For refugee children newly arrived in the U.S., hepatitis B, tuberculosis, parasitic worms, high blood lead levels and anemia are among the top public health concerns covered by screening programs. A large epidemiological study provides health profiles of refugee children from 6 countries in Asia and Africa.
Children under age two may be at heightened risk for abuse and neglect during the six months immediately following a parent’s return from deployment in the U.S. Army, and the risk may rise among Army families with soldiers who are deployed more than once.
Newborns with a congenital heart defect often need advanced medical care to survive, leaving them vulnerable to cognitive delays. Various factors contribute to these delays. But what role does proper growth and feeding mode at the beginning of life play? A research team – led Penn Nursing – found that newborns (up to three months) with poor growth and CHD, who required device-assisted feeding, were at an increased risk for neurodevelopmental delays at six and twelve months.
A new research study from the University of Pennsylvania School of Nursing (Penn Nursing) shows that lead exposure in early childhood are associated with increased risk for sleep problems and excessive daytime sleepiness in later childhood. This is the first longitudinal, population-based study that investigated early lead exposure to sleep problems. The findings are set for publication in the December issue of SLEEP.
A simple taste test can identify patients who will have highly successful sinus surgery, researchers from Penn Medicine and the Monell Chemical Senses Center report in this week’s International Forum of Allergy & Rhinology.
New research from the Monell Center and the Perelman School of Medicine at the University of Pennsylvania suggests that physicians may someday be able to use a simple taste test to predict which surgical intervention is best suited to help a subset of chronic rhinosinusitis patients.
A new study may alleviate concerns regarding increased cancer risk for patients undergoing spinal fusion surgery with recombinant human bone morphogenetic protein (rhBMP). The study appears in November 15 issue of Spine, published by Wolters Kluwer.
Use of electronic cigarettes – or e-cigs, for short – has increased among adolescents, but the jury is still out on how many young people are becoming addicted, and how harmful they are for both young people and adults, relative to cigarettes.
Education Management Solutions (EMS), a pioneer in simulation management technology and audio-video systems for healthcare training, and Laerdal Medical, a leading provider of simulation solutions for healthcare, today announced several successful customer integrations of their respective software platforms - SIMULATIONiQ™ and LLEAP.
The Princeton Review and Entrepreneur magazine ranked the undergraduate Entrepreneurship program at Temple University’s Fox School of Business No. 8 in the country, a three-spot climb from the 2015 rankings. Fox’s graduate-level Entrepreneurship program also made the top-10. Its No. 10 ranking marked a six-spot improvement from last year.
Researchers have taken a significant step toward gene therapy for a fatal neurodegenerative disease in children. By delivering a working version of a gene to produce an enzyme lacking in Batten disease, the scientists delayed symptoms and extended lifespan in dogs with a comparable disease.
Pediatric oncology researchers have pinpointed a crucial change in a single DNA base that both predisposes children to an aggressive form of the childhood cancer neuroblastoma and makes the disease progress once tumors form. The gene change results in a "super-enhancer" that drives the cancer.
Patients with Obsessive-Compulsive Disorder (OCD) can improve their symptoms significantly by adding exposure and response prevention therapy to their treatment regimen when common drug treatment options have failed, according to new research from psychiatrists at the Perelman School of Medicine at the University of Pennsylvania. The study is published in the Journal of Clinical Psychiatry.
As the nation reels from another mass shooting on a college campus, analysis of the 2007 attack at Virginia Tech University highlights the need for "comprehensive and coordinated mental health services on college campuses, according to a paper in the November/December issue of Harvard Review of Psychiatry. The journal is published by Wolters Kluwer.
Chronic Kidney Disease (CKD), which afflicts more than 26 million Americans, is a condition in which individuals experience a slow loss of kidney function over time. At the American Heart Association Scientific Sessions 2015, researchers from the Perelman School of Medicine at the University of Pennsylvania today presented findings from their analysis of the Chronic Renal Insufficiency Cohort (CRIC) study to evaluate risk markers for adverse cardiac events in patients with CKD.
SmartTots today issued a supplement to its recent consensus statement in response to a clinical trial’s preliminary outcome that found no difference in the developing brain between two-year-olds who had undergone general anesthesia and those who had received regional anesthesia as infants.
The American Heart Association (AHA) has named Penn Nursing’s Barbara Riegel, PhD, FAHA, FAAN, professor of Nursing, the Edith Clemmer Steinbright Chair of Gerontology and director of the Biobehavioral Research Center, a 2015 Distinguished Scientist. Riegel received this honor during the opening meeting of the AHA Scientific Sessions on November 8, 2015.
Chronic Kidney Disease (CKD), which afflicts more than 26 million Americans, is a condition in which individuals experience a slow loss of kidney function over time. At the American Heart Association Scientific Sessions 2015, researchers from the Perelman School of Medicine at the University of Pennsylvania will present findings from their analysis of the Chronic Renal Insufficiently Cohort (CRIC) study to evaluate risk markers for adverse cardiac events in patients with CKD.
In an attempt to correct defects in the energy generation that contributes to poor pump function among heart failure patients, researchers examined whether the diabetes drug liraglutide, could improve the condition of patients with advanced heart failure. Despite improvements in blood sugar control, the therapy did not improve the clinical stability or pumping action of the heart in patients with advanced heart failure. Kenneth B. Margulies, MD, a professor of Medicine and research director for Heart Failure and Transplantation in the Perelman School of Medicine at the University of Pennsylvania, presented data from the Functional Impact of GLP-1 for Heart Failure Treatment (FIGHT) study at the American Heart Association Scientific Sessions 2015.
Using a video to train family members of patients at risk for cardiac arrest in CPR may be just as effective as using the traditional hands-on method with a manikin, according to new research from the Perelman School of Medicine at the University of Pennsylvania. The findings suggest simplified and more cost-effective approaches may be useful for disseminating CPR education to families of at-risk patients and the general public. The results are being presented during the American Heart Association Scientific Sessions 2015.
Providing financial incentives to both primary care physicians and patients leads to a greater reduction in low-density lipoprotein (LDL) cholesterol in patients than paying only the physician or only the patient, according to a new study led by researchers at the Perelman School of Medicine at the University of Pennsylvania. The study, which is the first to test physician-only and patient-only incentives compared to incentives shared by patients and physicians, is published in the November 10 issue of JAMA.
Mechanical CPR, in which a device is used by Emergency Medical Service (EMS) providers to deliver automated chest compressions during cardiac arrest resuscitation care, is associated with an equivalent survival rate for patients experiencing cardiac arrest outside of the hospital as manual CPR, according to new findings from a team of researchers at the Perelman School of Medicine at the University of Pennsylvania. The study is the first large scale, real-world proof that mechanical CPR may be an equivalent alternative to manual CPR for treating patients experiencing extensive cardiac arrest episodes and requiring advanced life support services. The results are being presented during the American Heart Association Scientific Sessions.
When peripheral nerves are damaged and their vital synaptic paths are disrupted, they have the ability to regenerate and reestablish lost connections. Using zebrafish, which are transparent at larval stages, the researchers identified key components that allows the nervous system to heal itself and literally obtain a whole new window into how axons regenerate.
Our chromosomes contain all of our genetic information, and it’s up to telomeres – structures of proteins that cap off and protect our DNA at the tips of chromosomes – to preserve the vital instructions necessary for life. There are even specific molecules like TERRA (Telomeric repeat-containing RNA) that exist specifically to regulate telomeres and promote chromosome end protection. Now, a new study has found that TERRA can be found outside of cells and serve as a potentially important cell signaling molecule that induces an inflammatory response, and this activity may play an important role in the development of cancer.
Training in meditation and other mindfulness-based techniques brings lasting improvements in mental health and quality of life for patients with inflammatory bowel diseases (IBD), according to a study in Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America (CCFA). The journal is published by Wolters Kluwer.
Amid continued pressures to minimize errors and cut costs, hospitals are continuing to scramble to find solutions to problems plaguing health systems nationwide. A possible solution to many of those issues can be found in hospital evidence-based practice centers (EPCs), says a new Penn Medicine study suggesting EPCs can effectively inform decision-making in medical settings.
The hippocampus, a brain structure known to play a role in memory and spatial navigation, is essential to one’s ability to recognize previously encountered events, objects, or people – a phenomenon known as recognition memory – according to new research from the departments of Neurosurgery and Psychology in the Perelman School of Medicine at the University of Pennsylvania. Their work is published in PNAS.
The Abramson Cancer Center of the University of Pennsylvania has been named the 2015 recipient of the Partners in Health Initiatives Award and Andy J. Minn, MD, PhD, assistant professor of Radiation Oncology in the Perelman School of Medicine at Penn, is the recipient of the Scientific Research Award, both presented by the Pennsylvania Division, Southeast Region of the American Cancer Society.
The gene SPOP is mutated in up to 15 percent of all cases of prostate cancer, making it one of the most mutated genes in the disease. However, when the gene is functioning properly, it acts as a tumor suppressor. Despite what’s known about SPOP, scientists have not been able to determine exactly how the gene is able to halt the progression of disease. Now, new research from The Wistar Institute has found how SPOP is able to halt tumors by inducing senescence, a state of stable cell cycle arrest, which means that the cells have stopped dividing and growing. With this new information, scientists may be able to design therapeutic strategies that can halt cancers caused by these mutated genes that are able to bypass senescence.
An international team of researchers, led by Penn State, has developed ultrasensitive gas sensors based on the infusion of boron atoms into the tightly bound matrix of carbon atoms known as graphene.
Penn Nursing to host the Philadelphia launch of a major, new report, “Women & Health: The Key for Sustainable Development,” issued by the Commission on Women & Health, a partnership between The Lancet, the Harvard T.H. Chan School of Public Health, & the University of Pennsylvania School of Nursing.
Saint Joseph’s University’s Academy of Food Marketing will host Chef Robert Irvine, star of Restaurant:Impossible, at an event to benefit the Food Marketing Educational Foundation and the Office of Veterans Services. Held on Tuesday, November 17 from 5:30 to 8 p.m. at the Fretz Kitchen Showroom located in the Philadelphia Navy Yard, the cost is $125 per person, and $75 for veterans.
Patricia D’Antonio, PhD, RN, FAAN, has been appointed director of Penn Nursing’s Barbara Bates Center for the Study of the History of Nursing. D’Antonio, the Killebrew-Censits Term Professor in Undergraduate Education and chair of the Department of Family and Community Health, previously served as the Center’s associate director. Her appointment was effective October 21, 2015.
Scientists in recent years have made great progress in characterizing the bacterial population that normally lives on human skin and contributes to health and disease. Now researchers from the Perelman School of Medicine at the University of Pennsylvania have used state-of-the-art techniques to survey the skin’s virus population, or “virome.” The study, published in the online journal mBio last month, reveals that most DNA viruses on healthy human skin are viral “dark matter” that have never been described before. The research also includes the development of a set of virome analysis tools that are now available to researchers for further investigations.
Deep brain stimulation (DBS) improves many of the motor symptoms of Parkinson’s disease (PD) and is a life-alerting surgery for many patients. Penn Medicine’s Gordon Baltuch, MD, a professor of Neurosurgery and director of the Penn Center for Functional and Restorative Neurosurgery, is one of the most prolific DBS surgeons in the world, having recently performed his 1,000th procedure, marking an important milestone for Baltuch and Penn Medicine.
Regular physical activity could play a role in helping women at high-risk of breast cancer delay the need for drastic preventive measures such as prophylactic mastectomy, according to new research led by the Perelman School of Medicine at the University of Pennsylvania. Results of the WISER Sister study help clarify the emerging connection between exercise and breast cancer risk. As a result of the new findings, the authors suggest that women who have an elevated breast cancer risk or worry about having such risk should consider doing 30 to 60 minutes of aerobic activity per day for five days per week.
One virus creates a long-lived immune reaction in parts of our bodies that serve as our first line of defense against infections, making it a strong candidate for a variety of vaccines.
After peaking in 2007, AIDS mortality in South Africa has decreased with the widespread introduction of effective antiretroviral therapy, according to updated estimates published in AIDS, official journal of the International AIDS Society. AIDS is published by Wolters Kluwer.
Abdominoplasty—sometimes called "tummy tuck"—has a higher risk of major complications than other cosmetic plastic surgery procedures, reports a study in the November issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
For patients undergoing plastic surgery procedures, there's no consistent evidence that taking antidepressants increases the risk of bleeding, breast cancer, or other adverse outcomes, concludes a research review in the November issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
When facing a cancer diagnosis, it can be challenging to keep one’s spirits up. For women, the side effects that treatment may have on their physical appearance can make it difficult to leave the house and face the world.
Autophagy, the degradation of unwanted cellular bits and pieces by the cell itself, has been shown for the first time to also work in the cell nucleus. In this setting it plays a role in guarding against the start of cancer.
Patients who are divorced, separated or widowed had an approximately 40 percent greater chance of dying or developing a new functional disability in the first two years following cardiac surgery than their married peers, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania published in this week’s JAMA Surgery.
Researchers from around the world are working to improve soldiers' health and physical performance and health—with the goal of increasing military readiness and effectiveness, according to the November special issue of The Journal of Strength and Conditioning Research, official research journal of the National Strength and Conditioning Association (NSCA). The journal is published by Wolters Kluwer.
Pediatric researchers have developed the first set of growth charts for U.S. children with Down syndrome since 1988. These new charts provide an important tool for pediatricians to evaluate growth milestones for children and adolescents with this condition.