPV Testing in Head, Neck Cancers

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Certain head and neck cancers that are positive for high-risk types of human papillomavirus (HPV) have a better prognosis and may need less aggressive treatment.

Medicine

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Mitochondrial Disease, Vitamins And Supplements, nutritional interventions , mitochondrial medicine, Dietary Supplements, preclinical testing, Precision Medicine

Can Vitamins and Dietary Supplements Benefit Patients with Mitochondrial Disease?

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Defects in mitochondria, the tiny structures that power our cells by functioning as biological batteries, cause an array of complex, often life-threatening disorders that can affect any and all organs and systems. In the absence of validated, effective drug treatments, patients with mitochondrial disease often take a variety of vitamins and supplements, substances that are largely unstandardized, unregulated, and unproven. A group of medical experts recommend performing systematic scientific studies to test precise nutritional interventions for patients.

Medicine

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Beta Blockers, Melanoma, Cancer, Heart Attack, Blood Pressure, Immunotherapy

Beta Blockers May Boost Immunotherapy, Help Melanoma Patients Live Longer

A common, inexpensive drug that is used to prevent heart attacks and lower blood pressure may also help melanoma patients live longer.

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Your Disease Risk, Substance Abuse Treatments, Comparing Lung Cancer Treatments, and More in the Healthcare News Source

The latest research, features and announcements in healthcare in the Healthcare News Source

Medicine

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St. Jude Children's Research Hospital, Acute Lymphoblastic Leukemia, High-Risk Leukemia, Journal Of Clinical Oncology, Leukemia germline variations, TP53 tumor suppressor gene , second cancers

Tumor Suppressor Gene Variants Identified as Cancer ‘Double Whammy’ for Leukemia Patients

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A study led by St. Jude Children’s Research Hospital found germline variations in a key tumor suppressor gene that may prompt changes in treatment and follow-up care for certain high-risk leukemia patients







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