Feature Channels: Kidney Disease

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Newswise: UC San Diego Health Named Center of Excellence for Polycystic Kidney Disease
Released: 13-Dec-2022 12:35 PM EST
UC San Diego Health Named Center of Excellence for Polycystic Kidney Disease
UC San Diego Health

UC San Diego Health has been named a Center of Excellence for polycystic kidney disease (PKD) by the PKD Foundation – the leading advocacy group dedicated to finding treatments and a cure for PKD. UC San Diego Health is one of just 28 institutions nationwide to receive this designation.

Released: 7-Dec-2022 11:35 AM EST
Staph infection-induced kidney disease may be linked to bacterial gene mutation
Ohio State University

Researchers aiming to predict which staph-infection patients might develop a related kidney disease have found a high frequency of gene mutations in the infecting bacteria of affected patients, which suggests these variants may play a role in the body’s initiation of the renal damage.

Released: 6-Dec-2022 8:55 AM EST
Medical Students Lead Nationwide Movement to Excise Racism From Nephrology Curricula
Mount Sinai Health System

As medical schools across the country grapple with the arduous process of revising their curricula to be anti-racist, students at the Icahn School of Medicine at Mount Sinai have turned a critical eye on the very textbooks that have trained medical students for years.

29-Nov-2022 2:00 PM EST
Dapagliflozin reduces risk for hospitalization in patients with CKD with or without diabetes
American College of Physicians (ACP)

Dapagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor, reduced the risk for hospitalization for any cause in patients with chronic kidney disease (CKD) with and without type 2 diabetes.

Released: 5-Dec-2022 8:00 AM EST
Published Real World Evidence Demonstrates KidneyIntelX™ Improved Clinical Decisions and Outcomes in High-Risk Patients with Early-Stage Diabetic Kidney Disease
Mount Sinai Health System

Renalytix plc (NASDAQ: RNLX) (LSE: RENX) announces the publication of new real-world evidence (RWE) in Primary Care and Community Health demonstrating the Company’s KidneyIntelX bioprognostic™ test resulted in changed clinical decision making for patients in the early-stage of diabetic kidney disease (DKD) being cared for within the Mount Sinai Health System’s Population Health Ambulatory Pharmacy and Condition Management programs.

   
Released: 1-Dec-2022 3:10 PM EST
Kidneycure Grant Applications Now Open to Support Investigators Committed to Advancing Kidney Health
American Society of Nephrology (ASN)

KidneyCure, the grants program supported by the American Society of Nephrology (ASN) Foundation, today announced that applications for its 2023 grants programs are now open. KidneyCure grants support clinical and basic research and kidney health investigators at key professional development milestones. The submission deadline is Wednesday, December 7, 2022, at 2:00 p.m. EST. Grant applications and guidelines can be found at https://www.kidneycure.org/

Newswise: Excess Oxygen During Anesthesia Linked to Risk of Organ Injury

 
28-Nov-2022 5:10 PM EST
Excess Oxygen During Anesthesia Linked to Risk of Organ Injury  
Vanderbilt University Medical Center

Unnecessarily high concentrations of oxygen given to patients under general anesthesia may increase risk of injury to the kidneys, lungs and heart, according to a large Vanderbilt University Medical Center-led study published in The BMJ, the flagship journal of the British Medical Association.

Released: 29-Nov-2022 12:00 PM EST
For some small kidney cancers, freezing is more effective than heat treatment
Wolters Kluwer Health: Lippincott

For patients with early-stage renal cell carcinomas (RCCs) that measure between 3 and 4 centimeters, a procedure that destroys the cancer by freezing – called cryoablation – yields a lower-risk of cancer-related death compared to heat-based thermal ablation, reports a preliminary study in The Journal of Urology®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.

17-Nov-2022 4:50 PM EST
Study estimates the lifetime benefit of combination therapy in patients with kidney disease without diabetes
American Society of Nephrology (ASN)

A recent analysis of clinical trial data estimates that treatment with the combination of angiotensin-converting enzyme inhibitors and/or angiotensin receptor blockers (ACE inhibitors/ARBs) and sodium-glucose cotransporter-2 (SGLT2) inhibitors can substantially increase the lifetime survival free of kidney failure for patients with albuminuric chronic kidney disease without diabetes.

Newswise:Video Embedded two-couples-two-kidneys-and-all-heart
VIDEO
Released: 22-Nov-2022 12:50 PM EST
Two Couples, Two Kidneys—and All Heart
Cedars-Sinai

This Thanksgiving, when the Moraleses think about what they’re thankful for, the Thompsons are at the top of the list.

Released: 21-Nov-2022 4:50 PM EST
The Polycystic Kidney Disease (PKD) Foundation Names Mount Sinai Health System Partner Clinic
Mount Sinai Health System

The polycystic kidney disease (PKD) Foundation—the only organization in the U.S. dedicated solely to finding treatments and a cure for PKD recently named Mount Sinai Health System as a PKDF Partner Clinic for their desire to support patients with Autosomal Dominant PKD (ADPKD).

Newswise: Together with Missouri S&T, Saint Louis University Researchers Use Artificial Intelligence to Improve Kidney Transplant Process
Released: 21-Nov-2022 2:30 PM EST
Together with Missouri S&T, Saint Louis University Researchers Use Artificial Intelligence to Improve Kidney Transplant Process
Saint Louis University

With a new grant that brings together engineering expertise from Missouri S&T and medical expertise from Saint Louis University’s School of Medicine, researchers are investigating how artificial intelligence can support matchmaking between donated kidneys and transplant centers to help more patients in need.

Newswise: Podocyte Protectors: NIH Awards CHLA’s GOFARR Laboratory Additional Grants to Combat Chronic Childhood Kidney Disease
Released: 18-Nov-2022 8:05 AM EST
Podocyte Protectors: NIH Awards CHLA’s GOFARR Laboratory Additional Grants to Combat Chronic Childhood Kidney Disease
Children's Hospital Los Angeles

CHLA has received a new five-year award of $3.2 million from the National Institutes of Health (NIH) to research the underlying mechanisms that lead to kidney failure and to develop new treatments to protect kidney function.

Newswise: Albert Einstein College of Medicine Receives $6.6M in NIH Grants to Lead New York Consortium for Kidney, Urological, and Hematological Research and Training
Released: 16-Nov-2022 11:00 AM EST
Albert Einstein College of Medicine Receives $6.6M in NIH Grants to Lead New York Consortium for Kidney, Urological, and Hematological Research and Training
Albert Einstein College of Medicine

The National Institutes of Health has awarded Albert Einstein College of Medicine a five-year, $6.6 million grant to lead a New York-based consortium of medical schools to train young scientists in kidney, urology, and hematology research.

Released: 11-Nov-2022 5:30 PM EST
Study assesses environmental sustainability practices in dialysis facilities
American Society of Nephrology (ASN)

Survey results from dialysis facilities in Australia and New Zealand indicate that environmental sustainability is not currently prioritized in facilities’ clinical practice, building design, or infrastructure and management systems.

Newswise:Video Embedded diabetes-awareness-month
VIDEO
Released: 10-Nov-2022 5:10 PM EST
Diabetes Awareness Month
Cedars-Sinai

Diabetes is a chronic health condition that impacts how the body turns food into energy. More than 37 million people in the United States have Type 2 diabetes, the most common form of the metabolic disorder, according to the Centers for Disease Control and Prevention. An additional 96 million adults have prediabetes and most of them are unaware they are developing a serious chronic disease.

7-Nov-2022 10:20 AM EST
Study examines symptom burden before and after starting dialysis in older adults
American Society of Nephrology (ASN)

Older adults with kidney failure in Europe experienced a considerable increase in symptom burden in the year before starting dialysis, which stabilized in the year after dialysis initiation.

Released: 9-Nov-2022 3:15 PM EST
Knowledge is power. The latest research on arthritis is right at your fingertips
Newswise

Here are some of the latest articles that have been added to the Arthritis channel on Newswise.

3-Nov-2022 1:05 PM EDT
Protected From a Form of Cell Death, Women are More Resilient to Kidney Disease
Duke Health

In the battle of the sexes, women beat men in their ability to recover from kidney injury, but the reasons are not well understood. A study led by Duke Health researchers provides some insights: Females, it turns out, have an advantage at the molecular level that protects them from a form of cell death that occurs in injured kidneys. This protection could be exploited as a potential therapeutic.

Released: 8-Nov-2022 10:20 AM EST
Somatus First Kidney Care Company to Achieve Certification for Claim of Improved Patient Outcomes from Validation Institute
Somatus

Somatus, the nation's leading and largest value-based kidney care company, has received a 2022 Validation Program Report certifying the claim that kidney disease patients who receive Somatus Transition of Care Assessment (TCA) services have fewer hospital readmissions than similar patients who do not receive TCA services.

2-Nov-2022 9:45 AM EDT
Michelle A. Josephson, MD, FASN, to Become Next President of the American Society of Nephrology
American Society of Nephrology (ASN)

The American Society of Nephrology (ASN) is pleased to announce that Michelle A. Josephson, MD, FASN, will become the society’s next president. Dr. Josephson, who succeeds Susan E. Quaggin, MD, FASN, will assume her new role on January 1, 2023.

31-Oct-2022 10:05 AM EDT
Strategy Suggests Combining Surrogate Markers for Kidney Disease Progression in Clinical Trials
American Society of Nephrology (ASN)

In clinical trials of patients with chronic kidney disease, combining information from the treatment effects on two markers of kidney disease progression—urinary albumin:creatinine ratio change and glomerular filtration rate slope—improves predictions of treatment effects on clinical endpoints.

31-Oct-2022 10:05 AM EDT
Conservative management vs. dialysis for preventing hospitalizations in patients with advanced kidney diseases and different ethnicities
American Society of Nephrology (ASN)

Researchers have compared the impact of conservative management vs. dialysis on hospitalization outcomes in patients with advanced kidney disease across different races/ethnicities.

31-Oct-2022 10:05 AM EDT
Did having kidney disease and other conditions affect COVID-19 outcomes in different waves of the pandemic?
American Society of Nephrology (ASN)

During 4 waves of the COVID-19 pandemic in New York City, the risk of severe COVID-19 was associated with pre-existing chronic kidney disease, as well as heart disease, diabetes, and hypertension.

31-Oct-2022 10:05 AM EDT
The COVID-19 pandemic has had direct and indirect impacts on the mortality of patients on dialysis
American Society of Nephrology (ASN)

During the COVID-19 pandemic in 2020, mortality risk for both COVID-19–positive and other patients on hemodialysis fluctuated in line with two waves of the pandemic in the general population.

31-Oct-2022 10:05 AM EDT
Risks of kidney failure and death differ in Black and white veterans over time after chronic kidney disease onset
American Society of Nephrology (ASN)

Among US veterans with chronic kidney disease (CKD), Black individuals had a higher risk of developing kidney failure compared with White veterans, and their risk was more pronounced in the early years after kidney disease onset.

31-Oct-2022 10:05 AM EDT
Long-Term Exposure to Air Pollution May Increase Kidney Disease Risk
American Society of Nephrology (ASN)

Among adults with normal kidney function, exposure to higher concentrations of components of air pollution was linked with higher risks of later developing chronic kidney disease.

Released: 4-Nov-2022 10:55 AM EDT
Exploring How Diethylene Glycol Poisons the Kidney and the Combined Effects of St. John's Wort and Acetaminophen on the Liver
Society of Toxicology

A ToxSpotlight article in the November 2022 issue of ToxSci assesses the mechanism for cellular accumulation of diglycolic acid while another explores the effect of long-term St. John’s wort administration on acetaminophen-induced acute hepatotoxicity and the involved mechanisms.

2-Nov-2022 9:45 AM EDT
High-Impact Clinical Trials Yield Results that Could Improve Kidney Care
American Society of Nephrology (ASN)

The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented in-person and online at ASN Kidney Week 2022 November 3–November 6.

28-Oct-2022 3:15 PM EDT
Population-Level Study Provides Reassuring Data on the Risk of Kidney Disease Relapse After COVID-19 Vaccination
American Society of Nephrology (ASN)

• In a population-level study of 1,105 adults with stable glomerular disease (a type of autoimmune kidney disease), a first dose of a COVID-19 vaccine was not associated with relapse risk; however, receiving a subsequent vaccine dose was associated with a 2-fold higher relative risk of relapse. • Importantly, the increase in absolute risk associated with vaccination was low (1–5% depending on type of glomerular disease), and most vaccine-associated disease flares were mild.

31-Oct-2022 10:05 AM EDT
Artificial Intelligence–Based Model Predicts Patients’ Risk of Acute Kidney Injury
American Society of Nephrology (ASN)

Investigators recently developed and validated an artificial intelligence–based model that can help clinicians predict which patients in the intensive care unit are most likely to develop acute kidney injury.

31-Oct-2022 10:05 AM EDT
Researchers Develop and Test Risk Score for Childhood Kidney Condition
American Society of Nephrology (ASN)

Scientists have generated a polygenic risk score for pediatric steroid sensitive nephrotic syndrome, a kidney disease in children.

31-Oct-2022 10:05 AM EDT
Analysis Links Impaired Kidney Function with Cognitive Disorders
American Society of Nephrology (ASN)

In an analysis of data from the Framingham Heart Study, albuminuria (a marker of kidney disease) was associated with signs of silent stroke, and patients with albuminuria had a higher risk of developing mild cognitive impairment or dementia.

31-Oct-2022 10:05 AM EDT
Artificial intelligence–based algorithm predicts major adverse kidney events after hospitalization
American Society of Nephrology (ASN)

Researchers have developed and validated an artificial intelligence–based algorithm to predict hospitalized patients’ risk of major adverse kidney events after discharge.

Newswise: Ochsner Pharmacist Makes Case for Reducing Use of Broad-Spectrum Antibiotics for Acute Kidney Infections
Released: 2-Nov-2022 5:40 PM EDT
Ochsner Pharmacist Makes Case for Reducing Use of Broad-Spectrum Antibiotics for Acute Kidney Infections
Ochsner Health

A new study led by Ochsner infectious diseases clinical pharmacist Kevin Lin, PharmD, was recently published in PLoS One, suggesting that oral cephalosporins are as safe and effective as the standard of care fluoroquinolones (FQs) for the treatment of acute kidney infections.

31-Oct-2022 7:05 AM EDT
Dapagliflozin Is Not Only Clinically Effective, but Also Cost Effective in Patients with Chronic Kidney Disease
American Society of Nephrology (ASN)

A recent analysis indicates that dapagliflozin is a cost-effective treatment in patients with chronic kidney disease in addition to standard of care.

Released: 2-Nov-2022 11:30 AM EDT
American College of Rheumatology Educating Dermatologists and Nephrologists on Lupus Clinical Trials Racial Disparities
American College of Rheumatology (ACR)

The American College of Rheumatology (ACR) has released Continuing Medical Education (CME) for dermatologists and nephrologists to help them learn more about clinical trials for lupus patients in their treatment areas and the importance of getting more of African American/Black patients enrolled.

25-Oct-2022 2:05 PM EDT
Ticagrelor–aspirin antiplatelet therapy more beneficial in persons with normal renal function
American College of Physicians (ACP)

An analysis of the CHANCE-2 trial has found that persons with normal renal function receive greater benefit from antiplatelet therapy with ticagrelor–aspirin versus clopidogrel–aspirin. The analysis is published in Annals of Internal Medicine.

Released: 31-Oct-2022 4:05 PM EDT
American Society of Nephrology Commends Congressional Recognition of the 50th Anniversary of the Medicare End-Stage Renal Disease Program
American Society of Nephrology (ASN)

● The Congressional Kidney Caucus recognizes the 50th anniversary of the Medicare End-Stage Renal Disease (ESRD) Program. ● Kidney health leaders join the Congressional Kidney Caucus in calling for greater emphasis on intervening earlier and increasing disease awareness, increasing access to transplantation, and accelerating innovation in kidney health in the future of the ESRD Program.

Newswise: New Onset Chronic Kidney Disease in People with Diabetes Highest Among Ethnic, Racial Minorities
Released: 31-Oct-2022 6:00 AM EDT
New Onset Chronic Kidney Disease in People with Diabetes Highest Among Ethnic, Racial Minorities
University of California, Los Angeles (UCLA), Health Sciences

New onset chronic kidney disease (CKD) in people with diabetes is highest among racial and ethnic minority groups compared with white persons, a UCLA-Providence study finds. The study, published as a letter to the editor in the New England Journal of Medicine, found that new onset CKD rates were higher by approximately 60%, 40%, 33%, and 25% in the Native Hawaiian/Pacific Islander, Black, American Indian/Alaska Native, and Hispanic/Latino populations, respectively, compared to white persons with diabetes.

24-Oct-2022 11:25 AM EDT
Study assesses symptom trajectories and outcomes in patients with kidney disease
American Society of Nephrology (ASN)

● Among individuals with varying levels of chronic kidney disease who were not on dialysis, the prevalence of individual symptoms ranged from 24% (chest pain) to 83% (fatigue), and 98% of participants reported at least one symptom. ● Patients categorized as having a “Worse symptom score and worsening trajectory” of symptoms had higher risks of later needing dialysis and of dying before dialysis initiation.

Newswise:Video Embedded kidney-week-2022-the-world-s-premier-kidney-meeting-to-connect-people-from-across-the-globe
VIDEO
Released: 27-Oct-2022 8:05 AM EDT
Kidney Week 2022—the World’s Premier Kidney Meeting—to Connect People From Across the Globe
American Society of Nephrology (ASN)

The American Society of Nephrology (ASN) will hold Kidney Week, the world’s premier kidney meeting, in Orlando, FL, November 3–6, 2022. The results of scientific studies and high-impact clinical trials that will advance kidney-related research and medical care will be presented in-person and online.

24-Oct-2022 10:05 AM EDT
How do Canadians feel about new law that assumes consent for deceased organ donation?
American Society of Nephrology (ASN)

In 2019, two Canadian provinces passed deemed consent legislation, where adults are automatically presumed to consent to organ donation upon their death unless they registered to opt out.

Released: 25-Oct-2022 3:10 PM EDT
New Drug Is Found Effective for Treating Complicated Urinary Tract Infections
Rutgers University-New Brunswick

An international study led by a Rutgers scientist comparing new and older treatments against complicated urinary tract infections has found a new drug combination to be more effective, especially against stubborn, drug-resistant infections.

Released: 24-Oct-2022 2:05 PM EDT
Study Sheds Light on the Development of Inflammation, High Blood Pressure and Resulting Kidney Damage
Vanderbilt University Medical Center

Researchers at Vanderbilt University Medical Center have found that the change in a single letter of the genetic code promotes, in a mouse model, the development of inflammation, high blood pressure and resulting kidney damage.

Newswise: Alcoholic Pancreatitis Patients with Continued Alcohol Intake May Finally Have Therapeutic Options
Released: 21-Oct-2022 2:50 PM EDT
Alcoholic Pancreatitis Patients with Continued Alcohol Intake May Finally Have Therapeutic Options
University of Miami Health System, Miller School of Medicine

Researchers at the Miller School are looking for solutions to the continued effects of alcohol use, its harmful impact, and treatment. Understanding the mechanisms of alcohol abuse has gained importance, especially after the COVID-19 pandemic. Higher alcohol consumption led to an increased burden of pancreatic diseases in society.

Released: 21-Oct-2022 2:25 PM EDT
Researchers Examine What Happens When Patients Can Choose Concurrent Dialysis and Hospice Care
Brigham and Women’s Hospital

Today, patients utilizing their Medicare Hospice Benefits with end-stage kidney disease (ESKD) are forced to make the traumatic choice between continuing dialysis or enrolling in hospice.

Released: 20-Oct-2022 10:35 AM EDT
Single-Port Robotic Surgery Improves Patient Ratings of Scarring After Urologic Procedures
Wolters Kluwer Health: Lippincott

The use of next-generation, single-port surgical robots leads to improved cosmetic outcomes and patient perceptions of scarring after robotic kidney, bladder, or prostate surgery, reports a study in Urology Practice®, an Official Journal of the American Urological Association (AUA).



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