The Smidt Heart Institute at Cedars-Sinai has opened an Aortic Surveillance Clinic for the evaluation and long-term monitoring of patients with enlarged aortas, or aortic aneurysms, for whom surgery may not be necessary.
RUDN University agronomists have built a map of the evolution and genetic diversity of millet. This drought-resistant cereal is underestimated, but new data will help to carry out breeding and increase its yield.
Rochester, Minn. (Dec. 21, 2023)- The American Neuromuscular Foundation (ANF), is excited to announce that Erika Williams, MD, PhD, has been selected as one of the 2023 Development Grant recipients for her research project, “Genetically Decoding Human Afferent and Efferent Autonomic Ganglia.”
Rochester, Minn. (Dec. 21, 2023)- The American Neuromuscular Foundation (ANF), is excited to announce that Mai Yamakawa, MD, has been selected as one of the 2023 Development Grant recipients for her research project, “Causal Genetic Variation and Transcriptomic Signatures of the Peripheral Immune System in the Central Nervous System Pathology of ALS That Are Conserved or Divergent Among ALS Patients and the Animal Models.”
Mayo Clinic researchers mapped how the measles virus mutated and spread in the brain of a person who succumbed to a rare, lethal brain disease.
With the rise in machine learning applications and artificial intelligence, it's no wonder that more and more scientists and researchers are turning to supercomputers. Supercomputers are commonly used for making predictions with advanced modeling and simulations. This can be applied to climate research, weather forecasting, genomic sequencing, space exploration, aviation engineering and more.
A groundbreaking new technique invented by researchers at the USC Dornsife College of Letters, Arts and Science may revolutionize the field of synthetic biology. Known as CReATiNG (Cloning Reprogramming and Assembling Tiled Natural Genomic DNA), the method offers a simpler and more cost-effective approach to constructing synthetic chromosomes. It could significantly advance genetic engineering and enable a wide range of advances in medicine, biotechnology, biofuel production and even space exploration.
The Association for Molecular Pathology (AMP) has published a report that explores specific considerations for a slice testing strategy for diagnostics, including gene selection, analytic performance, coverage, quality, and interpretation.
Researchers from Karlsruhe Institute of Technology (KIT) and partners all over Germany have developed a new system for X-ray imaging, which is suited for both living specimens and sensitive materials.
Scientists at St. Jude Children’s Research Hospital identified genetic and epigenetic mechanisms driving predisposition to this childhood kidney cancer, impacting care and treatment.
Nidhi Sahni, Ph.D., associate professor of Epigenetics and Molecular Carcinogenesis at The University of Texas MD Anderson Cancer Center, has been awarded the 2024 Mary Beth Maddox Award and Lectureship in cancer research from the Texas Academy of Medicine, Engineering, Science and Technology (TAMEST).
UChicago Medicine Comer Children’s Hospital will be among the first in the country to offer gene therapy for sickle cell disease after regulators approved two new treatments.
The U.S. Food & Drug Administration has expanded the approved use of belzutifan for treatment of metastatic kidney cancer, another milestone for the novel, first-in-class kidney cancer drug arising from scientific discoveries at UT Southwestern Medical Center.
UCL researchers have developed a new gene therapy to cure a devastating form of childhood epilepsy, which a new study shows can significantly reduce seizures in mice
A new paper describes a study of antimicrobial resistance (AMR) transmission among cockroaches, with implications for AMR transmission in humans. The study was published in mSystems, a journal of the American Society for Microbiology.
Researchers have determined the structure of the most common material in our genomes. New treatments for autoimmune diseases, cancer and neurodegeneration may follow.
In a novel study, researchers from the Icahn School of Medicine at Mount Sinai introduced LoGoFunc, an advanced computational tool that predicts pathogenic gain- and loss-of-function variants across the genome.
One of the greatest philosophical thought exercises that has challenged the concept of identity, is the Ship of Theseus paradox. It poses the question: Are we the same person over time? The original meaning of ‘Identity’ is derived from Medieval Latin identitas or idem meaning ‘sameness’ or ‘same’. But ‘sameness’ has been difficult to comprehend.
Do epigenetic changes cause type 2 diabetes, or do the changes occur only after a person has become ill? A new study by researchers at Lund University provides increased support for the idea that epigenetic changes can cause type 2 diabetes.
Flat-faced dogs' popularity comes at a high cost in terms of health: shortened skulls are associated with deteriorative brain morphology changes, breathing difficulties and sleep problems.
When a sweet corn breeder reached out in 2021 to report severe injury from the herbicide tolpyralate, Marty Williams hoped it was a fluke isolated to a single inbred line. But two years later, after methodical field, greenhouse, and genetic testing, his new Pest Management Science study not only confirms sensitivity to tolpyralate in 49 sweet corn and field corn lines, but also reveals a new genetic vulnerability that may affect corn more generally.
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention.
اكتشف باحثو مايو كلينك نمطًا مميزًا في مجموعة معينة مكونة من 17 جينًا قد يكونوا مرتبطين بحدوث هدأة بعد الخضوع لعلاج سرطان الثدي الثلاثي السلبي.
Researchers from UC San Diego have come one step closer to unlocking the potential of synthetic DNA, which could help scientists develop never-before-seen proteins in the lab.
As part of a national initiative better understand how the brain works, researchers from UC San Diego have analyzed more than 2.3 million individual brain cells from mice to create a comprehensive map of the mouse brain.
A previously mysterious small RNA molecule in mice is found to play a crucial role in gene expression, and may be the first identified member of a new class of regulatory RNAs.
Pesquisadores da Mayo Clinic descobriram um padrão distinto em um conjunto específico de 17 genes que pode estar associado com a remissão após o tratamento para câncer de mama triplo negativo.
Los investigadores de Mayo Clinic han descubierto un patrón característico en un conjunto de 17 genes que podrían asociarse con la remisión después del tratamiento para el cáncer de mama triple negativo.
By monitoring changes in circulating tumor DNA (ctDNA) among 30 patients treated with immunotherapies for metastatic non-small cell lung cancers, researchers were able to determine molecular response — the clearance of tumor genetic material in the bloodstream.
Living through a historic pandemic while handling the stress of the first year of college sent one-third of students in a new study into clinical depression. That’s double the percentage seen in previous years of the same study.
New research conducted by investigators at Sylvester Comprehensive Cancer Center and collaborating cancer centers indicates that a new type of targeted therapy may offer new treatment options for patients living with advanced myelofibrosis, a bone marrow disorder. Study results will be shared at ASH 2023 in San Diego, Dec. 9-12.
It only takes holding your breath for slightly too long to understand that too little oxygen is bad for you.
It's the moooost wonderful time...of the year! Are you looking for new story ideas that are focused on the winter holiday season? Perhaps you're working on a story on on managing stress and anxiety? Perhaps you're working on a story on seasonal affective disorder? Or perhaps your editor asked you to write a story on tracking Santa? Look no further. Check out the Winter Holidays channel.
The lab of Yongchao C. Ma, PhD, at Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago uncovered a novel mechanism that leads to motor neuron degeneration in spinal muscular atrophy (SMA).
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The targeted therapy trastuzumab deruxtecan (T-Dxd), an antibody drug conjugate, is now an approved treatment of HER2-low advanced breast cancers. In a new study led by Yale Cancer Center researchers at Yale School of Medicine, their findings revealed important differences in the genetic makeup of HER2-low advanced breast cancers — a discovery that could lead to better treatment options for patients.
Researchers who have studied malaria for decades, hoping to find a cure, long thought they’d identified a type of blood that seemed to defend against the disease. But a new study published Dec. 5 in Cell Host & Microbe concludes that even some people with the protective blood type became infected. The question now is, “how?”
Patients with sickle cell disease (SCD) often face a reduced quality of life and a lower life expectancy. Allotransplantation, the first treatment for SCD with curative potential, comes with risks, including transplant-related mortality. Gene therapy, once approved for SCD, could also offer a lifelong cure without the risk associated with allotransplantation.
St. Jude researchers will participate in multiple oral and poster presentations and education sessions as well as moderate panels during the ASH conference.
A partnership between ARUP Laboratories and Medicover has made a new companion diagnostic, and thereby a new gene therapy, more accessible to patients in the European Union.
The electric eel is the biggest power-making creature on Earth. It can release up to 860 volts, which is enough to run a machine. In a recent study, a research group from Nagoya University in Japan found electric eels can release enough electricity to genetically modify small fish larvae. They published their findings in PeerJ - Life and Environment.
A new study led by UT Southwestern Medical Center molecular biologists presents a novel culture system to grow both embryonic and extraembryonic stem cells, potentially providing important insights into the genesis of congenital malformations and early developmental disorders.
Scientists attacking the problem of high miscarriage rates have long wondered if there is a way to tell whether an egg cell will successfully develop into an embryo and grow or if there is a marker indicating when it is destined to fail. Two Rutgers-led research teams have found strong clues in two separate studies using both human and mouse data that will allow them to begin to answer “yes” to both questions.
Researchers from at University of California San Diego, West Health, and the University of Washington have found evidence that the private insurers that sponsor Medicare Part D are artificially inflating the costs of certain generic drugs by overpaying pharmacies.
In a recent study, scientists led by Professor Stefan Müller from Goethe University’s Institute of Biochemistry II investigated a specific form of blood cancer known as acute myeloid leukemia, or AML. The disease mainly occurs in adulthood and often ends up being fatal for older patients.
Many of the most potent human oncoproteins belong to a class of proteins called transcription factors, but designing small molecule drugs that target transcription factors is a major challenge.
Gene expression is often regulated by chemical modifications, a process known as epigenetics for DNA and epitranscriptomics for RNA. Among these, N6-methyladenosine (m6A) is a significant internal modification of mRNA that plays crucial roles in gene expression and various biological and pathological processes, including cancer development.
A comprehensive analysis of the soybean genome can help develop improved varieties of soybean by identifying crucial genes linked to desirable traits.
A roundup of the latest medical discoveries and faculty news at Cedars-Sinai.
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