Data presented from a Late-Breaking Clinical Trial has the potential to change the standard of care for HER2-positive breast cancer patients undergoing chemotherapy.
Patients who receive cardiac positron emission testing (PET) imaging instead of single photon emission computed tomography (SPECT) scan experienced a significant increase in the detection of severe obstructive coronary artery disease, according to researchers at the Intermountain Medical Center Heart Institute in Salt Lake City.
ORLANDO: Cleveland Clinic researchers found that implementing a four-step protocol for the most severe type of heart attack not only improved outcomes and reduced mortality in both men and women, but eliminated or reduced the gender disparities in care and outcomes typically seen in this type of event. The research was presented at the American College of Cardiology’s 67th Annual Scientific Session and published in the Journal of the American College of Cardiology.
The absence of TTP, a protein critical to the control of inflammation, may lead to rapid and severe bone loss, according to a new study led by the University at Buffalo.
A UNLV scientist has discovered the first direct evidence that fluid water pockets may exist as far as 500 miles deep into the Earth’s mantle.
Tufts biologists have demonstrated for the first time that electrical patterns in developing embryos can be predicted, mapped and manipulated to prevent defects caused by harmful substances such as nicotine. The study suggests that targeting bioelectric states may be a new treatment modality for regenerative repair in brain development and disease.
High-altitude areas—particularly the US intermountain states—have increased rates of suicide and depression, suggests a review of research evidence in the Harvard Review of Psychiatry. The journal is published by Wolters Kluwer.
Researchers at Iowa State University, partnering with the LifeServe Blood Center, have used leftover blood donor cells to gain crucial insights into how natural killer cells circulating in the human body differ from those typically studied in the lab. The results of this research are published in the March 9 issue of the Journal of Biological Chemistry.
A team led by engineers at Tufts University has opened a window into the cell by developing an optical tool that can read metabolism at subcellular resolution. The researchers were able to use the method to identify specific metabolic signatures that could arise in diabetes, cancer, cardiovascular and neurodegenerative diseases.
Illnesses and injuries associated with working in Illinois mines are substantially underreported to the federal agency tasked with tracking these events, according to a new study published in the American Journal of Industrial Medicine.The U.S. Department of Labor’s Mine Safety and Health Administration requires reporting of injuries and illness sustained while working in mines in the U.
Researchers found that the fruit fly blood brain barrier has a molecular clock that makes it more penetrable during certain hours of the day. Giving mutant flies a drug for treating seizures at night was more effective.
Argonne researchers have found that in the next 100 years, already existing reforestation in the country could help topsoil absorb an additional 2 billion tons of carbon. Their work is detailed in a recent study in the Proceedings of the National Academy of Sciences.
Un nuevo estudio de Mayo Clinic plantea que hasta el 97 por ciento de los pacientes no se incomodan cuando los proveedores de atención médica les preguntan acerca de su orientación sexual e identidad de género.
Children with mitochondrial diseases who suffered acute metabolic strokes benefited from rapid intravenous treatment with the amino acid arginine, experiencing no side effects from the treatment. In half of the stroke episodes, patients showed clinical improvements in symptoms such as seizures and partial paralysis.
Use of tests that assess genomic variants in circulating tumor DNA (ctDNA) is on the rise. A new joint review from the American Society of Clinical Oncology (ASCO) and the College of American Pathologists (CAP) provides an assessment of evidence on ctDNA tests in oncology.
New Mayo Clinic research suggests up to 97 percent of patients are comfortable with their health care provider asking sexual orientation and gender identity questions. Before this research, it was unclear if the questions – which researchers say are important to reduce health disparities among LGBTI patients – would offend patients. The findings were published today in Health Services Research.
VR has shown promise in several clinical trials assessing its possible utility as a distraction tool to alleviate pain and distress during medical procedures.
Working with mice, Johns Hopkins researchers report they have found previously known skin itch receptors in the airways that appear to contribute to bronchoconstriction and airway hypersensitivity, hallmarks of asthma and other respiratory disorders. The investigators’ experiments in mice suggest that the receptors’ activation directly aggravates airway constriction and—if the same process is active in people—may be a promising new target for the development of drug therapies.
Research from a collaborative team at Washington University in St. Louis tested a 3-D method that could lead to new diagnostic tools that will precisely measure the third-trimester growth and folding patterns of a baby’s brain. Their findings might help to sound an early alarm on developmental disorders in preemies that could affect them later in life.
According to a new study by The Wistar Institute, EZH2 inhibitors that are currently in clinical development for hematological malignancies and solid tumors may be effectively targeted to epithelial ovarian cancers overexpressing the CARM1 protein.
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