Do we really know how the brain works? In the last several decades, scientists have made great strides in understanding this fantastically complex organ. Scientists now know a great deal about the brain’s cellular neurobiology and have learned much about the brain’s neural connections, and the components that make up these connections.
Phenylketonuria (PKU) is a rare newborn genetic disease that impacts between 1 in 10,000 to 1 in 20,000 people, depending on the individuals’ genetic ancestry. PKU causes an amino acid—called phenylalanine (Phe)—to build up in the bloodstream.
Mount Sinai researchers have shed valuable light on the mechanism of a key protein that regulates the plasticity and function of the hippocampus, a key brain region involved in memory and learning, and that decreases with age in mice.
ASU bioengineer Benjamin Bartelle studies the innate immune system, which serves as the body’s first line of defense for many disease processes.
The American Academy of Sleep Medicine has formed a new Coalition for Permanent Standard Time to advocate for the introduction and adoption of federal legislation making standard time permanent across the U.S.
Researchers led by a team at UT Southwestern Medical Center have developed a device that can isolate blood flow to the brain, keeping the organ alive and functioning independent from the rest of the body for several hours.
Findings from researchers at the University of Michigan Health Rogel Cancer Center, published in Cancer Discovery, show how a specific nucleotide metabolite called GTP controls responses to radiation and chemotherapy in an unexpected way.
Case Western Reserve University has established an Institute for Glial Sciences to advance research of glial cells and their critical role in the health and diseases of the nervous systems, including multiple sclerosis, Alzheimer’s, pediatric leukodystrophies, Autism spectrum disorders, Parkinson’s disease and cancer.
Using nanoparticles administered directly into the cerebrospinal fluid (CSF), a research team has developed a treatment that may overcome significant challenges in treating a particularly deadly brain cancer.
People who live in neighborhoods with lower socioeconomic status are less likely to receive clot-busting medications or undergo clot-removing procedures after they have a stroke than people who live in neighborhoods with higher socioeconomic status, according to a study published in the November 1, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Cassandra Gipson-Reichardt, Ph.D., and Terry Hinds, Jr., Ph.D., associate professors in the University of Kentucky College of Medicine’s Department of Pharmacology and Nutritional Sciences, have received a $2.65 million five-year grant from the National Institute on Drug Abuse (NIDA) to support research to understand how xylazine and fentanyl change the brain’s signaling pathways.
Scientists at St. Jude Children’s Research Hospital determined structures of a transporter protein involved in the movement of neurochemicals such as serotonin and dopamine, unearthing multiple mechanisms that can guide drug development.
Dravet syndrome is a rare, severe epilepsy caused by certain changes in the SCN1A gene. But people with Dravet have a wide range of clinical characteristics that cannot be fully explained by these changes. What else is going on?
The test alone will not provide enough information to reach a diagnosis of memory problems/cognitive decline. Only a trained physician can do it.
Announcement of contents of the November 2023 issue of Neurosurgical Focus
In a detailed study published in the Journal of Alzheimer’s Disease November 3, 2023, we can finally see which diets are helpful in reducing the risk of developing Alzheimer’s disease.
A pioneering study at Umeå University, Sweden, has unveiled that the 3D organization of DNA can influence the progression of the aggressive brain tumour known as glioblastoma. Having identified the factors that glioblastoma uses to respond to neurons by growing and spreading, this discovery paves the way for further research into new treatments for brain tumours.
Le Plan d’action mondial intersectoriel sur l'épilepsie et les autres troubles neurologiques vise à réduire les écarts diagnostiques et de thérapeutiques de l'épilepsie dans le monde d'ici 2031. Mais dans la pratique, comment améliorer la prise en charge ?
Réduire la distance géographique entre les soins de l’épilepsie, les médicaments anticonvulsivants et les personnes atteintes d’épilepsie peut améliorer les résultats, selon un essai randomisé en grappes dans le nord de l’Inde.
Two studies led by UCLA researchers offer new insights into the way neurons in the human brain represent time and space – the most basic ingredients of consciousness of human existence and the primary dimensions of experience that allow us to reconstruct the past and envision the future.
Las cefaleas en brotes no son tan comunes, pero sí extremadamente dolorosas. Y suelen aparecer con el cambio de estación.
The largest brain autopsy study of women who had experienced intimate partner violence reveals substantial vascular and white matter damage in the brain, but no evidence of chronic traumatic encephalopathy (CTE), the neurodegenerative disease recognized among male contact sports athletes who sustain repeated head trauma.
Building upon the expertise in dementia research and care across Penn Medicine, the health system has been awarded a $5 million grant from the Delaware Community Foundation to support the Penn Institute on Aging’s (IOA) work to develop the next generation of therapies for Alzheimer’s disease and related dementias (ADRD).
Investigators have developed a new risk score that assesses a person’s risk for developing ALS, as well as for survival after diagnosis, using a blood sample based on exposure to toxins in the environment, a new study shows.
Previously, touch was thought to be detected only by nerve endings present within the skin and surrounding hair follicles.
The rise of the capabilities of artificial intelligence (AI) systems has led to the view that these systems might soon be conscious. However, we might underestimate the neurobiological mechanisms underlying human consciousness.
A research team from the Monell Chemical Senses Center demonstrated, using a novel quantitative analysis, that the neuronal response to odors undergoes some modifications in the nose. Such early processing of olfactory signals is a result of interactions between olfactory receptor neurons and the neighboring trigeminal neurons.
Up to 1.7 million people could be living with dementia in England and Wales by 2040 – over 40% more than previously forecast – finds a new UCL-led study.
Marissa Scavuzzo, a postdoctoral fellow at the Case Western Reserve University School of Medicine, has won the 2023 Eppendorf & Science Prize for Neurobiology for research in how glial cells in the intestine’s nervous system operate.
A new research study shows that cerebrospinal fluid reduces current treatment efficacy in brain cancer and identifies new therapeutic opportunities.
When Yale neuroscientist Joy Hirsch used sophisticated imaging tools to track in real time the brain activity of two people engaged in conversation, she discovered an intricate choreography of neural activity in areas of the brain that govern social interactions.
To help ensure that patients with active substance use disorder, on medication-assisted treatment, or in abstinent recovery continue to receive high-quality, safe pain management and anesthesia care, the American Association of Nurse Anesthesiology (AANA) has published its updated analgesia and anesthesia practice considerations.
Older people who have higher levels of triglycerides, a type of fat, may have a lower risk of dementia and a slower cognitive decline over time compared to people who have lower levels, according to new research published in the October 25, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.
People who have experienced traumatic events in childhood such as abuse, neglect or household dysfunction may be more likely to experience headache disorders as adults, according to a meta-analysis published in the October 25, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. This research does not prove that such experiences cause headaches; it only shows an association.
How do our brains take in complex information from the world around us to help us make decisions? And what happens when there’s a mismatch between how well your brain thinks it’s performing this function and how well it’s actually doing? In this episode of the UCI School of Social Sciences Experts On, cognitive scientist Megan Peters takes a deep dive into metacognition - our ability to monitor our own cognitive processing.
Researchers found that listening to our preferred music reduces pain intensity and unpleasantness, knowledge which could optimize music-based pain therapies
Post COVID-19 condition does not appear to be linked to direct viral invasion of the brain or active brain damage. This has been shown by a study at the University of Gothenburg. Searching for abnormal biomarkers among the participants yielded no hits in either blood or cerebrospinal fluid samples
This cutting-edge technique activates a specific neurotransmitter receptor using mid-infrared light, which can penetrate deep into tissue and offers unparalleled pharmacological and spatiotemporal precision in three dimensions.
In a mouse study designed to explore the impact of marijuana’s major psychoactive compound, THC, on teenage brains, Johns Hopkins Medicine researchers say they found changes to the structure of microglia, which are specialized brain immune cells, that may worsen a genetic predisposition to schizophrenia. The
Rutgers researchers find long-term users of cocaine may continue with unrewarding behavior because of changes in brain structure and chemistry responsible for generating an important teaching signal.
A Mount Sinai-led team of researchers has shed new light on the ways in which cocaine addiction dysregulates the normal function of dopamine neurons and thus the brain’s ability to process and respond to reward-related information, making it more difficult for individuals to change their addictive behaviors.
Tim Evans is participating in a clinical trial at Johns Hopkins Medicine, in collaboration with the Johns Hopkins University Applied Physics Laboratory, that is looking at a series of studies using the device in patients with severe speech and movement difficulties to regain some of the abilities lost due to neurological diseases.
Oct. Tipsheet - Sylvester’s top leader receives prestigious award, a pioneering physician is elected to the Neuro-Oncology Society’s board, an NCI grant funds research into lifestyle interventions for breast cancer patients, breast cancer and stress, teaming up with the Dolphins to battle breast cancer, physician burnout, more.
Schizophrenia is a severe neuropsychiatric disease that remains poorly understood and treated. Schizophrenia onset is typically in adolescence or early adulthood, but its underlying causes are thought to involve neurodevelopmental abnormalities.
Curiosity paradoxically increases people’s patience for an answer, while simultaneously making them more eager to hear it, finds a new study by Duke neuroscientists.
The Hackensack Meridian Neuroscience Institute at Jersey Shore University Medical Center recently added the new Siemens Healthineers ARTIS icono biplane system to its interventional imaging services thanks to an extraordinarily generous gift from Mrs. Mary Ellen Harris and the Golden Dome Foundation.
Read the latest research news on air pollution, nanoplastics, waterborne illnesses and more in the Pollution channel on Newswise.
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