A 21st-century remedy for missed meds
Rice UniversityMissing crucial doses of medicines and vaccines could become a thing of the past thanks to Rice University bioengineers’ next-level technology for making time-released drugs.
Missing crucial doses of medicines and vaccines could become a thing of the past thanks to Rice University bioengineers’ next-level technology for making time-released drugs.
The financial terms of biotechnology licenses from academic institutions are significantly less favorable than those of comparable licenses between commercial firms according to a new study from Bentley University’s Center for Integration of Science and Industry.
The kidney plays a vital role in maintaining homeostasis within the body by eliminating toxic and superfluous substances in the bloodstream, including waste generated during metabolic processes, through urine.
Researchers at the University of Washington have developed GlucoScreen, a system that could enable people to self-screen for prediabetes.
New research from Oregon Health & Science University and collaborators indicates lab-made antibodies may be able to cure people infected with yellow fever, a virus for which there is no treatment.
The Sbarro Health Research Organization (SHRO), led by Prof. Antonio Giordano, in collaboration with the Texas Scientific Italian Community (TSIC), led by Prof. Andrea Giuffrida, will present the XVII Conference of Italian Researchers in the World on Saturday April 1st from 9:30 AM to 3:00 PM at Temple University of Philadelphia.
Bioactive compounds present mostly in fruit and vegetables perform different bodily functions relating to health and well-being. Their effects are considered antioxidant, antidiabetic, antiaging and anticancer, among others.
From septic shock to sticker shock. Keep up with this ever-growing, changing sector. Below are some of the latest stories on healthcare on Newswise.
In Biophysics Reviews, researchers identify the most promising advancements and greatest challenges of artificial mitochondria and chloroplasts. The team describes the components required to construct synthetic mitochondria and chloroplasts and identifies proteins as the most important aspects for molecular rotary machinery, proton transport, and ATP production. The authors believe it is important to create artificial cells with biologically realistic energy-generation methods that mimic natural processes; replicating the entire cell could lead to future biomaterials.
Cardiomyopathy is a pathological condition characterized by cardiac pump failure due to myocardial dysfunction and the major cause of advanced heart failure requiring heart transplantation. Although optimized medical therapies have been develop
Ischemic stroke (IS) is the most prevalent form of brain disease, characterized by high morbidity, disability, and mortality. However, there is still a lack of ideal prevention and treatment measures in clinical practice. Notably, the transplan
Osteoporosis is a systemic bone disease, which leads to decreased bone mass and an increased risk of fragility fractures. Currently, there are many anti-resorption drugs and osteosynthesis drugs, which are effective in the treatment of osteopor
BACKGROUNDThe low survival rate of mesenchymal stem cells (MSCs) caused by anoikis, a form of apoptosis, limits the therapeutic efficacy of MSCs. As a proapoptotic molecule, mammalian Ste20-like kinase 1 (Mst1) can increase the production of re
For nearly 20 years, dental stem cells (DSCs) have been successfully isolated from mature/immature teeth and surrounding tissue, including dental pulp of permanent teeth and exfoliated deciduous teeth, periodontal ligaments, dental follicles, a
Most of the time, when someone gets a cut, scrape, burn, or other wound, the body takes care of itself and heals on its own. But this is not always the case. Diabetes can interfere with the healing process and create wounds that will not go away and that could become infected and fester.
An international research team has developed a meta-scale approach to quantifying the human proteome and the massive number of protein variants produced by the human body. Proteomics is a cornerstone of biology and a precursor to understanding how protein dysfunction contributes to disease.
A team of MIT researchers has come up with a kind of tiny, biodegradable tag that can be applied directly to the seeds themselves, and that provides a unique randomly created code that cannot be duplicated.
Staphylococcus aureus, Clostridioides difficile, Candida auris, Drug-resistant Shigella. These bacteria not only have difficult names to pronounce, but they are also difficult to fight off. These bacteria may infect humans and animals, and the infections they cause are harder to treat than those caused by non-resistant bacteria. Antimicrobial resistance is an urgent global public health threat.
The Center for Bioenergy Innovation has been renewed by the Department of Energy as one of four bioenergy research centers across the nation to advance robust, economical production of plant-based fuels and chemicals. CBI, led by Oak Ridge National Laboratory, is focused on the development of nonfood biomass crops and specialty processes for the production of sustainable jet fuel to help decarbonize the aviation sector.
Researchers at The Ohio State University have fabricated the first wearable sensor designed to detect and monitor muscle atrophy.
Keck Medicine of USC has launched a Phase 2 clinical trial investigating the effectiveness of a new outpatient, nonsurgical endoscopic procedure in stabilizing blood glucose levels for patients.
Scientists at University of Utah Health led research that opens up a whole new world within our cells. Their study uncovers a vast network of interactions that assist cells in adjusting in real time to withstand stresses on our health.
The paper ‘Weaponising microbes for peace’ by Anand et al, outlines the ways in which microbes and microbial technologies can be used to tackle global and local challenges that could otherwise lead to conflict, but warns that these resources have been severely underexploited to date.
Scientists previously believed that microorganisms could not use pyrite to grow in oxygen-free conditions. New research shows that certain single-celled microorganisms can dissolve pyrite in the absence of oxygen. These microorganisms mine iron and sulfur from the pyrite to build biocatalysts needed for growth. The results have potential applications in biotechnology.
Registration is now open for Lawrence Livermore National Laboratory’s (LLNL’s) summer science education programs. Summer programming includes opportunities for both teachers and students.
Cameras that can scan an entire body in a fraction of a second can give spinal surgeons an accurate assessment of how much range of motion youth with scoliosis have in their torso – a critical piece of information for guiding management of people with the condition, researchers at Hospital for Special Surgery (HSS) in New York City have found.
Reducing the methylation of a key messenger RNA can promote migration of macrophages into the brain and ameliorate symptoms of Alzheimer’s disease in a mouse model, according to a new study publishing March 7th in the open access journal PLOS Biology by Rui Zhang of Air Force Medical University in Xian, Shaanxi, China. The results illuminate one pathway for entrance of peripheral immune cells into the brain, and may provide a new target for treatment of Alzheimer’s disease.
Love muffins? We’re talking about a tasty, fluffy muffin that has no artificial additives and that simultaneously contains lots of beneficial nutrients.
The Regenerative Medicine Hub continues to grow and attract top talent with the addition of Ron Hann, PhD, a former senior level official with the Department of Defense.
Dr. Sang Kyung Kim (Director) and Dr. Seungwon Jung’s research team at the Center for Augmented Safety System with Intelligence, Sensing of the Korea Institute of Science and Technology (KIST, President: Seok Jin Yoon) announced that they had developed an ultrafast PCR technology.
The Korea Institute of Machinery and Materials (President Park Sang-jin, hereinafter referred to as KIMM), an institution under the jurisdiction of the Ministry of Science and ICT, has succeeded in developing a smart, customizable prosthetic socket that automatically fills the socket with air upon detecting the empty space inside of the socket in real time based on artificial intelligence.
A research team led by Dr. Ho Sang Jung of the Surface & Nano Materials Divison of the Korea Institute of Materials Science (KIMS), a government-funded research institute under the Ministry of Science and ICT, conducted joint research with Professor Junsuk Rho of POSTECH and Professor Samjin Choi of Kyung Hee University Medical School to find metabolites in urine. They succeeded in developing a strip-type urine sensor that can amplify the light signal of metabolites in urine and in diagnosing cancer in the field.
Scientists at the University of Sussex have successfully trialed new biodegradable health sensors that could change the way we experience personal healthcare and fitness monitoring technology.
The discovery of a strain of bacteria shown to reduce inflammation in the intestine caused by irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) could bring relief to millions of sufferers after being turned into an innovative natural food supplement by University of Bristol biotech spin-out Ferryx.
Zhang et al. identified an epitranscriptomic mechanism regulating cortical neural stem cells in the embryonic mouse brain and human forebrain organoids. Specifically, Mettl8 installs m3C modification on mitochondrial tRNAThr/Ser(UNC), which regulate
Cortical damage is irreparable and poses a challenge to regenerative medicine. Whether brain organoids can compensate for injured brain regions remains unclear. In this issue of Cell Stem Cell, Jgamadze et al. report that human forebrain organoids t
In vitro models to study human somitogenesis, the formation of the segmented body plan, have so far been limited.1 Two papers in Nature now report the creation of pluripotent stem cell (PSC)-derived 3D culture systems that recapitulate the formation
Song et al. (Nature Methods, 2022) engineered a 3D model of the human outer blood-retina barrier (oBRB) that recapitulates key features of healthy and age-related macular degeneration (AMD)-affected eyes.1 We shine a spotlight on this tissue-enginee
The generation of off-the-shelf CAR-T cells from TiPSCs has been hindered by the difficulty to recapitulate adaptive T cell development and lower therapeutic efficacy compared to peripheral blood CAR-T cells. Ueda et al. address these issues in a t
In this issue, Wells et al. combine genetic multiplexing (“village-in-a-dish”) and Stem-cell-derived NGN2-accelerated Progenitors (SNaPs) to evaluate genotype-phenotype relationships across 100 donors in the context of Zika virus infection in th
The time has come to create a new kind of computer, say researchers from John Hopkins University together with Dr Brett Kagan, chief scientist at Cortical Labs in Melbourne, who recently led development of the DishBrain project, in which human cells in a petri dish learnt to play Pong.
UC San Diego’s new Astrobiotechnology Hub brings together leaders in academia, biotechnology and aerospace industries under a united mission to advance stem cell science and commercialization in space.
In APL Bioengineering, researchers describe how gut-on-a-chip devices can bridge lab models and human biology. Modeling the microbiome is particularly difficult because of its unique environmental conditions, but through creative design, gut-on-a-chip devices can simulate many of these properties, such as the gut’s anaerobic atmosphere, fluid flow, and pulses of contraction/relaxation. Growing intestinal cells in this environment means that they more closely resemble human biology compared to standard laboratory cell cultures.
Scientists have shown that the biomass of 12 previously unstudied strains of cyanobacteria from around the globe is efficient at the biosorption of the rare earth elements lanthanum, cerium, neodymium, and terbium from aqueous solutions. This allows these rare elements, for which demand is steadily growing, to be collected from wastewater from mining, metallurgy, and the recycling of e-waste and reused.
Researchers from the University of Technology Sydney have developed a new device that can detect and analyse cancer cells from blood samples, enabling doctors to avoid invasive biopsy surgeries, and to monitor treatment progress.
Diseases caused by ischemia are one of the leading causes of death in the world. Current therapies for treating acute myocardial infarction, ischemic stroke, and critical limb ischemia do not complete recovery. Regenerative therapies opens new
Researchers from the Organoid group (former Clevers group, Hubrecht Institute) together with researchers from the Princess Máxima Center for pediatric oncology established novel human organoid models of fatty liver disease.
Northwestern University researchers have developed a first-of-its-kind small, flexible, stretchable bandage that accelerates healing by delivering electrotherapy directly to the wound site.
Thrive Bioscience Inc., an innovative provider of automated live cell imaging instruments and software, debuts a new integrated suite of unique and exciting capabilities that significantly advance the field of live cell imaging.