Bioengineers have combined standard microscopy, infrared light, and artificial intelligence to assemble digital biopsies that identify important molecular characteristics of cancer biopsy samples.
Steven J. Miller, professor of mathematics at Williams College, has been selected as the 2020 Council on Undergraduate Research-Goldwater Scholars Faculty Mentor Awardee. The award consists of a plaque and $5,000 for the awardee’s research program and/or undergraduate researchers.
By: Rob Nixon | Published: April 2, 2020 | 3:13 pm | SHARE: A Florida State University researcher and her colleagues have earned a grant from the National Science Foundation to study the impact of the COVID-19 pandemic on public support for the rule of law. FSU Associate Professor of Political Science Amanda Driscoll, the project’s co-investigator, said the team will examine the challenge that the rapid spread of the novel coronavirus presents to long-standing norms that support democratic order.
Grant will develop and expand programing that will create a pipeline of early childhood education teachers.
Chirality is a type of asymmetry where something can’t overlap with its mirror image, like our hands. Michael Ostap, Ph.D., is researching what causes chirality on a molecular level to better understand embryonic development and how it can go wrong.
A potential COVID-19 vaccine, delivered by microscopic needles, produces antibodies specific to the virus when tested in mice. This is the first peer-reviewed paper describing a COVID-19 vaccine candidate. The next step is a human clinical trial.
PNNL scientist Garry Buchko is part of a nationwide network exploring the complex 3D structures of the 27 proteins of the novel coronavirus, each part of the molecular toolkit that the virus uses to infect, replicate and spread. Creating atomic-level pictures of the protein structures is a crucial first step toward mucking up the virus’s inner workings.
By mining a vast trove of genetic data,researchers at the University of Virginia School of Medicine are enhancing doctors’ ability to treat cancer, predict patient outcomes and determine which treatments will work best for individual patients. The researchers have identified inherited variations in our genes that affect how well a patient will do after diagnosis and during treatment.
The University of Kansas Cancer Center will receive an additional $5 million from the state budget for the KU Cancer Center Research Fund.
The Society for Laboratory Automation and Screening (SLAS) selected Thi Mui Pham, Ph.D., of the Julius Center for Health Sciences and Primary Care, University Medical Center - Utrecht (Utrecht, Netherlands) as its 2020 SLAS Visiting Graduate Researcher Grant recipient.
A team led by Pawel Kalinski, MD, PhD, of Roswell Park Comprehensive Cancer Center has earned a five-year, $14.54 million award from the National Cancer Institute (NCI) to expand a promising immunotherapy platform. Funded through the NCI’s Program Project Grant program, this prestigious five-year grant will fund five clinical trials, all focused on a strategy for making some of the most common immunotherapies work for more cancer patients.
Researchers invented a microfluidic chip containing cardiac cells that is capable of mimicking hypoxic and other conditions following a heart attack. The chip can be used to monitor electrophysiological and molecular response of the cells to heart attack conditions in real time.
Fiber optic cables, it turns out, can be incredibly useful scientific sensors. Researchers at Lawrence Berkeley National Laboratory have studied them for use in carbon sequestration, groundwater mapping, earthquake detection, and monitoring of Arctic permafrost thaw. Now they have been awarded new grants to develop fiber optics for two novel uses: monitoring offshore wind operations and underground natural gas storage.
La Jolla Institute for Immunology (LJI) has been awarded a $1.73 million grant by the Bill & Melinda Gates Foundation to establish a Coronavirus Immunotherapy Consortium (CoVIC) as part of the foundation’s global efforts to stem the tide of the current coronavirus outbreak.
Ulri Nicole Lee, Ph.D. candidate, (University of Washington) is the 2020 recipient of the SLAS Graduate Education Fellowship Grant. This is the fifth year the SLAS grant has been awarded to an outstanding student researcher.
University of Colorado Cancer Center group shows CPT1A may be necessary for ovarian cancer spread, chemo-resistance. Moves toward clinical trial of CPT1A inhibitor, etomoxir, against chemo-resistant ovarian cancer.
Highly focused, intense doses of radiation called stereotactic ablative radiation (SABR) may slow progression of disease in a subset of men with hormone-sensitive prostate cancers that have spread to a few separate sites in the body, according to results of a phase II clinical trial of the therapy.
During the fundamental process of mitosis, a type of cell division, dividing cells sometimes make errors while divvying up chromosomes. Understanding how this happens may help researchers develop targeted therapies for a variety of diseases, including cancer.
Researchers in the cancer nanomedicine community debate whether use of tiny structures, called nanoparticles, can best deliver drug therapy to tumors passively — allowing the nanoparticles to diffuse into tumors and become held in place, or actively — adding a targeted anti-cancer molecule to bind to specific cancer cell receptors and, in theory, keep the nanoparticle in the tumor longer. Now, new research on human and mouse tumors in mice by investigators at the Johns Hopkins Kimmel Cancer Center suggests the question is even more complicated.
The University of Delaware’s Jason Gleghorn, an assistant professor in biomedical engineering with a joint appointment in biological sciences, has received a National Science Foundation (NSF) Faculty Early Career Development Award to understand how the body's adaptive immune system activates. He said that he will use the five-year, $550,000 grant to develop a new class of microfluidic devices to culture an entire lymph node outside the body and study the cells’ behavior in real time.
With an estimated 1.7 million new cases and 600,000 deaths during 2017 in the U.S. alone, cancer remains a critical healthcare challenge. Researchers used the Comet supercomputer at the San Diego Supercomputer Center (SDSC) to evaluate their new molecular docking tool which aims to improve immunotherapy outcomes by identifying more effective personalized treatments.
A study of national dietary trends over 18 years finds some improvements in the diets of U.S. children, but the majority still have a poor-quality diet. Disparities persisted or even worsened, finds the study published in JAMA and led by researchers at Tufts.
Expressive language sampling yielded five language-related outcome measures that may be useful for treatment studies in intellectual disabilities, especially fragile X syndrome. The measures were generally valid and reliable across the range of ages, IQs and autism symptom severity of participants. According to the study, led by UC Davis researchers and funded by NIH, the measures are also functional in supporting treatments that can improve language, providing far reaching benefits for individuals with intellectual disabilities.
Researchers from UC San Diego and Brookhaven Laboratory in New York investigated a diverse population of meteorites. Among the 15 pieces of comets and asteroids studied, they found two with superconductive grains.
Children with aggressive blood cancers have differences — not just in the DNA code of their blood cells — but also in the heavily twisted protein superstructure that controls access to genes.
The U.S. Department of Energy (DOE) announced a plan to provide $60 million to establish multidisciplinary teams to develop new tools and techniques to harness supercomputers for scientific discovery.
Lipid droplets, membrane-bound packages of lipids, have been one of our cells’ least studied components. But recently, more scientists have begun probing the mysteries that surround them and finding fascinating results. James Olzmann, Ph.D., discusses how a protein on the surface of lipid droplets could be targeted to help treat cancer.
A team of University of California, Irvine researchers have published the first comprehensive overview of the major changes that occur in mammalian skin cells as they prepare to heal wounds. Results from the study provide a blueprint for future investigation into pathological conditions associated with poor wound healing, such as in diabetic patients.
Research to develop lightweight multifunctional metallic materials that can mimic structural properties in nature has won an assistant professor at The University of Alabama in Huntsville (UAH) a $540,000 National Science Foundation CAREER grant.
In light of the COVID-19 pandemic, Mercy Medical Center sought and received an Emergency Certificate of Need approval from the Maryland Health Care Commission to construct a new 32-bed acute care unit on the 17th floor of the hospital’s main inpatient facility, The Mary Catherine Bunting Center.
The National Science Foundation (NSF) recently awarded $8.2 million to the Woods Hole Oceanographic Institution (WHOI) to extend the life of the Overturning in the Sub-polar North Atlantic Program (OSNAP) in a key part of Earth’s ocean-climate system. The award is part of a $15.5 million grant to four U.S. institutions that will help add four years to the record being assembled by the observatory.
Nutrient cycling of stream ecosystems dependent on portion of salmons’ lifecycle.
Ziva Cooper, research director of the UCLA Cannabis Research Initiative, has been awarded a $3.9 million grant from the National Center for Complementary and Integrative Health at the NIH to study whether cannabis chemicals called terpenes can reduce the amount of opioid medication a person needs to reduce pain.
Researchers from the University of Kentucky’s College of Medicine are leading a clinical study that could provide a promising new method for early detection of Parkinson’s disease.
Bioengineers have created a 3D-printed scaffold designed to regenerate complex tissues composed of multiple layers of cells with different biological and mechanical properties.
Inspired by a tactic cancer cells use to evade the immune system, University of Pittsburgh researchers have engineered tiny particles that can trick the body into accepting transplanted tissue as its own, while leaving the immune system intact.
DHS S&T announced the grand prize winner of the Escape Respirator Prize Challenge.
A mechanical engineering professor from The University of Texas at El Paso will lend his expertise to early-stage space exploration technology research through a $550,000 grant from NASA to investigate the viability of power sources in the extreme temperatures of space.
Despite Mercury's 400 C daytime heat, there is ice at its caps, and now a study shows how that Vulcan scorch probably helps the planet closest to the sun make some of that ice.
Rutgers student Julia Van Etten, whose @Couch_Microscopy Instagram page garnered more than 25,000 followers by showcasing microorganisms as art, is now working with NASA on research into how red algae can help explain the origins of life on Earth.
Tens of thousands of reservoir and dam systems are being operated in communities across the United States, ensuring access to reliable sources of water. That access, however, isn’t a guarantee. Altered rainfall patterns driven by global warming, increased urbanization, and growing populations are setting up parallel increases in demand for water and energy. Sustainable approaches to managing these systems are a critical part of the solution. To that end, mechanical engineers at Rensselaer Polytechnic Institute are developing a better understanding of how water and sediment flow through reservoirs and dams, in the hopes of making that process closer to earth’s natural dynamics. Their work is being supported by a National Science Foundation Faculty Early Career Development (CAREER) grant.
The researchers have already confirmed their discovery in human tissue samples and used it to reverse high blood pressure in lab mice.
A room-temperature bonding technique for integrating wide bandgap materials such as gallium nitride (GaN) with thermally-conducting materials such as diamond could boost the cooling effect on GaN devices and facilitate better performance through higher power levels, longer device lifetime, improved reliability and reduced manufacturing costs.
People with serious mental illness report that poor physical health rather than their mental health condition creates barriers to job searching, according to a Rutgers study.
The American Society for Cell Biology wants to encourage scientists who have exhibited great promise early in their professional journeys with a variety of honorific awards. Below are several awards available to life scientists who are just beginning their careers—from graduate school through the first few years as a new investigator. Applications for all these awards open March 15.
More than 35 million Americans take statin drugs daily to lower their blood cholesterol levels. Now, in experiments with human cells in the laboratory, researchers at Johns Hopkins Medicine have added to growing evidence that the ubiquitous drug may kill cancer cells and have uncovered clues to how they do it.
Publishing in the March 16, 2020, online issue of Host, Cell and Microbe, a team of researchers at La Jolla Institute for Immunology, in collaboration with researchers at the J. Craig Venter Institute, provides the first analysis of potential targets for effective immune responses against the novel coronavirus. The researchers used existing data from known coronaviruses to predict which parts of SARS-CoV-2 are capable of activating the human immune system.
For teenagers with cystic fibrosis, maintaining a healthy weight can be a daily struggle. A psychology student is trying to make life easier for those teens.
Researchers from seven institutions team up to create a device combining artificial intelligence, bioelectronics and regenerative medicine for regrowing muscle tissue, especially after combat injuries.
GRF annual glaucoma research grants will support 12 investigators at prestigious colleges and universities across the United States.
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