Cornell researchers have harnessed the power of baker’s yeast to create a cost-effective and highly efficient approach for unraveling how plants synthesize medicinal compounds, and used the new method to identify key enzymes in a kratom tree.
In a plant microbiome, the microbial community assembles and changes by exchanging signals between the host plant and the microbes. Researchers have gathered and filtered a large amount of data using a combination of computational approaches to identify new mechanisms in this signaling process. The study discovered a host transport mechanism and a chemical signal that influences beneficial bacterial colonization of plants’ roots.
Two participants in an NIBIB training program that aims to diversify the biomedical workforce share their stories of how the program influenced their career paths.
The first and only panel of specialty reagents designed to detect PS modifications independent of sequence, format, or location, streamlining candidate triage for unparalleled cost and time savings in non-clinical/pre-clinical discovery assessment of oligonucleotide drug candidates, clinical trials for immunogenicity studies, and other applications.
Nanozymes are synthetic materials that mimic the properties of natural enzymes for applications in biomedicine and chemical engineering. They are generally considered too toxic and expensive for use in agriculture and food science.
The Medical Imaging and Data Resource Center (MIDRC), housed at the University of Chicago, was selected in September 2023 as one of several performers for a new program aimed at optimizing biomedical data management for health research.
Biochemists from RUDN University described how to prevent cancer cells from becoming resistant to chemotherapy drugs. Having determined the resistance mechanism, biochemists selected a drug that can slow down it.
A team of European researchers has developed a new test that can accurately measure biological aging in a clinical setting. The discovery was made while studying patients for the aging effects of chronic kidney disease.
Synthetic biologists at Columbia Engineering report today a new approach to attacking tumors. They have engineered tumor-colonizing bacteria (probiotics) to produce synthetic targets in tumors that direct CAR-T cells to destroy the newly highlighted cancer cells.
Associate Professor Adeen Flinker and Professor Yao Wang co-led a team of NYU researchers that created and used complex neural networks to recreate speech from brain recordings, and then used that recreation to analyze the processes that drive human speech.
In Review of Scientific Instruments, scientists developed a microwave microstrip line planar resonator sensor tool to detect water adulteration in honey. The tool is compact, cost-effective, and easily fabricated. The microstrip line resonator sensor is fabricated on a dielectric substrate, which is an insulator that can efficiently support electrostatic fields, such as ceramic or glass. The team tested honey samples with varying water content and found that the sensor's resonance frequency consistently decreases with increased added water content.
Cedars-Sinai has selected urologic surgeon and investigator Andrew Hung, MD, as the vice chair of Academic Development in the Department of Urology with a joint appointment in the Department of Computational Biomedicine.
A technology being studied to curb climate change – one that could be put in place in one or two decades if work on the technology began now – would affect food productivity in parts of planet Earth in dramatically different ways, benefiting some areas, and adversely affecting others, according to projections prepared by a Rutgers-led team of scientists.
Today, the Mount Sinai Health System, New York City’s largest academic medical system, announced the opening of its new Discovery and Innovation Center with a ceremonial ribbon cutting. This state-of-the-art research lab will expand research capabilities in collaboration with clinical neuroscience and neurosurgery centers of excellence at Mount Sinai West.
UMass Amherst researchers have pushed forward the boundaries of biomedical engineering one hundredfold with a new method for DNA detection with unprecedented sensitivity.
Machine learning models to identify the simplest way to screen for lung cancer have been developed by researchers from UCL and the University of Cambridge, bringing personalised screening one step closer.
A biochemist who got her start at the Uniformed Services University (USU), Dr. Katalin Karikó, was awarded the Nobel Prize in Medicine on Oct. 2 for her key discoveries that led to the development of the mRNA vaccines against COVID-19.
The dew-covered spiderweb you see in your yard might soon become a platform to detect airborne viruses. This is the objective of Jiangtao Cheng, associate professor in the Department of Mechanical Engineering,.
In order to fulfil their function, biological cells need to be divided into separate reaction compartments. This is sometimes done with membranes, and sometimes without them: the spontaneous segregation of certain types of biomolecules leads to the formation of so-called condensates.
A materials scientist who specializes in superconductors, Sarrao brings a deep background in national lab leadership and the evolution of SLAC science.
Regel Therapeutics, a next generation gene therapy company utilizing proprietary technology to modulate gene expression, today announced that based upon the groundbreaking work of its Co-Founder and Chief Scientific Officer Dr. Navneet Matharu.
Cedars-Sinai recently announced the selection of Joshua Levy, PhD, as the new director of Digital Pathology Research. Levy also will hold a joint appointment in the Department of Computational Biomedicine.
Earbuds can be turned into a tool to record the electrical activity of the brain and levels of lactate in the body with two flexible sensors screen-printed onto a flexible surface.
Scientist Xiaohan Yang’s research at the Department of Energy’s Oak Ridge National Laboratory focuses on transforming plants to make them better sources of renewable energy and carbon storage.
Hedi Mattoussi, a Distinguished Research Professor with the Florida State University Department of Chemistry and Biochemistry, has been selected to receive the 2024 ACS Award in Surface Chemistry in recognition of his contributions to the advancement of surface chemistry.
BACKGROUNDHeart failure (HF) is a global health problem characterized by impaired heart function. Cardiac remodeling and cell death contribute to the development of HF. Although treatments such as digoxin and angiotensin receptor blocker dr
BACKGROUNDAcute lung injury (ALI) and its final severe stage, acute respiratory distress syndrome, are associated with high morbidity and mortality rates in patients due to the lack of effective specific treatments. Gut microbiota homeostas
BACKGROUNDUmbilical cord (UC) mesenchymal stem cell (MSC) transplantation is a potential therapeutic intervention for atherosclerotic vascular disease. Integrin beta 3 (ITGB3) promotes cell migration in several cell types. However, whether
BACKGROUNDRapid wound healing remains a pressing clinical challenge, necessitating studies to hasten this process. A promising approach involves the utilization of human umbilical cord mesenchymal stem cells (hUC-MSCs) derived exosomes. The
The National Science Foundation (NSF) has awarded a $2 million grant to researchers who are developing new functional materials to separate and recover rare-earth elements and platinum group metals from waste streams of U.S. mines.
Bio-based asphalt binder can replace petroleum based products, known as bitumen, to reduce toxic fumes, increase worker safety and enhance surface sustainability.
Engineers and chemists at Lawrence Livermore National Laboratory and Meta have developed a new kind of 3D-printed material capable of replicating characteristics of biological tissue, an advancement that could impact the future of “augmented humanity.”
Texas Biomedical Research Institute has created a new global center to foster collaborations in infectious disease research. The International Center for the Advancement of Research & Education (I·CARE) leverages the power of global exchange to solve complex health issues in an increasingly connected world.
Zhijian “James” Chen, Ph.D., Professor of Molecular Biology at UT Southwestern Medical Center, has been awarded the 2023 Louisa Gross Horwitz Prize in recognition of his groundbreaking work on innate immunity.
In August 2023, Americans made nearly a million calls for help to the 211 emergency resources helpline, according to 211 Counts, a national tracking system in 36 states developed by the Brown School’s Health Communication Research Laboratory at Washington University in St. Louis.
No longer limited to the realm of science fiction, bio-computing is here, so now is the time to start considering how to research and apply this technology responsibly, an international group of experts says.
Researchers have proposed a novel strategy for the development of sustainable and degradable bioplastics. This starch plastics, which possess integrated advantages including superior flexibility, excellent thermal processability, waterproof capability, solvent resistance, and self-healing ability, demonstrate immense potential as a viable substitute to petroleum-based plastics.
Berkeley Lab scientists are accelerating and streamlining the process of engineering microbes to produce important compounds with commercial-ready efficiency.
The algorithm found patterns to help identify the citations that were more likely to be important to each piece of published science. Those results revealed NIH-funded basic biological science appearing in the weightier citations at a rate three times the size of its share of all published research.
Nebraska researchers are converting plant wastes into antimicrobial agents that could help prevent pathogenic infections and death while significantly lowering the cost of antimicrobial treatments and being a boon to the bioeconomy.