Reprogrammed Stem Cell-Derived Neurons Survive Long-Term in Pigs with Spinal Cord Injuries
UC San Diego HealthIn a new paper, publishing Mary 9 in Science Translational Medicine, an international team led by scientists at University of California San Diego School of Medicine describe successfully grafting induced pluripotent stem cell (iPSC)-derived neural precursor cells back into the spinal cords of genetically identical adult pigs with no immunosuppression efforts. The grafted cells survived long-term, displayed differentiated functionality and caused no tumors.