Curated News: PLOS

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11-Jan-2018 12:05 PM EST
Researchers Offer New Model for Uncovering True HIV Mortality Rates in Zambia
Lombardi Comprehensive Cancer Center at Georgetown University

A new study that seeks to better ascertain HIV mortality rates in Zambia could provide a model for improved national and regional surveillance approaches, and ultimately, more effective HIV treatment strategies.

Released: 10-Jan-2018 11:05 AM EST
New Study Shows High Cost of Screening for, Diagnosis and Treatment of Non-Communicable Diseases in Kenya
RTI International

Non-communicable diseases — such as cancer, cardiovascular disease, respiratory disease and diabetes — are responsible for more than 36 million deaths across the globe each year. 14 million of these constitute premature mortality, and 90 percent of these premature deaths take place in low- and middle-income countries.

5-Jan-2018 9:00 AM EST
Climate Change Drives Collapse in Marine Food Webs
University of Adelaide

A new study has found that levels of commercial fish stocks could be harmed as rising sea temperatures affect their source of food.

3-Jan-2018 10:05 AM EST
DNA Analysis of Ancient Mummy, Thought to Have Smallpox, Points to Hepatitis B Infection Instead
McMaster University

Scientists have sequenced the complete genome of an ancient strain of Hepatitis B, shedding new light on a pathogen that today kills nearly one million people every year. The findings, based on data extracted from the mummified remains of a small child buried in Naples, Italy, confirm the idea that HBV has existed in humans for centuries.

   
22-Dec-2017 4:35 PM EST
Gene Therapy Using CAR T-Cells Could Provide Long-Term Protection Against HIV
University of California, Los Angeles (UCLA), Health Sciences

Through gene therapy, researchers engineered blood-forming stem cells (hematopoietic stem/progenitor cells, or HSPCs) to carry chimeric antigen receptor (CAR) genes to make cells that can detect and destroy HIV-infected cells. These engineered cells persisted for more than two years

26-Dec-2017 2:05 PM EST
Want to Beat Antibiotic-Resistant Superbugs? Rethink That Strep Throat Remedy
Georgia Institute of Technology

Antibiotics could become nearly useless by mid-century against intense infections due to bacteria evolving antibiotic resistance. And alternatives haven't been able to replace them. It's time for a rethink: Try reducing antibiotic use for small infections and find alternate treatments for them. Save antibiotics for the big infections.

Released: 21-Dec-2017 4:05 PM EST
Selective Suppression of Inflammation Could Deplete HIV and Control HIV Activation
Case Western Reserve University

A class of anti-inflammatory drugs already FDA-approved for rheumatoid arthritis could “purge” the reservoir of infected immune cells in people infected by HIV, according to new research.

Released: 20-Dec-2017 6:00 AM EST
Aggression in Childhood: Rooted in Genetics, Influenced by the Environment
Universite de Montreal

According to a new psychosocial study, reactive and proactive types of aggressive behaviour in 6-year-old children share most of the same genetic factors. However, their evolution over time seems to be influenced by various environmental factors, suggesting the need to develop different intervention methods.

   
Released: 18-Dec-2017 5:05 AM EST
‘Brain-on-a-Chip” to Test Effects of Biological & Chemical Agents, Develop Countermeasures
Lawrence Livermore National Laboratory

Lawrence Livermore National Laboratory scientists and engineers have developed a “brain-on-a-chip” device that could be used to test and predict the effects of biological and chemical agents, disease, or pharmaceutical drugs on the brain over time without the need for human or animal subjects.

Released: 13-Dec-2017 2:00 PM EST
Genomic Blood Test Predicts Survival Rates After Surgery for Advanced Heart Failure
University of California, Los Angeles (UCLA), Health Sciences

An experimental blood test developed at UCLA that uses gene activity data from immune cells was 93 percent accurate in predicting survival rates for people with advanced heart failure who had surgery to implant mechanical circulatory support devices.

11-Dec-2017 1:05 PM EST
Monkey Study Shows a Path to Monitoring Endangered Species
University of Wisconsin–Madison

A Brazilian-American research group has just published an unusual study outlining data needs for monitoring the survival of monkeys called muriquis that live in patches of forest in Brazil.

13-Dec-2017 2:00 PM EST
New Study Finds Lyme Bacteria Survive a 28-day Course of Antibiotics When Treated Four Months After Infection by Tick Bite
Tulane University

Lyme bacteria can survive a 28-day course of antibiotic treatment four months following infection by tick bite, according to a new study using a primate model for the disease. Despite testing negative for Lyme disease, some subjects were infected with Lyme bacteria in heart, brain and other organs.

Released: 11-Dec-2017 4:05 PM EST
Kyra’s Legacy
Perelman School of Medicine at the University of Pennsylvania

Pets have become an integral part of human medical research. However, a recent collaboration between Penn Med and Penn Vet has turned the tables on the arrangement.

29-Nov-2017 5:05 PM EST
“Obesity Paradox” Not Found When Measuring New Cases of Cardiovascular Disease
New York University

A new study by NYU College of Global Public Health and the University of Michigan finds that the “obesity paradox” is not present among people with new cases of cardiovascular disease.

Released: 6-Dec-2017 8:05 PM EST
NUS Researchers Uncover Novel Pathway to Suppress Virus-Induced Cancers
National University of Singapore (NUS)

Researchers at the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) have identified a novel molecular pathway by which a tumour suppressor, TIP60, inhibits the growth of cancer cells.

Released: 6-Dec-2017 5:05 PM EST
UAH Professors Find “Widespread Misattribution” in Research Publications and Grant Proposals
University of Alabama Huntsville

UAH business professors find a pattern of widespread misattribution in publications and in research proposals with significant variation by academic rank, discipline, sex, publication history, co-authors, and other factors.

Released: 6-Dec-2017 2:05 PM EST
Link Found Between Estrogens and Changes in Heart Physiology
University of Alabama at Birmingham

Using zebrafish mutants in four different estrogen receptors, Daniel Gorelick has found a novel mechanism of estrogen action on heart physiology. Broader use of the mutants, he says, may have significant implications for studies of estrogenic environmental endocrine disruptors.

6-Dec-2017 10:05 AM EST
Some Video Games Are Good for Older Adults' Brains
Universite de Montreal

Summary: Playing 3D-platform video games on a regular basis may improve cognitive functions in seniors and increase grey matter in a brain structure called the hippocampus, a Canadian study suggests

Released: 5-Dec-2017 10:05 AM EST
Scientists Find Potential Weapons for the Battle Against Antibiotic Resistance
University of North Carolina Health Care System

This UNC research shows how understanding the precise mix of bacteria and their interactions could become a standard part of clinical practice in treating bacterial infections, especially the more dangerous infections involving antibiotic resistance.

Released: 28-Nov-2017 2:30 PM EST
New Computer Model Sheds Light on Biological Events Leading to Sudden Cardiac Death
 Johns Hopkins University

a powerful new computer model replicates the biological activity within the heart that precedes sudden cardiac death.



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