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Released: 16-Sep-1997 12:00 AM EDT
ATS Journal News Tips, September
American Thoracic Society (ATS)

The following stories appear in the American Thoracic Society (ATS) September journals: 1) Hospitalization claims more than half of the health care dollar spent on asthmatics; 2) Deaths from lung diseases growing faster in females; 3) Researchers find marker to identify patients with acute lung injury in early stages of disease progression

Released: 16-Sep-1997 12:00 AM EDT
Antirejection Antibody Could End Lifelong Use of Immunosuppressants
Research Corporation Technologies

Ongoing preclinical studies of an antirejection antibody have established its ability to prevent and reverse organ rejection while leaving the immune system intact.

Released: 16-Sep-1997 12:00 AM EDT
Health, Labor Groups Applaud 'Careful' Clinton Review of Tobacco Deal, Urge 'Full Document Disclosure'
American Lung Association (ALA)

More than 290 public health, labor and other grassroots groups from around the nation today urged President Clinton to require "full document disclosure" from the tobacco industry before endorsing any deal with the cigarette companies.

16-Sep-1997 12:00 AM EDT
Excessive Antibiotic Prescribing for Viral Respiratory Illnesses Could Explain Some Drug Resistance
University of Colorado Anschutz Medical Campus

Physicians frequently prescribe antibiotics for common viral respiratory illnesses that typically do not benefit from antibiotic therapy, according to an article in tomorrow's issue of The Journal of the American Medical Association. The study, co-authored by Ralph Gonzales, MD, MSPH, assistant professor of medicine, University of Colorado Health Sciences Center, could offer insight into the rapidly rising prevalence of antibiotic-resistant bacteria.

Released: 15-Sep-1997 12:00 AM EDT
Study shows for the first time the major predictor of resistence to AIDS drugs
Albany Medical Center

Albany Medical College researchers have for the first time provided data that shows that the major predictor of resistance to AIDS drugs is whether the amount of virus in a patient's body has been reduced to nondetectable limits. The analysis showed that among the patients who received just Indinavir, those who were able to reduce the amount of virus in them to less than detectable levels had "significantly lower risks of emergence of resistance" to the drug. When combination therapy was used, such as a combined treatment of Indinavir, AZT, and 3TC, patients had significantly longer times to resistance compared to monotherapy patients even after adjusting statistically for the increased antiviral effect of the additional drugs.

13-Sep-1997 12:00 AM EDT
Sythetic Steroid Dramatically Reduces Stroke Damage; Heralds New Class Of Drugs
Boston University

A research team at Boston University School of Medicine has discovered that a synthetic compound significantly limits brain damage when administered after a stroke. Their finding, published September 16 in the Proceedings of the National Academy of Sciences, could lead to the development of drugs to treat stroke and traumatic brain or spinal cord injury. These new drugs could also slow the progression of Parkinsonís disease and ALS, more commonly known as ìLou Gehrigís disease.î

12-Sep-1997 12:00 AM EDT
Artificial intelligence improves heart attack diagnosis
American Heart Association (AHA)

Drawing on artificial intelligence technology, researchers have for the first time found that machines show promise of improving on human's ability to diagnose heart attacks, according to a study in today's American Heart Association journal Circulation.

   
12-Sep-1997 12:00 AM EDT
Studies link calcium problem to atherosclerosis and osteoporosis
American Heart Association (AHA)

Two diseases -- atherosclerosis and osteoporosis -- may be linked by a common problem in how the body uses calcium, according to two reports in American Heart Associations journals. One report is published in Stroke, the other is in today's Circulation.

12-Sep-1997 12:00 AM EDT
Gene mutant leads to five-fold heart attack risk
American Heart Association (AHA)

Researchers have found a mutation in a fat-dissolving gene that raises the risk of heart attack by five-fold compared to individuals with a normal gene. Reporting in today's American Heart Association journal Circulation, they say the gene mutation may place 1 in 1,500 individuals at increased risk for heart attack.

12-Sep-1997 12:00 AM EDT
Digital Holography Helps Plastic Surgeons Reshape Abnormal Skulls of Children
Communications Plus

Dr. David Furnas, Chief of the Department of Plastic Surgery at the University of California-Irvine Medical Center, will report tomorrow how the Digital Holographyô System from Voxelô (NASDAQ:VOXL) is helping plastic surgeons reshape congenitally malformed skulls. The holograms produced by the system have helped clinicians diagnose craniofacial problems, create pre-surgical plans, and intraoperatively measure and reconstruct these misshapened skulls.

11-Sep-1997 12:00 AM EDT
Hyperbaric Oxygen Doesn't Speed Healing
Temple University Health System

Results from a Temple University Hospital study indicate that hyperbaric oxygen (HBO) therapy does not speed healing time for soft-tissue sports injuries. Although HBO therapy is becoming increasingly popular with professional sports teams, this study marks the first time it has been put to the scientific test.

16-Sep-1997 12:00 AM EDT
Annals of Internal Medicine TipSheet for 9-15-97
American College of Physicians (ACP)

1) Nonsteroidal anti-inflammatory drugs are often prescribed unnecessarily for the elderly, and complications from such drugs are misdiagnosed or mismanaged by doctors; 2) Screening tests reliably detect deep venous thrombosis and pulmonary embolism after total hip or knee arthroplasty; 3) The Federated Council of Internal Medicine releases guidelines for internal medicine residency education; 4) Treating asthma with antilukotrienes, a new class of drugs.

12-Sep-1997 12:00 AM EDT
First Images of Key Viral Protein Could Lead to New Strategies for Human Gene Therapy
Whitehead Institute for Biomedical Research

New images of an L-shaped molecule on the surface of a mouse leukemia virus could help scientists realize the promise of human gene therapyãthe effort to cure disease by inserting genes directly into human cells. The images, published in the September 12 issue of Science, show the crystal structure of a piece of the virusπs envelope proteinãthe piece required to recognize and bind to receptors on the surface of a mammalian cell.

Released: 13-Sep-1997 12:00 AM EDT
Neurologists learn magnetic brain stimulation
University of Maryland, Baltimore

At a World Congress of Neurology in Buenos Aires the week of September 14-19, neurologists from around the world will learn a new noninvasive technique for study and diagnosis of brain diseases. Neurology professors from the University of Maryland School of Medicine in Baltimore, Maryland, and from Rome, Italy will teach magnetic brain stimulation.

Released: 13-Sep-1997 12:00 AM EDT
Study Launched to Test Selective Serotonin Reuptake Inhibitor in Children Suffering from Anxiety Disorders
NewYork-Presbyterian Hospital/Columbia University Medical Center

Nearly 12 million children and adolescents are diagnosed with emotional disorders, including anxiety and depression, in the United States each year. Yet because the medications used to treat these disorders are tested mainly on adults, little is known about their safety and efficacy in children and adolescents. Now, a new National Institutes of Health research center at Columbia University's College of Physicians & Surgeons aims to correct that deficit.

Released: 12-Sep-1997 12:00 AM EDT
New Oral Insulin Delivery System Shows Promise
Purdue University

Researchers at Purdue University have developed an oral delivery method for insulin that may eliminate a diabetic's need to take insulin injections.

Released: 12-Sep-1997 12:00 AM EDT
Emergency Physicians Convention in San Francisco: Focus on Clinical and Technological Innovations, the Future of Emergency Medicine, and Managed Care
American College of Emergency Physicians (ACEP)

The American College of Emergency Physicians, a medical specialty association of more than 19,000 members, will hold its premier annual conventionóScientific Assemblyófrom Thursday, October 16, until Sunday, October 19, in San Francisco, California. As the world's most comprehensive forum for emergency medicine education, the convention will consist of 4 days of curriculum with more than 240 presentations, more than 500 exhibits, and a Research Forum that will present poster and oral presentations of original emergency medicine research.

Released: 12-Sep-1997 12:00 AM EDT
Vital Statistics Report Shows Significant Gains In Health
National Center for Health Statistics (NCHS, CDC)

Broad gains in the nation's health, including a dramatic decline in the AIDS death rate as well as continued decline in the teen birth rate, was reported today by HHS' Centers for Disease control and prevention.

Released: 12-Sep-1997 12:00 AM EDT
Hopkins Researchers Study Space Flight's Effects on Blood Vessels
Johns Hopkins Medicine

Are astronauts at risk of developing coronary artery disease from spending time in space, or can their blood vessels adapt to the change in gravity? To find out, Johns Hopkins researchers are preparing a cargo of special cells to board the shuttle Atlantis for a 10-day trip including a stop at space station Mir. The shuttle is scheduled to launch from Cape Canaveral, Fla., on Sept. 25.

   
Released: 12-Sep-1997 12:00 AM EDT
Study Casts Doubt on Effectiveness of TB Vaccine
Stanford Medicine

The tuberculosis vaccine known as BCG has been given to more people worldwide than any other vaccine, yet its effectiveness remains controversial. A new analysis by researchers at Stanford School of Medicine suggests that the bacterial strains used in current BCG vaccines have evolved in the laboratory and are now considerably weaker -- and less likely to provide protection from tuberculosis -- than the original vaccine developed about 75 years ago in France.

Released: 12-Sep-1997 12:00 AM EDT
Intercourse Not a Risk Factor for Premature Labor
University of Illinois Chicago

Some expectant parents fear that intercourse during pregnancy may cause premature labor. But a study by researchers at the University of Illinois at Chicago College of Medicine found that there is no direct and clear link between sexual intercourse and spontaneous labor.

12-Sep-1997 12:00 AM EDT
Better Maternal Nurturing Mean Better Physical and Physiologic Response to Stress for Adult Rats, Reported in Science
Emory University Woodruff Health Sciences Center

The more newborn rat pups are licked and groomed by their mothers, the better equipped they are to handle acute stress in adulthood, report Emory University's Paul M. Plotsky, PhD, and his McGill University colleagues in the week's issue of Science.

Released: 11-Sep-1997 12:00 AM EDT
New Research Confirms Green Tea Supplement Provides Best Antioxidant Protection
Pharmanex

Researchers at the University of Kansas have found new evidence confirming that a compound in a green tea supplement provides stronger damage protection of cells and their genetic material (DNA) than the well-known antioxidants vitamins E and C and the antioxidant compound in red wine. Announced today at the American Chemical Society annual meeting, the first side-by-side comparative antioxidant study led to an investigation of the protective power of epigallocatechin gallate (EGCG) against that of vitamins E and C, in addition to red wine and other teas.

11-Sep-1997 12:00 AM EDT
Study Finds Osteoporosis Drug Prevents Additional Fractures in the Spine
Fleishman-Hillard, New York

Women with established osteoporosis who have already experienced a vertebral fracture may be able to reduce their risk of additional fractures in the spine by taking calcitonin-salmon, a currently available medication delivered via nasal spray, according to a new study presented this week at the annual scientific meeting of the American Society for Bone and Mineral Research (ASBMR).

Released: 11-Sep-1997 12:00 AM EDT
Mayo Clinic Women's HealthSource Reports--September Issue
Mayo Clinic

1) How to control heartburn; 2) Many solutions are available for stress urinary incontinence; 3) Later-age pregnancy means greater risks and greater benefits.

9-Sep-1997 12:00 AM EDT
More Proof that Green Tea may Postpone Cancer, Heart Disease
University of Kansas

An antioxidant found in green tea is at least 100 times more effective than vitamin C and 25 times better than vitamin E at protecting cells and their genetic material, DNA, from damage believed to be linked to cancer, heart disease and other potentially life-threatening illnesses, University of Kansas research shows.The antioxidant, known as epigallocatechin gallate, or EGCG, carries twice the antioxidant punch of resveratrol, found in red wine, according to the study.

Released: 10-Sep-1997 12:00 AM EDT
Permanent Implants for Prostate Cancer, Radiation Therapy
American College of Radiology (ACR)

Studies covering topics ranging from the quality of life after permanent prostate implants to using radiation therapy to treat soft tissue sarcomas in children will be presented at the American Society for Therapeutic Radiology and Oncology. The meeting will be held in Orlando, FL October 19-23 at the Orange County Convention Center.

Released: 9-Sep-1997 12:00 AM EDT
Causes of Heart Disease a Mystery to Many
University of Illinois Chicago

Many patients with heart ailments do not recognize smoking, high blood pressure or high cholesterol levels as risk factors for their own condition, according to a study by researchers at the University of Illinois at Chicago and two other institutions.

Released: 9-Sep-1997 12:00 AM EDT
Anti-Cancer Tablet Tested at UIC Institute
University of Illinois Chicago

As the University of Illinois at Chicago's Institute for Tuberculosis Research celebrates its 50th anniversary, researchers here are moving forward to identify components of the tuberculosis vaccine, BCG, that are effective in the treatment of cancers when taken orally.

Released: 9-Sep-1997 12:00 AM EDT
UIC Study Finds Sleep Apnea Problems in African-American Children
University of Illinois Chicago

African-American children with obstructive sleep apnea have significantly lower blood-oxygen levels compared to other groups, according to a study by sleep disorder researchers at the University of Illinois at Chicago College of Medicine.

5-Sep-1997 12:00 AM EDT
Evidence Of Tobacco Carcinogen In Non-Smokers Passively Exposed To Cigarette Smoke
American Chemical Society (ACS)

New research shows, for the first time under real-life conditions, evidence of a cancer-causing substance in non-smokers who work in smoke-filled rooms. That substance, called NNK, was biologically processed and its metabolite detected in their urine. The study is being presented here today at a national meeting of the American Chemical Society. Embargoed for 9-9-97, 4:30 PM EDT

27-Aug-1997 12:00 AM EDT
Strict blood pressure control needed to stall kidney disease progression in African-Americans
American Heart Association (AHA)

African-Americans may need to become even stricter in controlling blood pressure if they hope to fight kidney disease, warn researchers today in the American Heart Association journal Hypertension.

Released: 8-Sep-1997 12:00 AM EDT
Paracel

Paracel Inc. today announced a new class of scientific computing for drug discovery that accelerates the analysis of genes that cause disease by as much as 1,000 times over traditional computing alternatives. The GeneMatcherô computer system will be introduced at the Ninth Genome Sequencing and Analysis Conference, Hilton Head, S.C., Sept. 13-16. Embargoed: Sept. 13

   
5-Sep-1997 12:00 AM EDT
Enzymes,Ethnicity Create Dramatic Differences In Codeine's Effectiveness In Humans
American Chemical Society (ACS)

The pain-relieving drug codeine is totally ineffective in some ethnic groups -- including one in ten whites -- according to new findings presented here today at a national meeting of the American Chemical Society. The report shows a variety of differences in the drug's effectiveness and side effects, based on a person's ethnicity. Embargoed for 9-8-97, 7:00 PM EDT

5-Sep-1997 12:00 AM EDT
Move Over, Red Wine: Peanuts Contain Heart-Healthy Compounds
American Chemical Society (ACS)

You've heard that small doses of red wine may be good for your health. Now, United States Department of Agriculture scientists say that peanuts may contain the heart- healthy chemical compound --resveratrol -- important in red wine. The latest findings that edible peanuts also contain resveratrol were presented here today at a national meeting of the American Chemical Society. Embargoed for 9-8-97, 11PM EDT

27-Aug-1997 12:00 AM EDT
Dental health, chronic infections double brain attack risk
American Heart Association (AHA)

Dental infections and other chronic infections such as bronchitis more than double the risk of having a stroke or "brain attack," according to a study by German researchers reported in today's American Heart Association journal Stroke.

Released: 5-Sep-1997 12:00 AM EDT
Pawpaw Shows Promise In Fighting Drug-Resistant Tumors
Purdue University

A Purdue University researcher has found compounds in the bark of the pawpaw tree that have shown some success in fighting drug-resistant cancers. Details will be presented Thursday, Sept. 11 at the American Chemical Society national meeting in Las Vegas.

5-Sep-1997 12:00 AM EDT
Discovery of Genetic Pathways May Provide New Ways to Combat Candida Infections
Whitehead Institute for Biomedical Research

A new study has uncovered the genetic wiring diagram underlying the infectiousness of Candida albicans, a fungus that causes thrush in babies, vaginal infections in women, and life-threatening infections in chemotherapy and AIDS patients. The study, led by Dr. Gerald R. Fink, Director of the Whitehead Institute for Biomedical Research, reveals that one key to Candidaís infectiousness lies in its ability to switch from a rounded form to filamentous forms. When the wiring diagram underlying this switch is inactivated, Candida infections are no longer deadly in mice.

Released: 4-Sep-1997 12:00 AM EDT
Gene Found for Crippling Neurologic Disorder
Mount Sinai Health System

A research team led by investigators from the Massachusetts General Hospital (MGH) has identified and cloned the gene responsible for early-onset dystonia, a crippling, inherited neurological disorder that begins in childhood. The discovery, announced in the September issue of Nature Genetics, is the culmination of more than 15 years of work and contains important clues that could lead to better understanding of the disease and possible preventive treatments.

Released: 4-Sep-1997 12:00 AM EDT
Heart problems in victims of tropical disease may not be caused by autoimmune rejection; new treatment indicated
University of Georgia

New evidence by scientists from the University of Georgia indicates that victims of a common tropical disease may be receiving inadequate treatment because of a major misunderstanding of how the illness progresses.

Released: 4-Sep-1997 12:00 AM EDT
Doctors Take Antioxidant Vitamins
Council for Responsible Nutrition (CRN)

More doctors take antioxidant supplements than take aspirin as a way to prevent heart attacks according to a study published in the June American Journal of Cardiology. While numerous studies have shown aspirin to be highly effective in preventing heart disease, 42 percent of cardiologists interviewed take aspirin and 44 percent take vitamin E, vitamin C, or beta carotene, alone or in combination.

Released: 4-Sep-1997 12:00 AM EDT
New Study Shows Personalized Program Increases Smoker's Success In Quitting
Porter Novelli, New York

Results of a new study show that using computer technology to tailor a mass produced program to individual smoker's needs doubles the success of quit smoking attempts with over-the-counter nicotine replacement therapy, reported researchers at the 10th World Conference on Tobacco or Health held in Beijing. The study sponsored by SmithKline Beecham Consumer Healthcare followed 3,800 US consumers who used Nicorette nicotine gum to stop smoking.

Released: 3-Sep-1997 12:00 AM EDT
Focus on Looks Puts Young Girls in Peril
Cornell University

A new book by Joan Jacobs Brumberg discusses how early menarche and new focus on body parts put young girls in peril. They have become so preoccupied with their bodies that they spend much of their energy managing and maintaining their looks at the expense of their creativity and mental and physical health, she says.

   
Released: 3-Sep-1997 12:00 AM EDT
Smoking increases severity of rheumatoid arthritis
University of Iowa

Cigarette smoking significantly worsens the symptoms of rheumatoid arthritis, according to University of Iowa College of Medicine researchers who studied the severity of the disease in more than 300 patients.

Released: 3-Sep-1997 12:00 AM EDT
UW sensors take chemical analysis out of the lab and into the field
University of Washington

Doctors needing chemical analyses such as blood tests to make life-saving diagnosis and treatment decisions soon won't have to lose precious time waiting for results to come back from the lab. New hand-held sensor technology developed at the University of Washington will allow physicians to bring a sophisticated "laboratory" directly to their patients for instant, on-site chemical analysis.

   
2-Sep-1997 12:00 AM EDT
Veterans With Gulf War Syndrome
American Academy of Otolaryngology - Head and Neck Surgery

Desert Storm veterans identified with Gulf War syndrome are more prone to suffer from significant balance problems, exhibiting symptoms consistent with a central nervous system disorder. This is the finding of a new research study conducted by Peter Roland, MD, and Robert W. Haley, MD, both from the University of Texas - Southwestern Medical Center, Dallas, TX.

2-Sep-1997 12:00 AM EDT
New Study: Some Army Drill Instructors Abuse their Vocal Cords, Resulting in Permanent Changes in Voice
American Academy of Otolaryngology - Head and Neck Surgery

A new study conducted in cooperation with the U.S. Army indicates that a number of U.S. Army drill instructors have a permanent change in their voices as the result of abusing their vocal cords. This research finding is being presented by Eric A. Mann, MD, of Rockville, MD.

2-Sep-1997 12:00 AM EDT
HIV--New Research Offers Guidelines For Diagnosis, Treatment of Ear, Nose, and Throat Disorders In HIV-Infected Patients
American Academy of Otolaryngology - Head and Neck Surgery

Ear, nose, and throat specialists have completed two new research studies regarding the diagnosis and treatment of otolaryngologic medical disorders in patients with HIV infection or AIDS. One study assesses the risks of otologic surgery to the HIV/AIDS patient; the second study identifies ear, nose, and throat disorders found among patients recently diagnosed with HIV.

2-Sep-1997 12:00 AM EDT
Penicillin-Resistant Streptococcus Pneumoniae (PRSP)
American Academy of Otolaryngology - Head and Neck Surgery

A new prospective study provides the first documentation that penicillin-resistant Streptococcus pneumoniae (PRSP) is a pathogen in causing otitis media with effusion (infection of the middle ear) in young children. The presence of PRSP is significant for this common childhood ailment is regularly treated with antibiotics and in some cases, the insertion of tympanostomy tubes.

2-Sep-1997 12:00 AM EDT
Technology That Reduces Snoring: Stanford University Research
American Academy of Otolaryngology - Head and Neck Surgery

Three months ago, newspapers and network television news reports featured a manufacturer's report of a system that delivers radiofrequency (RF) energy to obstructive tissue in the upper airway (passages at the back of the mouth and throat), resulting in a cost-effective, outpatient therapy to reduce snoring. Now, the research team that developed this system will present their findings for the first time to fellow otolaryngologists.



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