For the first time, researchers in the University of Georgia's Regenerative Bioscience Center have used an imaging method normally reserved for humans to analyze brain activity in live agricultural swine models, and they have discovered that pig brains are even better platforms than previously thought for the study of human neurological conditions such as Alzheimer’s and Parkinson’s.
A team of researchers from McMaster University has mapped at atomic resolution a toxic protein linked to Alzheimer’s disease, allowing them to better understand what is happening deep within the brain during the earliest stages of the disease.
New research may explain why an antioxidant that protects the brain is associated with deterioration in areas susceptible to Alzheimer’s disease. Superoxide dismutase improves cognition, but its protective benefits weaken when levels of tau proteins – a hallmark of Alzheimer’s disease – increase.
An increasing number of studies are finding intimate communication between the gut and brain, as well as complex interplay among the gut microbiome, the brain and the rest of the body. But does the gut affect epilepsy? More specifically, can certain populations of bacteria predispose to seizures, and can we harness the power of the microbiome to stop seizures?
An international research team led by scientists at UAB has identified a fibril form of alpha-synuclein as a potential target for therapeutics that might help slow the progression of Parkinson’s disease.
In a search for clues to what may delay or prevent Alzheimer’s disease, Johns Hopkins Medicine scientists report that smarter, more educated people aren’t protected from the disease, but do get a cognitive “head start” that may keep their minds functioning better temporarily.
When Guy Bradley began having episodes of memory loss and confusion, doctors suspected a stroke or dementia. Instead, an EEG showed that the 69-yeard old epilepsy, which is frequently missed in older patients because it's presumed to be a "children's disease."
A new study finds that people who have movement problems, symptoms that cannot be explained by an underlying disease, may have chemical changes in specific areas of the brain. The study is published in the June 5, 2019, online issue of Neurology®, the medical journal of the American Academy of Neurology. These symptoms, which include tremors, muscle contractions or problems with walking, are called functional or psychogenic motor symptoms.
If you're looking for health and fitness story ideas, view these research highlights from the May 2019 issue of Medicine & Science in Sports & Exercise®, ACSM’s flagship journal. ACSM is the largest sports medicine and exercise science organization in the world.
The researchers have determined that gum disease (gingivitis) plays a decisive role in whether a person developes Alzheimer´s or not.
Georgetown University Medical Center announces the launch of the only known therapeutic (disease modifying) clinical trial for Lewy body dementia, a neurological disorder that affects a million people in the United States for which there are no approved medications that modify the disease.
A new study indicates that racism is toxic to humans.
Researchers with the Atlanta Veterans Affairs Medical Center and Emory University have found a link between high LDL cholesterol levels and early-onset Alzheimer's disease.
Something as simple as a phone call could be a way to alert health care providers and caregivers that an elderly person suffering from dementia may be spiraling down to dangerous self-neglect, according to researchers at The University of Texas Health Science Center at Houston (UTHealth).
Aging adults often show signs of slowing when it comes to managing their finances, such as calculating their change when paying cash or balancing an account ledger. But trouble managing money can also be a harbinger of dementia and, according to new Duke research in The Journal of Prevention of Alzheimer’s Disease, could be correlated to the amount of protein deposits built up in the brain.
New research indicates that older patients who develop delirium— an acute attentional deficit that waxes and wanes —right after surgery are more likely to show signs of postoperative cognitive dysfunction one month later
Researchers examining post-mortem brain tissue from people ages 79 to 99 found that new neurons continue to form well into old age. The study provides evidence that this occurs even in people with cognitive impairment and Alzheimer’s disease, although neurogenesis is significantly reduced in these people compared to older adults with normal cognitive functioning.
Targeting a key gene before birth could someday help lead to a treatment for Down syndrome by reversing abnormal embryonic brain development and improving cognitive function after birth, according to a Rutgers-led study.
A new study by Stony Brook University researchers reveals that higher education is associated with later onset of Alzheimer’s-related accelerated cognitive declines. Their findings will be published early online in the Journal of Gerontology.
Memorial Day Travel Tips for Families Impacted by Alzheimer's Disease
UNLV researchers have discovered a novel method for how two parts of the brain — the hippocampus and the anterior cingulate cortex (ACC) — work together to retrieve long-term memories.
Roughly four out of five people won’t ever experience memory issues more serious than the “senior moments” of normal aging.
Researchers at UC Davis Health and UC San Francisco have found a way to teach a computer to detect one of the hallmarks of Alzheimer’s disease
Many Americans in their 50s and early 60s are worried about declining brain health, especially if they have loved ones with memory loss and dementia, a new national poll finds. But while the majority of those polled say they take supplements or do puzzles in an effort to stave off brain decline, very few of them have talked with their doctors about evidence-based ways to prevent memory loss. So they may miss out on proven strategies to keep their brains sharp into their later years.
Researchers at UC Davis and UC San Francisco have found a way to teach a computer to precisely detect one of the hallmarks of Alzheimer’s disease in human brain tissue, delivering a proof of concept for a machine-learning approach to distinguishing critical markers of the disease.
Scientists might have found an early detection method for some forms of dementia
A new clinical trial at The Ohio State University Wexner Medical Center and two other sites is testing an innovative procedure that may provide hope in the fight against Alzheimer’s disease. The non-invasive procedure uses low-intensity focused ultrasound to open the blood-brain barrier.
**Note to journalists: Michael Miller, Ph.D., will discuss this research at the Johns Hopkins Science Writers’ Boot Camp on June 10 at the National Press Club in Washington, D.C. Learn more and register for the free, daylong immersion in topics about mental health and addiction.
Researchers at The University of Chicago have demonstrated that the type of bacteria living in the gut can influence the development of Alzheimer’s disease symptoms in mice. The study, which will be published May 16 in the Journal of Experimental Medicine, shows that, by altering the gut microbiome, long-term antibiotic treatment reduces inflammation and slows the growth of amyloid plaques in the brains of male mice, though the same treatment has no effect on female animals.
بالتعاون مع جامعة كنتاكي، والمركز الطبي لجامعة جنوب غرب تكساس الطبية، والمركز الطبي لجامعة راش، وجامعة كامبردج في المملكة المتحدة، وغيرها من المؤسسات، ساعد باحثو Mayo Clinic في صياغة اسم لمرض الدماغ التنكسية الذي يصيب كبار السن ويحاكي ملامح داء الزهايمر
Em colaboração com a Universidade de Kentucky, Centro Médico da Universidade de Texas Southwest, o Centro Médico da Universidade Rush e a Universidade de Cambridge no Reino Unido, entre outras instituições, os pesquisadores da Mayo Clinic ajudaram a estabelecer um nome para uma doença cerebral degenerativa que aflige os idosos e imita características da doença de Alzheimer.
Virtual reality (VR) technology could vastly improve the quality of life for people with dementia by helping to recall past memories
Los investigadores de Mayo Clinic, en colaboración con la Universidad de Kentucky, el Centro Médico Suroccidental de la Universidad de Texas, el Centro Médico de la Universidad de Rush, la Universidad de Cambridge en el Reino Unido y otras instituciones, ayudaron a establecer el nombre de una enfermedad cerebral degenerativa que afecta a los ancianos e imita las características de la enfermedad de Alzheimer.
Luke Montrose, assistant professor in the Department of Community and Environmental Health, has been awarded a grant from the IDeA Network of Biomedical Research Excellence (Idaho INBRE) to fund a two-year pilot study related to Alzheimer’s disease.
“魔法漱口水”是一种含有苯海拉明、利多卡因和抗酸剂的漱口水，在为治疗头颈部癌症而接受放射治疗的患者中，其相比安慰剂可显著减轻口腔粘膜炎和口腔溃疡引起的疼痛。该发现来源于一项多机构参与、随机双盲、安慰剂对照的III期临床试验，该试验由Mayo Clinic的名誉放射肿瘤学家Robert Miller医学博士领导。
A study in mice shows that selectively removing cells that are no longer dividing from the brains of mice with a form of Alzheimer’s disease can reduce brain damage and inflammation, and slow the pace of cognitive decline. These findings, say researchers, add to evidence that such senescent cells contribute to the damage caused by Alzheimer’s disease in people.
The Dementia Friendly Hospital Initiative will reach a total of 3,900 employees in four hospitals across North Carolina to raise awareness of how patients with dementia experience care, and to meet their unique needs with strategic and compassionate treatment.
In collaboration with the University of Kentucky, the University of Texas Southwest Medical Center, Rush University Medical Center, the University of Cambridge in the U.K., and other institutions, Mayo Clinic researchers helped to establish a name for a degenerative brain disease that afflicts the elderly and mimics features of Alzheimer’s disease. This working group describes "limbic-predominant age-related TDP-43 encephalopathy," or LATE, as an underrecognized risk for public health and calls for an urgent focus on research to improve prevention, diagnosis and treatment of the disease. The report appears in the journal, Brain.
A brain disorder that mimics symptoms of Alzheimer’s disease has been defined with recommended diagnostic criteria and guidelines for advancing future research on the condition. Researchers at Rush University Medical Center and scientists from several National Institutes of Health-funded institutions, in collaboration with international peers, described the newly-named pathway to dementia, Limbic-predominant Age-related TDP-43 Encephalopathy, or LATE, in a report published today in the journal Brain.
Alzheimer's is dementia, but not all dementias are Alzheimer's (which may explain why so many Alzheimer's drugs have failed in clinical trials). A study published in Brain provides a framework for a newly characterized form of dementia called LATE.
A new Michigan State University study suggests that older adults with poor sense of smell may see an almost 50% increase in their risk of dying within 10 years – surprisingly in healthier individuals.
As May is the national awareness month for both Amyotrophic Lateral Sclerosis and Huntington’s disease, the American Neurological Association is highlighting recent research on these conditions that has appeared in its publications, the Annals of Neurology and the Annals of Clinical and Translational Neurology.
A new chemical synthesis strategy to harvest rich information found in natural products has led to identifying simpler derivatives with potential to selectively protect neurons -- important for such diseases as Alzheimer’s -- or to prevent the immune system from rejecting organ transplants.
Michigan Medicine (University of Michigan) researchers identify a potential therapeutic target for neurodegenerative conditions ALS and frontotemporal dementia, using animal models.
“Is amyloid precursor protein the mastermind behind Alzheimer’s or is it just an accomplice?” Researchers devised a multi-functional reporter for amyloid precursor protein and tracked its localization and mobility, noticing a strange association between the protein and cholesterol that resides in the cell membrane of synapses. With cholesterol’s broad involvement in almost all aspects of neurons’ life, they propose a new theory on the amyloid precursor protein connection in AD, especially in the surface of those tiny synapses, which triggers neurodegeneration.
In a small, pilot study, a non-invasive device that uses magnetic fields to stimulate nerve cells in the brain was associated with temporary improvements in age-related memory loss in older people, according to a study published in the April 17, 2019, online issue of Neurology®, the medical journal of the American Academy of Neurology.
A team led by researchers at the University of Washington has developed synthetic peptides that target and inhibit the small, toxic protein aggregates that are thought to trigger Alzheimer's disease.
Learning how to tie a shoe or shoot a basketball isn’t easy, but the brain somehow integrates sensory signals that are critical to coordinating movements so you can get it right. Now, Rutgers scientists have discovered that sensory signals in the brain’s cerebral cortex, which plays a key role in controlling movement and other functions, have a different pattern of connections between nerve cells and different effects on behavior than motor signals. The motor area of the cortex sends signals to stimulate muscles.
For decades, articles in research journals and the popular press alike have reported that being a family caregiver takes a toll on a person’s health, boosting levels of inflammation and weakening the function of the immune system. Now, after analyzing 30 papers on the levels of immune and inflammatory molecules in caregivers, Johns Hopkins researchers say the link has been overstated and the association is extremely small. Caregiver stress explains less than 1 percent of the variability in immune and inflammation biomarkers, they report. Their new meta-analysis was published March 10 in The Gerontologist.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right