Vitamin C may reduce the harm done to lungs in infants born to mothers who smoke during their pregnancy, according to a randomized, controlled trial published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.
TB meningitis causes life-threatening inflammation of the brain, which is difficult to treat due to the inability of drugs to penetrate the blood brain barrier. Researchers used PET imaging to measure antibiotic concentrations in infected brains with the goal of optimizing TB meningitis treatment.
Although relatively rare in the United States, and accounting for fewer than 5 percent of tuberculosis cases worldwide, TB of the brain—or tuberculosis meningitis (TBM)—is often deadly, always hard to treat, and a particular threat to young children.
In a new study published in the Journal of Experimental Medicine, scientists at the University of Notre Dame have discovered that the pathogen Mycobacterium tuberculosis (MTB) releases RNA into infected cells.
Researchers show that lung-resident memory B cells establish themselves in the lung soon after influenza infection in mice. Those lung memory B cells respond more quickly to produce antibodies against influenza after re-infection, and establishment requires a local antigen encounter in the lung.
It is an often case that one’s health and life depend on as quick a disease is found. That is why today the ways of quick and effective revealing of a disease is one of the most important directions in medicine.
Description: Papers on BPA and phthalates; EDCs and obesity; air pollution; respiratory outcomes in deployed soldiers; and miRNAs featured in latest issue of Toxicological Sciences.
Conrad Tucker, associate professor of engineering design and industrial engineering, demonstrates how a mobile-based application will use a cellphone camera and computer vision techniques to capture pulse rate. Tucker and his team use a Masimo Rad-97, a compact, portable patient monitoring device which measures pulse rate, respiratory rate, oxygen saturation, perfusion index, total hemoglobin and pleth variability index, as a ground to compare the application's captured data.
Researchers at Moffitt Cancer Center are trying to devise alternative mechanisms to block KRas. Their recent study demonstrates that the protein GSK3 is an important mediator of KRas-dependent tumor viability. Their research was published today in Nature Communications.
New research from Cornell University suggests graphic warning labels on cigarette ads have the same anti-smoking effect as similar warning labels on cigarette packs.
Pinellas County residents and visitors who are susceptible to the respiratory impacts of Florida's red tide -- especially people with asthma and other chronic lung diseases -- now have a new tool that will help them know their risks before they visit area beaches during red tides.
A new clinical trial at The University of Texas Health Science Center at Houston (UTHealth) is the first in the world to investigate whether infusing an infant’s own umbilical cord blood cells, or autologous cells, can protect the brain, mitigating the risk of neurodevelopmental challenges in babies with severe congenital diaphragmatic hernia (CDH).
In an era of personalized medicine, physicians treating patients with chronic obstructive pulmonary disease (COPD) should consider individualized therapy depending on disease severity and the cost and availability of medications. However, some physicians may not be as informed as they would like to be about which inhalation devices for COPD are best for which patients, according to a survey designed by American Thoracic Society (ATS) clinicians and scientists and conducted by Harris Poll, which was published in the July issue of Respiratory Care.
Middle-aged adults with lung disease may be at greater risk of developing dementia or cognitive impairment later in life, according to new research published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.
Rush University Medical Center has opened a center for airway diseases, a comprehensive program to treat people with interrelated chronic conditions such as sinusitis, allergies, asthma and sleep apnea, which affect millions of people. It is the first program of its kind in Illinois.
A study including health data for more than 500,000 children in the U.S. suggests obesity might be to blame for about a quarter (23 to 27 percent) of asthma in children who are obese.
This could mean about 10 percent of all kids ages 2 to 17 with asthma -- almost 1 million children in the U.S. -- might have avoided the illness by maintaining a healthy weight, according to researchers at Duke University and collaborators with the National Pediatric Learning Health System (PEDSnet).
Hantaviruses cause severe and sometimes fatal respiratory infections, but how they infect lung cells has been a mystery. In today’s issue of Nature, an international team including researchers at Albert Einstein College of Medicine reports that hantaviruses gain entry to lung cells by “unlocking” a cell-surface receptor called protocadherin-1 (PCDH1). Deleting this receptor made lab animals highly resistant to infection. The findings show that targeting PCDH1 could be a useful strategy against deadly hantavirus pulmonary syndrome (HPS).
About half of all people with cystic fibrosis, the most common genetic disorder in the United States, die from a lung disease before they turn 40. A form of pneumonia called Pseudomonas aeruginosa is a likely culprit. WVU researcher Mariette Barbier is pursuing new ways to vaccinate at-risk populations against this deadly illness.
Johns Hopkins Medicine researchers report that a program designed to enhance self-care and lead to more seamless management of chronic obstructive pulmonary disease (COPD) in adults successfully reduced rates of emergency room visits and hospitalization, and the burdensome symptoms and limitations caused by the condition.
New research shows children of caregivers with poor asthma knowledge were four times more likely to have a prolonged hospital stay. A “prolonged” stay was defined as more than two days.
In response to today’s shocking data from the CDC documenting a 78 percent increase e-cigarette use among high schoolers and a 48 percent increase among middle schoolers, the FDA is finally taking concrete action to regulate tobacco products.
The American Thoracic Society strongly supports the initial announcement, but more concrete action is needed.
Patients with fibromyalgia who use tobacco products are at greater risk for cognitive impairment and other symptoms that affect quality of life, according to the results of a study from the Mayo Clinic in Rochester, MI.
The study, led by UCLA professors Claudio Scafoglio and David Shackelford, suggests that a biomarker can help scientists detect lung cancer earlier, when it is much easier to treat.
The Mayo Clinic Cancer Center has received a supplemental grant from the National Cancer Institute to ensure that all cancer patients who use tobacco have access to treatment for their tobacco use.
The National Institutes of Health awarded Tulane University School of Medicine a contract for up to $8.5 million over five years to develop a more effective and longer-lasting vaccine against pertussis, more commonly known as “whooping cough.”
Using freshly resected lung tissue from 21 patients and two distinct mouse models, tuberculosis researchers at the University of Alabama at Birmingham and the Africa Health Research Institute have identified a protein that plays an essential role in host defense against this deadly disease.
Only a tiny fraction of patients hospitalized for COPD, or chronic obstructive pulmonary disease, participate in a pulmonary rehabilitation program following hospitalization, even though such programs are recommended and Medicare covers their cost, according to new research published online in the Annals of the American Thoracic Society.
The American Thoracic Society is gravely concerned and disappointed in the FDA’s decision to approve over the counter epinephrine (Primatene Mist HFA) for consumer use to treat asthma. The ATS is a medical professional society dedicated to the prevention, detection, treatment and research of pulmonary disease, critical care illness and sleep disordered breathing. Our members are experts in the diagnosis and management of asthma and have published several clinical practice guidelines for the treatment of asthma. It is with our extensive clinical expertise in the treatment of asthma and our concern for the patients that we oppose the FDA’s decision.
Babies with cystic fibrosis may breathe better by inhaling hypertonic saline, according to a randomized controlled trial conducted in Germany and published in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.
The American College of Allergy, Asthma and Immunology warns those with asthma not to stop using their prescription medications in favor of Primatene Mist.
Experimenting with mice, Johns Hopkins Medicine researchers have added to evidence that a hormone best known for helping regulate hunger and body weight might also ease breathing problems experienced during sleep more effectively when given through the nose.
To support the the American Cancer Society's Great American Smokeout, Quit & Stay Quit Monday, an initiative of The Monday Campaigns and the Institute for Global Tobacco Control at the Johns Hopkins University Bloomberg School of Public Health, are introducing a new “Monday Quit Kit” for individuals and tobacco cessation professionals that can help quitters stay on track over the long haul.
A Rutgers Cancer Institute of New Jersey researcher has received a $150,000 grant from the Lung Cancer Research Foundation to investigateautophagy in the development of lung cancers driven by mutations in tumor suppressors known as LKB1 and oncogene KRAS.
In research to improve influenza therapies against H7N9 and other influenza strains, Chad Petit and colleagues have detailed the binding site and mechanism of inhibition for two small-molecule experimental inhibitors of influenza viruses. Their report is published in the Journal of Biochemistry,
“Think globally, act locally” is a popular global health idea that encourages people to consider the health of the entire planet while taking actions in their own cities and communities. And it’s an idea that inspired a group of students in the Perelman School of Medicine to join with other medical schools in Philadelphia and start a group dedicated to the growing field of global surgery. Until recently, surgery has been largely omitted from global health efforts, taking a back seat to infectious diseases like HIV/AIDS, tuberculosis, and malaria. But as progress is made to treat and prevent these diseases, it has become clear that there is a significant need to focus on treating people in resource-limited settings who are in need of surgical care. And this need touches almost every aspect of health care from cancer to obstetrics to orthopedics. In fact, according to the Lancet Commission on Global Surgery, more than 18 million people die each year from lack of surgical care.
Whether they are smokers or not, people living in poor, rural areas of the United States are more likely to have COPD, or chronic obstructive pulmonary disease, according to research published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.
The American Thoracic Society and the American Lung Association’s LUNG FORCE initiative have launched a new website and online toolkit to help medical institutions implement and manage a lung cancer screening program.
Vanderbilt researchers, as part of the International Human Vaccines Project, are searching for the key to lasting protection against influenza by examining naturally protecting cells found in bone marrow.
El aceite de geranio rosa puede aliviar los síntomas de la vestibulitis nasal, afección común y dolorosa de la nariz que se vincula con el tratamiento farmacológico contra el cáncer, según indican los resultados de un estudio observacional publicado por Internet en BMJ Supportive & Palliative Care.
In the U.S., lung cancer remains the leading cause of cancer death among both men and women. The primary reason for high death rates for lung cancer is the fact that this disease is typically detected in very late stages. A Rutgers University expert weighs in on new screening resources to combat the disease.
Adding radiation therapy or surgery to systemic therapy for stage IV lung cancer patients whose cancer has spread to a limited number of sites can extend overall survival time significantly, according to new results from a multicenter, randomized, controlled phase II study. The findings were presented last week at the 60th Annual Meeting of the American Society for Radiation Oncology (ASTRO).