Middle-age veterans who experienced concussions due to blasts from explosive devices may have biomarkers in their spinal fluid similar to people who develop Alzheimer’s disease, according to a new study published in the March 13, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Gait impairments often are prevalent in the early stages of cognitive decline. Researchers quantitatively compared straight walking and curved walking – a more natural yet complex activity – in healthy older adults and adults with mild cognitive impairment (MCI). A depth camera detected and tracked 25 joints of body movement and signals were processed to extract 50 gait markers. Intriguingly, curved walking illuminated notable disparities between the study groups.
Monitoring daily activity patterns using a wrist-worn device may detect early warning signs of Alzheimer’s disease, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health.
Dementia may be three times more common among people with essential tremor, a movement disorder that causes involuntary shaking, than the general population, according to research released today, March 6, 2024. The study will be presented at the American Academy of Neurology’s 76th Annual Meeting taking place April 13–18, 2024, in person in Denver and online.
New Cleveland Clinic-led research points to sildenafil (Viagra) as a potential treatment for Alzheimer’s disease. The study provides evidence from computational models, insurance claims data and observations from brain cells in Alzheimer’s patients. Sildenafil is the main component of drugs used to treat erectile dysfunction (Viagra) and pulmonary arterial hypertension (Revatio).
Four University of Michigan research teams have made the bracket of 64 teams for STAT Madness, a virtual tournament of science. They were picked for their groundbreaking work on brain cancer, heart transplant, dementia care and deadly fungal infections published in 2023.
Alzheimer’s disease and Type 2 diabetes are part of a family of amyloid diseases that are characterized by having proteins that cluster together. University of Washington researchers have demonstrated more similarities between the two diseases.
Continuous, unobtrusive sensors and related monitoring devices are installed in older drivers’ vehicles to detect changes in highly complex activities over time. A driver facing camera, forward facing camera, and telematics unit provide video in real-time to enable researchers to analyze abnormal driving such as getting lost, reaction time and braking patterns as well as travel patterns such as miles driven, miles during the night and daytime, and driving in severe weather. Detecting changes in behavior could generate early warning signs of possible changes in cognition.
Researchers at Washington University School of Medicine in St. Louis have found that brain cell activity during sleep is responsible for propelling fluid into, through and out of the brain, cleaning it of debris.
Researchers at the Icahn School of Medicine at Mount Sinai and others have harnessed the power of machine learning to identify key predictors of mortality in dementia patients. The study, published in the February 28 online issue of Communications Medicine, addresses critical challenges in dementia care by pinpointing patients at high risk of near-term death and uncovers the factors that drive this risk. Unlike previous studies that focused on diagnosing dementia, this research delves into predicting patient prognosis, shedding light on mortality risks and contributing factors in various kinds of dementia.
UC Santa Barbara researchers and collaborators in Colombia, Brazil and Germany are progressing toward an understanding of mechanisms that underlie Alzheimer’s disease, in particular an early-onset, genetic form that has afflicted generations of an extended family in Colombia.
As we get older, we may start to notice it takes us longer to find the right words. This can lead to concerns about cognitive decline and dementia.
The impact of abdominal fat on brain health and cognition is generally more pronounced in middle-aged men at high risk of Alzheimer’s disease as opposed to women, according to researchers at Rutgers Health.
Two new studies from the University of Chicago investigate the roles of the gut microbiome and estrogen in the differing rates of Alzheimer’s disease among women and men.
Neuroscientist Emily Rogalski, PhD, is a principal investigator on a grant from the NIH to support a clinical trial of a telehealth intervention for primary progressive aphasia (PPA).
A new UCLA Health study found Kundalini yoga provided several benefits to cognition and memory for older women at risk of developing Alzheimer’s disease including restoring neural pathways, preventing brain matter decline and reversing aging and inflammation-associated biomarkers – improvements not seen in a group who received standard memory training exercises.
People with higher exposure to traffic-related air pollution were more likely to have high amounts of amyloid plaques in their brains associated with Alzheimer’s disease after death, according to a study published in the February 21, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Stay informed! These are the latest research articles on "Long COVID" from the Coronavirus News Source on Newswise.
Researchers at West Virginia University have identified a set of diagnostic metabolic biomarkers that can help them develop artificial intelligence tools to detect Alzheimer’s disease in its early stages, as well as determine risk factors and treatment interventions.
A team led by scientists at the Case Western Reserve University School of Medicine has identified a new therapeutic approach for combating neurodegenerative diseases.
Rutgers study led by undergrads and gap-year students breaks ground in the field of neuroscience and suggests experimental medication could treat dementia.
Neuroscientists at Macquarie University in Australia have developed a single-dose genetic medicine that has been proven to halt the progression of both ALS and frontotemporal dementia (FTD) in mice – and may even offer the potential to reverse some of the effects of the fatal diseases.
Professor Eef Hogervorst, Professor of Biological Psychology at Loughborough University, sits down to discuss the factors influencing the menopause, what the best treatment options are, the relationship between oestrogen and dementia, and the controversies surrounding the andropause (the ‘male menopause’).
A new study has laid the groundwork for a future intervention designed to help caregivers establish a safe and workable mealtime routine for people with dementia living at home.
Irvine, Calif., Feb. 14, 2024 — A research team led by the University of California, Irvine has created 20 new recombinant rabies viral vectors for neural circuit mapping that offer a range of significant advantages over existing tools, including the ability to detect microstructural changes in models of aging and Alzheimer’s disease brain neurons.
Clinical studies suggest the Mediterranean diet, and one of its main components, extra virgin olive oil (EVOO), improves cognitive function and slows Alzheimer's disease (AD) progression. Researchers will now investigate whether this is true even for people with a family history of AD and signs of genetic predisposition caused by dysfunction in the APOE gene.
A team of scientists from Wake Forest University School of Medicine and the University of Southern California (USC) have demonstrated the first successful use of a neural prosthetic device to recall specific memories.
Below are some of the latest research and features on this growing population of older adults in the Seniors channel on Newswise.
Immigrants living with dementia were more likely to present with agitation and aggression compared with their non-immigrant counterparts, a new study by Edith Cowan University (ECU) in collaboration with The Dementia Centre, HammondCare, found.
Improving the way scientists can see the microscopic structures of the brain can improve our understanding of a host of brain diseases, like Alzheimer’s or multiple sclerosis. Studying these diseases is challenging and has been limited by accuracy of available models.To see the smallest parts of cells, scientists often use a technique called electron microscopy.
In an effort five years in the making, UNC School of Medicine cell biologist Sarah Cohen, PhD, and Rockefeller University’s Ian Windham, PhD, describe the interplay between fats and proteins in brain cells and how their dysfunction contributes to the development of late-onset Alzheimer’s disease.
University Hospitals Brain Health & Memory Center is now treating patients with LEQEMBI® (lecanemab), a Food and Drug Administration-approved medication for the treatment of Alzheimer’s disease.
Rutgers Health researchers find differences among Asian older adults’ support of research and inclination to receive MRI results.
The drugs used to treat erectile dysfunction may also be associated with a reduced risk of Alzheimer’s disease, according to a study published in the February 7, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Designing sensitive and single-use biosensors for early diagnosis remains a major challenge. Scientists in China invented submonolayer lasers on optical fibers as ultrasensitive and disposable biosensors.
A potential new drug to prevent Alzheimer’s disease in people with the so-called Alzheimer’s gene has been discovered by a University of Arkansas for Medical Sciences (UAMS) research team led by Sue Griffin, Ph.D.
Two Rutgers professors, both leading Alzheimer's disease researchers, have partnered with Tel Aviv University and Hebrew University to organize the US-Israel Alzheimer’s Disease Conference in Tel Aviv.
Researchers have discovered why a gene that, when mutated, is a common cause of two debilitating brain diseases.
Since its introduction to the public in November 2022, ChatGPT, an artificial intelligence system, has substantially grown in use, creating written stories, graphics, art and more with just a short prompt from the user.
Nicolas Musi, MD, studies a spectrum of age-related disorders that can impact a healthy lifespan.
A team of University of Wisconsin–Madison scientists has developed the first 3D-printed brain tissue that can grow and function like typical brain tissue.
Hydrogen peroxide is crucial in cell metabolism, playing key roles in cell proliferation, differentiation, and migration. However, elevated levels of hydrogen peroxide (H2O2) are linked to several diseases, including cancer and neurodegenerative disorders like Alzheimer's and Parkinson's disease.
Left unchecked, hearing loss can lead to lead to social isolation and depression – two conditions proven to hasten dementia. A Penn State Health expert sounds off on what you can do about it.
University at Albany scientist Scott Tenenbaum, founder of UAlbany spinoff company sxRNA Technologies, Inc. (sxRNA Tech), has received $500,000 from the National Institute on Aging, part of the National Institutes of Health, to study how aging brain cells shape the progression of Alzheimer’s disease, and advance RNA technology that could inform new therapeutics to prevent and treat Alzheimer's and related dementias.
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