Feature Channels: Diabetes

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Case Western Reserve University School of Medicine has received a three-year, $1,118,556 grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health to investigate a new imaging approach for diagnosing peripheral arterial disease, a common and potentially serious circulatory problem. More than 200 million people worldwide suffer from the condition.

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Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) have found that the anti-malaria drug amodiaquine inhibits the apelin receptor protein, which helps drive the vascularization behind diabetic retinopathy, wet age-related macular degeneration (AMD) and other conditions. Because the drug has been approved to treat malaria for decades, it could move relatively quickly through the pipeline to help patients. The study was published in the journal PLOS ONE.

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As the U.S. Eastern seaboard braces for Hurricane Florence, a category 4 hurricane that could potentially impact several states including Georgia, South Carolina, North Carolina and Virginia between Thursday and Friday, the diabetes community is rallying to make sure that people living with diabetes—especially those who depend upon insulin—are fully supported. The Diabetes Disaster Response Coalition (DDRC), which is comprised of the Endocrine Society and other leading diabetes organizations, is urging all people with diabetes and their loved ones to prepare for Hurricane Florence by putting together a diabetes kit and making a plan to stay healthy and safe during the storm and in its aftermath.

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Researchers at University of Utah Health examined the diabetes community’s online Twitter conversation to understand their thoughts concerning open source artificial pancreas (OpenAPS) technology.

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Obesity and its related ailments like type 2 diabetes and fatty liver disease pose a major global health burden, but researchers report in Nature Communications that blocking an RNA-silencing protein in the livers of mice keeps the animals from getting fat and diabetic conditions.

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The National Institutes of Health (NIH) has awarded New York University nearly $66 million over the next five years to study how exposure to environmental factors influences children’s health. This new funding is an extension of a previous award of nearly $15 million over the last two years from an NIH initiative called Environmental influences on Child Health Outcomes (ECHO), which investigates how a range of environmental factors in early development – from conception through early childhood – affects the health and development of children and adolescents.

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Progress in treating chronic illness, where the cause of the problem is often unknown, has lagged. Chronic conditions like cancer, diabetes and cardiovascular disease defy easy explanation, let alone remedy. In a new paper, a researcher at University of California San Diego School of Medicine, posits that chronic disease is essentially the consequence of the natural healing cycle becoming blocked, specifically by disruptions at the metabolic and cellular levels.

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A new “virtual” drug development startup company, Enspire Bio, will channel the knowledge and financial resources necessary to translate basic science — the bedrock of medicine — into powerful treatments. And, in a notable departure from traditional approaches, the translation will occur in the heart of the research lab.

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Losing a single night’s sleep may affect the liver’s ability to produce glucose and process insulin, increasing the risk of metabolic diseases such as hepatic steatosis (fatty liver) and type 2 diabetes. The findings of the mouse study are published ahead of print in the American Journal of Physiology—Endocrinology and Metabolism. The research was chosen as an APSselect article for September.

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Surgical site infections are a significant complication that can prevent proper wound healing, require expensive treatment and may even lead to death in severe cases. Patients with higher body mass indices and with diabetes have an increased risk of developing incision infections.With a $1.7 million, two-year grant from the Centers for Disease Control and Prevention, researchers in the University of Illinois at Chicago Epicenter for Prevention of Healthcare Associated Infections — one of six such centers funded by the CDC — will determine whether negative pressure wound therapy can help reduce the incidents of surgical site infections in obese and diabetic patients.

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Physician researchers with The Ohio State University College of Medicine at the Wexner Medical Center say increased levels of the hormone aldosterone, already associated with hypertension, can play a significant role in the development of diabetes, particularly among certain racial groups.

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The latest research, features and announcements in healthcare in the Healthcare News Source

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The role of insulin as a boost to the immune system to improve its ability to fight infection has been detailed for the first time by Toronto General Hospital Research Institute (TGHRI) scientists.

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Immune reactions are usually a good thing--the body's way of eliminating harmful bacteria and other pathogens.

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Cedars-Sinai investigators have developed a simpler and more accurate method of estimating body fat than the widely used body mass index, or BMI, with the goal of better understanding obesity. The new method is highlighted in a study published in Scientific Reports, one of the Nature journals.

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As the Hawaiian Islands brace for Hurricane Lane, a category 4 hurricane that could potentially impact Hawaii between Thursday and Friday, the diabetes community is rallying to make sure that people living with diabetes that use insulin are taking special precautions. The Diabetes Disaster Response Coalition (DDRC) which is comprised of the Endocrine Society and several other leading diabetes organizations is urging all people with diabetes and their caregivers in Hawaii to act now to prepare for Hurricane Lane by putting together a diabetes kit and making a plan to stay healthy and safe during the storm and in its aftermath.

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AADE awarded $2.6 million grant over three years by The Leona M. and Harry B. Helmsley Charitable Trust for its new DANA resource.

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Probiotics seem to be everywhere these days – in yogurt, pickles, bread, even dog food. But there’s one place that may surprise you: There are probiotics in dirty diapers.

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A Mayo Clinic foi eleita o melhor hospital do país na 29ª lista de honra dos melhores hospitais dos EUA do periódico U.S. News & World Report. A Mayo Clinic também ficou em primeiro lugar em mais especialidades do que qualquer outro hospital dos EUA.