You may remember a loved one making you a bowl of chicken noodle soup whenever you were feeling under the weather as a child. Just how healthy is this culinary cure-all? BIDMC clinical dietitian Sandy Allonen, RD, weighs in.
A team that includes researchers from the Bridge Institute at the University of Southern California (USC) and the Department of Energy’s SLAC National Accelerator Laboratory used X-rays to map the shape of a receptor in the body as it binds with misoprostol. This research, published in Nature Chemical Biology, could help in the quest to design low-cost drugs that can tackle postpartum bleeding without affecting other tissues.
The PhRMA Foundation awarded more than $6 million over the last two years to more than 100 leaders in scientific research in the United States. The Foundation is proud to announce another successful year supporting innovative research efforts in areas of great importance: Alzheimer’s Disease, Melanoma, Parkinson’s Disease, Schizophrenia, Breast Cancer, Lung Cancer, Leukemia, Ulcerative Colitis, Vascular Disease, and Colorectal Cancer. This year the Foundation also funded two Centers of Excellence in Value Assessment.
Together with colleagues from Sweden and Luxembourg, scientists from the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have observed that, during a natural vaginal birth, specific bacteria from the mother's gut are passed on to the baby and stimulate the baby's immune responses. This transmission is impacted in children born by caesarean section.
Moores Cancer Center at UC San Diego Health launched the Pancreatic Cancer Prevention and Screening Clinic in an attempt to reduce the number of people who develop the disease and improve survival for those who do. Every day in the U.S., 145 people are diagnosed and every 12 minutes someone dies.
Richard Goldberg, who directs the West Virginia University Cancer Institute, is searching for new ways to slow colorectal cancer’s progression. In a recent study, he and an international team of scientists investigated a new drug combination for treating metastatic colorectal cancer in patients who had no—or only temporary—success with conventional chemotherapy treatments.
An undergraduate researcher is identifying bacteria that can potentially help improve gut health by colonizing the gut mucosal layer and stimulating the immune system.
Millions of Americans have no idea that they have fatty liver disease. This growing problem will soon be the number one reason for liver transplantation, overtaking hepatitis C. Holiday overindulgence in alcohol and food could make the problem dramatically worse.
Are there changes that affect genes and fuel a person’s propensity to develop obesity? That’s a question under study at Texas Biomedical Research Institute. Associate Scientist Melanie Carless, Ph.D., is Principal Investigator of a $3 million, four-year grant from the National Institute of Diabetes, Digestive and Kidney Diseases to research this hypothesis.
While probiotics are often used to treat acute gastroenteritis (also known as infectious diarrhea) in children, the latest evidence shows no significant differences in outcomes, compared to a placebo.
• $1 million in initial funding to evaluate DNA repair inhibitors in pancreatic cancer
• Aim to accelerate pancreatic cancer research and improve patient outcomes for pancreatic cancer
An experimental drug may be effective against a deadly form of pancreatic cancer when used in combination with other immune-boosting therapies, according to a cover study publishing online Nov. 12 in Cancer Cell.
For the first time, transplanting gut bacteria from healthy donors was used to successfully treat patients suffering from severe colitis caused by treatment with immune checkpoint inhibitors. The study from The University of Texas MD Anderson Cancer Center, which includes two patients, suggests fecal microbiota transplantation is worth investigating in clinical trials as a therapy for this common side effect of immunotherapy.
Oregon State University College of Engineering researchers have developed a means of printing transistor-based glucose sensors directly onto a catheter attached to a wearable pump. The catheter’s integrated electronics transmit blood sugar levels to the computerized pump, ensuring that diabetics get the insulin and glucagon they need, when they need it.
With only 13 genes, human mitochondria are massively overshadowed by the 20,000 genes in the human nucleus. Nevertheless, these diminutive organelles may have a strong influence on cellular metabolism and susceptibility to metabolic diseases like heart failure or obesity.
Novembro é o mês de conscientização sobre a C. diff, um período para se concentrar em aumentar a conscientização sobre a prevenção e o tratamento de infecções causadas pela Clostridium Difficile. "A C. diff é uma infecção bacteriana que causa sintomas que vão desde a diarreia à inflamação grave do colón", diz Darrell Pardi, M.D., um gastroenterologista da Mayo Clinic.
Noviembre es el mes de concienciación sobre el Clostridium difficile (C. difficile), lo que brinda un momento para enfocarse en concienciar más a la gente acerca de la prevención y tratamiento de las infecciones por Clostridium difficile.
Serotonin (3A) receptors are common drug targets in the treatment of pain, gastrointestinal dysfunctions, and mood disorders yet little is known about their three-dimensional structure. Details about serotonin receptor structures could provide important clues to designing better drugs with less side effects. Now, a team of researchers from Case Western Reserve University School of Medicine have used high-powered microscopes to view serotonin activating its receptor for the first time. Images published in Nature reveal molecular details about the receptor that could improve drug design to treat a multitude of diseases.
Researchers at the University of Minnesota and the Somali, Latino, and Hmong Partnership for Health and Wellness have new evidence that the gut microbiota of immigrants and refugees rapidly Westernize after a person’s arrival in the United States. The study could provide insight into fighting obesity and diabetes.
November is C. diff awareness month, a time to focus on raising awareness about the prevention and treatment of Clostridium Difficile Infections. Mayo Clinic experts are available for interviews.
The American Society for Biochemistry and Molecular Biology announced today that Kerry-Anne Rye of the University of New South Wales Sydney and Nicholas O. Davidson of Washington University in St. Louis will be the next editors-in-chief of the Journal of Lipid Research.
Infants born at home have more diverse bacteria in their guts and feces, which may affect their developing immunity and metabolism, according to a study in Scientific Reports.
Children who are given antibiotics or antacids in their first two years of life are more likely to become obese during their childhood, according to a new study published today in the British Medical Journal, Gut.
The UNC School of Medicine is one of four clinical sites, funded by a new five-year, $10 million NIH grant, that will identify the most effective treatment options for patients with accidental bowel leakage (ABL), which is also known as fecal incontinence (FI).
Baby formula is designed to mimic human breast milk as closely as possible. A new study from Washington University School of Medicine in St. Louis finds that formula and breast milk nurture the growth of intestinal bacteria capable of producing differing metabolites. The health implications of these differences are unknown.
FSU researchers found that consuming 30 grams of protein about 30 minutes before bed appears to have a positive effect on muscle quality, metabolism and overall health. And for those who have sworn off eating at night, there is no gain in body fat.
The American College of Gastroenterology will donate $1,000 to charity for any tips that lead to the location and safe return of the stolen inflatable colon.
In a discovery that may have significant impact on the future of colon cancer treatment and research, scientists at the Helen F. Graham Cancer & Research Institute’s Center for Translational Cancer Research at Christiana Care Health System have defined a key signaling pathway that regulates colon cancer growth.
The mechanism leading to development of type 1 diabetes remains a mystery, hampering the ability to find new ways to prevent, treat or even cure this condition. With a new $3.3 million grant, University of California School of Medicine researchers hope to create a high resolution reference map of pancreatic cells that will identify molecular changes that arise during type 1 diabetes.
Overactive bladder (OAB) is a common form of urinary incontinence that is widely treated with pelvic floor muscle (PFM) training. A new laboratory study lends insights into how PFM training works: by reducing contractions of the detrusor muscle of the bladder, reports the American Journal of Physical Medicine & Rehabilitation, the official journal of the Association of Academic Physiatrists. The journal is published by Wolters Kluwer.
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health (NIH), has awarded Brian Schmidt, DDS, MD, PhD, director of the Bluestone Center for Clinical Research at New York University College of Dentistry (NYU Dentistry) and Nigel Bunnett, PhD, professor in the Departments of Surgery and Pharmacology at Columbia University, a joint $2.7 million, 3.5-year grant to study Protease-Activated Receptor 2 (PAR2) and pain signaling. The study will help determine whether PAR2 can be exploited as a therapeutic target to treat chronic pain.
Crohn’s disease (CD), a chronic inflammatory condition of the intestinal tract, has emerged as a global disease, with rates steadily increasing over the last 50 years. Experts have long suspected that CD likely represents a collection of related but slightly different disorders, but until now it has not been possible to predict accurately which subtype of CD a patient is likely to develop. In a study published Oct. 4 in the journal JCI Insight, Cornell University and University of North Carolina researchers report they have pinpointed a single molecule – microRNA-31 (miR-31) – the levels of which predict whether a patient has subtype 1 or subtype 2 of the disease.
Women who are overweight or obese have up to twice the risk of developing colorectal cancer before age 50 as women who have what is considered a normal body mass index (BMI), according to new research led by Washington University School of Medicine in St. Louis.
In studies of mouse cells, Johns Hopkins researchers have found that low levels of cellular copper appear to make fat cells fatter by altering how cells process their main metabolic fuels, such as fat and sugar.
A new study from Tufts researchers finds that two inflammatory proteins in the colon increase incrementally with weight. In individuals with obesity, this was accompanied by activation of precancerous cellular pathways.
A bacterium known for causing stomach cancer might also increase the risk of certain colorectal cancers, particularly among African Americans, according to a study led by Duke Cancer Institute researchers.
This month's tip sheet from Fred Hutch highlights research related to cancer-causing bacteria, a cancer 'escape hatch,' how sex cells sort chromosomes, cord blood's role in leukemia treatment and more.
The Maryland Proton Treatment Center (MPTC) is now offering deep-tissue external thermal therapy in combination with high-precision proton-beam radiotherapy as a potential way to boost survival chances for certain cancer patients. MPTC is the only center in the world to offer these two treatments at the same facility, an advantage to patients because these therapies are typically given within an hour of each other.
Philadelphia, PA (October 8, 2018) – More than 5,000 gastroenterologists and other health care professionals will convene at the Pennsylvania Convention Center in Philadelphia, PA for the premier clinical gastroenterology event—the American College of Gastroenterology’s 83rd Annual Scientific Meeting and Postgraduate Course (ACG 2018)—to review the latest scientific advances in gastrointestinal research, treatment of digestive diseases and clinical practice management.
Philadelphia, PA (October 8, 2018) – Sunanda V. Kane, MD, MSPH, FACG, a gastroenterologist and Professor of Medicine at Mayo Clinic Rochester, MN, was elected by the membership as the 2018-2019 President of the American College of Gastroenterology (ACG), a national medical organization representing more than 14,000 clinical gastroenterologists and other specialists in digestive diseases.
Scientists from the Cancer Science Institute of Singaporeat the National University of Singapore have discovered a new molecular pathway that controls colorectal cancer development, and their exciting findings open new therapeutic opportunities.
Philadelphia, PA (October 5, 2018) – The American College of Gastroenterology (ACG) announces the winners of the 2018 SCOPY Awards (Service Award for Colorectal Cancer Outreach, Prevention and Year-Round Excellence) to recognize the achievements of ACG members in their community engagement, education and awareness efforts for colorectal cancer prevention.
Some people suffer unpredictable bouts of abdominal pain and constipation. A new study in mice, from Washington University School of Medicine in St. Louis, shows that viruses that target the nervous system can kill neurons in the gut that coordinate the process of moving waste along. Such viruses may be involved in causing people's digestive woes.