Feature Channels: Blood

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The first clinical study investigating the use of the direct oral anticoagulant, rivaroxaban, to prevent blood clots in patients with cancer at high-risk published today in the New England Journal of Medicine. The study found no significant reduction in venous thromboembolism or death in the overall 180-day trial period; however, the researchers did observe a lower incidence of these events while patients were actively on the study drug, or during the on-treatment period.

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EMBARGOED: A new study has identified a drug that potentially could make a common type of immunotherapy for cancer even more effective. The study in laboratory mice found that the drug dasatinib, which is FDA-approved to treat certain types of leukemia, greatly enhances responses to a form of immunotherapy that is used against a wide range of other cancers.

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The Children’s Hospital University of Illinois will host an annual head-shaving event to raise money for the St. Baldrick’s Foundation on Feb. 22.

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A new study published in the Journal of Gerontology Series A has found that eating 200g of blueberries every day for a month can lead to an improvement in blood vessel function and a decrease in systolic blood pressure in healthy people.

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Healthy white blood cells, called “T-cells,” play a crucial role in how the body fights follicular lymphoma. That's according to the results of a study led by Mayo Clinic hematologists Zhi Zhang Yang, M.D., and Stephen Ansell, M.D., Ph.D., that was published in Cell Reports. T-cells are a key part of the immune system and protect the body by fighting infections and cancer.

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Study: Adolescent Female Blood Donors At Risk For Iron Deficiency And Associated Anemia 02/19/2019 AddThis Sharing Buttons Share to Facebook Share to TwitterShare to EmailShare to PrintShare to More New public health measures could help protect this vulnerable population, authors say Credit: iStock Female adolescent blood donors are more likely to have low iron stores and iron deficiency anemia than adult female blood donors and nondonors, which could have significant negative consequences on their developing brains, a new study led by Johns Hopkins researchers suggests. Based on these findings, the authors propose a variety of measures that could help this vulnerable population.

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Cancer clinical trials are an important option for patients with cancer. Yet, once a trial ends, patients still need care plans. Little is known at what point during clinical trial transitions to initiate advance planning discussions or how to educate research teams to communicate with and prepare patient-participants and their families for the next steps after they leave a cancer clinical trial.

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Scientists have discovered new ways in which the body regulates blood clots, in a discovery which could one day lead to the development of better treatments that could help prevent and treat conditions including heart diseases, stroke and vascular dementia.

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Collectively, assessing a snapshot of a person’s unique state of immune health is called immune profiling, which can entail identifying immune-cell-associated genes and proteins, as well as the cell types themselves.

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St. Jude Children’s Research Hospital scientists have completed one of the largest studies yet designed to advance understanding of why Hispanic children are more likely to develop leukemia and less likely to survive

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As Valentine’s Day arrives, there’s no doubt love is once again in the air during this annual holiday that dates as far back as the 14th century. So, what exactly does it feel like to fall in love and how does love affect us as humans? Many scientists have proven falling in love has its physical benefits on both men and women, but can falling in love influence the immune system in women?

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A new reversible, drug-free antiplatelet therapy could reduce the risk of blood clots and potentially prevent cancer metastasis, according to a study published today in Science Translational Medicine.

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St. Jude Children’s Research Hospital has been named a recipient of Microsoft Corp.’s 2019 Health Innovation Award for the St. Jude Cloud, a data-sharing resource for the global research community that gives scientists immediate access to genomics data that previously could take weeks to download.

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A new tool from the Keck School of Medicine of USC can improve development and effectiveness of leading-edge cancer therapies derived from patients’ immune systems.

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USC Norris Comprehensive Cancer Center names Caryn Lerman as new director to bolster interdisciplinary science and leverage the cancer center’s entrepreneurial spirit

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UCLA researchers have found that people involved in electric scooter accidents are sometimes injured badly enough — from fractures, dislocated joints and head injuries — to require treatment in an emergency department. The researchers examined data from 249 people who were treated at the emergency departments of UCLA Medical Center, Santa Monica, and Ronald Reagan UCLA Medical Center between Sept.

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Keck Medicine of USC announces the acquisition of Los Angeles Cardiology Associates, a cardiovascular care group with eight locations across the Los Angeles region.

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By discovering the culprit behind decreased blood flow in the brain of people with Alzheimer’s, biomedical engineers at Cornell University have made possible promising new therapies for the disease.

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A detailed analysis of blood samples from Ebola patients is providing clues about the progression of the effects of the virus in patients and potential treatment pathways. The findings point to a critical role for a molecular pathway that relies on the common nutrient choline, as well as the importance of cellular bodies known as microvesicles.

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New insights on circumventing a key obstacle on the road to anti-scarring treatment have been published by Maksim Plikus, an associate professor in development and cell biology at the UCI School of Biological Sciences and colleagues in Nature Communications. The research team discovered that the natural scar-free skin repair process relies partially on assistance from circulating blood cells. The results point the way toward possible treatments for scar-free wound healing that target the body’s own blood cells.

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A simple puff into a handheld device may one day be all it takes for people with diabetes to monitor their blood sugar

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A new UCLA-led study shows that men with low- or intermediate-risk prostate cancer can safely undergo higher doses of radiation over a significantly shorter period of time and still have the same, successful outcomes as from a much longer course of treatment.

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An individualized diet based on a person's genetics, microbiome and lifestyle is more effective in controlling blood glucose (sugar) levels than one that considers only nutritional composition of food, Mayo Clinic researchers have confirmed. The research published in the Feb. 8 edition of JAMA Network Open demonstrates that each person's body responds differently to similar foods, due to the unique composition of each person's gut microbiome — the complex community of trillions of bacteria within the digestive track.

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A Rutgers-led team has discovered two genes that make some strains of harmful Staphyloccocus bacteria resistant to treatment by copper, a potent and frequently used antibacterial agent. The discovery shows that Staphyloccocus aureus can acquire additional genes that promote infections and antibacterial resistance and may open new paths for the development of antibacterial drugs, according to a study in the Journal of Biological Chemistry.

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Blood cells could hold the key to aging, according to new research out of Case Western Reserve University School of Medicine. In a study published in Aging Cell, researchers found human blood cells have an intrinsic clock that remains steady even after transplant. The researchers say the clock could control human aging and may underlie blood cancers.

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Researchers at the University of Michigan Rogel Cancer Center have cataloged circular RNA in multiple cancers and conducted initial research that suggests these stable structures could serve as cancer biomarkers in blood or urine.

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New findings published in “Nature Communications” could apply to the manufacture of self-assembling nanomaterials and the creation of environmentally responsive sensors. This could lead to new methods for making nanoscale devices and more economical medical, point-of-care diagnostics.

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System-based intervention can eliminate racial disparities in lung cancer treatment, which before the three-part intervention were 78 percent for white patients, 69 percent for black patients. With the intervention, treatment rates were 95 percent for white patients, 96.5 percent for black patients.

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To make it easier for patients to receive world-class cancer care, UC San Diego Health has added a new multidisciplinary cancer clinic in Hillcrest and expanded its infusion center for both oncology patients and others in need of infusion services.

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Wolters Kluwer, Health announced today that the Journal of Psychosocial Oncology Research & Practice, the newest journal of the International Psycho-Oncology Society (IPOS), will be published under the Lippincott portfolio.

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The National Comprehensive Cancer Network® (NCCN®) announces formal endorsements from the governments of Ethiopia, Nigeria, and Tanzania for the NCCN Harmonized Guidelines™ for Sub-Saharan Africa, while joining cancer leaders across the globe to raise awareness and take action for World Cancer Day on February 4.

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The American Thoracic Society has developed a new clinical practice guideline for home oxygen therapy for children. The guideline appears in the Feb. 1 edition of the Society’s American Journal of Respiratory and Critical Care Medicine.

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An expert panel assembled by the College of American Pathologists (CAP) is developing an evidence-based clinical practice guideline that aims to reduce variability, identify optimal testing, and improve the accurate diagnosis of patients with monoclonal gammopathies (MGs).

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Extremely high blood pressure that leads to strokes, heart attacks and acute kidney damage, classified as hypertensive emergency, is five times higher in inner-city African-American patients than the national average, according to a recent study co-lead by a Rutgers researcher.

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New experimental cancer treatments are raising hopes among clinicians and patients for longer survival times and cures. But clinical trials that test such treatments also need to analyze the impact on patients of potentially harsh side effects, known as adverse events. A major new study now underway aims to better incorporate patient feedback into clinical trials that help determine which new cancer treatments will be approved for use.

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During cancer immunotherapy, immune cells often undergo a form of cellular suicide, termed apoptosis, which can limit the therapy’s effectiveness.

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The National Comprehensive Cancer Network® (NCCN®) has published updated resources for improving and facilitating quality, effective, efficient, and accessible cancer care in the Middle East and North Africa (MENA).

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Patients whose own red blood cells are recycled and given back to them during heart surgery may experience shorter hospital stays and fewer complications than patients who receive donated blood.

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Intensive control of blood pressure in older people significantly reduced the risk of developing mild cognitive impairment (MCI), a precursor of early dementia, in a clinical trial led by scientists at Wake Forest School of Medicine, part of Wake Forest Baptist Health.

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A team of Vanderbilt University Medical Center researchers, working with the U.S. Department of Veteran’s Affairs (VA), has discovered genetic associations with blood pressure that could guide future treatments for patients with hypertension.

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In an article recently published in JCI Insight, researchers from the University of Alabama at Birmingham and Vanderbilt University have identified checkpoint inhibitor resistance mechanisms in many solid tumor cancers, including melanoma, lung cancer and breast cancer.

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Intermountain Healthcare Precision Genomics has developed a new gene panel that will provide clinical utility to classify and diagnose certain types of blood cancers.

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A simple blood test reliably detects signs of brain damage in people on the path to developing Alzheimer’s disease – even before they show signs of confusion and memory loss, according to a new study from Washington University School of Medicine in St. Louis and the German Center for Neurodegenerative Diseases.

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Study led by St. Jude Children’s Research Hospital found treatment guided by measuring minimal residual disease was associated with better outcomes for hypodiploid acute lymphoblastic leukemia patients

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A mechanism which drives leukaemia cell growth has been discovered by researchers at the University of Sussex, who believe their findings could help to inform new strategies when it comes to treating the cancer.

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Lifestyle and health factors that are good for your heart can also prevent diabetes, according to a new study by researchers at The Ohio State University College of Medicine.

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“Our aim,” the authors write, “is therefore to use our collective experiences and knowledge to highlight how the current debate about gene drives could benefit from lessons learned from other contexts and sound communication approaches involving multiple actors.”

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More than 90 percent of B-ALL cases can now be classified by subtype, up from 70 percent several years ago. The number of proposed B-ALL subtypes is now 23.