Lecanemab FDA Approval: U-Mich Alzheimer's disease expert available and quote #lecanemab
Michigan Medicine - University of Michigan
A Kingston University, London study found several people with learning disabilities and autism in the Netherlands chose to die legally through euthanasia and assisted suicide due to feeling unable to cope with the world, changes around them or because they struggled to form friendships.
Regular physical activity may protect against cognitive decline as we get older, but this protective effect may be diminished for people who are not getting enough sleep, according to a new study by UCL researchers.
A cochlear signal, the exact role of which has been unclear since its discovery around 70 years ago, probably gives the brain information on whether the ear is functioning normally or not.
Nerve pathways in the spinal cord can be damaged or severed after an accident or serious injury, a condition known as paraplegia. Depending on where the injury is located, different parts of the body may be affected by deficits or paralysis.
Taking good care of your teeth may be linked to better brain health, according to a study published in the July 5, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study found that gum disease and tooth loss were linked to brain shrinkage in the hippocampus, which plays a role in memory and Alzheimer’s disease. The study does not prove that gum disease or tooth loss causes Alzheimer’s disease; it only shows an association.
Older people who have fluctuating levels of cholesterol and triglycerides may have a higher risk of Alzheimer’s disease and related dementias compared to people who have steady levels, according to new research published in the July 5, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. While the study found a link, it does not prove that fluctuating levels of cholesterol and triglycerides cause dementia.
A study of 273 people found that brain circuits associated with depression were different between people with traumatic brain injury and those without TBI.
Building on its visionary investment in Cedars-Sinai’s neurosurgery scholarship program, The Ray Charles Foundation has donated a second gift of $1 million to support critical training and research to advance the neurosciences.
Distinct, though neighboring, areas of the brain are activated when processing music and language, with specific sub-regions engaged for simple melodies versus complex melodies, and for simple versus complex sentences, according to research from UTHealth Houston.
The Icahn School of Medicine at Mount Sinai has launched the Center for Ophthalmic Artificial Intelligence and Human Health, the first of its kind in New York and one of the first in the United States.
The use of thrombolysis, medications to break up blood clots, for acute ischemic stroke reduces post-stroke disability, but it is underutilized.
Pascack Valley Medical Center achieved AHA’s Gold Plus Get With the Guidelines-Stroke quality achievement award for commitment to ensuring stroke patients receive the most appropriate treatment according to nationally recognized, research-based guidelines, ultimately leading to reduced disability.
Brain damage caused by oxygen deficiency at birth is one of the main causes of death in newborns worldwide.
A new, EMBARGOED study suggests that reactivation of an ancient retrovirus from 6 million years ago may be at least partly to blame for the aggressiveness and treatment resistance of some glioblastomas.
ILAE spoke with Action Amos about plans and strategies for improving epilepsy care across Africa. Leveraged by the Intersectoral Global Action Plan on epilepsy and other neurological disorders (IGAP), four "trendsetter" countries are taking a variety of approaches to engage governments and ensure the participation of people with epilepsy in all of their initiatives.
A recently-published study led by Prof. Einat Levy-Gigi, from Bar-Ilan University, examined for the first time the interactive effect of exposure to stress in the school setting and cognitive flexibility on the tendency to develop post-traumatic symptoms among education and teaching staff. One hundred fifty education and teaching personnel (85% women and 15% men with an average age of 43 and average teaching experience of 13 years) volunteered to participate in the study and underwent an assessment of their exposure to stress, their cognitive flexibility, their ability to cope and their level of post-traumatic symptoms.
Researchers at the University of South Australia are examining the possibility of using tabletop role-playing games (TTRPGs) such as Dungeons and Dragons to promote social growth in people who are neurodivergent or live with disability.
كانت مايو كلينك من أوائل المراكز على مستوى العالم في تنفيذ عمليات دمج الفقرات بالدعم الروبوتي وباستخدام التخدير النصفي، ما يعني أن المريض مستيقظ خلال العملية. يطلق أيضًا على عملية دمج الفقرات اسم دمج الفقرات القطني عبر الثقوب. هذه العملية هي نوع من دمج الفقرات والذي يساعد على تثبيت العمود الفقري بعد المشكلات التآكلية أو المتعلقة بالسرطان أو بعد الإصابة المتسببة في عدم استقرار الفقرات.
Mayo Clinic se encuentra entre las primeras instituciones del mundo en realizar una cirugía de fusión espinal con asistencia robótica y anestesia raquídea, lo que significa que el paciente está despierto. A esta cirugía también se la conoce como TLIF, que es la sigla en inglés para fusión intersomática lumbar transforaminal.
A Mayo Clinic é um dos primeiros centros médicos do mundo a realizar uma cirurgia de fusão espinhal, denominada TLIF, que conta com assistência robótica e anestesia raquidiana, permitindo que o paciente permaneça acordado durante a intervenção. TLIF é uma sigla em inglês que significa fusão intervertebral lombar transforaminal.
Older adults with Alzheimer disease and related dementia who were admitted to an ICU were much less likely to be discharged home and faced almost twice the risk of dying soon after discharge and within the 12 months afterward.
Announcement of contents of the July 2023 issue of Neurosurgical Focus: Video
Announcement of contents of the July 2023 issue of Neurosurgical Focus
HSS doctor/ballroom dancer discusses the many physical and psychological benefits of dancing. She provides tips to prevent injury and get the most out of the activity.
A new study led by two neurologists at the University of Miami Miller School of Medicine points to a potential novel form of Car T cellular therapy for myasthenia gravis (MG), a chronic autoimmune disorder characterized by muscle weakness. The study findings were recently published in the British journal Lancet Neurology.
Protein aggregates accumulate during aging and are linked to neurodegenerative diseases like Alzheimer’s, Parkinson’s or Huntington’s disease.
Cedars-Sinai patient care teams are preparing to offer lecanemab, a new Alzheimer’s disease treatment expected to soon receive approval from the U.S. Food and Drug Administration (FDA), to patients in the coming months.
Mild cognitive impairment, which occurs in about one in six individuals in the U.S., age 65 and older, remains substantially underdiagnosed, especially in disadvantaged populations.
The results of a clinical trial have shown that a drug commonly used for patients with bleeding disorders has the potential to be used to lessen the side effects of blood-thinning drugs for patients who have experienced a stroke.
The June 2023 issue of SLAS Discovery contains one review article, five full-length articles and two technical briefs covering spheroid models, 3D cell high-throughput screening (HTS) applications for treating Alzheimer’s and other drug discovery research.
Odontoid fractures—those occurring in the second cervical vertebra—are common in elderly patients after a low-energy fall. However, whether the initial treatment should be surgical or nonoperative still isn’t known. Previous studies haven’t accounted for differences in injury severity, or the presence or absence of neurologic impairment, which can affect patients’ results.
After an awake surgery to remove a cancerous brain tumor, a Michigan man is living “more deliberately” than ever — officiating a high school wrestling state championship and participating in research for a potential cure.
Glioblastoma cells are poised near a “critical point” of order and disorder — meaning, the cells possess some form of large-scale coordination throughout the whole tumor that allows them to respond in practical unison to attempts to kill tumor cells, such as chemotherapy or radiation, a study suggests. Researchers say disrupting the large-scale organization of brain tumors may result in more powerful ways to treat and one day eliminate brain tumors.
Sucheta Joshi, MD, MS, FAAP, FAES, has been named as incoming Medical Director of the Neurological Institute Comprehensive Epilepsy Program at Children’s Hospital Los Angeles (CHLA).
Researchers have developed the prototype of a comfortable and flexible ‘soft smart hand exoskeleton’ or robo-glove, which gives feedback to wearers who need to relearn tasks that require manual dexterity and coordination, for example after suffering a stroke. The present study focused on patients who need to relearn to play the piano as a proof-of-principle, but the glove can easily be adapted to help relearn other daily tasks.
A soft robotic glove is lending a “hand” and providing hope to piano players who have suffered a disabling stroke. Combining flexible tactile sensors, soft actuators and AI, this robotic glove is the first to “feel” the difference between correct and incorrect versions of the same song and to combine these features into a single hand exoskeleton. Unlike prior exoskeletons, this new technology provides precise force and guidance in recovering the fine finger movements required for piano playing and other complex tasks.
A new AI tool that could help doctors assess the early signs of dementia and Alzheimer’s more quickly and efficiently, has been developed by researchers at the University of Sheffield.
Benzodiazepine use and discontinuation is associated with nervous system injury and negative life effects that continue after discontinuation, according to a new study.
Chronic traumatic encephalopathy (CTE) is a degenerative brain disease linked to repeated head impacts that athletes get from contact sports. However, the definitive diagnosis of the disease can be made only after death through an autopsy.
Children who begin reading for pleasure early in life tend to perform better at cognitive tests and have better mental health when they enter adolescence, a study of more than 10,000 young adolescents in the US has found.
A group from Nagoya University in Japan has discovered that when the diet of nematodes, tiny worms measuring about a millimeter or less in length, includes the bacteria Lactobacillus reuteri, the weakening of associative learning ability caused by aging does not occur.
For many people, the day doesn’t start until their coffee mug is empty. Coffee is often thought to make you feel more alert, so people drink it to wake themselves up and improve their efficiency.
The American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM), is excited to announce Margaret A. Turk, MD, as a 2023 plenary speaker at the AANEM Annual Meeting Nov. 1-4 in Phoenix, Arizona.
The American Association of Neuromuscular & Electrodiagnostic Medicine (AANEM), is excited to announce Michael Lewis, MA, as a 2023 plenary speaker at the AANEM Annual Meeting Nov. 1-4 in Phoenix, Arizona.
A study of more than 22,000 people with multiple sclerosis has discovered the first genetic variant associated with faster disease progression, which can rob patients of their mobility and independence over time.
Three University Hospitals and Case Western Reserve University School of Medicine research teams recently received Collaborative Science Pilot Awards. The teams each received $50,000, funded by both institutions. If substantial progress is accomplished and milestones are achieved, an additional year of funding will be considered.
Co-existing use of alcohol and cannabis can lead to negative outcomes such as the development of a substance-use disorder, poor academic and occupational performance, and psychiatric disorders when compared to use of either drug alone. New research that examines simultaneous alcohol/cannabis use has found higher levels of drinking after 18 months. These results and others will be shared at the 46th annual scientific meeting of the Research Society on Alcohol (RSA) in Bellevue, Washington.
Researchers have recently begun making strides toward understanding the neurophysiology underlying different subtypes of depression, which could speed development of better treatments, but much remains to be discovered.