Rutgers scientists have used a diagnostic technique for the first time in the opioid addiction field that they believe has the potential to determine which opioid-addicted patients are more likely to relapse.
Associate professor Laura Wasylenki co-authored a new paper in Nature Communications that presents the results of nickel isotope analyses on Late Permian sedimentary rocks. The results demonstrate the power of nickel isotope analyses, which are relatively new, to solve long-standing problems in the geosciences.
Irvine, Calif., June 21, 2021 — A large-scale meta-analysis led by University of California, Irvine researchers provides the strongest evidence yet of which blood pressure medications help slow memory loss in older adults: those that can travel out of blood vessels and directly into the brain. The findings, published in the American Heart Association journal Hypertension, will be of interest to the 91 million Americans whose blood pressure is high enough to warrant medication, as well as the doctors who treat them.
According to researchers at Johns Hopkins Medicine, the Massachusetts Institute of Technology (MIT) and Rice University in Houston, silicone breast implants with a smoother surface design have less risk of producing inflammation and other immune system reactions than those with more roughly textured coatings. Results of the experiments using mice, rabbits and samples of human breast tissue advance knowledge of how the body responds to such implants, providing new information to physicians and affirming the benefits of certain smoother surfaces, the researchers say.
Activity of the polycomb repressive complex 1 is essential for the development and maintenance of leukemic cells; disrupting it presents a new potential therapeutic approach.
An ongoing international Alzheimer's clinical trial has found that one drug, gantenerumab, improved biomarkers of disease despite unclear cognitive effects, prompting study leaders to offer participants the option of continuing to receive the drug and participate in follow-up examinations as part of a so-called open label extension.
Researchers at Washington University School of Medicine in St. Louis have found that high levels of a normal protein associated with reduced heart disease also protect against Alzheimer’s-like damage in mice, opening up new approaches to slowing or stopping brain damage and cognitive decline in people with Alzheimer’s.
Risk of SARS-CoV-2 infection increased 30 percent for households with a recent birthday in counties with high rates of COVID-19
Findings suggest informal social gatherings such as birthday parties played role in infection spread at the height of the coronavirus pandemic
No birthday-bash infection jumps seen in areas with low rates of COVID-19
Households with children’s birthdays had greater risk of SARS-CoV-2 infection than with adult birthdays
Engineers developed inexpensive methods to make “impossible materials” that interact in unusual ways with microwave energy. Thin film polymers inkjet printed with tiny component patterns collect or transmit energy with much greater selectivity, sensitivity, and power than conventional materials.
Prior studies have investigated alternative approaches to pain reduction in burn injury patients that focus on distraction, such as music, hypnosis, toys, and virtual reality (VR). In a study published today in JAMA Network Open, Henry Xiang, MD, MPH, PhD, MBA, and his research team reported the use of smartphone-based VR games during dressing changes in pediatric patients with burn injuries.
A study from Washington University School of Medicine in St. Louis suggests that many, but not all, COVID-19 therapies made from combinations of two antibodies are effective against a wide range of virus variants, and that combination therapies appear to prevent the emergence of drug resistance.
Scientists studied the brain activity of school-aged children during development and found that regions that activated upon seeing limbs (hands, legs, etc.) subsequently activated upon seeing faces or words when the children grew older. The research, by scientists at Stanford University, Palo Alto, California, reveals new insights about vision development in the brain and could help inform prevention and treatment strategies for learning disorders. The study was funded by the National Eye Institute and is published in Nature Human Behaviour.
In a retrospective study believed to be one of the largest of its kind, researchers say they have successfully charted the health risks, growth patterns, and medical and surgical outcomes of 1,374 people with the most common form of dwarfism, called achondroplasia, seen over a 60-year period at four academic medical centers, including Johns Hopkins Medicine. The findings, according to the researchers, not only affirm some long-standing views and trends in the care of those with the condition, but also offer a standardized baseline, a blueprint investigators hope will serve to speed diagnosis and improve patients’ quality of life and health.
Lesbian, gay and bisexual people who encounter homophobic attitudes experience increases in heart rate, blood pressure and stress hormones, potentially putting them at risk for multiple health problems, according to research published by the American Psychological Association.
Instagram users who detect self-promotion or corporate marketing in a post embracing the body positivity movement may be turned off by that dual messaging, new research suggests.
University of Maryland School of Medicine (UMSOM) researchers identified a new gene that may be linked to certain neurodevelopmental disorders and intellectual disabilities.
The Threespine stickleback fish is known to have evolved independently from its marine ancestors, a process called parallel evolution. A new study details the genomic changes that drive their rapid evolution, the findings from which may shed light on the process of natural selection in other species.
• In a study of patients waiting for a kidney transplant, those who experienced various symptoms had a higher risk of dying while on the waitlist.
• Symptoms tended to increase or remain unchanged between transplant evaluation and transplantation; however, at 3 months after transplantation, 9 of 11 symptoms lessened.
• Primary nephrotic syndrome is characterized by high urinary excretion of protein, low protein in the blood, high cholesterol, and swelling in the arms and legs.
• A new analysis highlights the high risk of kidney failure and different cardiovascular complications in patients with primary nephrotic syndrome.
In Japan, thousands of homes and businesses and hundreds of lives have been lost to typhoons. But now, researchers have revealed that a new flood forecasting system could provide earlier flood warnings, giving people more time to prepare or evacuate, and potentially saving lives.
Just how do spiders walk straight up -- and even upside-down across -- so many different types of surfaces? Answering this question could open up new opportunities for creating powerful, yet reversible, bioinspired adhesives.
Researchers from Colorado State University, Amazon, and Dartmouth College published a new paper in the Journal of Marketing that examines the role of physical stores for selling "deep" products.
A research group including Professor MATSUDA Tetsuya of Tamagawa University's Brain Science Institute (Machida City, Tokyo; Director: SAKAGAMI Masamichi) and Assistant Professor ISHIHARA Toru from Kobe University's Graduate School of Human Development and Environment has illuminated the changes in the brain's neural network and cortex structure that underlie the positive association between childhood exercise and the maintenance and promotion of cognitive function in later life.
The loss of a loved one can be a defining moment, even in the animal world. In chimpanzees, for example, individuals whose mothers die when they are young are smaller than their counterparts, reproduce less and are also more likely to die at a young age.
A comprehensive health-screening program in rural northern KwaZulu-Natal, South Africa, has found a high burden of undiagnosed or poorly controlled non-communicable diseases, according to a study published in The Lancet Global Health.
A new paper in Scientific Reports led by researchers at William & Mary's Virginia Institute of Marine Science challenges increased salinity and seawater temperatures as the established explanation for a decades-long increase in the prevalence and deadliness of a major oyster disease in the coastal waters of the mid-Atlantic.
Geologic activity on Earth appears to follow a 27.5-million-year cycle, giving the planet a "pulse," according to a new study published in the journal Geoscience Frontiers.
At least so far, the currently limited research base does not establish that cannabis has additional adverse effects on brain development or functioning in adolescents or young adults with attention-deficit/hyperactivity disorder (ADHD), concludes a review in the July/August issue of Harvard Review of Psychiatry. The journal is published in the Lippincott portfolio by Wolters Kluwer.
An experimental artificial heart includes an autoregulation control mechanism, or Auto-Mode, that can adjust to the changing needs of patients treated for end-stage heart failure. Outcomes in the first series of patients managed with the new heart replacement pump in Auto-Mode are presented in the ASAIO Journal, official journal of the American Society for Artificial Internal Organs. The journal is published in the Lippincott portfolio by Wolters Kluwer.
A new study paves the way for the development of next generation therapeutics for the prevention and treatment of Clostridioides difficile infection (CDI), the most frequent cause of healthcare-acquired gastrointestinal infections and death in developed countries.
A study suggests that reducing tau protein in brain neurons will not protect against Parkinson’s disease and Lewy body dementias. If borne out, this result differs from Alzheimer’s disease, where reducing endogenous tau levels in brain neurons is protective for multiple models of the disease.
In a new study, a team of researchers uncovered new mechanisms underlying an important type of resistance to modern prostate cancer drugs called lineage plasticity, where castration-resistant prostate cancers undergo a deadly identity switch. They also outline a promising path to overcoming this form of resistance: BET bromodomain inhibitors.
Scientists at Sanford Burnham Prebys have gained a deeper insight into the intricacies of autophagy, the process in which cells degrade and recycle cellular components.
A decade-long study of distal radius fracture in older adults revealed that personalized medicine catering to a patient’s individual needs and environment, not age or X-rays, should guide treatment options. The federally funded study is the most collaborative, intense effort to try and answer a 200-year puzzle about how to treat one of the most common fractures in older adults.
An electroencephalogram (EEG) study of adolescents with autism spectrum disorder (ASD) identified a neural signal that may help explain the variation of how those with ASD perceive or understand the mental states of others (called “Theory of Mind”).
Data sharing among 40 Michigan hospitals about the care and outcomes for thousands of inpatients with COVID-19 has led to reduced variation and findings that could inform care anywhere, including approaches for preventing blood clots and reducing overuse of antibiotics, as well as a risk prediction tool.
Nearly one in three Americans between the ages of 50 and 80 put off an in-person appointment for medical care in 2020 because they were worried about exposure to the novel coronavirus, new national poll data show.
A hydrogel that forms a barrier to keep heart tissue from adhering to surrounding tissue after surgery was developed and successfully tested in rodents by a team of University of California San Diego researchers. The team of engineers, scientists and physicians also conducted a pilot study on porcine hearts, with promising results.
They describe their work in the June 18, 2021 issue of Nature Communications.
While postpartum depression in new mothers is well recognized and known to increase if the newborn requires intensive care, depression in new fathers has not received much attention. A large study, published in the journal Pediatrics, found that both parents with a baby in the NICU are at risk, with depression symptoms identified in 33 percent of mothers and 17 percent of fathers. Strikingly, the probability of reporting depression symptoms declined significantly for mothers but not for fathers after the baby came home.
DETROIT – As pandemic restrictions begin to loosen around the country and summer temperatures rise, more people will be moving about on public rideshare electric scooters. With that comes this warning: Ride with safety.A Henry Ford Health System study published in The Laryngoscope, shows that head and neck injuries caused by use of e-scooters have been on the rise since rideshare systems were introduced to the public in late 2017.
Fuel cells, part of a promising path toward zero-emission vehicles, are making progress at overcoming some specific challenges on the road to powering heavy-duty vehicles.
• Among U.S. adults with kidney failure, many of those who have the longest expected post-transplant survival are not being placed on the kidney transplant waiting list.
• African Americans, patients lacking commercial health insurance, and those residing in lower income communities are less likely to be waitlisted.
Diabetes is one of the comorbidities most strongly associated with severe COVID-19 in the US, and data from early in the pandemic suggested individuals with type 2 diabetes faced twice the risk of death from COVID-19 and a greater risk of requiring hospitalization and intensive care. A new study shows best treatment options.
In a new study using variant virus recovered from one of the original travelers, researchers in the U.S. and Japan have found that vaccination with an mRNA vaccine induces antibody responses that would protect humans from infection with the gamma/P.1 variant.