The July issue is out! Find out the top reasons to read the July issue of Diseases of the Colon and Rectum.
A new study paves the way for the development of next generation therapeutics for the prevention and treatment of Clostridioides difficile infection (CDI), the most frequent cause of healthcare-acquired gastrointestinal infections and death in developed countries.
A study led by researchers at Washington University School of Medicine in St. Louis has identified a protein in the immune system that may protect babies from necrotizing enterocolitis, a leading cause of death among premature infants.
Physiologists at Laval University in Canada have discovered that diets containing low fiber and high fat cause significant shifts in the gut microbiome.
Summer picnics and barbecues are only a few weeks away! As excited as you are to indulge this summer, Escherichia coli bacteria are eager to feast on the all-you-can-eat buffet they are about to experience in your gut. However, something unexpected will occur as E. coli cells end their journey through your digestive tract. Without warning, they will find themselves swimming in your toilet bowl, clinging to the last bits of nutrients attached to their bodies.
GRAND RAPIDS, Mich. (JUNE 8, 2021) — Chronic inflammation in the gut may propel processes in the body that give rise to Parkinson’s disease, according to a study by scientists at Van Andel Institute and Roche.
A study by Mayo Clinic researchers provides some clarity in the use of direct oral anticoagulants (DOAC), such as apixaban and rivaroxaban, to treat acute venous thromboembolism (VTE) in patients with gastrointestinal cancers. The findings were published Wednesday, June 2, in Mayo Clinic Proceedings.
The June issue of AJG includes articles on the effectiveness of OTC therapies and green kiwifruit as a dietary therapy for chronic constipation, as well as new ACG Guidelines on the Prevention, Diagnosis, and Treatment of C. difficile infections, and more.
With COVD-19 restrictions loosening, people everywhere are contemplating going back to dining out and attending festivals. People with Celiac disease can join in – but must continue to be careful.
A new study published in Nature Communications demonstrates that a consortium of bacteria designed to complement missing or underrepresented functions in the imbalanced microbiome of inflammatory bowel disease (IBD) patients, prevented and treated chronic immune-mediated colitis in humanized mouse models.
Miguel Regueiro, M.D., has been named chair of Cleveland Clinic’s Digestive Disease & Surgery Institute (DDSI).
Infants exposed to thirdhand smoke while hospitalized in the neonatal intensive care unit (NICU) show a difference in the composition of their gut microbiome, according to a new study by researchers with The University of Texas Health Science Center at Houston (UTHealth).
The immune system's attempt to eliminate Salmonella bacteria from the gastrointestinal (GI) tract instead facilitates colonization of the intestinal tract and fecal shedding, according to National Institutes of Health scientists.
The June 2021 Issue of the Diseases of the Colon and Rectum is out! What are the top 11 reasons to read this month's issue?
Key guidance includes the diagnosis, management, and prevention of CDI, with a focus on diagnostic issues around diarrhea, distinguishing C. difficile colonization from active infection, and evaluation and management of CDI in IBD
Eating a Western diet impairs the immune system in the gut in ways that could increase risk of infection and inflammatory bowel disease, according to a study from researchers at Washington University School of Medicine in St. Louis and Cleveland Clinic.
In an important step toward the clinical application of synthetic biology, Rice University researchers have engineered a bacterium with the necessary capabilities for diagnosing a human disease.
Scientists at the National Institutes of Health determined that stomach inflammation is regulated differently in male and female mice after finding that androgens, or male sex hormones, play a critical role in preventing inflammation in the stomach. The study was published in Gastroenterology.
Artificial food colorants can cause disease when the immune system has become dysregulated, Icahn School of Medicine at Mount Sinai researchers report. The study, published in Cell Metabolism in May, was the first to show this phenomenon.
About 1 million people in the US suffer from ulcerative colitis, an inflammatory bowl disease that causes inflammation and sores in the digestive tract. Dr. Oleg Shulik worked with a patient to develop a holistic approach to treatment that allowed her to stop taking medications to manage her symptoms.
Research published in Nature reveals insights into how the body maintains balance with “good” gut bacteria that allows these microbes to flourish in the intestine but keeps them out of tissues and organs where they’re not supposed to be.
Scientists are rapidly gathering evidence that variants of gut microbiomes, the collections of bacteria and other microbes in our digestive systems, may play harmful roles in diabetes and other diseases.
AstaReal, pioneer and global leader in the production of natural astaxanthin, has always strived for excellence and advancement of natural astaxanthin research and product development.
A new study led by Washington University School of Medicine in St. Louis has found a link between drinking sugar-sweetened beverages and an increased risk of developing colorectal cancer in women under age 50. The findings suggest that heavy consumption of sugary drinks during adolescence (ages 13 to 18) and adulthood can increase the disease risk.
newly issued updates to ACG Clinical Guidelines on Upper Gastrointestinal and Ulcer Bleeding and Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury. In addition to the guidelines, this issue features clinical research on esophageal cancer, obesity, telemedicine, celiac disease, Crohn’s disease, and more.
WFIRM scientists are tackling necrotizing enterocolitis with a human placental-derived stem cell (hPSC) therapy strategy that is showing promising results.
Hackensack Meridian Mountainside Medical Center has announced Yong M. Kwon, M.D. as the hospital’s new division chief of gastroenterology, and Oleg Shulik, M.D. as subspecialty coordinator of gastroenterology.
Irritable bowel syndrome (IBS) is the most common gastrointestinal disorder, affecting 10-15% of the world’s population. Approximately two-thirds of those who suffer from IBS are women. The disease can have mild forms or cause severe debilitation as diarrhea alternates with constipation. Severe cramping and bloating also are common. Because chronic IBS is so debilitating, it often disrupts the daily lives of people with this disorder.
The May 2021 Issue of Diseases of the Colon and Rectum is out! Find out what's new
Clusters of a virus known to cause stomach flu are resistant to detergent and ultraviolet disinfection, according to new research co-led by Danmeng Shuai, Ph.D., an associate professor of civil and environmental engineering at the George Washington University and Nihal Altan-Bonnet, Ph.D., a senior investigator and the head of the Laboratory of Host-Pathogen Dynamics at the National Heart, Lung, and Blood Institute, part of the National Institutes of Health.
Also: Opioid prescription rates for GI conditions, evolving changes in fecal microbiota transplantation risk, endoscopy challenges in patients with surgically altered anatomy, insulin resistance and pancreatic cancer risk, comparing clinician and insurer perspectives to managing IBS, and more.
AIEC bacteria grow in a biofilm that coats cells lining the intestinal wall, protecting them from both the immune system and antibiotics. In this research, the team identified a critical protein structure on the surface of the bacteria that allow them to grow in biofilms.
The April edition of SLAS Technology features the cover article “Therapeutic Potential of Reactive Oxygen Species: State of the Art and Recent Advances” by Valeria Graceffa, Ph.D. (Institute of Technology Sligo, Sligo, Ireland).
A Northwestern University-led research team has developed a novel skin-mounted sticker that absorbs sweat and then changes color to provide an accurate, easy-to-read diagnosis of cystic fibrosis within minutes.
New study identifies a novel approach for tailored treatment that could be more effective for patients with the chronic disease
In a randomized clinical trial published in the journal PAIN, researchers found participants with moderate to severe irritable bowel syndrome (IBS) who were knowingly treated with a pharmacologically inactive pill — referred to as an honest or open-label placebo — reported clinically meaningful improvements in their IBS symptoms.
The American College of Gastroenterology Invites All to “Tune It Up: A Concert To Raise Awareness of Colorectal Cancer” Free Webstream Event Open to All on March 31, 2021 at 8:00 pm EDT
Studies suggest the gut microbiome can influence immunotherapy side effects. Butyrate emerges as an intriguing candidate against inflammation in the colon.
GI OnDEMAND®, gastroenterology’s leading multidisciplinary virtual integrated care platform today announced a partnership with Ambry Genetics®, a leading clinical genetic testing company, to integrate online genetic counseling and testing services into gastroenterology practices nationwide. This partnership addresses a critical clinical need for identifying hereditary GI cancer syndromes to help guide potentially life-altering health care decisions. GI OnDEMAND, a joint venture between the American College of Gastroenterology and Gastro Girl, Inc., will now offer the CARE (Comprehensive, Assessment, Risk, and Education) Program™ from Ambry Genetics.
A Cleveland Clinic-led team of researchers has discovered an infection that prevents healing in Crohn’s disease. According to study results published in Science, a type of yeast commonly found in cheese and processed meat is elevated in areas of unhealed wounds in Crohn’s disease patients, a discovery that may point to much-needed new treatment or prevention approaches for the common inflammatory bowel disease. The work was led by Thaddeus Stappenbeck, M.D., PhD., chair of Cleveland Clinic Lerner Research Institute’s Department of Inflammation and Immunity.
A foodborne fungus that is harmless to most people exacerbates gastrointestinal symptoms in people with Crohn’s disease by preventing intestinal ulcers from healing, according to a new study from Washington University School of Medicine in St. Louis and the Cleveland Clinic. The findings suggest that antifungal medications or dietary interventions may help alleviate the symptoms of Crohn’s.
Recently, Prof. ZHU Shu from University of Science and Technology of China (USTC) of CAS and Prof. Richard A. Flavell from Yale University were invited to publish a review article in Nature Reviews Gastroenterology and Hepatology.
The March issue of The American Journal of Gastroenterology features new clinical research involving sex and gender, including effects of GI and liver conditions on pregnancy, gender disparities in diet and nutrition, Barrett’s esophagus incidence in women with scleroderma, factors influencing whether women pursue advanced endoscopy careers, endoscopy-related musculoskeletal injuries, sex hormone association with increased prevalence of certain types of cancer, and more.
The American College of Gastroenterology has issued updated evidence-based screening guidelines for colorectal cancer (CRC), including a new recommendation to begin CRC screening at age 45 for average risk adults. Key updates include recommendations for screening individuals with family history of CRC or polyps, guidance on the use of aspirin to reduce the risk of CRC, quality indicators for adenoma detection rate and colonoscopy withdrawal time, as well as suggestions about evidence-based interventions to boost screening rates, especially among African Americans. The authors distinguish between one-step screening tests, such as colonoscopy, and two-step screening tests that require colonoscopy, if positive, in order to complete the screening process.
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