The University of Pennsylvania School of Nursing and the New York Blood Center, in partnership with local community consulting groups, have received a $769,578 grant from the National Institute of Mental Health to embark on designing an awareness program on the usage of the daily oral medication Pre-Exposure Prophylaxis (PrEP).
Researchers have made significant progress in the development of a potential vaccine to protect against HIV infection.
When HIV attacks a T cell, it attaches itself to the cell’s surface and launches a “harpoon” to create an opening to enter and infect the cells. To stop the invasion, researchers from the Penn Center for AIDS Research at the University of Pennsylvania and scientists from Sangamo BioSciences, Inc. have developed genetically engineered T cells armed with a so-called “fusion inhibitor” to disrupt this critical step and prevent a wide range of HIV viruses from entering and infecting the T cells. The findings were reported today online in a preclinical study in PLOS Pathogens.
Scientists from around the world will gather at UAB in December to focus on HIV research and women, particularly collaborative research on women living with HIV and those at risk.
Researchers at the University of Louisville School of Public Health and Information Sciences have developed a tool for framing the relationship between policy, criminal justice practices and HIV-related factors that impact racial disparities.
GW researchers received a $2.2 million grant from the National Cancer Institute to uncover why certain cancer types increase whereas others are unchanged or even decrease in those with HIV infection.
A study led by researchers at Beth Israel Deaconess Medical Center (BIDMC), in collaboration with scientists at Walter Reed Army Institute of Research (WRAIR), Janssen Vaccines & Prevention B.V., one of the Janssen Pharmaceutical Companies of Johnson & Johnson and Gilead Sciences, Inc., has demonstrated that combining an experimental vaccine with an innate immune stimulant may help lead to viral remission in people living with HIV. In animal trials, the combination decreased levels of viral DNA in peripheral blood and lymph nodes, and improved viral suppression and delayed viral rebound following discontinuation of anti-retroviral therapy (ART). The research team’s findings appeared online today in the journal Nature.
Immunotherapy has revolutionized treatment options in oncology, neurology, and many infectious diseases and now there is fresh hope that the same method could be used to treat or even functionally cure HIV, according to two related studies from Perelman School of Medicine at the University of Pennsylvania, the University of Alabama at Birmingham (UAB), and the National Institutes of Health (NIH).
Antibody VRC01 proves safe for individuals infected with HIV-1 but only modestly controls the virus in participants who stop receiving antiretroviral therapy.
As the world moves toward universal health coverage, the question arises: How can governments ensure equitable access to essential medicines in low- and middle-income countries? A section of The Lancet Commission on Essential Medicines Policies report, released today, finds that funding for a “basket” of these essential medicines may pose a challenge, but not necessarily an insurmountable one, for the global health community.
A new technique to cheaply and rapidly create sets of DNA fragments that include all possible genetic variants will help scientists distinguish between genetic variants linked to disease and those that are innocuous.
• New research suggests that transmembrane TNF-alpha may allow HIV to infect kidney cells that not express the major HIV-1 CD4 receptor. The findings could provide insights on how patients develop HIV-1 associated nephropathy.
Researchers were able to restore HIV genomes from serum samples more than 40 years old, enabling them to reconstruct the origins of the AIDS pandemic in unprecedented detail
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Researchers at UC San Francisco and the academically affiliated Gladstone Institutes have used a newly developed gene-editing system to find gene mutations that make human immune cells resistant to HIV infection.
The National Institutes of Health (NIH) is funding a project to investigate a personalized web app that is designed to encourage young men at risk for HIV and other sexually transmitted infections (STIs), to get routine testing. The funding for “Get Connected” is supported by the new NIH Adolescent Trials Network. As part of the UNC/Emory Center for Innovative Technology.
Scientists at the University of Basel discovered a fundamental new mechanism explaining the inadequate immune defense against chronic viral infection. These results may open up new avenues for vaccine development. They have been published in the journal “Science Immunology”.
Earlier this month, amfAR released a new report, “Curbing the HIV Epidemic by Supporting Effective Engagement in HIV Care: Recommendations for Health Plans and Health Care Purchasers,” which highlights the critical role of health plans and health care purchasers, including Medicaid and Medicare programs, marketplaces, and employers, in moving the nation toward ending the domestic HIV epidemic.
Only four in 10 gay and bisexual men in Baltimore without HIV are aware that pre-exposure prophylaxis medication (PrEP) may significantly reduce their risk of contracting the virus, even those who had recently visited a doctor or been tested for a sexually transmitted disease, new Johns Hopkins Bloomberg School of Public Health research suggests.
Cardiovascular disease has become the leading cause of death for those living with HIV, as the infection has moved from a terminal disease to a chronic illness. An article in Critical Care Nurse provides an overview of risk factors, pathophysiology and unique treatment options related to cardiovascular disease in persons living with HIV.
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