Researchers at UT Southwestern Medical Center have found that a molecule produced naturally by muscles in response to nerve damage can reduce symptoms and prolong life in a mouse model of amyotrophic lateral sclerosis (ALS).
Results of a preliminary study by scientists at the National Institutes of Health and Johns Hopkins show that “mini” stem cell transplantation may safely reverse severe sickle cell disease in adults.
A new study shows strong relationships between personality traits and medical school performance.
Challenges associated with spaceflight do not end with landing. Astronauts often suffer from dizziness and have difficulty standing and walking after landing on Earth. Researchers are developing techniques using a treadmill to help the astronauts adapt to the return to gravity. The techniques may benefit non-astronaut groups such as the elderly.
The Methodist Hospital System became the first in Houston this month to use new technology that dramatically reduces CT radiation doses without compromising the quality of the image.
The testing of DNA from a statewide blood screening program for newborns in Wisconsin was able to identify infants with T-cell lymphopenia, a blood disorder that affects the child’s immune system, a disease in which early identification is important, according to a study in the December 9 issue of JAMA.
Most primary care physicians active in the Medicare program work in practices with too few patients to reliably measure significant differences in common measures of quality and cost performance, according to a study in the December 9 issue of JAMA.
Patients with a cluster headache, which is characterized by bouts of excruciating pain usually near the eye or temple, were more likely to report being pain-free within 15 minutes of treatment with high-flow oxygen than patients who received a placebo treatment, according to a study in the December 9 issue of JAMA.
Approximately 20 percent of dialysis patients undergoing a percutaneous coronary intervention (PCI; procedure such as angioplasty) are given an antithrombotic medication they should not receive, which may increase their risk for in-hospital bleeding, according to a study in the December 9 issue of JAMA.
Blood vessel blockage, a common condition in old age or diabetes, leads to low blood flow and results in low oxygen, which can kill cells and tissues. Such blockages can require amputation resulting in loss of limbs. Now, using mice as their model, researchers at Johns Hopkins have developed therapies that increase blood flow, improve movement and decrease tissue death and the need for amputation.
From MRSA to prostate cancer, Henry Ford Hospital in Detroit is offering a snap-shot of its latest medical research news. News items have been recently published or presented at major medical conferences; all items include a link to the full article.
A new article published in the peer-reviewed journal Women’s Health emphasizes the importance of early pregnancy detection. Using research conducted on behalf of Church & Dwight Co. Inc., the makers of First Response, the article reviews data that shows not all at-home pregnancy tests are created equal –First Response® brand pregnancy tests are more sensitive and able to detect key variants of the pregnancy hormone better than other at home pregnancy tests.
Defibrotide, a novel drug which modulates the response of blood vessels to injury, was markedly more effective than standard treatment in post-stem cell transplant patients with hepatic veno-occlusive disease, a life threatening toxicity of transplant caused by blockages in tiny blood vessels of the liver, according to a study led by Dana-Farber Cancer Institute scientists.
A multi-institutional team of researchers has begun creating genomic tools necessary to compare the extraordinary regenerative capacity of the salamander with mouse models of human disease and injury.
Neurology researchers have shown that feeding amino acids to brain-injured mice restores their cognitive abilities and may set the stage for the first effective treatment for cognitive impairments suffered by people with traumatic brain injuries. Every 23 seconds, a man, woman or child in the U.S. suffers a traumatic brain injury.
A first-in-its class oral medication provides significant and durable relief for patients with a rare, debilitating and lethal bone marrow disorder called myelofibrosis, researchers at The University of Texas M. D. Anderson Cancer Center reported today at the 51st Annual Meeting of the American Society of Hematology.
Cholesterol-lowering drugs known as statins are among the most prescribed medicines in the U.S. Now a new study by researchers at Fred Hutchinson Cancer Research Center indicates that statins may protect stem cell transplant patients from one of the most serious complications of the life-saving cancer therapy: graft-versus-host disease, or GVHD. The findings are reported in the Nov. 4 first edition of the journal Blood.
Human guinea pigs do their homework before volunteering for high-paying clinical trials. New research shows that people equate large payments for participation in medical research with increased levels of risk. And when they perceive studies to be risky, potential participants spend more time learning about the risks and nature of the study. Findings published this month in Social Science and Medicine, suggest there is a "mismatch" between current research guidelines for setting compensation levels and the assumptions participants make about the levels of pay and risk.
Thanks to Los Angeles County’s new Emergency Stroke System, individuals who experience a stroke may now be able to more quickly access some of the latest advances in stroke interventions. The Emergency Medical Services Agency announced that ambulances will transport suspected stroke patients directly to Approved Stroke Centers in Los Angeles County. These are facilities that are specially stroke-prepared – medically and surgically – and have the mechanisms in place to quickly provide the right treatment.
The severity of injury and level of impairment -- not the workers' legal fees -- have the most effect on payout for workers' compensation claims among Illinois construction workers, researchers at the University of Illinois at Chicago School of Public Health have found.
A new model can help physicians determine if a kidney disease patient on dialysis is likely to die within the next few months, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). This clinical tool could help medical professionals initiate discussions with patients and their families about end-of-life care such as hospice.
Physicians should “throttle back” from routinely ordering stress tests and prescribing beta blockers to patients before non-cardiac surgeries, according to a report by the University of Michigan released online this week.
The chance of surviving an out-of-hospital cardiac arrest has not improved since the 1950s, according to research by the University of Michigan Health System. Only 7.6 percent of victims survive an out-of-hospital cardiac arrest.
Many people rely on continuous positive airway pressure (CPAP) machines as a safe and effective treatment for sleep apnea. But a new case report describes a rare complication—a lingering inflammatory disease of the lungs, apparently related to the use of contaminated well water in a CPAP machine.
Peripheral artery disease (PAD) affects 5 million individuals in the U.S. and is the leading cause of limb amputations. Doctors have long considered exercise to be the single best therapy for PAD, and now a new study led by researchers at Beth Israel Deaconess Medical Center helps explain why.
Research engineers have discovered that a bundled “cap” of thread-like fibers holds cell nuclei in their proper places.
Add guitars and other musical instruments to the tools caregivers can use to help patients in hospice care. That’s what University of Alabama senior Sarah Pitts found when she brought her music therapy skills to patients.
Preliminary research suggests that criteria based on computed tomography (CT) imaging of changes in tumors from colorectal liver metastases after chemotherapy with the drug bevacizumab may have the potential to predict overall survival, according to a study in the December 2 issue of JAMA.
African-Americans with preventable conditions often fail to get adequate care, resulting in hospitalizations years earlier than whites with the same conditions, results from a new study suggest.
People can survive cardiac arrest if they receive only chest compressions during attempts to revive them. But they cannot survive without access to oxygen sometime during the resuscitation effort, research suggests.
Physicians at UT Southwestern Medical Center soon will begin implanting a new device designed to improve breathing in patients with upper spinal-cord injuries or other diseases that keep them from breathing independently.
When you eat may be just as vital to your health as what you eat, found researchers at the Salk Institute for Biological Studies. Their experiments in mice revealed that the daily waxing and waning of thousands of genes in the liver—the body’s metabolic clearinghouse—is mostly controlled by food intake and not by the body’s circadian clock as conventional wisdom had it.
Patients with an out-of-hospital cardiac arrest who received intravenous (IV) drug administration during treatment, recommended in life support guidelines, had higher rates of short term survival but no statistically significant improvement in survival to hospital discharge or long-term survival, compared to patients who did not receive IV drug administration, according to a study in the November 25 issue of JAMA.
Nearly 90 percent of medical journals with relatively high impact factors have policies addressing author conflict of interest (COI) available for public review, according to a report in the November 25 issue of JAMA. But many journals do not require authors to sign disclosure statements, and there is variability in how COI is defined.
It was 25 years ago that Baylor Health Care System chose to perform a highly publicized liver transplant on five-year-old Amie Garrison, a personal ward of then-First Lady Nancy Reagan.
Thursday is National Family History Day. A team of researchers at the University of Virginia announces it is enhancing a Web site called Health Heritage®, which will allow families to track and share their medical histories.
The University of Southern California (USC) University Hospital received a Heart Transplant Excellence Award from the independent healthcare ratings organization Health Grades, ranking among the top one percent of hospitals in the U.S. that perform heart transplants.
Previous research has demonstrated links between urban sprawl and many of our most pressing public health issues, including obesity and traffic injuries. New research from the University of Virginia Health System shows that urban sprawl also causes delays in ambulances reaching their destinations in sprawling sections of large metropolitan areas in the United States.
Patients whose hypertension is managed by a physician-pharmacist team have lower blood pressure levels and are more likely to reach goals for blood pressure control than those treated without this collaborative approach, according to a report in the November 23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Clinical trial data indicated an association between the anti-inflammatory medication rofecoxib and cardiovascular risk as early as December 2000, before the product was taken off the market in September 2004, according to a report in the November 23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
A large study of more than 1,300 patients has provided evidence that increased attention to pain assessment in mechanically ventilated patients in the intensive care unit may improve patient outcomes and lead to shorter ICU stays.
Point-of-care testing may help curb the rising numbers of STD cases. The CDC estimates that approximately 19 million new STD infections occur each year. Approximately half of them occur in young people between 15 to 24 years of age.
A protein known to stimulate blood vessel growth has now been found to be responsible for the cell overgrowth in the development of polyps that characterize one of the most severe forms of sinusitis, a study by Johns Hopkins researchers suggests. The finding gives scientists a new target for developing novel therapies to treat this form of the disease, which typically resists all current treatments.
Surgeons who are burned out or depressed are more likely to say they had recently committed a major error on the job, according to the largest study to date on physician burnout. The new findings suggest that the mental well-being of the surgeon is associated with a higher rate of self-reported medical errors, something that may undermine patient safety more than the fatigue that is often blamed for many of the medical mistakes.
Health systems should consider pharmacy-based interventions when involving patients who have poor follow-through taking medication. That’s according to a study appearing today in the online edition of Schizophrenia Bulletin. The study was led by Marcia Valenstein, M.D., Senior Research Scientist in the VA Health Services Research and Development Service and Associate Professor in the Department of Psychiatry at the U-M Medical School.
Worldwide, more than 450 million people live with unmet mental health care needs. Wake Forest University Counseling Professor Donna Henderson co-developed a training course with easy-to-follow lessons that helps nonprofessional community volunteers in developing countries respond to mental health issues.
Sleep apnea is common in individuals who receive a kidney transplant and is associated with increased risk of high blood pressure, heart disease or stroke, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). Researchers found that kidney transplant patients are just as likely to have this sleep disorder as dialyzed kidney disease patients who are on the transplant waiting list. Therefore, both types of patients who have sleep apnea should be considered at high risk for developing serious heart-related complications.
Cigarettes are "widely contaminated" with bacteria, including some known to cause disease in people, concludes a new international study conducted by a University of Maryland environmental health researcher and microbial ecologists at the Ecole Centrale de Lyon in France.
Scientists in China are reporting discovery of unusual liver proteins, found only in males, that may help explain the long-standing mystery of why the hepatitis B virus (HBV) sexually discriminates -- hitting men harder than women. Their study has been published online in ACS’ Journal of Proteome Research, a monthly publication.
In an advance with overtones of Star Trek phasers and other sci-fi ray guns, scientists in Canada are reporting development of an internal on-off “switch” that paralyzes animals when exposed to a beam of ultraviolet light. The animals stay paralyzed even when the light is turned off. When exposed to ordinary light, the animals become unparalyzed and wake up.
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