Nanoshuttle Wear and Tear: It’s the Mileage, Not the Age
Columbia University School of Engineering and Applied ScienceAs nanomachine design advances, researchers are moving from wondering if the nanomachine works to how long it will work—an important question as there are so many potential applications, e.g., for medical uses including drug delivery and early diagnosis. Columbia Engineering Professor Henry Hess observed a molecular shuttle powered by kinesin motor proteins and found it to degrade when operating, marking the first time degradation has been studied in detail in an active, autonomous nanomachine.