Feature Channels: Regenerative Medicine

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Released: 18-Mar-2020 1:05 PM EDT
How “Pioneer” Protein Turns Stem Cells into Organs
Perelman School of Medicine at the University of Pennsylvania

Early on in each cell, a critical protein known as FoxA2 simultaneously binds to both the chromosomal proteins and the DNA, opening the flood gates for gene activation, according to a new study led by researchers in the Perelman School of Medicine at the University of Pennsylvania. The discovery, published in Nature Genetics, helps untangle mysteries of how embryonic stem cells develop into organs.

Newswise: Leveraging layers for enhanced tissue repair
Released: 16-Mar-2020 12:55 PM EDT
Leveraging layers for enhanced tissue repair
National Institute of Biomedical Imaging and Bioengineering

Bioengineers have created a 3D-printed scaffold designed to regenerate complex tissues composed of multiple layers of cells with different biological and mechanical properties.

Released: 12-Mar-2020 4:25 PM EDT
Mayo Clinic research discovers how stem cells repair damage from heart attacks
Mayo Clinic

Mayo Clinic researchers have uncovered stem cell-activated mechanisms of healing after a heart attack. Stem cells restored cardiac muscle back to its condition before the heart attack, in turn providing a blueprint of how stem cells may work.

Newswise: DARPA Awards $22 Million to Create ‘Smart’ Device for Healing Large Muscle Wounds
Released: 11-Mar-2020 9:00 AM EDT
DARPA Awards $22 Million to Create ‘Smart’ Device for Healing Large Muscle Wounds
Health Sciences at the University of Pittsburgh

Researchers from seven institutions team up to create a device combining artificial intelligence, bioelectronics and regenerative medicine for regrowing muscle tissue, especially after combat injuries.

Newswise: ‘Primitive’ Stem Cells Shown to Regenerate Blood Vessels in The Eye
Released: 9-Mar-2020 9:00 AM EDT
‘Primitive’ Stem Cells Shown to Regenerate Blood Vessels in The Eye
Johns Hopkins Medicine

Johns Hopkins Medicine scientists say they have successfully turned back the biological hands of time, coaxing adult human cells in the laboratory to revert to a primitive state, and unlocking their potential to replace and repair damage to blood vessels in the retina caused by diabetes. The findings from this experimental study, they say, advance regenerative medicine techniques aimed at reversing the course of diabetic retinopathy and other blinding eye diseases.

Newswise: CAR-T immunotherapy for lymphoma studied at UNC Lineberger receives fast-track designation from FDA
Released: 9-Mar-2020 8:00 AM EDT
CAR-T immunotherapy for lymphoma studied at UNC Lineberger receives fast-track designation from FDA
University of North Carolina Health Care System

Based on proof-of-concept results from clinical trials at University of North Carolina Lineberger Comprehensive Cancer Center and Baylor College of Medicine, an investigational cellular immunotherapy for Hodgkin lymphoma has received a Regenerative Medicine Advanced Therapy designation from the U.S. Food and Drug Administration.

Released: 27-Feb-2020 11:05 AM EST
UC Santa Cruz leads collaboration to speed wound healing with a novel smart bandage
University of California, Santa Cruz

Researchers will use a combination of approaches involving bioelectronic devices, machine learning, and regenerative medicine in an effort to achieve precise control over the physiological processes involved in wound healing.

Newswise:Video Embedded mount-sinai-discovers-new-drug-combo-to-induce-high-rates-of-human-beta-cell-regeneration
9-Feb-2020 7:05 PM EST
Mount Sinai Discovers New Drug Combo to Induce High Rates of Human Beta Cell Regeneration
Mount Sinai Health System

Researchers at the Icahn School of Medicine at Mount Sinai have discovered a novel combination of two classes of drugs that, together, cause the highest rate of proliferation ever observed in adult human beta cells—the cells in the pancreas that produce insulin—without harming most other cells in the body. The result is an important step toward a diabetes treatment that restores the body’s ability to produce insulin.

Released: 12-Feb-2020 8:50 AM EST
Mayo Clinic研究发现了一种修复中枢神经系统疾病的分子开关
Mayo Clinic

Mayo Clinic研究人员发现,一种分子开关能在动物体内启动一种物质,从而修复多发性硬化症等疾病中的神经损伤。在动物模型中进行的早期研究有望推动这一已获得美国食品药品监督管理局批准的疗法,同时还可能促成治疗中枢神经系统疾病的新策略。

Newswise: Superior “Bio-Ink” for 3D Printing Pioneered
Released: 10-Feb-2020 2:05 PM EST
Superior “Bio-Ink” for 3D Printing Pioneered
Rutgers University-New Brunswick

Rutgers biomedical engineers have developed a “bio-ink” for 3D printed materials that could serve as scaffolds for growing human tissues to repair or replace damaged ones in the body. Their study was published in the journal Biointerphases.

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