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Medicine

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Kidney Failure Patients Face Hurdles, Sociology Expert, Subset Moves from Mother to Child, and More in the AIDS and HIV News Source

The latest research, features, and experts on HIV and AIDS.

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Shorter Radiation Use, BRCA Gene News, Staging Endometrial Cancer, and More in the Cancer News Source

Click here to go directly to the Cancer News Source

Medicine

Science

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Parents Grade Themselves, Signals from Fat, Getting Teens to Exercise, and More in the Obesity News Source

Click here to go directly to Newswise's Obesity News Source

Medicine

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Testosterone Treatment Improves Bone Density and Anemia, May Lead to Cardiac Risk

It is commonly known that testosterone levels decrease as men age, but until last year, little was known about the effects of testosterone treatment in older men with low testosterone. Today, in a group of papers published in the Journal of the American Medical Association (JAMA) and JAMA Internal Medicine, researchers found that testosterone treatment improved bone density and anemia for men over 65 with unequivocally low testosterone. However, testosterone treatment did not improve cognitive function, and it increased the amount of plaque buildup in participants’ coronary arteries.

Medicine

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Cancer, Prostate Cancer, Radiation, Cancer Treatment

Penn Expert Calls for Shorter Radiation Use in Prostate Cancer Treatment

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Men with prostate cancer can receive shorter courses of radiation therapy than what is currently considered standard, according to Justin Bekelman, MD, an associate professor of Radiation Oncology, Medical Ethics, and Health Policy at the University of Pennsylvania’s Perelman School of Medicine and Abramson Cancer Center.

Medicine

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Researchers Identify 'Achilles' Heel' of PTEN That Helps Drive Prostate Cancer Progression

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Loss of the protein Importin 11 predicts relapse and metastasis in patients following prostate removal

Medicine

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NanoVelcro, UCLA, liquid biopsies, Prostate Cancer, Nanowire, Cancer Moonshot, Hsian-Rong Tseng, PhD, Edwin Posadas, MD

Cedars-Sinai, UCLA Scientists Use New ‘Blood Biopsies’ With Experimental Device to Speed Cancer Diagnosis and Predict Disease Spread

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A team of investigators from Cedars-Sinai and UCLA is using a new blood-analysis technique and tiny experimental device to help physicians predict which cancers are likely to spread by identifying and characterizing tumor cells circulating through the blood.

Medicine

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Immune Cells, Mast Cells, Stress, Autoimmune Disease And Disorder, Allergies, Irritable Bowel Syndrome, Migraines, RNA, sex-specific associations , Gene Expression

Why Male Immune Cells Are From Mars and Female Cells Are From Venus

Michigan State University researchers are the first to uncover reasons why a specific type of immune cell acts very differently in females compared to males while under stress, resulting in women being more susceptible to certain diseases.

Medicine

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Prostate, Hormone, bicalutamide, GnRH agonists, Samuel Oschin

New Treatment Regimen Extends Life for Some Men With Recurrent Prostate Cancer, Study Finds

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Adding hormonal therapy to radiation treatment can significantly improve the average long-term survival of men with prostate cancer who have had their prostate gland removed, according to a new Cedars-Sinai study published in the Feb. 2 issue of the New England Journal of Medicine. The regimen also can reduce the frequency of spread of the cancer, the study found.

Medicine

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Prostate Cancer, radiotracers, Pet Scan, Cancer Diagnositics

New Radiotracer Could Make Diagnosing Prostate Cancer Faster and Easier

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Researchers at NIBIB have developed a new radiotracer to diagnose prostate cancer and conducted a successful Phase I clinical trial. Prostate cancer is the fifth leading cause of death worldwide and is especially difficult to diagnose. While prostate cancer is relatively easy to treat in its early stages, it is prone to metastasis and can quickly become deadly. In order to plan how aggressively they should treat the cancer, it is important for doctors to know how far the cancer has progressed. NIBIB researchers have attempted to solve this problem by developing a radiotracer that could identify prostate cancer at all stages.

Medicine

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Physiology, Heat Stress, Heat Exposure, Hyperthermia, Exercise capacity, Exercise Physiology, Exercise, Blood Flow

Whole-Body Heat Stress Lowers Exercise Capacity, Blood Flow in Men

Researchers have found that prolonged exposure to high temperatures can raise both the skin and core temperature, reducing blood flow to the brain and limbs during exercise and limiting the ability to exercise for long periods. The study, the first of its kind to separate the effects of skin- versus internal-raised temperature (hyperthermia), is published in Physiological Reports.

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Science

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Post Traumatic Stress Disorder, Alcohol Use Disorder, American Indian, Alaskan natives , Men and alcohol

Posttraumatic Stress and Alcohol Use Disorders Hit American-Indian and Alaskan-Native Men the Hardest

Posttraumatic stress disorder (PTSD) can develop after a traumatic event or events. Although it is most often associated with military personnel exposed to the trauma of combat, it can also disproportionately affect vulnerable American Indian and Alaskan-Native (AI/AN) populations. Because alcohol use disorders (AUDs) also have a disproportionate impact on AI/ANs, this study compared both lifetime PTSD and past-year AUD among AI/ANs and non-Hispanic Whites (NHWs).

Medicine

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Prostate Cancer, Blood Test, metasasis, Therapeutic Target

Predicting and Preventing Prostate Cancer Spread

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Australian researchers have uncovered a new pathway which regulates the spread of prostate cancer around the body. The discovery may lead to the development of a blood test that could predict whether cancer will spread from the prostate tumour to other parts of the body.

Science

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Molecule, Prostate Cancer, Roswell Park Cancer Institute

Can Prostate Cancer Metastasis Be Stopped Before It Starts? Research Team Identifies Role for Particular MicroRNA

Metastasis, or spread of a tumor from the site of origin to additional organs, causes the vast majority of cancer-related deaths, but our understanding of the molecular mechanisms behind metastasis remains limited. A research team led by Dean Tang, PhD, Chair of the Department of Pharmacology and Therapeutics at Roswell Park Cancer Institute, examined the multistep process that leads to metastasis and their work, which illuminates the role of prostate cancer stem cells that promote tumor growth and metastasis, has been published online ahead of print in the journal Nature Communications.

Life

Social and Behavioral Sciences

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One Night Stand Regrets

How we feel after 1-night stands has a lot to do with our gender -- and evolution.

Medicine

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Urology, Psa Test, Prostate Cancer

Ben Stiller's Surgeon Edward Schaeffer, MD Is Available to Discuss New Prostate Cancer PSA Testing Study

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Medicine

Life

Social and Behavioral Sciences

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Prostate Cancer, Emotional Distress, Overtreatment, University At Buffalo, Roswell Park Cancer Institute, Cancer, Journal Of Urology, Urology

Study: For Men with Prostate Cancer, Emotional Distress May Lead to More Aggressive Treatment

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The anxiety many men experience after being diagnosed with prostate cancer may lead them to choose potentially unnecessary treatment options, researchers from the University at Buffalo and Roswell Park Cancer Institute report in a new study.

Medicine

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Roswell Park, Prostate Cancer, androgen-deprivation therapy

Unique Gene Signature Predicts Potentially Lethal Prostate Cancers

Standard therapy for prostate cancer, the third-leading cause of cancer-related deaths in American men, is based on blocking androgens, the male sex hormones. However, for some men, prostate cancer recurs despite androgen-deprivation therapy. A team of scientists led by Irwin Gelman, PhD, Professor of Oncology in the Department of Cancer Genetics at Roswell Park Cancer Institute, has identified an 11-gene signature unique to advanced recurrent prostate cancer that they believe will help to identify these aggressive and potentially fatal prostate cancers sooner. The findings have been published online ahead of print in the journal Oncotarget.

Medicine

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Endocrine Society, Testosterone, testosterone assays, Laboratory Test, Men's Health, Healthcare Quality, Journal of Clinical Endocrinology and Metabolism

Landmark Study Defines Normal Ranges for Testosterone Levels

A large study of more than 9,000 men has established harmonized reference ranges for total testosterone in men that when applied to assays that have been appropriately calibrated will effectively enable clinicians to make a correct diagnosis of hypogonadism, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.

Medicine

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Cancer, Prostate Cancer, Psa Screening, Active Surveillance, overdiagnosis, Overtreatment

Prostate Cancer Treatment Rates Drop, Reflecting Change in Screening Recommendations

As some national guidelines now recommend against routine prostate cancer screening, the overall rate of men receiving treatment for the disease declined 42 percent, a new study finds.







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