'Unsung' Cells Double the Benefits of a New Osteoporosis Drug
Johns Hopkins MedicineExperiments in mice with a bone disorder similar to that in women after menopause show that a scientifically overlooked group of cells are likely crucial to the process of bone loss caused by the disorder. Their discovery not only raises the research profile of the cells, called preosteoclasts, but also explains the success and activity of an experimental osteoporosis drug with promising results in phase III clinical trials.