Mammal cells could struggle to fight space germs
University of ExeterThe immune systems of mammals - including humans - might struggle to detect and respond to germs from other planets, new research suggests.
The immune systems of mammals - including humans - might struggle to detect and respond to germs from other planets, new research suggests.
CAR-T cell therapy, which attacks cancer cells using a person’s reprogrammed immune cells, has been used to treat Hodgkin lymphoma with remarkable success for the first time, according to the results of an early phase clinical trial.
• Studies conducted in mouse models, patients with cystic fibrosis, and different types of cells have helped to define how cystic fibrosis affects the kidneys. • A urine test may help to assess aspects of cystic fibrosis in patients, which may be useful for testing the effectiveness of new medications.
Taking a bottom-up approach to synthetic biology, UC San Diego chemists and physicists show that lipid sponge droplets can be programmed to internally concentrate specific proteins, host and accelerate biochemical transformations and control enzymatic reactions.
Small farms in Zambia that use the latest hybrid seed for maize, help reduce deforestation and tackle climate change in a new Cornell University study.
As several Neandertal genomes of high quality are now available researchers can identify genetic changes that were present in many or all Neandertals, investigate their physiological effects and look into their consequences when they occur in people today.
Researchers at the Smithsonian Tropical Research Institute (STRI) in Panama have published dramatic maps showing the locations of lightning strikes across the tropics in Global Change Biology.
Researchers from BIDMC report on the decline of emergent medical, surgical and obstetric hospitalizations at the medical center during the six-week period following the week of the declaration of the COVID-19 public health emergency in Boston in mid-March 2020.
Florida State University researchers have new insight into the tiny packages that cells use to move molecules, a structure that is key to cellular metabolism, drug delivery and more.
While most of the business world builds success from existing relationships, four scientists including Xiumin Martin from the Olin Business School at Washington University in St. Louis crunched 12 years' worth of data to find that personal connections between suppliers and vendors particularly improves the efficiency of the supply chain. To be precise, such rapport results in better overall performance, less restrictive and longer-lasting contract terms, and crystallized communication.
One in 11 flowers carries disease-causing parasites known to contribute to bee declines, according to a Cornell University study that identifies how flowers act as hubs for transmitting diseases to bees and other pollinators.
Many Black men suffer symptoms of traumatic stress in the aftermath of traumatic injury, and they also often carry social concerns, including experiences of discrimination and stigma. Yet despite their significant needs, underserved populations often have limited access to behavioral health care as well as a lack of financial resources to pay for such care. Because of these barriers, many trauma survivors do not seek professional behavioral health care and instead rely on informal or alternative sources of care.
According to an open-access article published in ARRS' American Journal of Roentgenology (AJR), lung ultrasound (US) was highly sensitive for detecting abnormalities in patients with coronavirus disease (COVID-19), with B-lines, a thickened pleural line, and pulmonary consolidation the most commonly observed features.
A new study finds teen docents at museums have an overall positive effect on visitor experiences, learning and information retention. The positive effects accrued across age groups regardless of museum type, but were most apparent in children ages 9 to 11.
The best footballers (soccer players) have a high degree of passion and grit.
Hotels should build an emotional attachment with tourists when communicating during crises such as the COVID-19 pandemic if they are to encourage them to return, according to new research.
For the first time, the raw genetic material that codes for bats' unique adaptations and superpowers such as the ability to fly, to use sound to move effortlessly in complete darkness, to survive and tolerate deadly diseases, to resist ageing and cancer - has been fully revealed.
Though many people find them intimidating, menacing or just plain scary, sharks are vital to the health of the world's oceans.
Disorganized efforts to implement artificial intelligence in hospitals could undermine the technology's vast potential to benefit patients, the group warns.
Research from the University of Notre Dame shows it is often best for optimal efficiency if the minority group is overrepresented in the workforce relative to the majority — a conclusion that flies in the face of the conventional wisdom that affirmative action will eventually be obsolete.
In two separate studies, the University of Delaware’s Kathryn Coyne is looking at why one species of algae has some strains that can cause fish kills and others that are non-toxic, while examining an algicidal bacterium found in Delaware’s Inland Bays that could provide an environmentally-friendly approach to combatting algae blooms.
New recommendations call for more evidence-based workforce training to meet the growing demands for dementia care.
DALLAS – July 23, 2020 – Deleting a key gene in mice in just their fat made tissues throughout these animals insulin resistant, in addition to other effects, a new study by UT Southwestern researchers shows. The findings, reported in a recent issue of PNAS, could shed light on Type 2 diabetes and other insulin resistance disorders, which remain poorly understood despite decades of study.
Researchers at Washington University School of Medicine in St. Louis have combined two immunotherapy strategies into a single therapy and found, in studies in human cells and in mice, that the two together are more effective than either alone in treating certain blood cancers, such as leukemia.
A Penn State College of Medicine research team found that playing a simple conversation game may encourage African Americans to make plans for their end-of-life care.
A new cell profiling technology combines high throughput imaging and machine learning to provide a rapid, cost-effective way to determine how specific compounds act to destroy the bacterium that causes tuberculosis. It could speed discovery of anti-TB drugs and be applied to other pathogens.
How accurate was William Shakespeare when he said, "'Tis better to have loved and lost than never to have loved at all,"? Researchers from Michigan State University conducted one of the first studies of its kind to quantify the happiness of married, formerly married and single people at the end of their lives to find out just how much love and marriage played into overall well-being.
A Cornell University-led collaboration has used state-of-the-art computational tools to model the chaotic behavior of Planckian, or “strange,” metals. This behavior has long intrigued physicists, but they have not been able to simulate it down to the lowest possible temperature until now.
Texas Biomedical Research Institute (Texas Biomed) scientists have added another tool to the COVID-19 toolbelt, validating a new small animal model for studying SARS-CoV-2, the virus that causes COVID-19.
The inflammatory molecule interleukin-17A (IL-17A) triggers immune cells that in turn reduce IL-17A’s pro-inflammatory activity, according to a study by National Eye Institute (NEI) researchers.
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our “COVID-19 Tip Sheet: Story Ideas from Johns Hopkins” every Tuesday throughout the duration of the outbreak.
Although rates of surgery for Crohn’s disease have decreased over the years, many patients still require surgical treatment – due to inadequate responses to medical therapy, severe attacks of acute colitis, and many other situations. Reflecting the latest research evidence and clinical practice, an updated set of recommendations for surgery in patients with Crohn’s disease have been published in Diseases of the Colon & Rectum (DC&R), the official journal of the American Society of Colon and Rectal Surgeons (ASCRS). The journal is published by Wolters Kluwer.
Friends’ drinking behaviors may be key to risky drinking among pregnant teens and young adults, according to a new study. Researchers used a previously untried approach to examine the ways that adolescents’ and young adults’ alcohol use and beliefs before they become pregnant related to their drinking as they entered into motherhood. Young mothers may be particularly vulnerable to moderate or heavy drinking during pregnancy, with adverse outcomes for their babies. Understanding the factors that influence risky alcohol use in pregnancy (3+ drinks per occasion) is important for identifying and supporting at-risk teens and young adults. The study in Alcoholism: Clinical & Experimental Research may be the first to use data collected before pregnancy, minimizing inaccurate recall.
Long-term heavy drinking and alcohol dependence are linked to multiple health problems, including premature death. The risk of serious harm is higher for women than men, and also depends on the person’s current level of drinking. However, it is not known if other factors, such as previous drinking history and co-existing psychiatric conditions, might also contribute to early death in people with alcohol dependence. One way to evaluate the impact of these factors is to group patients based on clusters of characteristics and assess outcomes in each group. Alcohol dependence ‘subtypes’ have previously been used to group patients for treatment planning purposes, but have not been assessed for their role in predicting long-term outcomes of alcohol dependence. A new study, reported in Alcoholism: Clinical and Experimental Research, has evaluated four alcohol dependence subtypes as predictors of relapse in the year after treatment, and as predictors of mortality over 36 years of follow-up.
Scientists are harnessing the mind-bending potential of quantum computers to help us understand genetic diseases – even before quantum computers are a thing. ]
Not long after the Coronavirus disease (Covid-19) outbreak in China, Italy was hard-hit by the infection and rapidly became one of the countries with the highest mortality rate.
Unique geography allows for wide variety of soils
Research suggests the economic loss from wheel-traffic compaction for farmers in North Dakota and Minnesota could exceed 1 billion USD
A new study suggests that communication between skeletal muscle cells and muscle fibers promotes muscle growth. Adult muscle stem cells, called satellite cells, release extracellular vesicles that are delivered to muscle fibers responsible for contraction, to promote this muscle growth. The first-of-its-kind study is published ahead of print in the journal Function.
Adolescents and young women with disabilities can stop periods and get relief from distressing menstrual symptoms with IUDs, in the largest study in this population to date.
Researchers investigating plant defenses—from threats spanning insects to pathogens—have discovered an “on-off” switch. The finding lays the groundwork for improved plant disease resistance and food stability.
Just a few negative online restaurant reviews can determine early on how many reviews a restaurant receives long-term, a new study has found.
Post-surgical bleeding is associated with more deaths than blood clots from surgery, according to a Vanderbilt University Medical Center study published in the journal Anesthesia & Analgesia.
Authors of a new perspective on health inequities say that, in addition to health policy and individual-level efforts, social policy solutions are needed. They identify two key lessons from the pandemic: public policy enables public health and health equity requires big investments in public policy.
In a new study, “Pediatric vestibular schwannomas: case series and a systematic review with meta-analysis,” appearing in the Journal of Neurosurgery, researchers at Loyola University Medical Center and Loyola University Chicago Stritch School of Medicine performed a retrospective review of the diagnosis, treatment and outcomes of 15 patients (21 years of age or younger) with unilateral vestibular schwannomas, without neurofibromatosis type 2 (a genetic disorder that causes noncancerous tumor growth in the nervous system), who underwent surgery at Loyola University Medical Center between 1997 and 2019. The study authors also reviewed existing literature on this type of tumor in pediatric patients. Overall, the review found that pediatric patients had similar symptoms to those of adult patients with acoustic neuromas; however, the tumor size was typically larger in the pediatric patients at the time of diagnosis, and symptoms of mass effect (secondary effects caused by the tumor) were
Researchers are studying how the collapse of microbubbles within the skull can damage brain cells. Their research could lead to the design of better helmets.
Why do some people stay sharp into their 90s, even if they have the amyloid plaques in the brain that are associated with Alzheimer’s disease? And why do others reach their 90s without ever developing any plaques? These questions are explored in a new study published in the July 22, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology.