Feature Channels: Diabetes

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Johns Hopkins Medicine researchers say mysterious, previously unseen “X cell” may be cause of type 1 diabetes

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Pediatricians are often reluctant to recommend bariatric surgery for teen-agers, but a Rutgers-led study concludes it is a justifiable treatment for adolescents with persistent extreme obesity if they can maintain a healthy lifestyle afterward.

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Johns Hopkins Medicine researchers created an online patient community for women living with all types of diabetes to test whether online communities can engage patients and provide information that can guide research and patient care. The researchers found that the majority of women who joined the online community used it at least occasionally to ask or respond to questions and ideas about research as well as patient care.

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Children with type 1 diabetes find it difficult to adhere to their drug routines during school holidays and weekends. Holiday distractions cause a 20% reduction in adherence to taking medications that assist managing their condition and other associated conditions, which may have serious consequences for their health.

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Research findings opens opportunities to offer opportunities to develop new treatments to tackle metabolic diseases, like diabetes.

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An international consortium of scientists has analyzed protein-coding genes from nearly 46,000 people, linking rare DNA alterations to type 2 diabetes.

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Sheila Blumberg, MD, a vascular surgeon at NYU Langone Hospital–Brooklyn, used advanced surgical techniques to save the foot of Brooklyn native Jose Palacios.

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SR9009 is a compound that can lead to a wide range of health benefits in animals, including reduced risk of obesity and type 2 diabetes. Until now, researchers have attributed the effects to SR9009’s role in altering the body’s circadian clock. However, in a first-of-its-kind study from Penn Medicine, published today in PNAS, researchers found that SR9009 can effect cell growth and metabolic function without the involvement of REV-ERBs.

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BOSTON -- (May 13, 2019) -- A new study from Joslin Diabetes Center has proven that certain biological protective factors play a large role in preventing diabetic kidney disease in certain people. The study was published today in Diabetes Care. This study built on the findings from a 2017 Joslin Medalist Study of protective factors and diabetic kidney disease (or DKD).

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Over one-third of all FDA-approved drugs act on a specific family of proteins: G-protein coupled receptors (GPCRs). Drugs to treat high blood pressure, asthma, cancer, diabetes and myriad other conditions target GPCRs throughout the body—but a recent study shows what happens next. In results published in Cell, researchers outline the timeline of events, including precisely when and how different parts of a GPCR interacts with its G protein signaling partners. The findings provide new insights into the fundamental mechanisms of drug-induced signaling in cells, including ways to identify the most critical portions of GPCRs for targeting development of novel therapeutics.

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A new discovery made mainly in mice could provide new options for getting the insulin-making "factories" of the pancreas going again when diabetes and obesity have slowed them down. It could offer new pathways to ramping up insulin supply to get metabolism back on track in people with Type 1 and Type 2 diabetes, and obesity.

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Current treatments of Type 2 diabetes can help the body use insulin at various stages of the disease, but they can also be expensive and subject patients to lifelong medication regimens and side effects. Thanks to new therapeutic ultrasound technology, one promising alternative looks to reshape how early Type 2 diabetes is managed. A group of researchers has used ultrasound therapy to stimulate insulin release from mice on demand. The team will present their findings at the 177th ASA Meeting, May 13-17.

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One year after Philadelphia passed its beverage tax, sales of sugary and artificially sweetened beverages dropped by 38 percent percent in chain food retailers, according to Penn Medicine researchers who conducted one of the largest studies examining the impacts of a beverage tax. The results, published this week in JAMA, translate to almost one billion fewer ounces of sugary or artificially sweetened beverages – about 83 million cans of soda – purchased in the Philadelphia area. The findings provide more evidence to suggest beverage taxes can help reduce consumption of sugary drinks, which are linked to the rise in obesity and its related non-communicable diseases, such as type II diabetes.

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*For the first time, researchers have developed a non-intrusive way to generate large quantities of stem cells using only a small amount of blood* *The stem cells can repair cells damaged as a result of vascular diseases, which has the potential to prevent blindness and reverse the need for amputations*

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Twenty-three year old Lauren Williams was rushed to Danbury Hospital with diabetic ketoacidosis (DKA), a serious complication of Type 1 diabetes. Danbury Hospital emergency, progressive care, and endocrinology care teams are highly skilled at effectively and expeditiously identifying and treating DKA

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Researchers at Joslin have found that increasing the proliferation and turnover of beta cells before signs of type 1 diabetes could halt the development of the disease.

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BOSTON – (April 29, 2019) – Newly available results will influence the standard approach for treating diabetic macular edema in patients with good vision, thanks to a study published today in the Journal of the American Medical Association. The study was conducted by the DRCR Retina Network, a multicenter clinical research network funded by the National Eye Institute, part of the National Institutes of Health (NIH).

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As if people living with diabetes didn’t have enough health concerns, here’s another: increased risk of metastatic cancer. New Cornell University research points to a possible explanation for this health double whammy.

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Patients with diabetes and low blood glucose have higher rates of death following hospital discharge, according to a study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.

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A diabetes drug is being enlisted in the war against smoking by UTHealth researchers.