Based on a novel approach to drug discovery, researchers at Georgetown Lombardi Comprehensive Cancer Center say an agent approved to treat a type of leukemia might also help young people with a much rarer and aggressive form of cancer, Ewing sarcoma.
The 2018 Experimental Biology meeting will be held April 21-25 in San Diego. With more than 14,000 attendees and hundreds of scientific sessions, EB 2018 is a life science research bonanza you won’t want to miss.
Younger patients with severe coronary artery disease may experience better long-term outcomes when they are treated with coronary artery bypass grafting (CABG) instead of more popular and less invasive stenting procedures.
An experienced interdisciplinary team of psoriasis and computational researchers from Case Western Reserve University School of Medicine (CWRU SOM) and University Hospitals Cleveland Medical Center (UHCMC) has received a $6.5M, 5-year grant from the National Institute of Arthritis, Musculoskeletal and Skin Diseases (NIAMS). The grant supports a Center of Research Translation in Psoriasis (CORT) at CWRU and UHCMC.
The Cardiovascular Research Foundation (CRF) is pleased to announce that the latest issue of Structural Heart: The Journal of the Heart Team is now available online.
The Transplant Institute at NYU Langone Health launches new lung transplant program.
A specialized stenting system used to open blocked arteries in the brain resulted in a low complication rate among a specific group of patients with stroke histories, a study led by Cedars-Sinai researchers has found. The Wingspan® Stent System Post-Market Surveillance Study (WEAVE™) trial examined patients with a narrowing of the arteries in the brain, called intracranial stenosis, resulting from a buildup and hardening of fatty deposits called cholesterol plaque. The condition can lead to strokes.
Programmatic advances in 2017 propel graduate education offered at the only university-level academic medical center in Monmouth County, NJ.
A diet created by researchers at Rush University Medical Center may help substantially slow cognitive decline in stroke survivors, according to preliminary research presented on Jan. 25, at the American Stroke Association’s International Stroke Conference 2018 in Los Angeles. The finding are significant because stroke survivors are twice as likely to develop dementia compared to the general population.
Houston Methodist Hospital performed its 1000th heart transplant. The hospital's first was performed by Dr. Michael DeBakey in 1968 as part of the world's first multi-organ transplant. The patient is a 23-year old man who suffers from Becker's Muscular Dystrophy, a rare form of the disease that damages the heart.
A review of more than 80 studies reveals that changes in the immune cells of people with human immunodeficiency virus (HIV) infection may increase their risk of cardiovascular disease (CVD).
A new study shows that binge drinkers have increased levels of a biomarker molecule — microRNA-21 — that may contribute to poor vascular function. Researchers believe that measurements of microRNA-21 could help determine if a patient with a history of binge drinking is at risk of developing cardiovascular disease.
NYU Langone Hospital – Brooklyn has appointed four highly skilled heart specialists to integrate new technology and advances in research with the care delivered in the community.
Billions of US taxpayer dollars have been invested in Africa over the past 15 years to improve care for millions suffering from the HIV/AIDS epidemic; yet health systems on the continent continue to struggle. What if the investments and lessons learned from HIV could be used to improve care for those with other serious chronic conditions? With this question in mind, researchers from Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center, along with investigators and clinicians based in Uganda, borrowed an HIV/AIDS innovation to seek inroads against rheumatic heart disease in sub-Saharan Africa.
The Society of Thoracic Surgeons (STS), the Society of Cardiovascular Anesthesiologists (SCA), and the American Society of ExtraCorporeal Technology (AmSECT) released a new clinical practice guideline that includes major recommendations for the use of blood thinning medication (anticoagulants) during heart surgery.
The Cardiovascular Research Foundation (CRF) will hold a free seminar, “The Link Between Diabetes & Your Heart,” on Wednesday, February 7, 2018 in New York City. The seminar, part of a series of Mini-Med School seminars conducted by the CRF Women’s Heart Health Initiative, will focus on providing attendees a deeper understanding of diabetes and its connection with cardiovascular disease.
Doctors have long treated heart attacks, improved asthma symptoms, and cured impotence by increasing levels of a single molecule in the body: nitric oxide. The tiny molecule can change how proteins function. But new research featured in Molecular Cell suggests supplementing nitric oxide—NO—is only the first step. Researchers have discovered previously unknown enzymes in the body that convert NO into “stopgap” molecules—SNOs—that then modulate proteins. The newly discovered enzymes help NO have diverse roles in cells. They may also be prime therapeutic targets to treat a range of diseases.
People with diabetes, heart failure and other chronic diseases often live independent lives, without a traditional caregiver. But many have a family member or friend who plays a key supporting role in their health care.
A longtime blood test that measures the likelihood of a cardiac event has become more sensitive and more precise. Why doctors and patients should be cautiously optimistic.
A rare glimpse into the prior authorization requirements implemented by public and private insurance providers across the country has found substantial administrative burden for a new class of medications for patients with high cholesterol that places them at high risk for heart attack or stroke. So-called proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are self-injected medications approved for individuals with a genetic condition called familial hypercholesterolemia (FH) and those with atherosclerotic cardiovascular disease (ASCVD) who have high cholesterol despite receiving traditional statin medications and other treatments. Results of the study are published in Circulation: Cardiovascular Quality and Outcomes.
Large, human cardiac-muscle patches created in the lab have been tested, for the first time, on large animals in a heart attack model. This clinically relevant approach showed that the patches significantly improved recovery from heart attack injury.
“Decorating” cardiac stem cells with platelet nanovesicles can increase the stem cells’ ability to find and remain at the site of heart attack injury and enhance their effectiveness in treatment.
One of the NIH’s training awards, the highly selective Kirschstein fellowship is conferred to top U.S. graduate students in health science-related fields.
While refining ways to grow arterial endothelial cells in the lab, a regenerative biology team at the Morgridge Institute for Research at the University of Wisconsin-Madison unexpectedly unearthed a powerful new model for studying a hallmark of vascular disease.
According to new research in the American Heart Association journal, Circulation: Cardiovascular Quality and Outcomes, almost 5 percent of heart failure risk was connected to neighborhood factors.
Jacobs Medical Center at UC San Diego Health in La Jolla recently received certification from the Joint Commission to be a Comprehensive Stroke Center. This certification is in addition to the existing accreditation at UC San Diego Medical Center in Hillcrest. This expansion makes UC San Diego Health the only health system in San Diego County to have two access points for comprehensive stroke care.
Exercise can reverse damage to sedentary, aging hearts and help prevent risk of future heart failure – if it’s enough exercise, and if it’s begun in time, according to a new study by cardiologists at UT Southwestern and Texas Health Resources.
An international team of researchers led from Karolinska Institutet have, in experiments on mice, pinpointed a mechanism for the conversion of energy-storing white fat into energy-expending brown fat. The study is published in the Journal of Experimental Medicine.
Your Disease Risk measures an individual's risk of 12 common cancers and five major chronic diseases. The tool, developed by researchers at Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis, incorporates the latest scientific evidence on disease risk.
Credentialed press representatives are invited to attend The Society of Thoracic Surgeons 54th Annual Meeting and Exhibition, which will include late-breaking scientific research, thought-provoking lectures, cutting-edge technologies, and innovative cardiothoracic surgery products.
For the first time, UNC School of Medicine scientists and collaborators solved the crystal structure of the activated kappa opioid receptor bound to a morphine derivative. They then created a new drug-like compound that activates only that receptor, a key step in the development of new pain meds.
On Jan. 1, Medicare began covering a new noninvasive test for heart disease called FFR-CT. "Medicare coverage is a major milestone," said Loyola Medicine cardiologist Mark Rabbat, MD. "Millions of Americans now can potentially benefit from this game-changing technology."
Jonathan A. Epstein, MD, executive vice dean and chief scientific officer of Penn Medicine, has received a National Heart, Lung, and Blood Institute (NHLBI) Outstanding Investigator Award. The highly competitive award provides long-term support to “an experienced investigator with an outstanding record of research productivity.” In issuing the award, the NHLBI, which is part of the National Institutes of Health, described Epstein as “an outstanding, pioneering investigator” and “a gold standard role model for physician-scientists in the field.”
Mayo Clinic researchers show that hysterectomy with ovarian conservation is associated with a significantly increased risk of several cardiovascular diseases and metabolic conditions. The findings are published in Menopause.
Recently, researchers have been studying diseases with a new approach: small, organ-on-a-chip devices that mimic the functions of human organs, serving as potentially cheaper and more effective tools. Now researchers have built a device that's especially good for modeling atherosclerosis. In this week’s APL Bioengineering, researchers illustrate how the new device can be used to study important inflammatory responses in cells that line the vessel in ways that could not be done in animal models.
In a direct comparison study, Johns Hopkins researchers have added to evidence that a newer method of calculating so-called “bad cholesterol” levels in the blood is more accurate than the older method in people who did not fast before blood was drawn.
The proteasome inhibitor carfilzomib has taken on an increasing role in the treatment of multiple myeloma, but new research from the Abramson Cancer Center of the University of Pennsylvania shows the therapy comes with the risk of cardiovascular problems in a higher than expected percentage of patients.
Thanks, in part, to pigs at the University of Wisconsin–Madison’s Arlington Agricultural Research Station, scientists now are catching up on understanding the roots of calcific aortic valve disease (CAVD).
The combination of a new clinical trial and tissue bank is innovating stroke care and research at the University of Kentucky. Led by a multidisciplinary team of clinicians and scientists, the studies aim to develop new treatments using existing therapies that protect brain tissue after a stroke, and to learn more about the physiology of the event.
An FDA-approved drug to treat high blood pressure seems to extend life span in worms via a cell signaling pathway that may mimic caloric restriction.
A long-term look at heart attack care and spending in America in the 21st Century shows more survival, more spending, and more variation between hospitals on both scores. And while spending on rapid angioplasty appears to be paying off, a lot of the dollars spent in the six months after a heart attack aren’t making a difference in the long-term death rate.
Varenicline, one of the most commonly prescribed drugs for helping people quit smoking, may put them at higher risk for a cardiovascular event, according to new research published online in the American Journal of Respiratory and Critical Care Medicine.
Hackensack Meridian Health Hackensack University Medical Center is among the first in the tri-state region and the first in Bergen County, New Jersey to offer an innovative new treatment that prevents stroke in patients with blocked carotid arteries, the major blood vessels that deliver blood to the brain.
The American Physiological Society (APS) is honored to announce a new $50,000 grant from The Hearst Foundations in support of the APS undergraduate summer research fellowships (UGSRF) program that will be used to fund immersive laboratory research experiences for five students.
A new video by the University of Warwick highlights a bitter side to our sugar consumption at Christmas. The short film highlights how excessive consumption of sugar can affect our health – and how the sugar trade in the past and today has caused inequality and bloodshed.Today Britons eat too much sugar, on average 10 per cent of our daily calories come from sugar which is equivalent to 60 g per day; however WHO guidelines state that adults should eat no more than of 30g of sugar a day which is just five per cent of our daily calorific intake.
Tomorrow, ministers at the 15th ministerial council meeting of the Energy Community in Kosovo will adopt new rules for emission limits for coal power plants in the Western Balkans (as part of the transposition of the EU’s Industrial Emissions Directive into national law).
A clinical decision support application developed by Intermountain Healthcare researchers that more quickly identifies when heart failure becomes advanced and a heart patient’s care needs have changed is successful in helping to improve patient’s quality of live and longevity, according to a new study.
Penn Medicine’s Innovation Accelerator Program, now in its fifth year, has announced funding for four new projects aimed at addressing disparities to improve health care delivery and patient outcomes.
Radiation therapy often is used to treat cancer patients. Now, doctors at Washington University School of Medicine in St. Louis have shown that radiation therapy — aimed directly at the heart — can be used to treat patients with a life-threatening heart rhythm. They treated five patients with irregular heart rhythms, called ventricular tachycardia, who had not responded to standard treatments. The therapy resulted in a dramatic reduction in the number of ventricular tachycardia episodes.
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