Feature Channels: Genetics

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Released: 5-Apr-2021 4:15 PM EDT
Deep dive into key COVID-19 protein is a step toward new drugs, vaccines
Oregon State University

Researchers in the Oregon State University College of Science have taken a key step toward new drugs and vaccines for combating COVID-19 with a deep dive into one protein's interactions with SARS-CoV-2 genetic material.

Released: 5-Apr-2021 3:30 PM EDT
Overfishing of Atlantic Cod Likely Did Not Cause Genetic Changes
Rutgers University-New Brunswick

Overfishing likely did not cause the Atlantic cod, an iconic species, to evolve genetically and mature earlier, according to a study led by Rutgers University and the University of Oslo – the first of its kind – with major implications for ocean conservation.

Released: 2-Apr-2021 12:50 PM EDT
Unusual mechanism in rare mutation associated with Alzheimer’s uncovered by UChicago researchers
University of Chicago Medical Center

A novel mechanism has been identified that might explain why a rare mutation is associated with familial Alzheimer’s disease in a new study by investigators at the University of Chicago.

Released: 2-Apr-2021 10:45 AM EDT
Thirteen new Alzheimer's genes identified in first-of-its-kind human genome study
Massachusetts General Hospital

In the first study to use whole genome sequencing (WGS) to discover rare genomic variants associated with Alzheimer's disease (AD), researchers have identified 13 such variants (or mutations).

Released: 1-Apr-2021 3:15 PM EDT
New research on Alzheimer's Disease shows 'lifestyle origin at least in some degree'
Brigham Young University

For years, research to pin down the underlying cause of Alzheimer's Disease has been focused on plaque found to be building up in the brain in AD patients.

Released: 1-Apr-2021 2:55 PM EDT
Translation software enables efficient DNA data storage
Los Alamos National Laboratory

In support of a major collaborative project to store massive amounts of data in DNA molecules, a Los Alamos National Laboratory–led team has developed a key enabling technology that translates digital binary files into the four-letter genetic alphabet needed for molecular storage.

Released: 1-Apr-2021 2:45 PM EDT
Large study identified new genetic link to male infertility
ESTONIAN RESEARCH COUNCIL

The findings published in eLife show that men with this unstable subtype of the Y chromosome have a significantly increased risk of genomic rearrangements.

Released: 1-Apr-2021 12:55 PM EDT
Possible trigger for Crohn’s disease identified
McMaster University

AIEC bacteria grow in a biofilm that coats cells lining the intestinal wall, protecting them from both the immune system and antibiotics. In this research, the team identified a critical protein structure on the surface of the bacteria that allow them to grow in biofilms.

1-Apr-2021 10:00 AM EDT
Wistar Scientists Discover New Mechanism Through Which Senescent Cells Turn On Genes That Encode for Secreted Tumor-regulating Factors
Wistar Institute

Wistar scientists identified a new mechanism of transcriptional control of cellular senescence that drives the release of inflammatory molecules that influence tumor development through altering the surrounding microenvironment.

Released: 1-Apr-2021 8:50 AM EDT
Scientists Scour Genes of 53,000+ People to Better Battle Dangerous Diseases
University of Virginia Health System

International Project Set to Boost Precision Medicine, Reduce Health Disparities

Released: 31-Mar-2021 3:30 PM EDT
Scientists find genetic link to clogged arteries
Washington University in St. Louis

High cholesterol is the most commonly understood cause of atherosclerosis, a hardening of the arteries that raises the risk of heart attack and stroke. But now, scientists at Washington University School of Medicine in St. Louis have identified a gene that likely plays a causal role in coronary artery disease independent of cholesterol levels. The gene also likely has roles in related cardiovascular diseases, including high blood pressure and diabetes.

Released: 31-Mar-2021 2:25 PM EDT
CU Cancer Center Researcher Reveals New Effects of Oxygen Deprivation in Cancer Cells
University of Colorado Cancer Center

A team of University of Colorado School of Medicine researchers recently published a paper offering new insight into the role that oxygen deprivation, or hypoxia, plays in cancer development. CU Cancer Center member Joaquin Espinosa, PhD, is the senior researcher on the paper, which he hopes will help lead to more targeted treatments for cancer.

29-Mar-2021 11:55 AM EDT
‘Sweat sticker’ diagnoses cystic fibrosis on the skin in real time
Ann and Robert H. Lurie Children's Hospital of Chicago

A Northwestern University-led research team has developed a novel skin-mounted sticker that absorbs sweat and then changes color to provide an accurate, easy-to-read diagnosis of cystic fibrosis within minutes.

Released: 30-Mar-2021 10:10 AM EDT
Cleveland Clinic and IBM Unveil Landmark 10-Year Partnership to Accelerate Discovery in Healthcare and Life Sciences
Cleveland Clinic

Armonk, N.Y. and Cleveland, OH, March 30, 2021: Cleveland Clinic and IBM have announced a planned 10-year partnership to establish the Discovery Accelerator, a joint Cleveland Clinic - IBM center with the mission of fundamentally advancing the pace of discovery in healthcare and life sciences through the use of high performance computing on the hybrid cloud, artificial intelligence (AI) and quantum computing technologies.

   
Released: 30-Mar-2021 10:00 AM EDT
Researchers Develop New Method for Identifying Mutational Signatures in Cancer
Johns Hopkins Medicine

Researchers at the Johns Hopkins Kimmel Cancer Center used machine learning techniques to detect mutational signatures in cancer patients. Their algorithm outperformed the current standard of analysis and revealed new mutational signatures associated with obesity, which is believed by cancer prevention experts to be becoming the most significant lifestyle factor contributing to cancer in the U.S. and most of the Western world.

Released: 30-Mar-2021 9:00 AM EDT
Scientists Identify Molecular Pathway That Helps Moving Cells Avoid Aimless Wandering
Johns Hopkins Medicine

Working with fruit flies, scientists at Johns Hopkins Medicine say they have identified a new molecular pathway that helps steer moving cells in specific directions. The set of interconnected proteins and enzymes in the pathway act as steering and rudder components that drive cells toward an “intended” rather than random destination, they say.

Released: 29-Mar-2021 12:10 PM EDT
Apes show dramatically different early immune responses compared to monkeys
University of Chicago Medical Center

A new study out of the University of Chicago and the University of Illinois Urbana-Champaign in humans, chimpanzees, rhesus macaques and baboons has found key differences in early gene expression in response to pathogen exposure, highlighting the importance of choosing the right animal model for the right questions.

   
Released: 29-Mar-2021 10:40 AM EDT
New drug to regenerate lost teeth
Kyoto University

The tooth fairy is a welcome guest for any child who has lost a tooth. Not only will the fairy leave a small gift under the pillow, but the child can be assured of a new tooth in a few months. The same cannot be said of adults who have lost their teeth.

Released: 29-Mar-2021 10:00 AM EDT
MD Anderson’s Guillermina Lozano elected to Fellows of the AACR Academy
University of Texas MD Anderson Cancer Center

Guillermina (Gigi) Lozano, Ph.D., chair of Genetics at The University of Texas MD Anderson Cancer Center, has been elected to the 2021 class of Fellows of the American Association for Cancer Research (AACR) Academy in recognition of her pioneering work to describe the p53 tumor suppressor pathway, which is undermined in many cancers.

Released: 26-Mar-2021 2:05 PM EDT
Eat me: The cell signal of death
Kyoto University

Scientists at the Institute for Integrated Cell-Material Sciences (iCeMS) and colleagues in Japan have revealed molecular mechanisms involved in eliminating unwanted cells in the body.

   


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